Cheap Flights from Panama City (PTY) to San Francisco (SFO) from HK$2,713~

View HK$2,713 flight on Wed, 24 Dec 2025Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to San Francisco Intl. Airport (SFO)

  • notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
  • deals illustration

    Book smarter

    Save up to 35% on select hotels after you book a flight*
  • trophy illustration

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Find Cheap Flights from Panama City (PTY) to San Francisco (SFO)

Prices were available within the past 7 days and start at HK$2,713 for one-way flights and HK$6,013 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aeromexico
Wed, 24 Dec - Sun, 28 Dec
PTY
Panama City
SFO
San Francisco
HK$6,013 Return, found 1 day ago
HK$6,013
Return
found 1 day ago
Select Aeromexico flight, departing Wed, 24 Dec from Panama City to San Francisco, returning Sun, 28 Dec, priced at HK$6,013 found 1 day ago
American Airlines
Fri, 10 Apr - Wed, 15 Apr
PTY
Panama City
SFO
San Francisco
HK$6,015 Return, found 2 days ago
HK$6,015
Return
found 2 days ago
Select American Airlines flight, departing Fri, 10 Apr from Panama City to San Francisco, returning Wed, 15 Apr, priced at HK$6,015 found 2 days ago
Copa
Sat, 28 Mar - Wed, 1 Apr
PTY
Panama City
SFO
San Francisco
HK$6,238 Return, found 2 days ago
HK$6,238
Return
found 2 days ago
Select Copa flight, departing Sat, 28 Mar from Panama City to San Francisco, returning Wed, 1 Apr, priced at HK$6,238 found 2 days ago
Copa
Sat, 28 Mar - Wed, 1 Apr
PTY
Panama City
SFO
San Francisco
HK$6,367 Return, found 2 days ago
HK$6,367
Return
found 2 days ago
Select Copa flight, departing Sat, 28 Mar from Panama City to San Francisco, returning Wed, 1 Apr, priced at HK$6,367 found 2 days ago
Copa
Fri, 10 Apr - Wed, 15 Apr
PTY
Panama City
SFO
San Francisco
HK$6,549 Return, found 2 days ago
HK$6,549
Return
found 2 days ago
Select Copa flight, departing Fri, 10 Apr from Panama City to San Francisco, returning Wed, 15 Apr, priced at HK$6,549 found 2 days ago
American Airlines
Sat, 28 Mar - Wed, 1 Apr
PTY
Panama City
SFO
San Francisco
HK$6,647 Return, found 2 days ago
HK$6,647
Return
found 2 days ago
Select American Airlines flight, departing Sat, 28 Mar from Panama City to San Francisco, returning Wed, 1 Apr, priced at HK$6,647 found 2 days ago
Copa
Fri, 10 Apr - Wed, 15 Apr
PTY
Panama City
SFO
San Francisco
HK$6,795 Return, found 2 days ago
HK$6,795
Return
found 2 days ago
Select Copa flight, departing Fri, 10 Apr from Panama City to San Francisco, returning Wed, 15 Apr, priced at HK$6,795 found 2 days ago
American Airlines
Fri, 10 Apr - Wed, 15 Apr
PTY
Panama City
SFO
San Francisco
HK$7,107 Return, found 2 days ago
HK$7,107
Return
found 2 days ago
Select American Airlines flight, departing Fri, 10 Apr from Panama City to San Francisco, returning Wed, 15 Apr, priced at HK$7,107 found 2 days ago
United
Fri, 10 Apr - Wed, 15 Apr
PTY
Panama City
SFO
San Francisco
HK$7,139 Return, found 2 days ago
HK$7,139
Return
found 2 days ago
Select United flight, departing Fri, 10 Apr from Panama City to San Francisco, returning Wed, 15 Apr, priced at HK$7,139 found 2 days ago
avianca
Fri, 10 Apr - Wed, 15 Apr
PTY
Panama City
SFO
San Francisco
HK$8,449 Return, found 2 days ago
HK$8,449
Return
found 2 days ago
Select avianca flight, departing Fri, 10 Apr from Panama City to San Francisco, returning Wed, 15 Apr, priced at HK$8,449 found 2 days ago

Find the cheapest month to fly from Panama City (PTY) to San Francisco (SFO)

September is typically the cheapest month to fly

From HK$3,656 - HK$5,141 per traveller.

Alternative airports near San Francisco

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to San Francisco Intl. SFO. Cheapest and Closest option available. Average driving time to city centre is 19 minutes. Flights from HK$8,175
SFO
San Francisco Intl.
CheapestClosest
Average driving time to city centre19 min
Flights from HK$8,175
Panama City to San Francisco route information
Origin airport
Tocumen Intl.
Destination airport
San Francisco Intl.
Airlines serving
American Airlines, Copa, Delta, United
Return price
HK$6,013
Distance
5313 km
Average flight time
4 hours 52 mins

Flights from Tocumen to San Francisco

Book cheap flights from Tocumen (PTY) to San Francisco (SFO) on Expedia.com.hk. Find the best flight deals to destinations around the world for your next leisure or business travel on Expedia.com.hk.

Search for flights from Tocumen (PTY) to San Francisco (SFO) to find great flight deals suitable to your travel date and time. Expedia.com.hk flight booking search engine is simple to use and looking for cheap flights is as easy as a click of a mouse or on your mobile devices.

Be assured that you’re seeing the best price guaranteed! Our friendly customer service representatives are here to serve you 24 hours day to provide assistance and answer any questions that you may have about booking your Tocumen (PTY) to San Francisco (SFO) trip. Call us at 3077-4857 (direct number - 24 hours day for English).

Save more when combine your San Francisco flight with a hotel for a package deal! Discover additional savings by booking in advance. Now you can find activities in San Francisco and things to do in San Francisco for your perfect vacation with Expedia Thing to Do.

If you would like to book flights to San Francisco more flexibly, many prefer to purchase one-way tickets with options to take different airlines. A one way ticket to San Francisco is HK$2,713 now!

 

Frequently asked questions

How much is a flight from PTY to San Francisco Intl. Airport (SFO)?
Based on fares offered within the last 7 days on Expedia for flights departing within the next year, round-trip journeys from PTY to San Francisco Intl. Airport (SFO) start from HK$6,013. Make your booking ASAP to get the best price for your adventure. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from Tocumen Intl. Airport (PTY) to San Francisco Airport?
We understand that things crop up unexpectedly, so we've made it as hassle-free as possible for you to cancel your flight online. Just head to the Customer Service Portal and follow the instructions.
How do I find cheap flights from PTY to San Francisco Airport that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for Panama Airport to San Francisco Airport flights, you'll see a "no change fees" filter for you to select.
How far is the flight from Panama Airport to San Francisco Airport?
With around 5,400 kilometers separating Tocumen and San Francisco, your flight will be a long one. Pack wisely to make your trip comfortable. Things like a sleep mask and a quality neck pillow can make all the difference.
Which airlines fly direct from Tocumen Intl. Airport (PTY) to San Francisco Intl. Airport (SFO)?
Flying nonstop from PTY to SFO is a breeze with Copa Airlines (CM). This popular carrier operates 30 flights each month.
Are Tocumen Intl. Airport (PTY) to SFO flight tickets cheaper when they're purchased at the last minute?
It is possible to nab great last-minute deals from Tocumen Intl. Airport (PTY) to San Francisco Intl. Airport (SFO), but there's no guarantee. As many airlines release seats up to 12 months in advance, it's worthwhile keeping an eye on fares early and being ready to book when you spot a bargain. Expedia compares carrier prices and updates flight deals regularly, so you can feel confident knowing you're always seeing the latest offers.

Explore a world of travel with Expedia

*Available to Expedia members.