Best Effingham Hotels in 2026 from HK$493 - Fully Refundable Options

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Our top choices for Effingham hotels

1. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Florence

Leigh

HK$925

HK$1,036 total

includes taxes & fees

19 Sept - 20 Sept

2. Comfort Inn & Suites Florence Center Area

Florence

Mike

HK$832

HK$932 total

includes taxes & fees

27 Sept - 28 Sept

3. Hyatt Place Florence Downtown

Florence

Brian

HK$894

HK$1,001 total

includes taxes & fees

7 Sept - 8 Sept

4. Home2 Suites by Hilton Florence, SC

Florence

saleh

HK$797

HK$924 total

includes taxes & fees

27 Sept - 28 Sept

5. Hampton Inn & Suites Florence Center

Florence

Jennifer

HK$861

HK$965 total

includes taxes & fees

13 Sept - 14 Sept

6. Staybridge Suites Florence - Civic Center by IHG

Florence

Frederick

HK$1,058

HK$1,185 total

includes taxes & fees

13 Sept - 14 Sept

7. Fairfield Inn & Suites by Marriott Florence I-20

Florence

leslie

HK$993

HK$1,112 total

includes taxes & fees

7 Sept - 8 Sept

8. SpringHill Suites by Marriott Florence

Florence

HK$693

HK$823 total

includes taxes & fees

13 Sept - 14 Sept

9. Homewood Suites by Hilton Florence

Florence

Anthony

HK$848

HK$1,027 total

includes taxes & fees

20 Sept - 21 Sept

10. Park Inn by Radisson Florence, SC

Florence

Hector

HK$626

HK$701 total

includes taxes & fees

7 Sept - 8 Sept

11. The Inn at the Crossroads

Lake City

Paige

HK$774

HK$866 total

includes taxes & fees

6 Sept - 7 Sept

12. Hotel Florence, Tapestry Collection by Hilton

Florence

Ankh

HK$1,086

HK$1,217 total

includes taxes & fees

11 Sept - 12 Sept

13. TownePlace Suites by Marriott Florence

Florence

William

HK$893

HK$1,000 total

includes taxes & fees

10 Sept - 11 Sept

14. Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Florence

Gerson

HK$964

HK$1,158 total

includes taxes & fees

27 Sept - 28 Sept

15. Quality Inn & Suites Florence Civic Center

Florence

Noémie

HK$686

HK$769 total

includes taxes & fees

27 Sept - 28 Sept

16. Comfort Suites Florence I-95

Florence

Jennifer

HK$693

HK$808 total

includes taxes & fees

20 Sept - 21 Sept

17. Hampton Inn & Suites Florence-North-I-95

Florence

Michelle

HK$926

HK$1,037 total

includes taxes & fees

9 Sept - 10 Sept

18. Residence Inn Marriott Florence

Florence

TERRENCE

HK$840

HK$941 total

includes taxes & fees

13 Sept - 14 Sept

19. Howard Johnson by Wyndham Florence

Florence

HOMERO

HK$500

HK$560 total

includes taxes & fees

30 Aug - 31 Aug

20. Hilton Garden Inn Florence

Florence

Derrick

HK$893

HK$1,001 total

includes taxes & fees

13 Sept - 14 Sept

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Top Effingham Hotel Reviews

Park Inn by Radisson Florence, SC

8/10 Good

"Clean, updated room. Comfortable bed. Free breakfast. Conveniently off interstate. Food options close/delivered."

Comfort Inn & Suites Florence Center Area

8/10 Good

"Nice, comfortable place to stay for one night. The carpets were a little frayed but the hotel was clean and spacious. The breakfast was very good for a continental breakfast."

Howard Johnson by Wyndham Florence

10/10 Excellent

"Everything was great"

Hyatt Place Florence Downtown

10/10 Excellent

"Staff was friendly. Room was immaculate. Breakfast was delicious. I loved the pancake machine."

La Quinta Inn & Suites by Wyndham Florence

10/10 Excellent

"Great location. Clean."

The Inn at the Crossroads

10/10 Excellent

"Everyone was very nice and everything"

More cheap stays in Effingham

Days Inn by Wyndham Florence/I-95 North

2111 West Lucas St/I-95 Florence SC

HK$440

HK$493 total

14 Sept - 15 Sept

includes taxes & fees

Howard Johnson by Wyndham Florence

2038 W Lucas Street Florence SC

HK$500

HK$560 total

30 Aug - 31 Aug

includes taxes & fees

8.6/10 Excellent! (2,711 reviews)

Park Inn by Radisson Florence, SC

1729 Mandeville Road Florence SC

HK$626

HK$701 total

7 Sept - 8 Sept

includes taxes & fees

9/10 Wonderful! (2,406 reviews)

Quality Inn & Suites Florence Civic Center

150 Dunbarton Dr Florence SC

HK$686

HK$769 total

27 Sept - 28 Sept

includes taxes & fees

Comfort Inn & Suites Florence Center Area

527 Woody Jones Blvd Florence SC

HK$832

HK$932 total

27 Sept - 28 Sept

includes taxes & fees

9/10 Wonderful! (1,352 reviews)

Hampton Inn & Suites Florence Center

3000 W Radio Dr Florence SC

HK$861

HK$965 total

13 Sept - 14 Sept

includes taxes & fees

Frequently asked questions

Where is the best place to stay in Effingham?

Quality Inn & Suites Florence Civic Center, located 10.5 mi (16.9 km) from the heart of Effingham, is a top choice for your stay, based on our traveller data. Other good options for your trip to the area are Park Inn by Radisson Florence, SC and Howard Johnson by Wyndham Florence. See all available top hotels, or vacation rentals in Effingham.

What are some of the best holiday rentals that Effingham has to offer?

Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's: This holiday home rental outside of Effingham offers a fireplace, a patio and air conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Make the most of garden in this rental home to help you unwind. See all vacation rentals in Effingham.

If I need to cancel my hotel reservation in Effingham, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Effingham.

What's it like to stay in Effingham?

Travellers to Effingham will find plenty to explore and enjoy. There are 159 hotels and other accommodation options in the surrounding area. Find out more about Effingham.

What should I see while I'm in Effingham?

A favourite place to visit is Lynches River State Park. You'll also find Florence National Cemetery and Florence County Museum in the area. Take a look at what more there is to see and do in Expedia's Effingham guide.

What's the seasonal weather in Effingham?

The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 10°C. Average annual precipitation for Effingham is 1366 mm.

Effingham hotels from HK$493

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Effingham

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Effingham hotels

1. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

2. Comfort Inn & Suites Florence Center Area

3. Hyatt Place Florence Downtown

4. Home2 Suites by Hilton Florence, SC

5. Hampton Inn & Suites Florence Center

6. Staybridge Suites Florence - Civic Center by IHG

7. Fairfield Inn & Suites by Marriott Florence I-20

8. SpringHill Suites by Marriott Florence

9. Homewood Suites by Hilton Florence

10. Park Inn by Radisson Florence, SC

11. The Inn at the Crossroads

12. Hotel Florence, Tapestry Collection by Hilton

13. TownePlace Suites by Marriott Florence

14. Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

15. Quality Inn & Suites Florence Civic Center

16. Comfort Suites Florence I-95

17. Hampton Inn & Suites Florence-North-I-95

18. Residence Inn Marriott Florence

19. Howard Johnson by Wyndham Florence

20. Hilton Garden Inn Florence

Top Effingham Hotel Reviews

Park Inn by Radisson Florence, SC

Comfort Inn & Suites Florence Center Area

Howard Johnson by Wyndham Florence

Hyatt Place Florence Downtown

La Quinta Inn & Suites by Wyndham Florence

The Inn at the Crossroads

More cheap stays in Effingham

Days Inn by Wyndham Florence/I-95 North

Howard Johnson by Wyndham Florence

Park Inn by Radisson Florence, SC

Quality Inn & Suites Florence Civic Center

Comfort Inn & Suites Florence Center Area

Hampton Inn & Suites Florence Center

Frequently asked questions

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