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Southeastern Indiana 4 Stars Hotels

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Check availability on Southeastern Indiana 4 Star Hotels

Tonight
24 Dec - 25 Dec
Tomorrow
25 Dec - 26 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

Our top choices for Southeastern Indiana 4-star hotels

4 restaurants, breakfast, lunch, dinner served; American cuisine
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (3881)
"Great place to stay! "
United States
Rochelle
The price is HK$1,037
HK$1,220 total
includes taxes & fees
30 Dec - 31 Dec
Galt House Hotel Trademark Collection by Wyndham
Sauna, body treatments, aromatherapy, hot stone massages
Omni Louisville Hotel

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1738)
"This is a beautiful hotel in a great location. Very kind staff and helpful with directions."
United States
Bonnie
The price is HK$1,300
HK$1,530 total
includes taxes & fees
4 Jan - 5 Jan 2026
Omni Louisville Hotel
Dinner served
Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1121)
"Staff was courteous, hotel was beautiful and clean, and breakfast was amazing!"
United States
Shunskis
The price is HK$893
HK$1,051 total
includes taxes & fees
30 Dec - 31 Dec
Embassy Suites Louisville Downtown
Lobby
The Brown Hotel

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1157)
"Fantastic place to stay in Louisville."
United States
Nathaniel
The Brown Hotel
Hypo-allergenic bedding, in-room safe, desk, laptop workspace
Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1019)
"Great location and accommodations."
United States
Steve
The price is HK$988
HK$1,162 total
includes taxes & fees
30 Dec - 31 Dec
Hotel Genevieve part of JdV by Hyatt
Front of property
21c Museum Hotel Louisville

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1000)
"Staff was very kind, the art was fantastic, location was perfect to explore Whiskey Row, and we had a gorgeous room. Loved our time away there!"
United States
Tammy
The price is HK$1,081
HK$1,311 total
includes taxes & fees
7 Jan - 8 Jan 2026
21c Museum Hotel Louisville
Breakfast, lunch and dinner served
Hyatt Regency Louisville

Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
Downtown Louisville
8.8 out of 10, Excellent, (1001)
"Enjoyed our stay "
United States
Jedediah
The price is HK$988
HK$1,162 total
includes taxes & fees
27 Dec - 28 Dec
Hyatt Regency Louisville
View from room
The Grady

The Grady

The Grady
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1005)
"Such an amazing hotel...restaurant is delicious! "
United States
Craig
The price is HK$1,127
HK$1,326 total
includes taxes & fees
4 Jan - 5 Jan 2026
The Grady
Restaurant
Louisville Marriott Downtown

Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1000)
"Very nice hotel. Great stay!"
United States
Brad
The price is HK$1,304
HK$1,535 total
includes taxes & fees
18 Jan - 19 Jan 2026
Louisville Marriott Downtown
Exterior
Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville
9.6 out of 10, Exceptional, (428)
"Great location. Great restraunt, great staff. Pleasurable experience!"
United States
Harrison
The price is HK$1,362
HK$1,603 total
includes taxes & fees
11 Jan - 12 Jan 2026
Hotel Distil, Autograph Collection
Exterior
Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (56)
"Amazing property! Best hotel in Louisville! Will be staying there again!"
United States
Norman
The price is HK$1,309
HK$1,540 total
includes taxes & fees
1 Jan - 2 Jan 2026
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Lobby
Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
Downtown Louisville
8.6 out of 10, Excellent, (1001)
"Excellent location and a great lobby bar with a top notch bourbon selection. "
United States
vincent
The price is HK$1,073
HK$1,263 total
includes taxes & fees
27 Dec - 28 Dec
Seelbach Hilton Louisville Downtown
Premium bedding, down duvets, memory-foam beds, individually furnished
Stellar Suites

Stellar Suites

Stellar Suites
4.5 star property
Downtown Louisville
9.6 out of 10, Exceptional, (117)
"Clean and great location "
United States
Greg
The price is HK$899
HK$1,450 total
includes taxes & fees
17 Jan - 18 Jan 2026
Stellar Suites
Balcony
The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B
4.0 star property
New Albany
9.8 out of 10, Exceptional, (649)
"Have stayed here once before. Accommodations are wonderful and the sit down breakfast is lovely. Highly recommend this beautiful property."
United States
Kathy
The price is HK$691
HK$781 total
includes taxes & fees
25 Dec - 26 Dec
The Pepin Mansion Historic B&B
Seasonal outdoor pool
CozySuites at Nulu

CozySuites at Nulu

CozySuites at Nulu
4.0 star property
Downtown Louisville
8.2 out of 10, Very good, (26)
"The unit was clean, all communications were timely, the property has all the amenities, and NULU is very walkable. A perfect stay! My only regret is that I wasn't able to extend the stay. Highly recommended if you're in the Louisville area "
United States
William
The price is HK$465
HK$1,443 total
includes taxes & fees
22 Jan - 23 Jan 2026
CozySuites at Nulu
BBQ/picnic Area
stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville
4.0 star property
Clarksville
9.8 out of 10, Exceptional, (43)
"Excellent stay. One of my favorite hotels in the area. They never disappoint "
United States
Julia
The price is HK$1,147
HK$1,297 total
includes taxes & fees
27 Dec - 28 Dec
stayAPT Suites Louisville North-Clarksville
Full-sized fridge, microwave, oven, stovetop
The Reserve on Main

The Reserve on Main

The Reserve on Main
4.0 star property
Downtown Louisville
10.0 out of 10, Exceptional, (1)
"Incredible stay. This stay was clean and inspiring for anyone wishing to take a break and recharge. We highly recommend this stay to everyone staying in the city. "
Canada
georgios
The price is HK$1,283
HK$1,878 total
includes taxes & fees
28 Dec - 29 Dec
The Reserve on Main
Exterior detail
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
4.0 star property
Sellersburg
9.4 out of 10, Exceptional, (10)
"Very nice house in a nice neighborhood, spacious home environmental, felt more that at home there,"
United States
Tammy
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
Private kitchen
TWO Stunning Nulu CozySuites

TWO Stunning Nulu CozySuites

TWO Stunning Nulu CozySuites
4.0 star property
Downtown Louisville
The price is HK$2,801
HK$5,680 total
includes taxes & fees
27 Dec - 28 Dec
TWO Stunning Nulu CozySuites
Front of property
Hawthorn Suites by Wyndham Louisville North

Hawthorn Suites by Wyndham Louisville North

Hawthorn Suites by Wyndham Louisville North
4.5 star property
Jeffersonville
7.4 out of 10, Good, (944)
"I would say that the hotel is in pretty good shape. The rooms are very nice. The parking lot however had a ton of people just hanging out. It made it a bit uncomfortable"
United States
alexis
Hawthorn Suites by Wyndham Louisville North
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Learn more about Southeastern Indiana

Explore lots to see and do in Southeastern Indiana—live music, sports teams and sights from Deam Lake State Recreation Area to Huber’s Orchard, Winery & Vineyards.

See all hotels in Southeastern Indiana
Bathe in the forest...find this on the roof of the outdoor shower house down the hill from the guest house.
Photo by Serendipity Trip
Open Photo by Serendipity Trip

Top Southeastern Indiana Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Southeastern Indiana?
You'll find an array of 4-star hotels in Southeastern Indiana, including in Louisville. Galt House Hotel Trademark Collection by Wyndham is a guest favourite in this city that offers concierge services and massage services. Another property that gets excellent reviews from travellers is Hyatt Regency Louisville. A swimming pool and concierge services help make it a top choice.
How much does it cost to stay in a 4-star hotel in Southeastern Indiana?
Expedia can help you easily track down the ideal 4-star hotel for your holiday in Southeastern Indiana. Use our filter tool to fine-tune your search by things like price, amenities and hotel star rating and get access to fantastic deals in a few clicks.

  • Search for the lowest price from HK$781

What's the difference between 5-star and 4-star hotels in Southeastern Indiana?
If you decide to book a stay at a 4-star hotel in Southeastern Indiana, you'll usually find plenty of conveniences to make sure you're relaxed, such as a gym, restaurant and pool. You can look forward to excellent service and upmarket surroundings. Choose a 5-star hotel and you'll have access to a few more perks — think on-site spas, around-the-clock concierge and indulgent turndown services. You're likely to get additional amenities and first-rate services at a 5-star stay, but both are terrific options for luxury guests.

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