
Southern Indiana 5 Stars Hotels
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check availability on Southern Indiana 5 Star Hotels
Tonight
21 Aug - 22 AugTomorrow
22 Aug - 23 AugThis weekend
21 Aug - 23 AugNext weekend
28 Aug - 30 AugSave an average of 15% on thousands of hotels when you're signed in
Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Southern Indiana.

Galt House Hotel Trademark Collection by Wyndham
140 North Fourth Street Louisville KY
HK$1,121
HK$1,319 total
2 Sept - 3 Sept
includes taxes & fees
9/10 Wonderful! (4,270 reviews)

Omni Louisville Hotel
400 S. 2nd Street Louisville KY
HK$1,248
HK$1,469 total
23 Aug - 24 Aug
includes taxes & fees
9.4/10 Exceptional! (2,083 reviews)

Hyatt Regency Louisville
320 West Jefferson Street Louisville KY
HK$1,123
HK$1,321 total
23 Aug - 24 Aug
includes taxes & fees
8.8/10 Excellent! (1,011 reviews)
Still don't see what you're looking for?
See all properties in Southern Indiana.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Southern Indiana
Find lots to see and do in Southern Indiana—live music, sports teams and sights from Patoka Lake Swimming Beach to Patoka Lake.
See all hotels in Southern Indiana
Top Southern Indiana Hotel Reviews
Frequently asked questions
How much does it cost to stay in a 5-star hotel in Southern Indiana?
You'll find a range of pricing options for 5-star hotels in Southern Indiana on Expedia. How much you'll pay will depend on your travel dates, length of stay and other factors. Compare all of the available accommodation for your desired dates and make use of our pricing and other filters to score the perfect luxury stay.
- Search for the lowest price per night from HK$1,319
What makes a hotel 5 stars in Southern Indiana?
Exemplary guest service is at the heart of every 5-star hotel in Southern Indiana. From the instant you arrive, staff cater to your every whim, whether arranging valet parking or providing in-room massage treatments. Also, hotels have to offer superior amenities to be entitled to a 5-star rating. These can include deluxe baths, saunas or spas, pools, gourmet kitchens and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Southern Indiana?
Find an indulgent getaway that includes your lodging, meals, drinks and entertainment in Southern Indiana with Expedia's filter tool. Search for properties rated 5 stars and select the "All inclusive" filter. Be sure to check what's included in the price. That way, you can take full advantage of all the premium perks as soon as you arrive.