Lee County Holiday Rentals

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Our top choices for Lee County holiday rentals

Interior

Walking distance from one of South Carolina's top Medical centers.

Walking distance from one of South Carolina's top Medical centers.
Florence
9.8 out of 10, Exceptional, (45 reviews)
"Everything was great!"
United States
Debra B.
The price is HK$810
HK$1,520 total
includes taxes & fees
10 Mar - 11 Mar
Walking distance from one of South Carolina's top Medical centers.
TV

Cozy Blue Cottage 2BR/1BA

Cozy Blue Cottage 2BR/1BA
Hartsville
9.0 out of 10, Wonderful, (8 reviews)
"Enjoyed my time in Hartsville with family "
United States
Lori
The price is HK$860
HK$1,796 total
includes taxes & fees
9 Mar - 10 Mar
Cozy Blue Cottage 2BR/1BA
Fridge, microwave, oven, stovetop

Camden Cottage

Camden Cottage
Camden
10.0 out of 10, Exceptional, (59 reviews)
"Needs more stars! Perfect place to stay and owners are fabulous. Clean, spacious, quiet, and private. Its like home. I highly recommend!"
United States
Cass
The price is HK$774
HK$1,393 total
includes taxes & fees
15 Mar - 16 Mar
Camden Cottage
1 bedroom, WiFi, bed sheets

Historic Camden Showstopper!! THE LITTLE GARDNER’S COTTAGE

Historic Camden Showstopper!! THE LITTLE GARDNER’S COTTAGE
Camden
10.0 out of 10, Exceptional, (4 reviews)
"Cool loft! Convenient location, a drive will be in order to get downtown to the square. Quiet neighborhood."
United States
Taylor B.
The price is HK$767
HK$1,472 total
includes taxes & fees
9 Mar - 10 Mar
Historic Camden Showstopper!! THE LITTLE GARDNER’S COTTAGE
Fridge, microwave, oven, stovetop

Pear Tree Farm. Peaceful, Country living at its best. 12 stables. Pet Friendly

Pear Tree Farm. Peaceful, Country living at its best. 12 stables. Pet Friendly
Rembert
9.6 out of 10, Exceptional, (24 reviews)
"Would definitely stay here again! This property is very reasonably priced. Host was great in communication. It was just a lovely, peaceful, and safe place to stay! Wish we would have stayed longer! Thank you so very much."
United States
Josh M.
The price is HK$1,056
HK$2,041 total
includes taxes & fees
23 Mar - 24 Mar
Pear Tree Farm. Peaceful, Country living at its best. 12 stables. Pet Friendly
Dining

Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.

Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.
Florence
8.8 out of 10, Excellent, (3 reviews)
"Convenient location"
United States
Bonney W.
The price is HK$1,173
HK$3,951 total
includes taxes & fees
9 Mar - 10 Mar
Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.
Fridge, microwave, oven, stovetop

Creekside Country Cottage- minutes away from I-95

Creekside Country Cottage- minutes away from I-95
Manning
10.0 out of 10, Exceptional, (9 reviews)
"Great place beautiful and the dogs loved it"
United States
Jennifer T.
The price is HK$1,760
HK$3,378 total
includes taxes & fees
9 Mar - 10 Mar
Creekside Country Cottage- minutes away from I-95
Private kitchen

Charming 1-bedroom house with WiFi, AC in nice Sumter

Charming 1-bedroom house with WiFi, AC in nice Sumter
Sumter
The price is HK$1,173
HK$2,006 total
includes taxes & fees
14 Mar - 15 Mar
Charming 1-bedroom house with WiFi, AC in nice Sumter
2 bedrooms, WiFi, bed sheets

Lakeside 2-bedroom RV in charming Hartsville with AC, WiFi

Lakeside 2-bedroom RV in charming Hartsville with AC, WiFi
Hartsville
8.0 out of 10, Very good, (1 review)
"The stay was fine , with no problems."
United States
Mark H.
The price is HK$528
HK$1,172 total
includes taxes & fees
15 Mar - 16 Mar
Lakeside 2-bedroom RV in charming Hartsville with AC, WiFi
Interior

Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's

Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's
Florence
10.0 out of 10, Exceptional, (47 reviews)
"I would definitely stay again! Great location."
United States
LaDara D.
The price is HK$1,782
HK$2,267 total
includes taxes & fees
9 Mar - 10 Mar
Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's
Property grounds

Cozy 1-bedroom apartment at Greenleaf Villa. Downtown Camden, SC.

Cozy 1-bedroom apartment at Greenleaf Villa. Downtown Camden, SC.
Camden
8.0 out of 10, Very good, (1 review)
"we did not see or talk directly to the host; the amenities were all in good condition"
United States
George H.
The price is HK$696
HK$1,086 total
includes taxes & fees
5 Apr - 6 Apr
Cozy 1-bedroom apartment at Greenleaf Villa. Downtown Camden, SC.
Interior

Perfect Stop • Near I-95, Downtown & Civic Center and Darlington

Perfect Stop • Near I-95, Downtown & Civic Center and Darlington
Florence
9.8 out of 10, Exceptional, (6 reviews)
The price is HK$1,676
HK$2,113 total
includes taxes & fees
15 Mar - 16 Mar
Perfect Stop • Near I-95, Downtown & Civic Center and Darlington
Dining

The Farm House on Adams

The Farm House on Adams
Sumter
The price is HK$1,408
HK$2,795 total
includes taxes & fees
31 Mar - 1 Apr
The Farm House on Adams
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Lee County Hotel Reviews

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

8/10 Good
"At 8am breakfast was missing many items. Oatmeal low and no sugar or cinnamon etc. no yogurt. Granted it was a full hotel but planning for capacity seemed amiss. "
Sandra 1-night trip
Posted 7 hours ago
Comfort Inn & Suites Florence Center Area