Florence Mcleod Regional Medical Center Hotels: 2026 Limited-Time Hotel Deals @Expedia

A modern building with a curved glass facade, surrounded by a well-maintained lawn and several trees.

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Our top choices for Mcleod Regional Medical Center hotels

A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.

A multi-story hotel with a modern facade, featuring a prominent 'Hyatt Place' sign on the right.

A modern lounge area with brick walls, large windows, and contemporary furniture.

A modern bar area with a long counter, bar stools, and a variety of bottles and glasses.

1. Hyatt Place Florence Downtown

0.7 km from Mcleod Regional Medical Center

Evan

HK$863

HK$966 total

includes taxes & fees

1 Oct - 2 Oct

A restaurant with brick walls, framed awards, and a bar area.

An outdoor patio area with a brick wall, a covered seating area with string lights, and potted plants.

A bar area with a curved counter, multiple stools, and a brick wall backdrop.

A spacious kitchen with a dining area, a living room with a fireplace, and a cozy seating arrangement.

2. Hotel Florence, Tapestry Collection by Hilton

0.8 km from Mcleod Regional Medical Center

Ankh

HK$987

HK$1,106 total

includes taxes & fees

24 Sept - 25 Sept

3. Rodeway Inn Florence Downtown

1.2 km from Mcleod Regional Medical Center

HK$333

HK$385 total

includes taxes & fees

11 Oct - 12 Oct

A modern kitchen with stainless steel appliances, a gray sofa, and a ceiling fan.

A modern kitchen with a built-in dishwasher, a large island with a sink, pendant lights, and a ceiling fan.

A modern living room with a grey sofa, a round coffee table, a grey armchair with patterned cushions, a floor lamp, and a large TV mounted on the wall.

A modern kitchen with grey cabinets, stainless steel appliances, and bar stools.

4. The Urban Flats

0.8 km from Mcleod Regional Medical Center

HK$2,243

HK$3,688 total

includes taxes & fees

14 Sept - 15 Sept

A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.

A modern hotel with a 'Park Inn by Radisson' sign, featuring a covered entrance, multiple windows, and a parking lot.

A modern kitchen with a patterned backsplash, wooden cabinets, and stainless steel appliances.

A hotel room with a large bed, a desk with a lamp, a chair, a TV, and a window with curtains.

5. Park Inn by Radisson Florence, SC

5.5 km from Mcleod Regional Medical Center

Hector

HK$700

HK$784 total

includes taxes & fees

20 Sept - 21 Sept

A spacious lobby with a checkered floor, a reception desk, and a chandelier.

A two-story building with a brick facade, a flat roof, and a covered entrance area.

A vending area with snack and drink options, including Pepsi refrigerators and a 'MARKET' display with various products.

A spacious dining area with multiple tables and chairs, large windows offering a view of the parking lot, and a television mounted on the wall.

6. Howard Johnson by Wyndham Florence

5.5 km from Mcleod Regional Medical Center

HOMERO

HK$507

HK$567 total

includes taxes & fees

13 Sept - 14 Sept

A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.

An indoor swimming pool with clear water, surrounded by a checkered wall pattern, and equipped with multiple seating areas and a lifeguard station.

A lobby with leather sofas, a coffee table, potted plants, and a reception desk.

A corridor with shelves stocked with snacks and a frozen food display.

7. Hampton Inn & Suites Florence-North-I-95

5.7 km from Mcleod Regional Medical Center

Michelle

HK$926

HK$1,037 total

includes taxes & fees

17 Sept - 18 Sept

A hotel room with two beds, a desk with a TV, and a bathroom visible through an open door.

A large, two-story building with a central entrance flanked by columns, labeled "DIR FRANK B. LEE NURSING BUILDING."

A swimming pool with lounge chairs and a view of the outdoors.

A hotel lobby with a seating area, a coffee station, and a TV mounted on the wall.

8. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

9.1 km from Mcleod Regional Medical Center

Christopher

HK$925

HK$1,114 total

includes taxes & fees

13 Sept - 14 Sept

A hotel lobby with a reception desk, seating area, and a television screen.

A spacious dining area with multiple tables and chairs, large windows, and a flat-screen TV mounted on the wall.

A hotel room with a sectional sofa, two ottomans, a bed with a green bedspread, and framed pictures on the wall.

A hotel room with a bed, a sofa, an ottoman, and a lamp.

9. Comfort Inn & Suites Florence Center Area

7 km from Mcleod Regional Medical Center

Mike

HK$823

HK$922 total

includes taxes & fees

4 Oct - 5 Oct

An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.

A modern hotel restaurant with a breakfast bar, seating area, and a view of the city.

A modern lounge area with seating, tables, and a pool table.

A modern hotel with a prominent 'TRU by Hilton' sign, a well-lit entrance, and a landscaped front yard.

10. Tru by Hilton Florence I-95

5.9 km from Mcleod Regional Medical Center

Tiffany

HK$765

HK$904 total

includes taxes & fees

17 Sept - 18 Sept

A hotel entrance with a stone facade, glass doors, and a number '501' above.

A modern living room with a stone fireplace, a blue sofa, a brown leather chair, and a round coffee table.

A corner market with shelves stocked with snacks and beverages, and two large refrigerators.

A hotel reception area with a wooden floor, a reception desk, a seating area with chairs, and a decorative wall with a tree pattern.

11. Fairfield Inn & Suites by Marriott Florence I-20

6.9 km from Mcleod Regional Medical Center

leslie

HK$993

HK$1,112 total

includes taxes & fees

17 Sept - 18 Sept

A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.

A modern lounge area with a sofa, armchairs, and small tables.

A self-service beverage station with refrigerated and non-refrigerated drink options, snack shelves, and a sign indicating the location.

A modern kitchen with a coffee station, a dining area with a table and chairs, and a living area with a sofa and a coffee table.

12. TownePlace Suites by Marriott Florence

7 km from Mcleod Regional Medical Center

William

HK$893

HK$1,000 total

includes taxes & fees

13 Sept - 14 Sept

A building with two red doors, one labeled 'Office' and the other '101'. There is a welcome sign and a mailbox on the wall.

A house with a stone-paved entrance, a bench, and two red doors labeled "OFFICE" and "PRIVATE."

A room with a sofa, a small table, a chair, a lamp, and a door.

A compact kitchen with a dining area, a TV, and a small table.

13. Affordable Suites Florence

7 km from Mcleod Regional Medical Center

Cheyenne

HK$543

HK$609 total

includes taxes & fees

5 Oct - 6 Oct

A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.

A Country Inn & Suites by Radisson building with a parking lot and palm trees.

An outdoor patio with a wooden table and wicker chairs, a barbecue grill, and a swimming pool in the background.

A hotel room with two beds, a desk with a chair, a television, and a window with curtains.

14. Spark by Hilton Florence North I-95, SC

5.5 km from Mcleod Regional Medical Center

Michelle

HK$637

HK$744 total

includes taxes & fees

4 Oct - 5 Oct

A spacious lobby with a high ceiling, a central seating area with armchairs and a coffee table, a flat-screen TV, and a dining area with tables and chairs.

A modern hotel lobby with a fireplace, seating area, and a reception desk.

A modern hotel lobby with a central seating area, a large abstract painting, and a patterned carpet.

A hotel with a modern design, featuring multiple floors and a parking lot.

15. Residence Inn Marriott Florence

7.2 km from Mcleod Regional Medical Center

TERRENCE

HK$903

HK$1,012 total

includes taxes & fees

4 Oct - 5 Oct

A spacious lobby with a reception desk, seating area, and large windows.

A reception area with a counter, a sign for 'The Pavilion Pantry', and a green wall.

An indoor swimming pool with clear poolside areas, a lifeguard station, and a view of the outside.

A Hilton Garden Inn with a large, multi-story building, a covered entrance, and a parking lot.

16. Hilton Garden Inn Florence

7.2 km from Mcleod Regional Medical Center

Derrick

HK$894

HK$1,001 total

includes taxes & fees

27 Sept - 28 Sept

A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.

A lobby with a fireplace, seating area, and a television.

A Hampton Inn & Suites with a large sign, brick facade, and a parking lot.

A hotel lobby with a reception desk, seating area, and a welcome mat.

17. Hampton Inn & Suites Florence Center

7.2 km from Mcleod Regional Medical Center

Jennifer

HK$868

HK$973 total

includes taxes & fees

27 Sept - 28 Sept

A hotel room with a large bed, a desk with a chair, a television, and a walk-in closet.

A modern restaurant with red upholstered chairs, a flat-screen TV mounted on the wall, and a ceiling with recessed lighting.

An outdoor patio area with lounge chairs and tables, a brick building, and a clear sky.

A coffee station with two coffee machines and a display of coffee pods and cups.

18. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

8 km from Mcleod Regional Medical Center

Leigh

HK$933

HK$1,045 total

includes taxes & fees

11 Oct - 12 Oct

A hotel room with a desk, a bed, a sofa, a TV, and a mirror.

A swimming pool with lounge chairs and a building with balconies.

A hotel dining area with wooden tables and chairs, a fireplace, and a television.

A swimming pool with a metal ladder, lounge chairs, and a building with balconies.

19. Quality Inn & Suites Florence Civic Center

7.5 km from Mcleod Regional Medical Center

Noémie

HK$699

HK$783 total

includes taxes & fees

20 Sept - 21 Sept

A modern lobby with seating areas, a reception desk, and a large wall with a decorative panel.

A hotel room with a bed, a blue sofa, a brown ottoman, a black office chair, a desk, a lamp, and three framed pictures on the wall.

A Comfort Suites hotel with a modern design, featuring a prominent entrance with columns, a covered walkway, and a clear blue sky.

A modern coffee station with a counter, coffee machines, and a seating area with chairs.

20. Comfort Suites Florence I-95

5.9 km from Mcleod Regional Medical Center

Denise

HK$685

HK$799 total

includes taxes & fees

4 Oct - 5 Oct

View all properties

Top Mcleod Regional Medical Center Hotel Reviews

Park Inn by Radisson Florence, SC

8/10 Good

"Breakfast and coffee need improvement."

Spark by Hilton Florence North I-95, SC

10/10 Excellent

"Good value for quick stop on Florence, SC"

Howard Johnson by Wyndham Florence

10/10 Excellent

"Clean and well kept. Handicap room 107 just needs grab bar in the shower/bathtub area. We will definitely stay here again 😀"

Super 8 by Wyndham Florence

10/10 Excellent

"Room was very comfortable and is one of the best Super 8 properties I’ve ever been in. Teresa the Manager is the best. Definitely recommend this place if you’re in Florence SC"

Microtel Inn & Suites by Wyndham Florence

10/10 Excellent

"Clean room"

Best Western Inn

10/10 Excellent

"Clean location and excellent service."

SpringHill Suites by Marriott Florence

10/10 Excellent

"All very good"

Hotel Florence, Tapestry Collection by Hilton

10/10 Excellent

"The hotel was beautiful. It was quaint and it had two different bars. One was a guitar bar where you could have appetizers and drink and the other was a four-star restaurant that was absolutely awesome. We ate there each night and had a totally different meal each night. The bartenders were friendly and the atmosphere was light and fun. We felt very welcome and happy."

Come Stay A While

10/10 Excellent

"Loved the in unit washer and dryer. The house was visibly clean and smelled clean. Plenty of towels. The kitchen had cutting boards and pots and pans. Very comfortable and nice neighborhood. Host was very responsive."

Frequently asked questions

What's the area like around Mcleod Regional Medical Center?

Mcleod Regional Medical Center is located in a welcoming area of Florence known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 16 hotels and other accommodation options you'll find within a mile.

What's the best place to stay near Mcleod Regional Medical Center?

Hyatt Place Florence Downtown is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a restaurant. It's located just a short 0.4 mi (0.7 km) from Mcleod Regional Medical Center. Other good options within a short distance include Hotel Florence, Tapestry Collection by Hilton and The Urban Flats.

How many hotels can I expect to find near Mcleod Regional Medical Center?

Expedia has 16 hotels and other accommodation options within a mile from Mcleod Regional Medical Center.

If I need to cancel the hotel reservation for my stay near Mcleod Regional Medical Center, will I receive a refund?

Yes! You'll find that most hotel reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view top deals close to Mcleod Regional Medical Center.

What can I see and do near Mcleod Regional Medical Center?

You can enjoy live performances at FMU Performing Arts Center and Florence Little Theatre. You might spend a leisurely day outdoors at Florence Veterans Park and Greenwood Baseball Park and Playground. Create some family memories at Sky Zone Trampoline Park and Tilt Studio.

Florence Mcleod Regional Medical Center Hotels

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for Mcleod Regional Medical Center hotels

1. Hyatt Place Florence Downtown

2. Hotel Florence, Tapestry Collection by Hilton

3. Rodeway Inn Florence Downtown

4. The Urban Flats

5. Park Inn by Radisson Florence, SC

6. Howard Johnson by Wyndham Florence

7. Hampton Inn & Suites Florence-North-I-95

8. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

9. Comfort Inn & Suites Florence Center Area

10. Tru by Hilton Florence I-95

11. Fairfield Inn & Suites by Marriott Florence I-20

12. TownePlace Suites by Marriott Florence

13. Affordable Suites Florence

14. Spark by Hilton Florence North I-95, SC

15. Residence Inn Marriott Florence

16. Hilton Garden Inn Florence

17. Hampton Inn & Suites Florence Center

18. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

19. Quality Inn & Suites Florence Civic Center

20. Comfort Suites Florence I-95

Top Mcleod Regional Medical Center Hotel Reviews

Park Inn by Radisson Florence, SC

Spark by Hilton Florence North I-95, SC

Howard Johnson by Wyndham Florence

Super 8 by Wyndham Florence

Microtel Inn & Suites by Wyndham Florence

Best Western Inn

SpringHill Suites by Marriott Florence

Hotel Florence, Tapestry Collection by Hilton

Come Stay A While

Frequently asked questions

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