Santa Cruz hotels from HK$193
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Santa Cruz
Pet friendly
Apartment
Condo
Family friendly
Waterpark
Check prices for these dates
Tonight
13 Sept - 14 SeptTomorrow
14 Sept - 15 SeptNext weekend
18 Sept - 20 SeptIn two weeks
25 Sept - 27 SeptOur top choices for Santa Cruz hotels
1. Hotel LP Equipetrol
Hotel LP EquipetrolEquipetrol
Ricardo
HK$345
HK$385 total
30 Sept - 1 Oct
2. Ibis Santa Cruz DE LA Sierra
Ibis Santa Cruz DE LA SierraEquipetrol
Hui Hua
HK$356
HK$356 total
2 Oct - 3 Oct
3. Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio HotelEquipetrol
ERNESTO
HK$1,127
HK$1,127 total
1 Oct - 2 Oct
5. Camino Real Hotel
Camino Real HotelSanta Cruz
Wendy
HK$1,264
HK$1,264 total
6 Oct - 7 Oct
6. Hotel Las Américas
Hotel Las AméricasCentro Histórico
Stanley
HK$205
HK$205 total
15 Sept - 16 Sept
7. Premium Suites Deluxe Aparthotel Equipetrol
Premium Suites Deluxe Aparthotel EquipetrolSanta Cruz
Luisa
HK$361
HK$361 total
15 Sept - 16 Sept
8. Delfines Collection Hotel By Mercure
Delfines Collection Hotel By MercureEquipetrol
Mathetes
HK$431
HK$431 total
1 Oct - 2 Oct
9. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Hampton by Hilton Santa Cruz/Equipetrol, BoliviaSanta Cruz
Scott
HK$577
HK$577 total
2 Oct - 3 Oct
11. Marriott Santa Cruz de la Sierra Hotel
Marriott Santa Cruz de la Sierra HotelSanta Cruz
Deivis
HK$830
HK$830 total
2 Oct - 3 Oct
13. TRYP by Wyndham Santa Cruz
TRYP by Wyndham Santa CruzEquipetrol
Pluetina
HK$684
HK$684 total
15 Sept - 16 Sept
15. Hotel LP Santa Cruz Centro
Hotel LP Santa Cruz CentroSanta Cruz
John
HK$388
HK$427 total
30 Sept - 1 Oct
16. Hotel Pascana centro
Hotel Pascana centroCentro Histórico
HK$407
HK$407 total
15 Sept - 16 Sept
17. Novotel Santa Cruz De La Sierra
Novotel Santa Cruz De La SierraSanta Cruz
ERNESTO
HK$969
HK$969 total
1 Oct - 2 Oct
19. Swissôtel Santa Cruz De La Sierra
Swissôtel Santa Cruz De La SierraSanta Cruz
GONZALO
HK$1,029
HK$1,029 total
3 Oct - 4 Oct
20. Cosmopolitano Hotel Boutique
Cosmopolitano Hotel BoutiqueCentro Histórico
Veronica
HK$451
HK$451 total
28 Sept - 29 Sept
Holiday Rentals in Santa Cruz
Aparthotel
Premium Suites Deluxe Aparthotel Equipetrol
Premium Suites Deluxe Aparthotel EquipetrolSanta Cruz
"great place to stay!"
Apartment
Apart Hotel Premium Suites Santa Cruz
Apart Hotel Premium Suites Santa CruzSanta Cruz
"Great location."
Aparthotel
Apart Hotel Toborochi
Apart Hotel ToborochiEquipetrol
"Very comfortable and quiet place and very good location. "
Save an average of 15% on thousands of hotels when you're signed in
Where to stay in Santa Cruz
Find the best Santa Cruz areas for the activities you enjoy most.Learn more about Santa Cruz
Learn more about Santa Cruz
Hamacas
When in Hamacas, you can plan a visit to Santa Cruz Zoo and Las Brisas Shopping Center, some noteworthy sights in the nearby area.
Centro Histórico
If you're spending some time in Centro Histórico, Plaza 24 de Septiembre and La Recova Artisan Walk are top sights worth seeing.
Urubó
While there might not be top attractions in Urubó, you can explore the larger area and discover places like Guembe Biocenter and Ventura Mall.
Zona Sur (South Zone)
Though Zona Sur (South Zone) may not have many top sights, you can venture to the surrounding area to see attractions like Blacutt Square and Ramon Tahuichi Aguilera Stadium.
Equipetrol
When in Equipetrol, you can plan a visit to Santa Cruz Zoo and Ventura Mall, some noteworthy sights in the nearby area.
Stay near popular Santa Cruz attractions
Plaza 24 de Septiembre
8.8/10 (164 reviews)
Plaza 24 de Septiembre buzzes with local culture beneath swaying palms and colonial architecture. Climb the Cathedral's bell tower for spectacular city views while sampling authentic Bolivian coffee from vendors.
San Lorenzo Cathedral
9.0/10 (84 reviews)
This grand neoclassical cathedral dominates Santa Cruz's skyline with its towering spires and ornate façade. Climb the bell tower at sunset for breathtaking panoramic views of the city.
Ventura Mall
9.0/10 (183 reviews)
Ventura Mall, Santa Cruz's premier shopping destination, features international brands and local boutiques. Enjoy the cinema complex, food court, and entertainment options in this contemporary Bolivian retail hub.
Guembe Biocenter
8.8/10 (60 reviews)
This vibrant ecological sanctuary showcases hundreds of butterfly species in a lush, tropical environment. Explore walking trails, enjoy boat rides, and learn about biodiversity in this serene natural retreat.
Santa Cruz Zoo
8.4/10 (53 reviews)
The Santa Cruz Municipal Zoo showcases Bolivia's native wildlife in naturalistic habitats, featuring jaguars, tapirs, and free-ranging sloths. Morning visits offer the best chance to see active animals.
Ramon Tahuichi Aguilera Stadium
8.4/10 (18 reviews)
This multi-purpose stadium hosts Bolivia's most passionate football rivalries and tournaments. Experience the electric atmosphere of a local derby while enjoying modernised facilities and vibrant Santa Cruz culture.
Blacutt Square
8.2/10 (19 reviews)
Plaza Blacutt offers a verdant escape in Santa Cruz with mature trees shading tiled pathways. Enjoy local flavours from vendors along the northern edge while children play in the well-equipped playground areas.
Cine Center
8.0/10 (53 reviews)
This premier entertainment complex offers state-of-the-art cinema experiences with immersive 4D E-Motion formats. Enjoy the latest films, then explore the shopping centre and diverse dining options in the food court.
Learn more about Santa Cruz
Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.
See all hotels in Santa Cruz
Top Santa Cruz Hotel Reviews
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
10/10 Excellent
"Very nice place to stay and enjoy the climate in Santa Cruz. Many amenities and friendly staff."
Hotel Cortez
10/10 Excellent
"Awesome Hotel"
Sun Hotel
10/10 Excellent
"Very nice place to stay. Close to the airport with shuttle to the hotel."
TRYP by Wyndham Santa Cruz
10/10 Excellent
"We had a great stay here. The rooms were clean and comfortable. Will return!"
Camino Real Hotel
10/10 Excellent
"The food is excellent quality and delicious! Friendly staff"
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
10/10 Excellent
"The room was very clean and the breakfast was fantastic. Overall it was a great experience."
Hotel Las Américas
10/10 Excellent
"DELICIOSO EL DESAYUNO"
Novotel Santa Cruz De La Sierra
10/10 Excellent
"All around good price and location"
HOTEL OSHO
10/10 Excellent
"Good"
More cheap stays in Santa Cruz
Equipetrol Suites Apart Hotel
Equipetrol Santa Cruz Departamento de Santa Cruz
HK$403
HK$403 total
15 Sept - 16 Sept
Casa Por Temporadas
Barrio Las Pampitas, calle 3 Nro. 99 Santa Cruz Santa Cruz Department
10/10 Exceptional! (1 review)
HOTEL CASA BLANCA
Avenida Marcelo Terceros Zona Equipetrol Santa Cruz Santa Cruz de la Sierra
Hotel Viru Viru II
Av. Alameda 72 - Zona Valle Sanchez Santa Cruz Santa Cruz de la Sierra
4.8/10 (3 reviews)
