Santa Cruz Holiday Rentals

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
27 Mar - 29 Mar
In two months
8 May - 10 May
In three months
5 Jun - 7 Jun
In four months
3 Jul - 5 Jul

Our top choices for Santa Cruz holiday rentals

1 bedroom, premium bedding, down duvets, free WiFi

Shabbat Hotel Boutique

Shabbat Hotel Boutique
4.0 star property
San Vicente
10.0 out of 10, Exceptional, (2 reviews)
"Excelente Servicio y facilidades. 100% recomendado"
United States
william
Shabbat Hotel Boutique
Mountain view

Sky View Glamping

Sky View Glamping
2.0 star property
Girardota
9.0 out of 10, Wonderful, (2 reviews)
"Great view and the hospitality was very good.. The cabins were clean. "
United States
Chris
The price is HK$844
HK$844 total
17 Mar - 18 Mar
Sky View Glamping
Minibar, individually decorated, individually furnished, free WiFi

Wasikuna cabañas rurales tipo glamping

Wasikuna cabañas rurales tipo glamping
3.0 star property
Guarne
10.0 out of 10, Exceptional, (4 reviews)
"Nice place "
United States
GERARDO
Wasikuna cabañas rurales tipo glamping
Minibar, desk, laptop workspace, blackout curtains

Mali Experience

Mali Experience
3.0 star property
Rionegro
10.0 out of 10, Exceptional, (1 review)
"Espectacular apartamento y el sitio es muy bueno"
Colombia
Giovanni
The price is HK$536
HK$536 total
19 Mar - 20 Mar
Mali Experience
Living area

Skyline Ecoliving

Skyline Ecoliving
3.0 star property
El Rosario
9.2 out of 10, Wonderful, (40 reviews)
"Best views ever! The staff was always amazing, and it was the perfect spot to escape the city noise for a little while."
United States
Andres
Skyline Ecoliving
Outdoor pool

PORTANOVA SUITES by ADVENTU

PORTANOVA SUITES by ADVENTU
3.0 star property
Rionegro
8.6 out of 10, Excellent, (46 reviews)
"Room was very clean and apt is very quiet and close to the hospital "
United States
FERNANDO
PORTANOVA SUITES by ADVENTU
Exterior

Aparta Suite Rioverde Hotel Rioverde Airport JMC

Aparta Suite Rioverde Hotel Rioverde Airport JMC
Rionegro
10.0 out of 10, Exceptional, (1 review)
The price is HK$599
HK$833 total
16 Mar - 17 Mar
Aparta Suite Rioverde Hotel Rioverde Airport JMC
View from room

Travelers Rio Verde Living Suites

Travelers Rio Verde Living Suites
3.5 star property
Rionegro
8.4 out of 10, Very good, (471 reviews)
"GOOD PLACE TO STAY THE NIGHT NEAR THE AIRPORT"
United States
Robert
Travelers Rio Verde Living Suites
Outdoor dining

Almaia 17

Almaia 17
3.0 star property
Rionegro
The price is HK$1,056
HK$3,210 total
13 Mar - 14 Mar
Almaia 17
Desk, laptop workspace, blackout curtains, soundproofing

Edificio Cielo Verde

Edificio Cielo Verde
3.0 star property
Rionegro
The price is HK$1,098
HK$1,309 total
17 Mar - 18 Mar
Edificio Cielo Verde
Exterior

Candelaria Campestre

Candelaria Campestre
2.0 star property
El Carmen de Viboral
The price is HK$585
HK$775 total
22 Mar - 23 Mar
Candelaria Campestre
Front of property

Hotel Rioverde- 5 minutos de cercanía al aeropuerto

Hotel Rioverde- 5 minutos de cercanía al aeropuerto
4.5 star property
Rionegro
7.6 out of 10, Good, (59 reviews)
"Clean room and good amenities. Close to the airport which was useful after a long flight "
Australia
DAVID
Hotel Rioverde- 5 minutos de cercanía al aeropuerto
Premium bedding, down duvets, minibar, free WiFi

Hotel Moore 45

Hotel Moore 45
4.0 star property
Buenos Aires
8.0 out of 10, Very good, (1 review)
The price is HK$188
HK$188 total
15 Mar - 16 Mar
Hotel Moore 45
15 outdoor pools

Llano Grande

Llano Grande
3.5 star property
Rionegro
Llano Grande
Room

Onirico Luxury

Onirico Luxury
2.0 star property
Medellin
The price is HK$665
HK$665 total
16 Mar - 17 Mar
Onirico Luxury
Front of property

Nomadic Suites

Nomadic Suites
3.5 star property
El Poblado
9.6 out of 10, Exceptional, (4 reviews)
"Hotel nuevo, excelentes instalaciones, limpieza impecable, solo un detalle, solicité habitación para 4 personas y tenía una cama queen y sofá cama, solo que el sofá cama era algo incómodo para descanzar, de lo demás estuvo excelente."
Mexico
Moisés
The price is HK$675
HK$886 total
30 Mar - 31 Mar
Nomadic Suites
Private spa tub

Haven, A Design Hotel

Haven, A Design Hotel
4.0 star property
El Poblado
8.8 out of 10, Excellent, (667 reviews)
"Was reallly good excellent locations"
United States
Alvaro
The price is HK$728
HK$728 total
17 Mar - 18 Mar
Haven, A Design Hotel
Free WiFi, bed sheets

PILARICA GARDENS

PILARICA GARDENS
3.0 star property
Robledo
8.2 out of 10, Very good, (10 reviews)
"Overall it was adequate for me and suited my needs."
United States
Wayne
The price is HK$161
HK$161 total
17 Mar - 18 Mar
PILARICA GARDENS
Full-sized fridge, microwave, oven, stovetop

Luxury Suites Prana By Cadissa

Luxury Suites Prana By Cadissa
5.0 star property
Laureles - Estadio
9.2 out of 10, Wonderful, (38 reviews)
"We liked the comfort and the quiet neighbourhood, excellent staff and very knowledgeable and helpful. Beautiful place, will definitely stay there again."
United Kingdom
Eduardo Hernandez
Luxury Suites Prana By Cadissa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Santa Cruz Hotel Reviews

Calle Flora Hotel by Jalo

Calle Flora Hotel by Jalo

10/10 Excellent
"Staff was attentive, rooms were clean. Hot tub working well. It is right across the night life in Poblado so be aware of the music at night but otherwise it was a good hotel I would recommend to others! "
Lizvette 4-night trip
Posted 10 hours ago
Calle Flora Hotel by Jalo

Find out more about Santa Cruz

Search for holiday rentals in Santa Cruz on Expedia! You can easily find your home rentals, villas, holiday apartments in Santa Cruz using one of the methods below:

  • View our selection of featured holiday rentals in Santa Cruz
  • Use the map to find apartments and other holiday homes in the Santa Cruz neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Santa Cruz while they last

Look no further and take a look at our great range of rental properties in Santa Cruz!

Frequently asked questions

Can I find a holiday rental in Santa Cruz?

Yes, there are holiday rentals close to the most popular sights in Santa Cruz, or you can select a more secluded option if you're looking for a relaxing stay.

What are some of the best holiday rentals that Santa Cruz has to offer?

8 BR Luxury 6000 S.F. Mansion , 2 Bars Hot Tub, Bbq and Ac : This holiday home rental outside of Santa Cruz offers a patio, a pool table and a BBQ to help you feel perfectly comfortable in your new surroundings. It has 8 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. You and your friends and family can relax into your holiday with amenities such as 1 hot tub.

What’s there to see and do in Santa Cruz?

While exploring the area, visit family-friendly sights like Pueblito Paisa, or get outside and enjoy nature at Medellin Botanical Garden. In the wider area, you’ll find Parque Fabricato Shopping Center and University of Antioquia.

What’s a holiday rental in Santa Cruz like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Santa Cruz. Holiday rentals offer extras like WiFi and washers and dryers so you'll feel right at home. If you're concerned about a clean environment, holiday rentals can offer a sense of safety away from public hotel lifts and lobbies bustling with people while still allowing you the enjoyment of travel. You'll also find more space in a holiday rental than in a standard hotel, which is another reason why a holiday rental is a popular option for families.