Photo by Piccolo Lorenzo
Santa Lucia hotels in Syracuse
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Check prices for these dates
Our top choices for Santa Lucia hotels

9.4 out of 10, Exceptional, (257)
The price is HK$834
HK$1,009 total
includes taxes & fees
11 Jan - 12 Jan 2026

8.8 out of 10, Excellent, (57)
The price is HK$2,088
HK$2,389 total
includes taxes & fees
6 Jan - 7 Jan 2026

Fortaleza Charme House
Fortaleza Charme HouseSanta Lucia
10.0 out of 10, Exceptional, (27)
The price is HK$1,314
HK$1,497 total
includes taxes & fees
5 Jan - 6 Jan 2026
The price is HK$1,817
HK$2,072 total
includes taxes & fees
4 Jan - 5 Jan 2026
The price is HK$699
HK$797 total
includes taxes & fees
2 Jan - 3 Jan 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Santa Lucia
Find the best Santa Lucia areas for the activities you enjoy most.

Ortigia
Ortigia is popular for its seaside views, and if you're looking for more to see and do, you might think about a trip to Cathedral of Syracuse or Piazza del Duomo.
Tiche
Gardens and restaurants are notable features of Tiche. You might consider stopping by Ionian Sea while you're exploring the neighbourhood.
Grottasanta
Grottasanta is noteworthy for its historical sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.
Acradina
You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.
Neapolis
While visiting Neapolis, you might make a stop by sights like Roman Amphitheatre of Syracuse and Archaeological Park of Neapolis.
Top Santa Lucia Hotel Reviews

Grand Hotel Ortigia Siracusa
10/10 Excellent

























































































