Santee Holiday Rentals

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Our top choices for Santee holiday rentals

10.0 out of 10, Exceptional, (37)
"Great house, very modern interior. Very clean. Close to town. We’ll definitely book the house on our fishing trip. "
United States
John H.
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
8.4 out of 10, Very good, (6)
"Great property the pool was so fun! Mostly stayed on the property and lounged around for a nice relaxing stay!"
United States
Tori P.
The price is HK$692
HK$1,545 total
includes taxes & fees
3 Jan - 4 Jan 2026
Tranquil Getaways W/Heated Pool and Fishing
10.0 out of 10, Exceptional, (11)
"Nice place great location "
United States
Jeffrey H.
The price is HK$1,362
HK$3,412 total
includes taxes & fees
12 Jan - 13 Jan 2026
Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!
10.0 out of 10, Exceptional, (40)
"Great stay."
United States
Tim E.
The price is HK$739
HK$1,648 total
includes taxes & fees
3 Jan - 4 Jan 2026
Country living lake style near Santee
9.4 out of 10, Exceptional, (21)
"Great place for our family to stop on our way to Florida. It had ample parking, pet friendly, and very comfortable country retreat! "
United States
Jackie M.
The price is HK$933
HK$1,398 total
includes taxes & fees
4 Jan - 5 Jan 2026
Country Resting Spot just off I95. 12 miles west on hwy 6.

Mobile Home in Summerton

Hobbs Haven at Lake Marion
9.4 out of 10, Exceptional, (11)
"Everything was great!"
United States
James B.
The price is HK$894
HK$2,761 total
includes taxes & fees
3 Jan - 4 Jan 2026
Hobbs Haven at Lake Marion

Aparthotel in Eutawville

Bells Marina & Resort
2.5 star property
8.6 out of 10, Excellent, (82)
"Room was clean with a beautiful view of the Lake."
United States
Melanie
The price is HK$751
HK$833 total
includes taxes & fees
7 Jan - 8 Jan 2026
Bells Marina & Resort
9.8 out of 10, Exceptional, (16)
"Great stay!! "
United States
Josh L.
The price is HK$644
HK$1,319 total
includes taxes & fees
5 Jan - 6 Jan 2026
Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6
9.8 out of 10, Exceptional, (32)
"Will stay again."
United States
Robert B.
Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301
10.0 out of 10, Exceptional, (124)
"Super cute little house. Super comfy beds and pretty views. "
United States
colleen j.
The price is HK$875
HK$1,609 total
includes taxes & fees
13 Jan - 14 Jan 2026
Pet friendly country cottage with large fenced-in yard & horses on property
7.8 out of 10, Good, (7)
"Great view, excellent communication with the owners, relaxing, peaceful. "
United States
Christie
The price is HK$661
HK$1,105 total
includes taxes & fees
7 Jan - 8 Jan 2026
Cabin at the lake in Rimini, SC
10.0 out of 10, Exceptional, (6)
"Excellent stay! We will definitely be staying here again! Love this place! "
United States
Jonathan H.
The price is HK$972
HK$1,251 total
includes taxes & fees
4 Jan - 5 Jan 2026
Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston
8.2 out of 10, Very good, (14)
"Wish bathroom was closer but jt"
United States
Sharon W.
The price is HK$595
HK$1,031 total
includes taxes & fees
2 Jan - 3 Jan 2026
Cozy Camping Cabin on Lake Marion near Congaree Nat Park

Cottage in Shad Moss village

Cypress Cottage - Cozy Lake Getaway
2.0 star property
The price is HK$786
HK$2,313 total
includes taxes & fees
1 Jan - 2 Jan 2026
Cypress Cottage - Cozy Lake Getaway
The price is HK$1,154
HK$2,421 total
includes taxes & fees
6 Jan - 7 Jan 2026
Charming 2-bedroom townhome with AC and WiFi in peaceful Summerton
8.6 out of 10, Excellent, (18)
"Group of us older guys went for a golf weekend at Santee. The house was great and we really enjoyed our stay."
United States
Chris D.
The price is HK$967
HK$3,654 total
includes taxes & fees
5 Jan - 6 Jan 2026
Sweet Marion - Dock + Boat Ramp + Hot Tub!
9.0 out of 10, Wonderful, (4)
"Nice and quiet property. It served us well for the weekend "
United States
Mick S.
The price is HK$1,154
HK$2,179 total
includes taxes & fees
1 Jan - 2 Jan 2026
Beautiful brick home w/ large porch and 3 bedrooms
6.8 out of 10, (5)
"Perfect place for a weekend fishing trip. Owner was responsive. Slept 6 easily. Only stayed one night but was a perfect fit"
United States
brandon h.
The price is HK$924
HK$3,230 total
includes taxes & fees
5 Jan - 6 Jan 2026
Reel Haven on the Water: Modern + Comfy Home!
The price is HK$958
HK$3,310 total
includes taxes & fees
1 Jan - 2 Jan 2026
Turtle Cove - Lake Living on Lake Marion
The price is HK$910
HK$1,866 total
includes taxes & fees
1 Jan - 2 Jan 2026
The Tee Vee Cove is the place to be located near great golfing, fishing and food
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santee Hotel Reviews

Find out more about Santee

Search for holiday rentals in Santee on Expedia! You can easily find your home rentals, villas, holiday apartments in Santee using one of the methods below:

  • View our selection of featured holiday rentals in Santee
  • Use the map to find apartments and other holiday homes in the Santee neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Santee while they last

Look no further and take a look at our great range of rental properties in Santee!

Frequently asked questions

Can I find holiday rentals in Santee?

Yes, there are holiday rentals close to the most popular sights in Santee, or you can select a more secluded option if you're looking for a relaxing stay. Tourists appreciate the top-notch restaurants and coffee shops in Santee. Make sure you have time to check out the golf courses and lake views during your trip.

What are some of the best holiday rentals that Santee has to offer?

Wyndham Vacation Resorts Lake Marion: This highly rated holiday home rental in Santee is equipped with an outdoor pool, free WiFi and cable TV to help you feel comfortable during your stay. Kitchen amenities include a full-sized fridge, a dishwasher and a stovetop. Another good choice for your trip to Santee is Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!.

How many holiday rentals are there in Santee?

Expedia has 9 holiday rentals for your stay in Santee.

What can I see and do in Santee?

While you're exploring the area, Lake Marion and Santee National Wildlife Refuge are a couple of picturesque spots to get outside and enjoy nature. Santee Cooper Country Club and Santee State Park are other places to visit while you're in town.

What are holiday rentals like in Santee?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in Santee. Holiday rentals feature amenities like kitchens and laundry facilities so your stay will be comfortable. If you're concerned about a sanitised environment, holiday rentals can provide a sense of security away from public hotel lifts and busy reception areas while still allowing you the enjoyment of travel. You'll also have more space in a holiday rental than in a standard hotel, which is another reason why a holiday rental is a great option for small groups.