Best Effingham Hotels in 2026 from HK$515 - Fully Refundable Options

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Our top choices for Effingham hotels

An outdoor patio area with tables and chairs, a brick wall, and a glass door leading to the interior.

A spacious living room with hardwood flooring, a staircase, and a large window.

A spacious dining area with multiple tables and chairs, wooden flooring, and a modern chandelier.

A spacious lobby with a grand staircase, plush seating, and a modern kitchen area.

1. The Inn at the Crossroads

Lake City

Paige

HK$774

HK$866 total

includes taxes & fees

3 Sept - 4 Sept

A Holiday Inn Express & Suites hotel with a clear entrance, a covered parking area, and a well-maintained exterior.

A swimming pool with lounge chairs and a view of the outside.

A hotel lobby with a reception desk, a seating area with green sofas, and a dining area with tables and chairs.

A gym with treadmills, elliptical machines, and free weights.

2. Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Florence

Christopher

HK$925

HK$1,114 total

includes taxes & fees

7 Sept - 8 Sept

A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.

A multi-story hotel with a modern facade, featuring a prominent 'Hyatt Place' sign on the right.

A modern bar area with a long counter, multiple bar stools, and a variety of bottles and glasses.

A modern lounge area with brick walls, large windows, and contemporary furniture.

3. Hyatt Place Florence Downtown

Florence

Evan

HK$784

HK$878 total

includes taxes & fees

9 Sept - 10 Sept

A hotel lobby with a reception desk, seating area, and a television screen.

A Comfort Inn & Suites hotel with a covered entrance, brick facade, and multiple windows.

A hotel room with a bed, a sofa, an ottoman, and a lamp.

A spacious dining area with multiple tables and chairs, large windows, and a flat-screen TV mounted on the wall.

4. Comfort Inn & Suites Florence Center Area

Florence

Mike

HK$847

HK$949 total

includes taxes & fees

27 Sept - 28 Sept

A hotel room with a bed, a desk, a green sofa, and a painting on the wall.

An indoor swimming pool with lounge chairs and exercise equipment.

A hotel room with a desk, a green armchair, a small purple ottoman, a bed with a white headboard, and a large window.

5. Home2 Suites by Hilton Florence, SC

Florence

saleh

HK$791

HK$917 total

includes taxes & fees

27 Sept - 28 Sept

A hotel room with two beds, a wooden headboard, a window with curtains, and a wall-mounted air conditioner.

A modern kitchen with a built-in coffee station, a refrigerator, and a seating area with a patterned rug.

A spacious lobby with a reception desk, a large window display, and a 'market' sign on the wall.

6. SpringHill Suites by Marriott Florence

Florence

HK$812

HK$956 total

includes taxes & fees

11 Sept - 12 Sept

A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.

A lobby with a fireplace, seating area, and a television.

A Hampton Inn & Suites with a large sign, brick facade, and a parking lot.

A hotel room with two beds, a desk, a TV, and a window with patterned curtains.

7. Hampton Inn & Suites Florence Center

Florence

Jennifer

HK$862

HK$965 total

includes taxes & fees

20 Sept - 21 Sept

A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.

A modern kitchen with a patterned backsplash, wooden cabinets, and stainless steel appliances.

A modern living room with a grey sofa, a flat-screen TV, geometric wall art, and a bookshelf with decorative items.

A hotel room with a large bed, a desk with a lamp, a chair, a TV, and a window with curtains.

8. Park Inn by Radisson Florence, SC

Florence

Hector

HK$626

HK$701 total

includes taxes & fees

7 Sept - 8 Sept

A hotel entrance with a stone facade, glass doors, and a number '501' above.

An indoor swimming pool with a tiled floor, a pool ladder, and lounge chairs.

A hotel reception area with a wooden floor, a reception desk, a seating area with chairs, and a decorative wall with a tree pattern.

A corner market with shelves stocked with snacks and beverages, and two large refrigerators.

9. Fairfield Inn & Suites by Marriott Florence I-20

Florence

leslie

HK$993

HK$1,112 total

includes taxes & fees

9 Sept - 10 Sept

A hotel with a covered entrance, a beige facade, and pink flowering trees.

A hotel lobby with a reception desk, a wall-mounted TV, a decorative wall piece, and a seating area with tables and chairs.

A living room with a sofa, a coffee table, a chair, and two framed floral paintings on the wall.

A breakfast buffet with multiple serving dishes and a coffee station by a window with a view of trees.

10. Quality Inn Mullins - Marion

Marion

Willie

HK$628

HK$685 total

includes taxes & fees

27 Sept - 28 Sept

A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.

A hotel with a modern architectural design, featuring a prominent entrance canopy and a sign indicating it is a Staybridge Suites hotel.

A swimming pool area with lounge chairs and umbrellas, surrounded by a white building with large windows.

A hotel lobby with a stone fireplace, recessed lighting, and a large plant.

11. Staybridge Suites Florence - Civic Center by IHG

Florence

Frederick

HK$1,059

HK$1,186 total

includes taxes & fees

13 Sept - 14 Sept

A hotel room with a large bed, a desk with a chair, a television, and a walk-in closet.

A Holiday Inn Express & Suites with a covered outdoor area, brick facade, and a parking lot.

An indoor swimming pool with clear water, marked depth indicators, and safety signs.

A modern conference room with red and grey furniture, a blue pillar, and a mounted television on the wall.

12. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Florence

Leigh

HK$988

HK$1,106 total

includes taxes & fees

30 Sept - 1 Oct

A spacious lobby with a checkered floor, a reception desk, and a chandelier.

A spacious dining area with multiple tables and chairs, large windows offering a view of the parking lot, and a television mounted on the wall.

A hotel room with two beds, a desk with a computer, a chair, and a bathroom with a mirror.

A vending area with snack and drink options, including Pepsi refrigerators and a 'MARKET' display with various products.

13. Howard Johnson by Wyndham Florence

Florence

HOMERO

HK$506

HK$567 total

includes taxes & fees

3 Sept - 4 Sept

A restaurant with brick walls, framed awards, and a bar area.

A bar area with a curved counter, multiple stools, and a brick wall backdrop.

A spacious living room with a wooden floor, a ceiling fan, and a dining area with a wooden table and chairs.

A spacious kitchen with a dining area, a living room with a fireplace, and a cozy seating arrangement.

14. Hotel Florence, Tapestry Collection by Hilton

Florence

Ankh

HK$1,086

HK$1,217 total

includes taxes & fees

20 Sept - 21 Sept

A modern lobby with seating areas, a reception desk, and a large wall with a decorative panel.

An outdoor patio area with tables and chairs, a barbecue grill, and a large window overlooking a fenced area.

A hotel room with a bed, a blue sofa, a brown ottoman, a black office chair, a desk, a lamp, and three framed pictures on the wall.

A modern coffee station with a counter, coffee machines, and a seating area with chairs.

15. Comfort Suites Florence I-95

Florence

Jennifer

HK$669

HK$781 total

includes taxes & fees

28 Sept - 29 Sept

An outdoor patio area with wicker furniture, a wooden pergola, and a barbecue setup.

A hotel with a sign reading "Homewood Suites Hilton" and a landscaped entrance area with a circular brick pathway and benches.

A modern kitchen with dark wood cabinets, a central island with a glass enclosure, and a white countertop.

A modern lounge area with a fireplace, comfortable seating, and a decorative wall.

16. Homewood Suites by Hilton Florence

Florence

tracy

HK$838

HK$1,017 total

includes taxes & fees

20 Sept - 21 Sept

A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.

A Hampton Inn & Suites hotel with a well-lit entrance, multiple floors, and a parking area.

An indoor swimming pool with clear water, surrounded by a checkered wall pattern, and equipped with multiple seating areas and a lifeguard station.

A corridor with shelves stocked with snacks and a frozen food display.

17. Hampton Inn & Suites Florence-North-I-95

Florence

Michelle

HK$926

HK$1,037 total

includes taxes & fees

9 Sept - 10 Sept

A hotel with a modern design, featuring a parking lot with several cars and a well-lit entrance.

A hotel room with a bed, a desk with a chair, a television, a lamp, and a window with curtains.

A hotel lobby with a reception desk, a TV screen, patterned sofas, and a glass coffee table.

A spacious dining area with a large granite table surrounded by wooden chairs, a reception desk, and a flat-screen TV mounted on the wall.

18. Best Western Executive Inn

Latta

Geovanny

HK$866

HK$944 total

includes taxes & fees

9 Sept - 10 Sept

A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.

A reception area with a wooden desk, a map on the wall, and a sign welcoming visitors to Florence, SC.

A modern kitchen with a coffee station, a dining area with a table and chairs, and a living area with a sofa and a coffee table.

A modern lounge area with a sofa, armchairs, and small tables.

19. TownePlace Suites by Marriott Florence

Florence

William

HK$893

HK$1,000 total

includes taxes & fees

10 Sept - 11 Sept

A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.

A modern cafeteria with long wooden tables, green chairs, and yellow accents.

An outdoor patio with a wooden table and wicker chairs, a barbecue grill, and a swimming pool in the background.

A hotel room with two beds, a desk with a chair, a television, and a window with curtains.

20. Spark by Hilton Florence North I-95, SC

Florence

Michelle

HK$733

HK$852 total

includes taxes & fees

13 Sept - 14 Sept

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Top Effingham Hotel Reviews

TownePlace Suites by Marriott Florence

10/10 Excellent

"Staff was accommodating and very nice. The room is very clean and quiet"

Comfort Inn & Suites Florence Center Area

8/10 Good

"Na"

Hyatt Place Florence Downtown

10/10 Excellent

"A wonderful place to stay with really good breakfast!!!"

The Inn at the Crossroads

10/10 Excellent

"Front desk staff exceptional."

Tru by Hilton Florence I-95

10/10 Excellent

"I"

Days Inn by Wyndham Florence Near Civic Center

8/10 Good

"Good"

Hampton Inn & Suites Florence Center

10/10 Excellent

"We really enjoyed our stay."

Comfort Suites Florence I-95

8/10 Good

"Nice hotel. Just disappointed that the inside pool water is too cold to swim in. I asked before I booked if the pool water was warm and was told yes but once again it was cold and couldn’t swim."

Microtel Inn & Suites by Wyndham Florence

10/10 Excellent

"Surprinigly nice for the price"

More cheap stays in Effingham

Days Inn by Wyndham Florence/I-95 North

2111 West Lucas St/I-95 Florence SC

HK$460

HK$515 total

16 Sept - 17 Sept

includes taxes & fees

6.6/10 (1,000 reviews)

Howard Johnson by Wyndham Florence

2038 W Lucas Street Florence SC

HK$506

HK$567 total

3 Sept - 4 Sept

includes taxes & fees

Park Inn by Radisson Florence, SC

1729 Mandeville Road Florence SC

HK$626

HK$701 total

7 Sept - 8 Sept

includes taxes & fees

Quality Inn & Suites Florence Civic Center

150 Dunbarton Dr Florence SC

HK$686

HK$769 total

1 Oct - 2 Oct

includes taxes & fees

8.4/10 Very good! (352 reviews)

Comfort Inn & Suites Florence Center Area

527 Woody Jones Blvd Florence SC

HK$847

HK$949 total

27 Sept - 28 Sept

includes taxes & fees

9/10 Wonderful! (1,360 reviews)

Hampton Inn & Suites Florence Center

3000 W Radio Dr Florence SC

HK$862

HK$965 total

20 Sept - 21 Sept

includes taxes & fees

9/10 Wonderful! (959 reviews)

Frequently asked questions

Where is the best place to stay in Effingham?

Quality Inn & Suites Florence Civic Center, located 10.5 mi (16.9 km) from the heart of Effingham, is a top choice for your stay, based on our traveller data. Other good options for your trip to the area are Howard Johnson by Wyndham Florence and Park Inn by Radisson Florence, SC. See all available top hotels, or vacation rentals in Effingham.

What are some of the best holiday rentals that Effingham has to offer?

Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's: This holiday home rental outside of Effingham offers a fireplace, a patio and air conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Make the most of garden in this rental home to help you unwind. See all vacation rentals in Effingham.

If I need to cancel my hotel reservation in Effingham, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Effingham.

What's it like to stay in Effingham?

Travellers to Effingham will find plenty to explore and enjoy. There are 159 hotels and other accommodation options in the surrounding area. Find out more about Effingham.

What should I see while I'm in Effingham?

A favourite place to visit is Lynches River State Park. You'll also find Florence National Cemetery and Florence County Museum in the area. Take a look at what more there is to see and do in Expedia's Effingham guide.

What's the seasonal weather in Effingham?

The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 10°C. Average annual precipitation for Effingham is 1366 mm.

Effingham hotels from HK$515

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Effingham

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Effingham hotels

1. The Inn at the Crossroads

2. Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

3. Hyatt Place Florence Downtown

4. Comfort Inn & Suites Florence Center Area

5. Home2 Suites by Hilton Florence, SC

6. SpringHill Suites by Marriott Florence

7. Hampton Inn & Suites Florence Center

8. Park Inn by Radisson Florence, SC

9. Fairfield Inn & Suites by Marriott Florence I-20

10. Quality Inn Mullins - Marion

11. Staybridge Suites Florence - Civic Center by IHG

12. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

13. Howard Johnson by Wyndham Florence

14. Hotel Florence, Tapestry Collection by Hilton

15. Comfort Suites Florence I-95

16. Homewood Suites by Hilton Florence

17. Hampton Inn & Suites Florence-North-I-95

18. Best Western Executive Inn

19. TownePlace Suites by Marriott Florence

20. Spark by Hilton Florence North I-95, SC

Top Effingham Hotel Reviews

TownePlace Suites by Marriott Florence

Comfort Inn & Suites Florence Center Area

Hyatt Place Florence Downtown

The Inn at the Crossroads

Tru by Hilton Florence I-95

Days Inn by Wyndham Florence Near Civic Center

Hampton Inn & Suites Florence Center

Comfort Suites Florence I-95

Microtel Inn & Suites by Wyndham Florence

More cheap stays in Effingham

Days Inn by Wyndham Florence/I-95 North

Howard Johnson by Wyndham Florence

Park Inn by Radisson Florence, SC

Quality Inn & Suites Florence Civic Center

Comfort Inn & Suites Florence Center Area

Hampton Inn & Suites Florence Center

Frequently asked questions

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