A modern building with a curved glass facade, surrounded by a well-maintained lawn and several trees.

Florence Mcleod Regional Medical Center Hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
7 Aug - 9 Aug
Next weekend
14 Aug - 16 Aug

Filter by

Star rating

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Mcleod Regional Medical Center hotels

Terrace/patio

1. Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
3.0 star property
0.7 km from Mcleod Regional Medical Center
9.0 out of 10, Wonderful, (1,005 reviews)
"Clean room, helpful staff and good food"
United States
Mhd
The price is HK$894
HK$1,001 total
includes taxes & fees
12 Aug - 13 Aug
Hyatt Place Florence Downtown
Bar (on property)

2. Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
3.0 star property
0.8 km from Mcleod Regional Medical Center
8.8 out of 10, Excellent, (649 reviews)
"This is a beautiful place. We look forward to staying again"
United States
John
The price is HK$1,087
HK$1,217 total
includes taxes & fees
23 Aug - 24 Aug
Hotel Florence, Tapestry Collection by Hilton
Exterior

3. Rodeway Inn Florence Downtown

Rodeway Inn Florence Downtown
2.0 star property
1.2 km from Mcleod Regional Medical Center
5.8 out of 10, (7 reviews)
"Air conditioning didn’t work on my last night, neither did the WiFi. Would not recommend"
United States
F
The price is HK$333
HK$385 total
includes taxes & fees
2 Sept - 3 Sept
Rodeway Inn Florence Downtown
Private kitchen

4. The Urban Flats

The Urban Flats
4.0 star property
0.8 km from Mcleod Regional Medical Center
The price is HK$2,243
HK$3,688 total
includes taxes & fees
18 Aug - 19 Aug
The Urban Flats
Lobby

5. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
5.5 km from Mcleod Regional Medical Center
9.0 out of 10, Wonderful, (2,364 reviews)
"Staff very kind and the breakfast was excellent!"
United States
Kimberly
The price is HK$700
HK$784 total
includes taxes & fees
9 Aug - 10 Aug
Park Inn by Radisson Florence, SC
Exterior

6. Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
3.0 star property
8.1 km from Mcleod Regional Medical Center
9.4 out of 10, Exceptional, (1,004 reviews)
"Perfect for families"
United States
Stephen
The price is HK$1,059
HK$1,186 total
includes taxes & fees
16 Aug - 17 Aug
Staybridge Suites Florence - Civic Center by IHG
Indoor pool

7. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
2.5 star property
8 km from Mcleod Regional Medical Center
9.2 out of 10, Wonderful, (1,003 reviews)
"Good for overnight stay while going to Fl"
United States
Andrew
The price is HK$894
HK$1,001 total
includes taxes & fees
16 Aug - 17 Aug
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Restaurant

8. Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
2.5 star property
5.7 km from Mcleod Regional Medical Center
9.0 out of 10, Wonderful, (966 reviews)
"Beds were clean and comfy, quiet location, breakfast was great"
United States
Mariangela
The price is HK$862
HK$965 total
includes taxes & fees
10 Aug - 11 Aug
Hampton Inn & Suites Florence-North-I-95
Lobby

9. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
2.0 star property
5.5 km from Mcleod Regional Medical Center
8.6 out of 10, Excellent, (2,700 reviews)
"Amazing stay!"
United States
Miriam
The price is HK$522
HK$584 total
includes taxes & fees
5 Aug - 6 Aug
Howard Johnson by Wyndham Florence
Lobby

10. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
7 km from Mcleod Regional Medical Center
9.0 out of 10, Wonderful, (1,336 reviews)
"The staff made us feel like family!"
United States
Monica
The price is HK$907
HK$1,016 total
includes taxes & fees
1 Sept - 2 Sept
Comfort Inn & Suites Florence Center Area
Exterior

11. Affordable Suites Florence

Affordable Suites Florence
2.5 star property
7 km from Mcleod Regional Medical Center
9.2 out of 10, Wonderful, (203 reviews)
"Location is awesome and near everything the staff are very friendly and kind will definitely be coming back for more hotel stays"
United States
Cheyenne
The price is HK$486
HK$545 total
includes taxes & fees
11 Aug - 12 Aug
Affordable Suites Florence
Terrace/patio

12. Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
2.5 star property
5.9 km from Mcleod Regional Medical Center
8.6 out of 10, Excellent, (1,002 reviews)
"Easy parking, clean room, good breakfast."
United States
Tara
The price is HK$765
HK$888 total
includes taxes & fees
10 Aug - 11 Aug
Tru by Hilton Florence I-95
View from property

13. Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
3.0 star property
6.9 km from Mcleod Regional Medical Center
9.0 out of 10, Wonderful, (655 reviews)
"Everything from check in to check out was great. The location was amazing to. The Florence Center"
United States
Brian
The price is HK$960
HK$1,075 total
includes taxes & fees
9 Aug - 10 Aug
Fairfield Inn & Suites by Marriott Florence I-20
Premium bedding, pillow-top beds, desk, laptop workspace

14. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
3.0 star property
7 km from Mcleod Regional Medical Center
9.0 out of 10, Wonderful, (870 reviews)
"Clean room, friendly staff and delicious breakfast."
United States
Tameka
The price is HK$893
HK$1,000 total
includes taxes & fees
31 Aug - 1 Sept
TownePlace Suites by Marriott Florence
Lobby sitting area

15. Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
2.5 star property
5.5 km from Mcleod Regional Medical Center
8.4 out of 10, Very good, (239 reviews)
"Staff very friendly & accommodating for my family!"
United States
Samantha
The price is HK$706
HK$822 total
includes taxes & fees
18 Aug - 19 Aug
Spark by Hilton Florence North I-95, SC
Lobby

16. Residence Inn Marriott Florence

Residence Inn Marriott Florence
3.0 star property
7.2 km from Mcleod Regional Medical Center
8.8 out of 10, Excellent, (569 reviews)
"The breakfast was good."
United States
Michelle
The price is HK$960
HK$1,075 total
includes taxes & fees
9 Aug - 10 Aug
Residence Inn Marriott Florence
Exterior

17. Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
2.5 star property
9.1 km from Mcleod Regional Medical Center
8.6 out of 10, Excellent, (1,002 reviews)
"Great stay. Clean room, great breakfast"
United States
Tim
The price is HK$957
HK$1,149 total
includes taxes & fees
23 Aug - 24 Aug
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Restaurant

18. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
2.5 star property
7.2 km from Mcleod Regional Medical Center
9.0 out of 10, Wonderful, (939 reviews)
"Friendly staff and clean hotel."
United States
Stephanie
The price is HK$926
HK$1,037 total
includes taxes & fees
17 Aug - 18 Aug
Hampton Inn & Suites Florence Center
Lobby

19. Comfort Suites Florence I-95

Comfort Suites Florence I-95
2.5 star property
5.9 km from Mcleod Regional Medical Center
8.2 out of 10, Very good, (1,003 reviews)
"Great area and nice hotel!"
United States
Jennifer
The price is HK$691
HK$805 total
includes taxes & fees
31 Aug - 1 Sept
Comfort Suites Florence I-95
Premium bedding, desk, iron/ironing board, free cots/infant beds

20. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
2.5 star property
7.5 km from Mcleod Regional Medical Center
8.4 out of 10, Very good, (304 reviews)
"Friendly staff, clean rooms, great location for traveling through the area and breakfast included."
United States
Barbara
The price is HK$692
HK$775 total
includes taxes & fees
18 Aug - 19 Aug
Quality Inn & Suites Florence Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Mcleod Regional Medical Center Hotel Reviews

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

8/10 Good
"Convenient location next to I-95 and walkable restaurants. Room was clean a/c worked well and quiet. A bit musty and the sink had a slow drain. Breakfast was light but good."
Mitchell 1-night trip
Posted 1 hour ago
Howard Johnson by Wyndham Florence

Frequently asked questions

What's the area like around Mcleod Regional Medical Center?
Mcleod Regional Medical Center is located in a welcoming area of Florence known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 16 hotels and other accommodation options you'll find within a mile.
What's the best place to stay near Mcleod Regional Medical Center?
Hyatt Place Florence Downtown is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a restaurant. It's located just a short 0.4 mi (0.7 km) from Mcleod Regional Medical Center. Other good options within a short distance include Hotel Florence, Tapestry Collection by Hilton and Rodeway Inn Florence Downtown.
How many hotels can I expect to find near Mcleod Regional Medical Center?
Expedia has 16 hotels and other accommodation options within a mile from Mcleod Regional Medical Center.
If I need to cancel the hotel reservation for my stay near Mcleod Regional Medical Center, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view top deals close to Mcleod Regional Medical Center.
What can I see and do near Mcleod Regional Medical Center?
You might spend a leisurely day outdoors at Florence Veterans Park and Greenwood Baseball Park and Playground. You might plan a visit to Dr. Eddie Floyd Tennis Center or Regal Swamp Fox while you're in the area. Florence Museum and Magnolia Mall are both worth a visit while you're out exploring.

Explore a world of travel with Expedia