Florence Mcleod Regional Medical Center Hotels: 2026 Limited-Time Hotel Deals @Expedia

A modern building with a curved glass facade, surrounded by a well-maintained lawn and several trees.

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Our top choices for Mcleod Regional Medical Center hotels

A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.

A modern lounge area with brick walls, large windows, and contemporary furniture.

A modern bar area with a long counter, bar stools, and a variety of bottles and glasses.

A modern bar area with a long counter, multiple bar stools, and a variety of bottles and glasses.

1. Hyatt Place Florence Downtown

0.7 km from Mcleod Regional Medical Center

Shanti

HK$863

HK$966 total

includes taxes & fees

12 Oct - 13 Oct

A restaurant with brick walls, framed awards, and a bar area.

A bar area with a curved counter, multiple stools, and a brick wall backdrop.

A spacious kitchen with a dining area, a living room with a fireplace, and a cozy seating arrangement.

A spacious living room with a wooden floor, a ceiling fan, and a dining area with a wooden table and chairs.

2. Hotel Florence, Tapestry Collection by Hilton

0.8 km from Mcleod Regional Medical Center

Ankh

HK$994

HK$1,113 total

includes taxes & fees

22 Oct - 23 Oct

3. Rodeway Inn Florence Downtown

1.2 km from Mcleod Regional Medical Center

HK$333

HK$385 total

includes taxes & fees

25 Oct - 26 Oct

A modern kitchen with stainless steel appliances, a gray sofa, and a ceiling fan.

A modern kitchen with grey cabinets, stainless steel appliances, and bar stools.

A modern living room with a brick wall, a grey sofa, a wooden coffee table, and a view through large windows.

A modern living room with a grey sofa, a round coffee table, a grey armchair with patterned cushions, a floor lamp, and a large TV mounted on the wall.

4. The Urban Flats

0.8 km from Mcleod Regional Medical Center

HK$2,243

HK$3,689 total

includes taxes & fees

28 Sept - 29 Sept

A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.

A modern hotel with a 'Park Inn by Radisson' sign, featuring a covered entrance, multiple windows, and a parking lot.

A modern kitchen with a patterned backsplash, wooden cabinets, and stainless steel appliances.

A modern living room with a grey sofa, a flat-screen TV, geometric wall art, and a bookshelf with decorative items.

5. Park Inn by Radisson Florence, SC

5.5 km from Mcleod Regional Medical Center

Windia

HK$700

HK$784 total

includes taxes & fees

11 Oct - 12 Oct

A hotel lobby with a reception desk, seating area, and a television screen.

A spacious dining area with multiple tables and chairs, large windows, and a flat-screen TV mounted on the wall.

A Comfort Inn & Suites hotel with a covered entrance, brick facade, and multiple windows.

A hotel room with a sectional sofa, two ottomans, a bed with a green bedspread, and framed pictures on the wall.

6. Comfort Inn & Suites Florence Center Area

7 km from Mcleod Regional Medical Center

Mila

HK$793

HK$889 total

includes taxes & fees

14 Oct - 15 Oct

A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.

A corridor with shelves stocked with snacks and a frozen food display.

A lobby with leather sofas, a coffee table, potted plants, and a reception desk.

A Hampton Inn & Suites hotel with a well-lit entrance, multiple floors, and a parking area.

7. Hampton Inn & Suites Florence-North-I-95

5.7 km from Mcleod Regional Medical Center

Michelle

HK$926

HK$1,037 total

includes taxes & fees

30 Sept - 1 Oct

A hotel room with two beds, a desk with a TV, and a bathroom visible through an open door.

A large, two-story building with a central entrance flanked by columns, labeled "DIR FRANK B. LEE NURSING BUILDING."

A Holiday Inn Express & Suites hotel with a clear entrance, a covered parking area, and a well-maintained exterior.

A hotel lobby with a reception desk, a seating area with green sofas, and a dining area with tables and chairs.

8. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

9.1 km from Mcleod Regional Medical Center

Christopher

HK$925

HK$1,114 total

includes taxes & fees

27 Sept - 28 Sept

A spacious lobby with a checkered floor, a reception desk, and a chandelier.

A hotel room with two beds, a desk with a computer, a chair, and a bathroom with a mirror.

A spacious dining area with multiple tables and chairs, large windows offering a view of the parking lot, and a television mounted on the wall.

A two-story building with a brick facade, a flat roof, and a covered entrance area.

9. Howard Johnson by Wyndham Florence

5.5 km from Mcleod Regional Medical Center

HOMERO

HK$507

HK$567 total

includes taxes & fees

28 Sept - 29 Sept

A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.

A self-service beverage station with refrigerated and non-refrigerated drink options, snack shelves, and a sign indicating the location.

A modern lounge area with a sofa, armchairs, and small tables.

A reception area with a wooden desk, a map on the wall, and a sign welcoming visitors to Florence, SC.

10. TownePlace Suites by Marriott Florence

7 km from Mcleod Regional Medical Center

William

HK$927

HK$1,038 total

includes taxes & fees

27 Sept - 28 Sept

A building with two red doors, one labeled 'Office' and the other '101'. There is a welcome sign and a mailbox on the wall.

A room with a sofa, a small table, a chair, a lamp, and a door.

A house with a stone-paved entrance, a bench, and two red doors labeled "OFFICE" and "PRIVATE."

A compact living space with a dining area, kitchenette, and seating area.

11. Affordable Suites Florence

7 km from Mcleod Regional Medical Center

Cheyenne

HK$565

HK$632 total

includes taxes & fees

21 Oct - 22 Oct

A hotel entrance with a stone facade, glass doors, and a number '501' above.

An indoor swimming pool with a tiled floor, a pool ladder, and lounge chairs.

A modern living room with a stone fireplace, a blue sofa, a brown leather chair, and a round coffee table.

A hotel reception area with a wooden floor, a reception desk, a seating area with chairs, and a decorative wall with a tree pattern.

12. Fairfield Inn & Suites by Marriott Florence I-20

6.9 km from Mcleod Regional Medical Center

Felecia

HK$993

HK$1,112 total

includes taxes & fees

1 Oct - 2 Oct

An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.

A modern hotel restaurant with a breakfast bar, seating area, and a view of the city.

A modern lounge area with seating, tables, and a pool table.

A snack kiosk with a variety of snacks and beverages, a sign for a 24/7 market, and a sign for local items.

13. Tru by Hilton Florence I-95

5.9 km from Mcleod Regional Medical Center

Tiffany

HK$765

HK$904 total

includes taxes & fees

30 Sept - 1 Oct

A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.

A hotel entrance with a covered walkway, a brick pathway, and a well-maintained garden.

A hotel room with a sofa, a dining table, a coffee maker, a TV, and artwork on the wall.

A swimming pool area with lounge chairs and umbrellas, surrounded by a white building with large windows.

14. Staybridge Suites Florence - Civic Center by IHG

8.1 km from Mcleod Regional Medical Center

Denay

HK$1,059

HK$1,186 total

includes taxes & fees

27 Sept - 28 Sept

A modern lobby with seating areas, a reception desk, and a large wall with a decorative panel.

An outdoor patio area with tables and chairs, a barbecue grill, and a large window overlooking a fenced area.

A hotel room with a bed, a blue sofa, a brown ottoman, a black office chair, a desk, a lamp, and three framed pictures on the wall.

A Comfort Suites hotel with a modern design, featuring a prominent entrance with columns, a covered walkway, and a clear blue sky.

15. Comfort Suites Florence I-95

5.9 km from Mcleod Regional Medical Center

Denise

HK$685

HK$799 total

includes taxes & fees

18 Oct - 19 Oct

A spacious lobby with a reception desk, seating area, and large windows.

An indoor swimming pool with clear poolside areas, a lifeguard station, and a view of the outside.

A reception area with a counter, a sign for 'The Pavilion Pantry', and a green wall.

A spacious lobby with a large fireplace, comfortable seating, and potted plants.

16. Hilton Garden Inn Florence

7.2 km from Mcleod Regional Medical Center

Derrick

HK$894

HK$1,001 total

includes taxes & fees

18 Oct - 19 Oct

A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.

A lobby with a fireplace, seating area, and a television.

A hotel room with two beds, a desk, a TV, and a window with patterned curtains.

A Hampton Inn & Suites with a large sign, brick facade, and a parking lot.

17. Hampton Inn & Suites Florence Center

7.2 km from Mcleod Regional Medical Center

Bill

HK$862

HK$965 total

includes taxes & fees

25 Oct - 26 Oct

A hotel room with a large bed, a desk with a chair, a television, and a walk-in closet.

A modern restaurant with red upholstered chairs, a flat-screen TV mounted on the wall, and a ceiling with recessed lighting.

An outdoor patio area with lounge chairs and tables, a brick building, and a clear sky.

A coffee station with two coffee machines and a display of coffee pods and cups.

18. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

8 km from Mcleod Regional Medical Center

Leigh

HK$996

HK$1,116 total

includes taxes & fees

27 Sept - 28 Sept

A reception desk with a stone wall backdrop, a sign reading 'Quality Choice Hotels,' and a reception area with a wooden reception desk and two chairs.

A swimming pool with lounge chairs and a building with balconies.

A hotel dining area with wooden tables and chairs, a fireplace, and a television.

A hotel with a green roof, a sign reading 'Quality Inn & Suites by Choice Hotels,' and a landscaped front yard with small trees and shrubs.

19. Quality Inn & Suites Florence Civic Center

7.5 km from Mcleod Regional Medical Center

Noémie

HK$748

HK$838 total

includes taxes & fees

3 Oct - 4 Oct

A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.

A hotel room with two beds, a desk with a chair, a television, and a window with curtains.

An outdoor patio with a wooden table and wicker chairs, a barbecue grill, and a swimming pool in the background.

A modern cafeteria with long wooden tables, green chairs, and yellow accents.

20. Spark by Hilton Florence North I-95, SC

5.5 km from Mcleod Regional Medical Center

Michelle

HK$637

HK$744 total

includes taxes & fees

18 Oct - 19 Oct

View all properties

Top Mcleod Regional Medical Center Hotel Reviews

Spark by Hilton Florence North I-95, SC

8/10 Good

"Better mattressea and pillows. Bother were very soft, unsupportive and uncomfortable."

Quality Inn & Suites Florence Civic Center

10/10 Excellent

"Great stay! Would definitely stay again!"

Best Western Inn

8/10 Good

"Front desk staff was helpful and friendly. My room was clean and the bed was comfortable. The breakfast was very good. Nice to have scrambled eggs and some sausage links for protein plus many other things too. Folgers coffee on tap is awesome!! I would stay here again 4.5 out of 5."

La Quinta Inn & Suites by Wyndham Florence

10/10 Excellent

"We stop here a few times a year on our pilgrimage from NJ to Fl with our dogs. It’s conveniently located, staff is friendly, rooms are clean, bfast in the Am - and it’s very affordable."

Super 8 by Wyndham Florence

8/10 Good

"Clean room, nice staff."

Hyatt Place Florence Downtown

10/10 Excellent

"Very clean, nice staff and good breakfast"

Comfort Suites Florence I-95

10/10 Excellent

"Breakfast was hot and delicious. Room was comfortable"

Days Inn by Wyndham Florence Near Civic Center

10/10 Excellent

"Clean and easy access to restaurants"

Hotel Florence, Tapestry Collection by Hilton

10/10 Excellent

"Beautiful boutique like hotel. Will definitely stay there again!"

Frequently asked questions

What's the area like around Mcleod Regional Medical Center?

Mcleod Regional Medical Center is located in a welcoming area of Florence known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 18 hotels and other accommodation options you'll find within a mile.

What's the best place to stay near Mcleod Regional Medical Center?

Hyatt Place Florence Downtown is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a restaurant. It's located just a short 0.4 mi (0.7 km) from Mcleod Regional Medical Center. Other good options within a short distance include Hotel Florence, Tapestry Collection by Hilton and The Urban Flats.

How many hotels can I expect to find near Mcleod Regional Medical Center?

Expedia has 18 hotels and other accommodation options within a mile from Mcleod Regional Medical Center.

If I need to cancel the hotel reservation for my stay near Mcleod Regional Medical Center, will I receive a refund?

Yes! You'll find that most hotel reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view top deals close to Mcleod Regional Medical Center.

What can I see and do near Mcleod Regional Medical Center?

You can enjoy live performances at FMU Performing Arts Center and Florence Little Theatre. You might spend a leisurely day outdoors at Florence Veterans Park and Greenwood Baseball Park and Playground. Create some family memories at Sky Zone Trampoline Park and Tilt Studio.

Florence Mcleod Regional Medical Center Hotels

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for Mcleod Regional Medical Center hotels

1. Hyatt Place Florence Downtown

2. Hotel Florence, Tapestry Collection by Hilton

3. Rodeway Inn Florence Downtown

4. The Urban Flats

5. Park Inn by Radisson Florence, SC

6. Comfort Inn & Suites Florence Center Area

7. Hampton Inn & Suites Florence-North-I-95

8. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

9. Howard Johnson by Wyndham Florence

10. TownePlace Suites by Marriott Florence

11. Affordable Suites Florence

12. Fairfield Inn & Suites by Marriott Florence I-20

13. Tru by Hilton Florence I-95

14. Staybridge Suites Florence - Civic Center by IHG

15. Comfort Suites Florence I-95

16. Hilton Garden Inn Florence

17. Hampton Inn & Suites Florence Center

18. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

19. Quality Inn & Suites Florence Civic Center

20. Spark by Hilton Florence North I-95, SC

Top Mcleod Regional Medical Center Hotel Reviews

Spark by Hilton Florence North I-95, SC

Quality Inn & Suites Florence Civic Center

Best Western Inn

La Quinta Inn & Suites by Wyndham Florence

Super 8 by Wyndham Florence

Hyatt Place Florence Downtown

Comfort Suites Florence I-95

Days Inn by Wyndham Florence Near Civic Center

Hotel Florence, Tapestry Collection by Hilton

Frequently asked questions

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