Raleigh Museum of Life and Science Hotels: 2026 Limited-Time Hotel Deals @Expedia

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Our top choices for Museum of Life and Science hotels

A breakfast area with a chalkboard menu, a sign indicating breakfast starts here, and a variety of food items like waffles, oatmeal, and fruits.

A hotel room with a bed, a desk with a chair, a flat-screen TV, a microwave, and a mirror.

A Hampton Inn hotel with a modern facade, multiple floors, and a parking lot.

A large indoor swimming pool with clear blue water, surrounded by beige tiled flooring and walls, with large windows allowing natural light.

1. Hampton Inn & Suites Durham/North I-85

1.4 km from Museum of Life and Science

Shwetha

HK$960

HK$1,090 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with two beds, a flat-screen TV, a wooden headboard, and a carpeted floor.

A hotel lobby with a seating area, a reception desk, and artwork on the walls.

A coffee station with two coffee machines, a coffee press, and various coffee-related items on a counter.

A swimming pool with a metal railing, surrounded by a building with multiple windows and a sign indicating no lifeguard on duty.

2. Holiday Inn Express Durham by IHG

2.2 km from Museum of Life and Science

Kimberly R

HK$808

HK$918 total

includes taxes & fees

15 Nov - 16 Nov

A hotel room with a bed, a desk, a chair, a small table, a coffee machine, and a trash bin.

A Comfort Inn & Suites hotel with a modern design, featuring a prominent entrance and a landscaped front yard.

A swimming pool with lounge chairs and umbrellas, surrounded by a building with a clear sky.

A reception area with a wooden reception desk, blue seating, a flat-screen TV, and a stone accent wall.

3. Comfort Inn & Suites Durham near Duke University

Croasdaile Farm Master, 3.2 km from Museum of Life and Science

Chrissy

HK$685

HK$778 total

includes taxes & fees

25 Oct - 26 Oct

A hotel room with a television on a wooden cabinet, a desk with a chair, and a lamp.

A Red Roof Inn with a modern architectural design, featuring a prominent red sign and a well-maintained lawn.

A hotel room with a bed, bedside tables, a nightstand, a mirror, and a bathroom with a sink and mirror.

A spacious hallway with wooden flooring, white walls, and multiple windows with blinds. There are two white chairs and a small table with a basket.

4. Red Roof Inn Durham - Duke Univ Medical Center

2.2 km from Museum of Life and Science

Luis

HK$492

HK$572 total

includes taxes & fees

1 Nov - 2 Nov

An outdoor patio area with round tables and chairs, large umbrellas, and a glass door entrance.

A hotel room with two beds, a desk, a chair, a sofa, and a TV.

A multi-story hotel with a brick facade, large windows, and a well-lit entrance.

A modern restaurant with round tables and yellow chairs, a bar area, and a 'Hello Fall' sign.

5. Fairfield by Marriott Inn & Suites Durham

17.3 km from Museum of Life and Science

Chip

HK$931

HK$1,057 total

includes taxes & fees

30 Oct - 31 Oct

A stone fire pit surrounded by striped chairs and tables in an outdoor lounge area with a view of a building in the background.

A modern hotel lobby with a reception desk, seating area, and a cityscape mural on the wall.

A Hampton Inn & Suites hotel with a modern facade, multiple windows, and a parking lot.

An indoor swimming pool with clear blue water, surrounded by lounge chairs and a tiled floor.

6. Hampton Inn & Suites Durham University Medical Center

4.8 km from Museum of Life and Science

Nicole

HK$994

HK$1,128 total

includes taxes & fees

25 Oct - 26 Oct

A modern hotel building with a prominent 'HOME 2' sign, multiple windows, and a flagpole with an American flag.

A swimming pool with a tiled deck, surrounded by lounge chairs and tables.

A multi-story hotel with a prominent 'HOME 2' sign, a large parking lot, and a well-lit entrance.

A modern interior with multiple seating areas, a flat-screen TV, and a variety of decorative items on shelves.

7. Home2 Suites by Hilton Durham University Medical Center

4.8 km from Museum of Life and Science

katey

HK$1,127

HK$1,279 total

includes taxes & fees

25 Oct - 26 Oct

A modern lobby with a central seating area, a TV screen, and a patterned wall.

A modern hotel room with a bed, bedside table, TV, and a small desk area.

A reception area with a counter, a welcome sign, a digital screen, and a hallway leading to a dining area.

An indoor swimming pool with clear water, surrounded by lounge chairs and potted plants.

8. Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

17.5 km from Museum of Life and Science

Maurice

HK$927

HK$1,049 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor patio with a stone fire pit, seating, and a covered area.

A modern dining area with wooden tables and chairs, a kitchen in the background, and a counter with stools.

A hotel room with a bed, a desk, and a chair. There is a door and a wall-mounted lamp.

A multi-story hotel with a 'TOWNEPLACE' sign, a covered entrance, and a parking area with cars.

9. Towneplace Suites By Marriott Raleigh-Durham Airport/Morrisville

19.7 km from Museum of Life and Science

Robel

HK$793

HK$898 total

includes taxes & fees

1 Nov - 2 Nov

A modern restaurant with long communal tables, hanging pendant lights, and geometric patterned walls.

A modern living room with a pool table, a sofa, and a dining area.

An outdoor dining area with tables and chairs, large windows, and a view of greenery.

10. The Westin Raleigh-Durham Airport

17.5 km from Museum of Life and Science

Dina

HK$1,687

HK$1,911 total

includes taxes & fees

1 Nov - 2 Nov

A brick pathway flanked by neatly trimmed hedges leading to a building with a red facade and a grey roof.

A restaurant with brick walls, wooden tables, and blue chairs.

A modern living room with two sofas facing a glass coffee table, a large window with curtains, and a brick wall.

A spacious lobby with a long corridor, comfortable seating areas, and large windows providing natural light.

11. Rizzo Center, a Destination by Hyatt Hotel

16.3 km from Museum of Life and Science

Andrea

HK$1,405

HK$1,594 total

includes taxes & fees

1 Nov - 2 Nov

A bar area with wooden bar stools, pendant lighting, and a counter with a glass display. There are tables and chairs in the background, and the room has a wooden floor.

A bar area with wooden shelves, a chalkboard menu, and various bottles.

A covered porch with steps leading to a door, a brick wall, and a street lamp.

A hotel room with two beds, a sofa, a TV, and a bathroom visible through a door.

12. The Colonial Inn, an Ascend Collection Hotel

18.9 km from Museum of Life and Science

Matt W

HK$852

HK$967 total

includes taxes & fees

25 Oct - 26 Oct

A swimming pool with lounge chairs and a wooden fence.

A multi-story hotel with a modern design, featuring a prominent entrance with a glass canopy and an American flag.

A hotel room with a bed, a sofa, a desk with a chair, a television, and a painting on the wall.

A modern bar area with a refrigerated display, wooden bar counter, and seating.

13. Hyatt Place Durham Southpoint

15.3 km from Museum of Life and Science

Jessica

HK$1,059

HK$1,202 total

includes taxes & fees

25 Oct - 26 Oct

A spacious lobby with high ceilings, a central fountain, and seating areas.

An outdoor patio area with wicker furniture, stone pillars, and string lights.

A modern bedroom with a large bed, a fireplace, a walk-in closet, and a bathroom with a round mirror and vanity.

A bar area with multiple liquor cabinets and hanging pendant lights.

14. Embassy Suites by Hilton Raleigh Durham Airport Brier Creek

17.5 km from Museum of Life and Science

Darren C.

HK$1,248

HK$1,414 total

includes taxes & fees

25 Oct - 26 Oct

A hotel entrance with a stone facade, large wooden doors, and a view into the interior.

A person performing a yoga pose outdoors with trees and a golf course in the background.

A hotel with a stone lion statue, a covered entrance, and a landscaped garden.

An indoor swimming pool with clear blue water, surrounded by lounge chairs and potted plants.

15. Washington Duke Inn & Golf Club

5.9 km from Museum of Life and Science

Lowell

HK$1,883

HK$2,137 total

includes taxes & fees

25 Oct - 26 Oct

An indoor swimming pool with clear water, a no diving sign, and a seating area with chairs and tables.

A modern hotel lobby with a reception desk, several chairs, a large monitor, and pendant lighting.

A modern kitchen with built-in shelves, a glass backsplash, and a variety of kitchenware.

A modern hotel lobby with a sectional sofa, armchairs, and a coffee table.

16. Hyatt House Raleigh / RDU / Brier Creek

17.1 km from Museum of Life and Science

Shelby

HK$863

HK$978 total

includes taxes & fees

1 Nov - 2 Nov

A reception area with two wooden reception desks, a potted plant, and a computer on the wall.

A hotel room with two beds, a desk, a chair, a TV, and a bathroom.

An indoor swimming pool with clear water, a lifeguard chair, and a sign indicating no diving.

17. Courtyard Raleigh-Durham Airport/Brier Creek

15.9 km from Museum of Life and Science

Sharon

HK$1,015

HK$1,150 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor seating area with sofas, chairs, and a fire pit, adjacent to a modern building with large windows.

A modern bar area with a long counter, multiple bar stools, and a large screen displaying a sports event.

A modern reception area with a marble counter, a wooden bench, and a unique chandelier.

A modern living room with a fireplace, seating area, and a pool table.

18. JB Duke Hotel

5.6 km from Museum of Life and Science

samantha

HK$1,562

HK$1,772 total

includes taxes & fees

18 Oct - 19 Oct

An outdoor seating area with wicker furniture and a stone fire pit.

A conference room with a long table, chairs, and a modern chandelier.

A modern hotel lobby with seating areas, large windows, and a dining section.

A hotel lobby with a sofa, chairs, a table, and a large window offering a view of the building.

19. Residence Inn Raleigh-Durham Airport/Brier Creek

15.9 km from Museum of Life and Science

Janet

HK$1,094

HK$1,239 total

includes taxes & fees

31 Oct - 1 Nov

A hotel room with two beds, wooden flooring, and a blue accent wall.

A hotel reception area with a wooden reception desk, large windows, and a circular ceiling design.

A fitness center with treadmills, a bench, and a dumbbell rack.

A breakfast counter with various food items and a sign that reads 'TOP IT BREAKFAST'.

20. Tru by Hilton Raleigh Durham Airport

19.7 km from Museum of Life and Science

Muthukumar

HK$861

HK$975 total

includes taxes & fees

1 Nov - 2 Nov

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Compare popular hotels close to Museum of Life and Science

Property	Property class	Guest rating
Hampton Inn & Suites Durham/North I-85	9.0 Wonderful 1,000 reviews	View
Holiday Inn Express Durham by IHG	8.8 Excellent 1,000 reviews	View
Comfort Inn & Suites Durham near Duke University	8.6 Excellent 1,176 reviews	View
Red Roof Inn Durham - Duke Univ Medical Center	6.8 1,001 reviews	View
Fairfield by Marriott Inn & Suites Durham	9.6 Exceptional 60 reviews	View

Top Museum of Life and Science Hotel Reviews

Hampton Inn & Suites Durham/North I-85

10/10 Excellent

"Very clean room, and friendly staff"

Everything within 1 mile

10/10 Excellent

"This home is thoughtfully laid out and much more spacious than it looks in photos. Our kids enjoyed the snacks each night, and their grandma loved that the home is all one level with smooth floors and bright lighting. Location was perfect for attending events in Durham, Wake Forest and Raleigh. There's also a running path across the street."

Unscripted Durham, Part of JDV by Hyatt

8/10 Good

"The place was awesome! I'm not going into details....I came home with some bed bug bites......🤔"

Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit

10/10 Excellent

"The house was absolutely immaculate and Kristin could not have nicer or more helpful. The location was just 25 minutes from RDU, 12 minutes from downtown Durham and about a half an hour from Chapel Hill. Comfortable living room for my small group, large screen TV with all the streaming channels and a very cool coffee grinder/maker for regular or espresso coffee. Highly recommend. John L"

Medical & Work Stay · Quiet · Fenced Pet · Friendly

10/10 Excellent

"This home was perfect for us and our dogs. Very clean and nice and the beds were super comfortable! The hosts were extremely responsive when a minor matter arose. Highly recommend!!!"

NEW! Renovated 2Br/1Ba Convenient to 9th St, NCSSM

10/10 Excellent

"this stay reminded me of a time when vacation rentals used to be clean and neat with thoughtful touches like extra blankets and a few extras of things you might have forgotten (toothpaste, coffee and tea); in other words, it was exactly that and i really appreciated it."

Cottage with Yard, Mins to Duke

10/10 Excellent

"This was a cheerful home with comfortable beds and many thoughtful extras. We enjoyed our time here."

New & Renovated Charming Bungalow near DT Durham

10/10 Excellent

"quiet neighborhood and cozy home close to anything you’d need in durham. bed was comfy, shower was good, all is well!"

Clean, Cozy, Quiet and Walkable — Near Ellerbee Trail + Downtown

8/10 Good

"Everything you need for a nice stay with your dog. The unit is a duplex with a fenced backyard and private parking. The neighborhood looked a little sketchy at first but after a few days, we found the neighbors very nice and welcoming. It is located very close to downtown with easy access to downtown and Duke. The turn into Washington from Greene St is dicey as visibility is poor, but the other direction is no problem. Overall comfortable, clean and has everything you need."

Other attractions near Museum of Life and Science

Brightleaf Square

9.6/10 (8 reviews)

You can do some window-shopping at Brightleaf Square during your visit to Durham. Discover the lively festivals and stunning cathedral in this family-friendly area.

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Vietnam Veterans Living Memorial

You can find out about the history of Durham with a trip to Vietnam Veterans Living Memorial. Attend a sporting event or visit the stunning cathedral in this family-friendly area.

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Northgate Mall

8.2/10 (60 reviews)

You can search for that perfect souvenir at Northgate Mall during your stay in Durham. Experience the lively festivals or attend a sporting event in this family-friendly area.

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Duke Homestead

Learn about the local history of Durham when you take a trip to Duke Homestead. Attend a sporting event or visit the stunning cathedral in this family-friendly area.

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Fullsteam Brewery

7.4/10 (3 reviews)

You can take time to visit Fullsteam Brewery during your travels to Durham. Experience the lively festivals or attend a sporting event in this family-friendly area.

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Durham Convention Center

8.2/10 (118 reviews)

Learn about the events happening in Durham Convention Center during your trip to Durham. Discover the entertainment choices and stunning cathedral in this family-friendly area.

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African American Dance Ensemble

8.8/10 (3 reviews)

You can enjoy some culture when you stop by African American Dance Ensemble in Durham.

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Carolina Theatre

8.2/10 (220 reviews)

You can get tickets for a performance at Carolina Theatre during your stay in Durham. Experience the area's entertainment choices or attend a sporting event.

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Frequently asked questions

What's the area like around Museum of Life and Science?

Museum of Life and Science is located in an area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, take a look at the 10 hotels and other accommodation options you'll find within a mile.

What's the best hotel to stay near Museum of Life and Science?

Hampton Inn & Suites Durham/North I-85 is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. It's located just a short 0.8 mi (1.4 km) from Museum of Life and Science. Other good options within 5 miles include Holiday Inn Express Durham by IHG and Red Roof Inn Durham - Duke Univ Medical Center.

How many hotels can I expect to find close to Museum of Life and Science?

Expedia has 10 hotels and other accommodation options within a mile from Museum of Life and Science.

If I need to cancel the hotel reservation for my stay near Museum of Life and Science, will I receive a refund?

Yes, the majority of hotel room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the best deals near Museum of Life and Science.

What can I see and do near Museum of Life and Science?

You'll want to browse the exhibits at Nasher Museum of Art at Duke University and Bennett Place. Explore landmarks like American Tobacco Campus, Cameron Indoor Stadium and Wallace Wade Stadium. You can enjoy live performances at Carolina Theatre and Common Ground Theatre.

Raleigh Museum of Life and Science Hotels

Change your mind

Treat yourself

Be picky

Check prices for these dates

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Star rating

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Our top choices for Museum of Life and Science hotels

1. Hampton Inn & Suites Durham/North I-85

2. Holiday Inn Express Durham by IHG

3. Comfort Inn & Suites Durham near Duke University

4. Red Roof Inn Durham - Duke Univ Medical Center

5. Fairfield by Marriott Inn & Suites Durham

6. Hampton Inn & Suites Durham University Medical Center

7. Home2 Suites by Hilton Durham University Medical Center

8. Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

9. Towneplace Suites By Marriott Raleigh-Durham Airport/Morrisville

10. The Westin Raleigh-Durham Airport

11. Rizzo Center, a Destination by Hyatt Hotel

12. The Colonial Inn, an Ascend Collection Hotel

13. Hyatt Place Durham Southpoint

14. Embassy Suites by Hilton Raleigh Durham Airport Brier Creek

15. Washington Duke Inn & Golf Club

16. Hyatt House Raleigh / RDU / Brier Creek

17. Courtyard Raleigh-Durham Airport/Brier Creek

18. JB Duke Hotel

19. Residence Inn Raleigh-Durham Airport/Brier Creek

20. Tru by Hilton Raleigh Durham Airport

Compare popular hotels close to Museum of Life and Science

Top Museum of Life and Science Hotel Reviews

Hampton Inn & Suites Durham/North I-85

Everything within 1 mile

Unscripted Durham, Part of JDV by Hyatt

Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit

Medical & Work Stay · Quiet · Fenced Pet · Friendly

NEW! Renovated 2Br/1Ba Convenient to 9th St, NCSSM

Cottage with Yard, Mins to Duke

*New & Renovated* Charming Bungalow near DT Durham

Clean, Cozy, Quiet and Walkable — Near Ellerbee Trail + Downtown

Other attractions near Museum of Life and Science

Brightleaf Square

Vietnam Veterans Living Memorial

Northgate Mall

Duke Homestead

Fullsteam Brewery

Durham Convention Center

African American Dance Ensemble

Carolina Theatre

Frequently asked questions

New & Renovated Charming Bungalow near DT Durham