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Santa Ana hotels in Cusco

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Our top choices for Santa Ana hotels

ZEVEN HOUSE - CUSCO APARTMENT

ZEVEN HOUSE - CUSCO APARTMENT
2.0 star property
Santa Ana
10.0 out of 10, Exceptional, (1)
"My wife and I are visiting Cusco from Dallas, Texas. We had a wonderful stay. The host spoke English and was very kind and helpful. He showed us how to operate the appliances. There was hot water in the shower, a gas stove, washing machine, refrigerator, TV with Netflix (big plus), and electric portable space heater (another big plus). The beds were very comfortable and warm. Wi-fi was fast and reliable. The place was quiet at night. Short walking distance to Orion grocery store. Definitely...
United States
Andrew
The price is HK$389
HK$389 total
1 Jan - 2 Jan 2026
ZEVEN HOUSE - CUSCO APARTMENT

Anata Hostel

Anata Hostel
3.0 star property
Santa Ana
8.8 out of 10, Excellent, (21)
"Great location, staff incredible!"
Canada
christiane
The price is HK$187
HK$187 total
2 Jan - 3 Jan 2026
Anata Hostel

Tucan Hostel

Tucan Hostel
2.0 star property
Santa Ana
8.4 out of 10, Very good, (14)
"We found this hostel to be a very special place, filled with wonderfully helpful and pleasant folks. We would highly recommend a stay."
United States
Anonymous traveller
The price is HK$241
HK$241 total
8 Jan - 9 Jan 2026
Tucan Hostel

Hotel Cusco Pacha Inti

Hotel Cusco Pacha Inti
3.0 star property
Santa Ana
6.0 out of 10, (1)
"El hotel cumple con sus funciones, sin embargo es complicado el tema de la regadera, considero es un punto que pueden mejorar. El hotel no está alejado del centro pero está en una zona no tan cómoda de llegar, ni siquiera los autos tienen accedió tan fácil. El personal es muy atento y amable, sin embargo tuve que pagar dos veces la reservación porque a ellos "no se les reflejaba" siendo que ellos mismos confirmaron que tienen problemas con expedis y Booking y a pesar de que les mostré en mi...
Mexico
CR
The price is HK$225
HK$225 total
7 Jan - 8 Jan 2026
Hotel Cusco Pacha Inti

Tierra Viva Cusco Saphi

Tierra Viva Cusco Saphi
3.0 star property
Santa Ana
9.4 out of 10, Exceptional, (500)
"Great place ! "
United States
Roger
Tierra Viva Cusco Saphi

HOSTAL LA RASA

HOSTAL LA RASA
2.0 star property
Santa Ana
10.0 out of 10, Exceptional, (2)
"Accueil très agréable !"
France
Lia
The price is HK$154
HK$154 total
4 Jan - 5 Jan 2026
HOSTAL LA RASA

Hilton Garden Inn Cusco

Hilton Garden Inn Cusco
3.5 star property
Santa Ana
9.2 out of 10, Wonderful, (1001)
"great hotel"
United States
Rodolfo
The price is HK$880
HK$968 total
10 Jan - 11 Jan 2026
Hilton Garden Inn Cusco

Hotel Mamasara

Hotel Mamasara
3.0 star property
Santa Ana
8.4 out of 10, Very good, (18)
"It was nice"
United States
Alexander
Hotel Mamasara

Munay Ñusta Cusco

Munay Ñusta Cusco
3.0 star property
Santa Ana
9.6 out of 10, Exceptional, (4)
"Very nice property"
United States
Arthur
Munay Ñusta Cusco

Santa Ana Departamentos

Santa Ana Departamentos
2.0 star property
Santa Ana
9.0 out of 10, Wonderful, (4)
"Grand appartement à 10 min à pied de la place des Armes. Il y a également un bus qui s'arrête devant le portail. Nous sommes toujours descendus à pied et remontés en navette. Eau chaude, appartement un peu froid mais pas insurmontable. Accueil très sympathique et agréable de la part des propriétaires, n'hésitez pas à leur demander conseils ou de l'aide ils feront tout pour vous aider. Nous avons passé un excellent séjour grâce à eux."
France
Mélissa
Santa Ana Departamentos

Centro by Casa Andina Cusco Saphi

Centro by Casa Andina Cusco Saphi
3.0 star property
Santa Ana
9.0 out of 10, Wonderful, (12)
"A pleasant place to visit Cuzco"
France
Michel
Centro by Casa Andina Cusco Saphi

Hotel El Mirador de Santa Ana

Hotel El Mirador de Santa Ana
3.0 star property
Santa Ana
The price is HK$248
HK$248 total
1 Jan - 2 Jan 2026
Hotel El Mirador de Santa Ana

Munay Cusco

Munay Cusco
2.0 star property
Santa Ana
The price is HK$137
HK$137 total
1 Jan - 2 Jan 2026
Munay Cusco

Casa Karmenka

Casa Karmenka
2.5 star property
Santa Ana
Casa Karmenka

JUAN PLACIDO Hospedaje

JUAN PLACIDO Hospedaje
1.0 star property
Santa Ana
The price is HK$467
HK$467 total
1 Jan - 2 Jan 2026
JUAN PLACIDO Hospedaje

Ayenda Casa Escondida San Cristobal Premium

Ayenda Casa Escondida San Cristobal Premium
2.5 star property
San Cristóbal, 0.8 km from Santa Ana
8.8 out of 10, Excellent, (76)
"Good location and kind staff"
United States
ernesto
The price is HK$338
HK$338 total
8 Jan - 9 Jan 2026
Ayenda Casa Escondida San Cristobal Premium

Quechua Hotel cusco

Quechua Hotel cusco
3.5 star property
Cusco Historic Center, 0.7 km from Santa Ana
8.6 out of 10, Excellent, (84)
"Customer oriented Staff,cleanness great breakfast location "
United States
Eduardo
The price is HK$809
HK$809 total
5 Jan - 6 Jan 2026
Quechua Hotel cusco

Hotel Valle Andino

Hotel Valle Andino
3.0 star property
Cusco Historic Center, 1.2 km from Santa Ana
8.6 out of 10, Excellent, (87)
"Location is great breakfast is basic but good. The staff always endehavor to help us. Wifi was not the greatest when we were the "
Canada
Pascal
The price is HK$292
HK$292 total
8 Jan - 9 Jan 2026
Hotel Valle Andino

Quechua Plaza Hotel

Quechua Plaza Hotel
2.5 star property
Cusco Historic Center, 1.2 km from Santa Ana
9.6 out of 10, Exceptional, (7)
"Las habitaciones son súper acogedoras, con alfombra y calefacción que hacen que todo sea muy cómodo.Ademas tuvimos agua caliente durante toda nuestra estadía El desayuno buffet es delicioso y cada día sorprenden con un platito de fondo distinto 🤩. El personal es muy amable y siempre atento; incluso el mismo administrador, el joven Jesús Navia, nos atendió personalmente y desde el primer momento nos hizo sentir como en casa. ¡Definitivamente volvería sí o síii! 🙌✨"
Mexico
Dayanne Stephannie
The price is HK$1,138
HK$1,138 total
5 Jan - 6 Jan 2026
Quechua Plaza Hotel

Estancia San Pedro Hotel

Estancia San Pedro Hotel
3.0 star property
Cusco Historic Center, 0.7 km from Santa Ana
8.8 out of 10, Excellent, (93)
"Good hotel, I would stay again."
United States
Melanie
The price is HK$438
HK$438 total
11 Jan - 12 Jan 2026
Estancia San Pedro Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Cusco Historic Center

Cusco Historic Center is known for its popular shops, and with sights like Santa Catalina Convent and Coricancha, you won't get bored spending a day wandering around this part of Cusco.

San Blas

Take a walk through the heart of Cusco’s artisan district, one of the city’s most beguiling and lively areas.

San Cristóbal

While visiting San Cristóbal, you might make a stop by sights like Plaza Sán Cristobal and Museo de Arte Precolombino.

Santa Monica

While Santa Monica may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Real Plaza Cusco and Ttio Market.

Santiago

If you're looking for some top things to see and do in Santiago and surrounding area, you can visit Ttio Market and Santiago Plaza.

Top Santa Ana Hotel Reviews

Frequently asked questions

What is Santa Ana like?
Travellers to Cusco's Santa Ana neighbourhood will be sure to enjoy a stay here.
What's a favourite place to stay in Santa Ana?
Based on Expedia customer reviews, Hilton Garden Inn Cusco is the highest ranked property in Santa Ana. This hotel is a short 11-minute walk from Plaza de Armas, and it offers 2 bars and a restaurant. Another favourite option in the neighbourhood is Tierra Viva Cusco Saphi.
How many hotels should I expect to find in the Santa Ana area?
If you're searching for places to stay in Cusco, Expedia has something to meet your needs with 41 Santa Ana hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes, the majority of hotel reservations are fully refundable if cancelled before the hotel's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you have a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to view top deals in Santa Ana.
What can I see and do in this Cusco neighbourhood?
A few places to visit in the area around Santa Ana include Museo Irq'i Yachay, Museo de Plantas Sagradas Magicas y Medicinales and San Francisco Church Museum and Catacombs. Museum of Contemporary Art and ChocoMuseum are also worth a visit when you're out sightseeing in Cusco.