Best Santa Cruz Hotels in 2026 from HK$209 - Fully Refundable Options

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Our top choices for Santa Cruz hotels

Airport shuttle included

1. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Santa Cruz

imilse de

HK$577 total

9 Aug - 10 Aug

2. Hotel Cortez

Santa Cruz

Sarinela

HK$932 total

8 Aug - 9 Aug

3. Sun Hotel

Santa Cruz

JACK

HK$847 total

6 Aug - 7 Aug

4. Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Santa Cruz

Andrew

HK$993 total

24 Aug - 25 Aug

5. Camino Real Hotel

Santa Cruz

Austin

HK$1,138 total

3 Sept - 4 Sept

6. Chairú Eco Hotel

Santa Cruz

marcia

HK$423 total

8 Aug - 9 Aug

7. Lido Hotel

Santa Cruz

Gabrielle

HK$297 total

9 Aug - 10 Aug

8. Ibis Santa Cruz DE LA Sierra

Santa Cruz

Sarinela

HK$279 total

20 Aug - 21 Aug

Outdoor pool, open 9:00 AM to 8:00 PM, pool loungers

9. Premium Suites Deluxe Aparthotel Equipetrol

Santa Cruz

Luisa

HK$315 total

18 Aug - 19 Aug

Outdoor pool, pool umbrellas, pool loungers

10. Marriott Santa Cruz de la Sierra Hotel

Santa Cruz

Deivis

HK$830 total

15 Aug - 16 Aug

11. Delfines Collection Hotel By Mercure

Santa Cruz

ALEJANDRO

HK$374 total

21 Aug - 22 Aug

Egyptian cotton sheets, premium bedding, pillow-top beds, minibar

12. HOTEL OSHO

Santa Cruz

David

HK$483 total

15 Aug - 16 Aug

13. TRYP by Wyndham Santa Cruz

Santa Cruz

Pluetina

HK$769 total

6 Aug - 7 Aug

14. Hotel LP Equipetrol

Santa Cruz

Ricardo

HK$383 total

10 Aug - 11 Aug

15. Novotel Santa Cruz De La Sierra

Santa Cruz

ERNESTO

HK$1,040 total

24 Aug - 25 Aug

1 bedroom, in-room safe, desk, iron/ironing board (on request)

16. Apart Hotel Premium Suites Santa Cruz

Santa Cruz

Ruben

HK$212 total

8 Aug - 9 Aug

17. Hotel Las Américas

Santa Cruz

Stanley

HK$271 total

5 Aug - 6 Aug

18. Swissôtel Santa Cruz De La Sierra

Santa Cruz

GONZALO

HK$1,161 total

19 Aug - 20 Aug

Minibar, in-room safe, desk, soundproofing

19. Cosmopolitano Hotel Boutique

Santa Cruz

Heidi

HK$464 total

22 Aug - 23 Aug

Premium bedding, down duvets, minibar, blackout curtains

20. Hotel G

Santa Cruz

JACOB

HK$164 total

2 Sept - 3 Sept

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Holiday Rentals in Santa Cruz

Aparthotel

Premium Suites Deluxe Aparthotel Equipetrol

Santa Cruz

"great place to stay!"

Apartment

Apart Hotel Premium Suites Santa Cruz

Santa Cruz

"Great location."

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Where to stay in Santa Cruz

Find the best Santa Cruz areas for the activities you enjoy most. Learn more about Santa Cruz

Hamacas

Hamacas

When in Hamacas, you can plan a visit to Santa Cruz Zoo and Las Brisas Shopping Center, some noteworthy sights in the nearby area.

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Stay near popular Santa Cruz attractions

A historic building with arched windows and a clock. People are sitting and standing on the steps in front of the building.

Plaza 24 de Septiembre

8.8/10 (164 reviews)

Plaza 24 de Septiembre buzzes with local culture beneath swaying palms and colonial architecture. Climb the Cathedral's bell tower for spectacular city views while sampling authentic Bolivian coffee from vendors.

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Learn more about Santa Cruz

Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

See all hotels in Santa Cruz

A colonial-style building with a bell tower, palm trees, and a paved walkway.

Top Santa Cruz Hotel Reviews

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

10/10 Excellent

"Great hotel, breakfast was delicious. Would come back again."

Sun Hotel

8/10 Good

"The transfer from the airport is a bit tricky, look for a guy with a black polo and an orange logo… once in the hotel if you arrive late the kitchen might not be working and there are few options to have late dinner. The room was very spacious and clean, I had a great night sleep but it took around 40 minutes for the AC to cool the whole space as the room is extremely big and they don’t run the A/C 24/7… Breakfast was basic and the hot options were cold, but as I was hungry I was able to have some breakfast. Transfer back to the airport is every hour but they run an exception for me and took me at 11:30am. Overall really nice to have a one night stay to transfer from local to international flights in Santa Cruz if you need a lay over"

Alfonsina Hotel Boutique by Inboccaluppo

10/10 Excellent

"Good hotel. Very contemporary; buffet breakfast included. We walked to the old part of the city/cathedral - probably about 40 minutes walk but can stop for a coffee along the way! Restaurant and bar in hotel. Hotel also close to many other restaurants/bars"

More cheap stays in Santa Cruz

Ibiza Hostel

445 Santa Cruz Departamento de Santa Cruz

HK$99

HK$209 total

6 Aug - 7 Aug

Frequently asked questions

What's the best place for a stay in Santa Cruz?

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is one of the top choices for your stay based on our traveller data. This hotel offers a full-service spa and 2 restaurants. Other good choices for your stay include Ibis Santa Cruz DE LA Sierra and Marriott Santa Cruz de la Sierra Hotel. See all available top hotels, or vacation rentals in Santa Cruz.

What are some of the best holiday rentals that Santa Cruz has to offer?

Casa Vida: This highly rated holiday home rental in Santa Cruz is located in a rural location, and has an outdoor pool, a patio and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a full-sized fridge, a stovetop and a microwave, so that you can cook with friends or family. Kick off your shoes and enjoy yourself with a private garden and a selection of games. Some other homes for rent in Santa Cruz include Cozy 1-bedroom house in beautiful Santa Cruz de la Sierra with WiFi, AC and Seasonal House. See all vacation rentals in Santa Cruz.

If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?

Yes! You'll find that most hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.

What's the best budget-friendly accommodation in Santa Cruz?

Based on our traveller reviews, Ibiza Hostel is a top choice for a less expensive stay. Other choices for your budget-friendly stay include residencial francia - Hostel and Residencial Ikandire II. View all budget hotels in Santa Cruz.

What's the best family accommodation in Santa Cruz?

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a hotel with 2 restaurants and free parking, and it's a top choice on Expedia for families. Other choices for your child-friendly holiday include Marriott Santa Cruz de la Sierra Hotel and Camino Real Hotel. Also, attractions such as Santa Cruz Zoo and Play Land Amusement Park are fun for children of all ages. Find more child-friendly accommodations in Santa Cruz.

What's the best LGBTQ-friendly accommodation in Santa Cruz?

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. Swissôtel Santa Cruz De La Sierra and Radisson Hotel Santa Cruz are other good choices for your holiday. See all available hotels listed as LGBTQ-friendly in Santa Cruz.

What's the best dog-friendly accommodation option in Santa Cruz?

Casa Por Temporadas is a top dog-friendly guest house, and offers an outdoor pool along with in-room kitchens for its human guests. Two other good options for you and your pet's trip include Ibis Santa Cruz DE LA Sierra and Swissôtel Santa Cruz De La Sierra. See more pet-friendly hotel accommodations in Santa Cruz.

What's the best luxury accommodation option in Santa Cruz?

Marriott Santa Cruz de la Sierra Hotel is a luxury hotel with a full-service spa and a rooftop terrace, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Camino Real Hotel and Novotel Santa Cruz De La Sierra are other upscale choices for your holiday. Find more luxury hotels in Santa Cruz.

What are some accommodation options with pools in Santa Cruz?

Yotau All Suites Hotel is a top hotel with 2 outdoor swimming pools, a children's pool and 2 restaurants. A couple of other options that feature an on-site pool include Buganvillas Hotel Suites & Spa and Loft sobrio, rooftop panorámico y piscina infinita. View all hotels with pools in Santa Cruz.

What is the best spa hotel in Santa Cruz?

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a top spa hotel featuring a fitness centre, a hair salon and a bar. Enjoy a facial, body scrub or hydrotherapy at Los Tajibos Club Spa. Other popular spa hotels in Santa Cruz include Marriott Santa Cruz de la Sierra Hotel and Camino Real Hotel. See all spa hotels in Santa Cruz.

What's it like to stay in Santa Cruz?

Visitors to Santa Cruz will definitely enjoy the shopping. Tourists can also enjoy the city's cafés, zoo and cathedral. In Santa Cruz, there are 292 hotels and other accommodation options to choose from. Find out more about Santa Cruz.

What is there to see in Santa Cruz?

Cultural venues include Cine Center, Ethno-folkloric Museum and Sacred Art Museum. Landmarks like San Lorenzo Cathedral, Plaza 24 de Septiembre and Blacutt Square might be worth a visit. Natural beauty is on display at Arenal Park, Guembe Biocenter and Lomas de Arena Regional Park. Take a look at what more there is to see and do in Expedia's Santa Cruz guide.

How should I get around Santa Cruz?

If you want to venture outside the area, hop on a train at Santa Cruz de la Sierra Station. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.

What's the weather like in Santa Cruz?

The hottest months are usually October and November, with an average temperature of 26°C, while the coldest months are June and July, with an average of 21°C. Average annual precipitation for Santa Cruz is 1208 mm.

Santa Cruz hotels from HK$209

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Our top choices for Santa Cruz hotels

1. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

2. Hotel Cortez

3. Sun Hotel

4. Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

5. Camino Real Hotel

6. Chairú Eco Hotel

7. Lido Hotel

8. Ibis Santa Cruz DE LA Sierra

9. Premium Suites Deluxe Aparthotel Equipetrol

10. Marriott Santa Cruz de la Sierra Hotel

11. Delfines Collection Hotel By Mercure

12. HOTEL OSHO

13. TRYP by Wyndham Santa Cruz

14. Hotel LP Equipetrol

15. Novotel Santa Cruz De La Sierra

16. Apart Hotel Premium Suites Santa Cruz

17. Hotel Las Américas

18. Swissôtel Santa Cruz De La Sierra

19. Cosmopolitano Hotel Boutique

20. Hotel G

Holiday Rentals in Santa Cruz

Premium Suites Deluxe Aparthotel Equipetrol

Where to stay in Santa Cruz

Hamacas

Stay near popular Santa Cruz attractions

Plaza 24 de Septiembre

Learn more about Santa Cruz

Top Santa Cruz Hotel Reviews

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

More cheap stays in Santa Cruz

Ibiza Hostel

Frequently asked questions

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