Kid friendly Holidays in Southwest Houston 2026

Plan, book, travel with confidence
Better together
Save up to HK$7,200 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place

SpringHill Suites Houston Medical Center/NRG Park

1400 Old Spanish Trl Houston TX

20 min walk from MD Anderson Cancer Center

Stay at this business-friendly hotel in Houston. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...

Hyatt Place Houston/Galleria

5252 W. Alabama Houston TX

5 min drive from MD Anderson Cancer Center

Stay at this business-friendly hotel in Houston. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the breakfast and the helpful staff in ...

8.8/10 Excellent! (1,642 reviews)

"Generally fine - the bathrooms need updating but they were clean."

Reviewed on 29 Sept 2026

DoubleTree by Hilton Houston Medical Center Hotel & Suites

6800 Main Street Houston TX

2 min walk from MD Anderson Cancer Center

Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, breakfast (surcharge) and a free local area shuttle. Our guests praise the helpful staff in ...

See all 1,293 properties in Southwest Houston

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.