Luxury Holidays in Central Missouri 2026

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Ramada by Wyndham Columbia

901 Conley Rd Columbia MO

2 hours drive from Lake of the Ozarks

Stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...

7.6/10 Good! (1,001 reviews)

"Paid for my room, tried to call to make sure my reservation was made properly and to ask that they make sure the tub was cleaned properly and it was near impossible to reach them by phone. I had to go into my email to call a different number that was provided and the connection was so bad and the ..."

Reviewed on 16 Sept 2026

voco The Tiger Hotel Columbia, MO by IHG

23 S 8th St Columbia MO

2 hours drive from Lake of the Ozarks

Stay at this business-friendly hotel in Columbia. Enjoy free Wi-Fi, 4 restaurants and 3 bars/lounges. Our guests praise the helpful staff and the property condition ...

9/10 Wonderful! (1,001 reviews)

"My favorite hotel stay in Colombia."

Reviewed on 14 Sept 2026

Lodge Of Four Seasons Golf Resort, Marina & Spa

315 Four Seasons Dr. Lake Ozark MO

20 min drive from Lake of the Ozarks

Stay at this beach resort in Lake Ozark. Enjoy free Wi-Fi, an outdoor pool and a full-service spa. Our guests praise the pool and the helpful staff in their ...

7.4/10 Good! (1,330 reviews)

"Me gustó mucho"

Reviewed on 14 Sept 2026

See all 5,177 properties in Central Missouri

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.