Luxury Holidays in Central Missouri 2026

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Ramada by Wyndham Columbia

901 Conley Rd Columbia MO

2 hours drive from Lake of the Ozarks

Stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...

voco The Tiger Hotel Columbia, MO by IHG

23 S 8th St Columbia MO

2 hours drive from Lake of the Ozarks

Stay at this business-friendly hotel in Columbia. Enjoy free Wi-Fi, 4 restaurants and 3 bars/lounges. Our guests praise the helpful staff and the property condition ...

9/10 Wonderful! (1,001 reviews)

"My favorite hotel stay in Colombia."

Reviewed on 14 Sept 2026

Lodge Of Four Seasons Golf Resort, Marina & Spa

315 Four Seasons Dr. Lake Ozark MO

20 min drive from Lake of the Ozarks

Stay at this beach resort in Lake Ozark. Enjoy free Wi-Fi, an outdoor pool and a full-service spa. Our guests praise the pool and the helpful staff in their ...

7.4/10 Good! (1,330 reviews)

"Me gustó mucho"

Reviewed on 14 Sept 2026

See all 5,177 properties in Central Missouri

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.