Edisto Island Edisto Island Serpentarium Hotels: 2026 Limited-Time Hotel Deals @Expedia

Our top choices for Edisto Island Serpentarium hotels

Charleston Kiawah Island/Andell Inn

13.4 km from Edisto Island Serpentarium

Jack

HK$3,585 total

includes taxes & fees

2 Aug - 3 Aug

The Dunlin, Auberge Collection

16.4 km from Edisto Island Serpentarium

Sandi

HK$4,245 total

includes taxes & fees

28 Jul - 29 Jul

On the beach, sun-loungers, beach umbrellas, beach towels

The Sanctuary at Kiawah Island Golf Resort

18.2 km from Edisto Island Serpentarium

Jonathan

HK$6,558 total

includes taxes & fees

19 Jul - 20 Jul

Tide Timber - A Premiere Stay On Seabrook

12.1 km from Edisto Island Serpentarium

Shakoka

HK$7,559 total

includes taxes & fees

8 Jul - 9 Jul

Hideout at Shipwatch - On The Beach

15.3 km from Edisto Island Serpentarium

HK$3,901 total

includes taxes & fees

8 Jul - 9 Jul

The Breeze in Seabrook Island

9.9 km from Edisto Island Serpentarium

HK$6,393 total

includes taxes & fees

12 Jul - 13 Jul

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Top Edisto Island Serpentarium Hotel Reviews

Edisto Deep Water - Dock and Boat Ramp - Recently Renovated - 40-acres

10/10 Excellent

"Endless Views is very beautiful! The name is perfect! We needed the owner once during our stay and they helped us immediately! Great place to relax!"

Water Front Edisto with Private Dock On Deep Creek overlooking the Ocean

10/10 Excellent

"Wonderful week in Edisto. The house was perfect and our family thoroughly enjoyed our stay! The views, the porch and the space was just right! The Host was so helpful before and during our stay to answer questions and give suggestions! She was amazing! We will certainly look at going back. Highly recommend!"

Gorgeous Secluded Island W/Creek & Ocean View w/DOCK & swim! Pet-friendly/Wi-Fi

10/10 Excellent

"I loved this property. Very quiet and secluded with awesome views. Sunrise and Sunset can be watched at the dock. If you are a bird watcher, it is a haven of unusual birds. I saw a Painted Bunting, (male and female) visiting their feeders...a lot of woodpeckers, Roseate spoonbills and the best of all...A Whooping Crane.. The beach across the marsh is great for shelling, and the neighbors saw two turtles come up and lay their eggs at about 8:30-9:15 pm. Mike was great to communicate with and the history of the house and the Lumpkins is fun to read about...I will come back."

Partial OCEAN VIEW! Fenced yard bring doggo. WaterFront DOCK Fishing

10/10 Excellent

"First of all I must say all my family (15 of us) had an absolutely fantastic time and the beach house (Shark Shack) was a big part of that. All the bedrooms and bathrooms were great as well the kitchen space and general lay-out. The yard was great and the fishing lagoon (grandboys) was a huge extra (along with the dock (although small dock). The fenced in yard for our fur-babies a great addition as well. Greatly enjoyed our stay and would certainly return to this house. We receive a Blessing from the Good Lord every year our family is together at Edisto Beach !!! Thank you."

The Marshpad, surrounded by nature, mins to beach in gated community

10/10 Excellent

"We have visited Edisto for years, but this home by far was our favorite! The location, room in the home and simply everything was PERFECT! Danny responded to any question we had quickly. This truly was a great week!"

Misty Lane: Lowcountry Paradise Near Beach & State Park; Game Room; Cable/WiFi

10/10 Excellent

"My family had a very pleasant stay in this home. It is a very large home with plenty of room for our family of 8 and could accommodate a few more.The family pets enjoyed the screen in porch with a TV that kept them calm and the large yard to run around in. The grandchildren very much enjoyed pasting time in the game room. Many bathrooms and very clean. There was always someone near by with any questions that you may have."

Hotels near other Edisto Island Serpentarium attractions

Botany Bay Plantation

8.8/10 (25 reviews)

Explore the great outdoors at Botany Bay Plantation, a lovely green space in Edisto Island. Stroll along the beaches in this relaxing area or seek out the fishing spots.

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Frequently asked questions

What's the area like around Edisto Island Serpentarium?

Edisto Island Serpentarium is located in an area of Edisto Island known for its beautiful beaches. You'll find 191 hotels and other accommodations within a few miles for a convenient home base.

How many hotels are there near Edisto Island Serpentarium?

Expedia has 191 hotels and other accommodation options a few miles from Edisto Island Serpentarium.

If I need to cancel the hotel reservation for my stay near Edisto Island Serpentarium, will I receive a refund?

Yes! You'll find that most room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within 24 hours of booking. Enter your dates, click on "Search", then filter by "fully refundable" to get the best deals available near Edisto Island Serpentarium.

What can I see and do near Edisto Island Serpentarium?

Attractions like With These Hands Gallery and Edisto Island Museum highlight the local culture. You might plan a visit to Edisto Beach State Park or Botany Bay Plantation Heritage Preserve and Wildlife Management Area while you're in the area. You might also stop by Bohicket Marina, located 7.9 mi from Edisto Island Serpentarium, or Freshfields Village which is 8.3 mi away.

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Our top choices for Edisto Island Serpentarium hotels

Charleston Kiawah Island/Andell Inn

The Dunlin, Auberge Collection

The Sanctuary at Kiawah Island Golf Resort

Tide Timber - A Premiere Stay On Seabrook

Hideout at Shipwatch - On The Beach

The Breeze in Seabrook Island

Top Edisto Island Serpentarium Hotel Reviews

Edisto Deep Water - Dock and Boat Ramp - Recently Renovated - 40-acres

Water Front Edisto with Private Dock On Deep Creek overlooking the Ocean

Discover 5 Acres of Secluded Luxury on the Marsh and Close to the Beach: Edisto

Gorgeous Secluded Island W/Creek & Ocean View w/DOCK & swim! Pet-friendly/Wi-Fi

The Gulls Nest Beach House

Partial OCEAN VIEW! Fenced yard bring doggo. WaterFront DOCK Fishing

The Marshpad, surrounded by nature, mins to beach in gated community

Beach Access, Steps Away | Seaclusion by AvantStay

Misty Lane: Lowcountry Paradise Near Beach & State Park; Game Room; Cable/WiFi

Hotels near other Edisto Island Serpentarium attractions

Botany Bay Plantation

With These Hands Gallery

Botany Bay Plantation Heritage Preserve and Wildlife Management Area

Edisto Island Museum

Edisto Beach State Park

beach near Spinnaker Beachhouses

Plantation Course at Edisto

Deep Water Vineyard

Frequently asked questions