South Central Houston
Houston
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Top hotels in South Central Houston
Hotel Zaza Houston Museum District
This was a good, hotel in a great district with some very nice amenities. The staff are lovely and the shuttle is fantastic. I didn’t use the pool or spa so can’t speak to this. The rooms are not as luxury boutique as I was expecting but they were certainly comfortable, just a bit in need of renovation- ...
Reviewed on 6 Apr 2026
Hilton Houston Plaza/Medical Center
Nice place and coming back
Reviewed on 8 Apr 2026
InterContinental Houston by IHG
Very impressed by the Hotel and price
Reviewed on 7 Apr 2026
The Westin Houston Medical Center/Museum District
Wonderful stay near the medical center. Staff went above and beyond. I was initially ignored by several staff, but overall great stay.
Reviewed on 7 Apr 2026
DoubleTree by Hilton Houston Medical Center Hotel & Suites
The lady at the breakfast buffet is wonderful. She's so friendly and helpful, perfect for the job!
Reviewed on 7 Apr 2026
Americas Best Value Inn Medical Center Downtown
Positive experience across the board.
Reviewed on 5 Apr 2026
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Other neighbourhoods around South Central Houston
Greater Third Ward
If you're spending time in Greater Third Ward, check out sights like Barbara Jordan & Mickey Leland Archives or Fertitta Center and hop on the metro to see more of the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.
Midtown
Midtown is well liked for its restaurants and live music. If you're hoping to get in some sightseeing, Houston Fire Museum and Midtown Arts and Theater Center Houston are top spots, and you can jump on the metro at McGowen Station or Ensemble/HCC Station to get around.
East Downtown Houston
The restaurants and live music are just a few things visitors like about East Downtown Houston. Shell Energy Stadium and Giant Beatles Statues are worthwhile spots to check out, and you can hop on the metro at Leeland/Third Ward Station or EaDo/Stadium Station to get around the larger area.
Museum District
Known for its abundant dining options and interesting museums, there's plenty to explore in Museum District. Top attractions like Children's Museum of Houston and Houston Natural Science Museum are major draws, and you can catch the metro at Museum District Station or Hermann Park/Rice U Station to see more of the city.
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.
Downtown Houston
Gourmet restaurants acclaimed theatres and top sights from Toyota Center to Daikin Park – discover Downtown Houston, a destination also famous for its sports teams.
