South Central Houston

Houston

A water feature with multiple tiers and a circular viewing platform at the top.
A city skyline at night with illuminated skyscrapers and a large brick plaza in the foreground.
A train on tracks with graffiti on a nearby building.
A park with a gazebo, a fountain, and tall buildings in the background.
A water feature with a cascading waterfall, a grassy hill, and a tall building in the background.

Stay near popular South Central Houston attractions

Things to do


Top hotels in South Central Houston

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
The price is HK$854 per night from 7 Nov to 8 Nov
HK$854
HK$1,008 total
7 Nov - 8 Nov
includes taxes & fees
Stay at this luxury hotel in Houston. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in their reviews. ...
Hilton Houston Plaza/Medical Center
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

4 out of 5
1709 DRYDEN ROAD Houston TX
The price is HK$1,261 per night from 25 Oct to 26 Oct
HK$1,261
HK$1,569 total
25 Oct - 26 Oct
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service and a 24-hour health club. Our guests praise the helpful staff and ...
The Westin Houston Medical Center/Museum District
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
The price is HK$1,647 per night from 18 Oct to 19 Oct
HK$1,647
HK$2,284 total
18 Oct - 19 Oct
includes taxes & fees
Stay at this luxury hotel in Houston. Enjoy free Wi-Fi, a full-service spa and breakfast (surcharge). Our guests praise the helpful staff in their reviews. Popular ...
Hotel Zaza Houston Museum District
InterContinental Houston by IHG

InterContinental Houston by IHG

4 out of 5
6750 Main St Houston TX
The price is HK$1,279 per night from 15 Nov to 16 Nov
HK$1,279
HK$1,653 total
15 Nov - 16 Nov
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, breakfast (surcharge) and a free local area shuttle. Our guests praise the helpful staff and ...
9.4/10 Exceptional! (1,010 reviews)
"Good"

Reviewed on 14 Oct 2026

InterContinental Houston by IHG
Extended Stay America Suites Houston Med Ctr Braeswood Bl

Extended Stay America Suites Houston Med Ctr Braeswood Bl

2.5 out of 5
1301 Braeswood Blvd Houston TX
The price is HK$607 per night from 18 Oct to 19 Oct
HK$607
HK$713 total
18 Oct - 19 Oct
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the clean rooms in their reviews. Popular ...
6.2/10 (1,002 reviews)
"Although carpet stains near an elevator were off-putting, corridor and room air was fresh and clean. Room windows open. Everything was clean enough and high contact areas were all very clean. The room could use detailing in a few areas: some corners, crevices of the sofa bed, refrigerator exterior, ..."

Reviewed on 16 Oct 2026

Extended Stay America Suites Houston Med Ctr Braeswood Bl
Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District

4 out of 5
6580 Fannin Street Houston TX
The price is HK$1,335 per night from 23 Oct to 24 Oct
HK$1,335
HK$1,816 total
23 Oct - 24 Oct
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), a free local area shuttle and room service. Our guests praise the helpful staff ...
9/10 Wonderful! (1,001 reviews)
"Always appreciate staying at this property when visiting MD Anderson - the staff is excellent, rooms are great, and the shuttle is especially helpful"

Reviewed on 15 Oct 2026

Houston Marriott Medical Center/Museum District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in South Central Houston

Find the best South Central Houston areas for the activities you enjoy most.

Downtown Houston

Gourmet restaurants acclaimed theatres and top sights from Daikin Park to Toyota Center – discover Downtown Houston, a destination also famous for its sports teams.

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

Texas Medical Center

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.



South Central Houston