Louisville Louisville Science Center Hotels: 2026 Limited-Time Hotel Deals @Expedia

The entrance to the Kentucky Science Center with a large circular structure in the foreground.

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Our top choices for Louisville Science Center hotels

A wooden staircase with a balustrade leading to a landing.

A two-story brick building with a white porch and a sign reading "Hotel".

A bedroom with a bed, a dresser, a television, and a desk with a lamp.

A dining area with brick walls, wooden shelves, and tables set for a meal.

1. Market Street Inn

2.1 km from Louisville Science Center

Holly

HK$1,381

HK$1,561 total

includes taxes & fees

22 Sept - 23 Sept

A modern hotel lobby with a reception desk, seating area, and a staircase leading to the upper floor.

A modern interior with a green wall, black chairs, and a ceiling with exposed beams and lights.

A modern, well-lit room with a large bed, a green sofa, a small round table, and a kitchen area in the background.

A modern bedroom with a bed, a blue sofa, a large rug, and a TV on the wall.

2. Stellar Suites

East Market District, 2.2 km from Louisville Science Center

Benton

HK$771

HK$1,305 total

includes taxes & fees

4 Oct - 5 Oct

A grand lobby with ornate columns, plush seating, and a chandelier.

A grand lobby with ornate ceiling, large windows, and classic furniture.

A grand dining area with ornate ceiling, chandeliers, and a bar area with a sign reading "Cigar Bar".

A grand lobby with ornate ceiling, multiple seating areas, and a staircase.

3. The Brown Hotel

Downtown Louisville, 1.2 km from Louisville Science Center

Melanie

HK$1,112

HK$1,308 total

includes taxes & fees

20 Sept - 21 Sept

A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.

A room with a large mirror, a wooden dresser, a red patterned rug, and a door with a wreath.

An outdoor patio with red furniture, including a table and chairs, and two red umbrellas providing shade.

A room with a red velvet sofa, a blue armchair, and a small round table with books.

4. DuPont Mansion Bed & Breakfast

Old Louisville, 2.8 km from Louisville Science Center

Casey

HK$1,429

HK$1,659 total

includes taxes & fees

20 Sept - 21 Sept

A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.

A modern restaurant interior with a staircase, round tables, and a brick wall.

A multi-level interior with a staircase, bookshelves, and a prominent sign reading "THE GRADY".

A building with a sign reading "THE GRADY" at the entrance.

5. The Grady

Downtown Louisville, 0.2 km from Louisville Science Center

Bruce

HK$1,371

HK$1,613 total

includes taxes & fees

11 Oct - 12 Oct

A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.

A spacious hotel lobby with a central seating area, stone accent walls, and a chandelier.

A spacious lobby with a large seating area, a chandelier, and a patterned rug.

A modern hotel with multiple floors, large windows, and a prominent sign for Homewood Suites.

6. Homewood Suites by Hilton Louisville Downtown, KY

Downtown Louisville, 0.2 km from Louisville Science Center

Steve

HK$1,086

HK$1,278 total

includes taxes & fees

12 Oct - 13 Oct

A classical gold statue in front of a multi-story building with large windows and a brick facade.

A cozy room with a geometric-patterned ceiling, a sofa, and a chair.

A cozy room with wooden walls, a table with a lamp, and shelves displaying books and decorative items.

7. 21c Museum Hotel Louisville

Downtown Louisville, < 0.1 km from Louisville Science Center

Candice

HK$1,460

HK$1,757 total

includes taxes & fees

11 Oct - 12 Oct

A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.

A lobby with a marble floor, a reception desk, and a large chandelier.

A rooftop bar with outdoor seating, including sofas and chairs, and a bar area with a television screen.

A modern building entrance with a glass facade, wooden ceiling, and illuminated fixtures.

8. Omni Louisville Hotel

Downtown Louisville, 0.8 km from Louisville Science Center

Kara

HK$2,190

HK$2,577 total

includes taxes & fees

30 Sept - 1 Oct

An outdoor terrace with tables and chairs, large windows, and a view of the city skyline at sunset.

A modern hotel lobby with a brick wall, grey sofas, a coffee table, and a large TV screen displaying "TEMPO by Hilton".

A modern hotel lobby with a reception desk, seating area, and a large abstract ceiling artwork.

A modern restaurant with high tables and booths, wooden ceiling panels, and framed pictures on the walls.

9. Tempo By Hilton Louisville Downtown Nulu

Phoenix Hill, 2.1 km from Louisville Science Center

Maria

HK$1,210

HK$1,424 total

includes taxes & fees

6 Oct - 7 Oct

An outdoor seating area with sofas and tables, a fire feature, and a clock tower in the background.

A modern hotel room with a large bed, a city view, and a unique headboard design.

A modern living room with a sofa, a coffee table, a side table with a plant, and a view of a building with a clock tower.

A hotel with a prominent sign, a central courtyard with a sculpture, and a dome structure in the background.

10. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Downtown Louisville, 0.8 km from Louisville Science Center

Breeana

HK$1,859

HK$2,187 total

includes taxes & fees

11 Oct - 12 Oct

A modern bar area with a circular bar, multiple seating options, and a large screen.

A spacious indoor area with a large dining table, multiple chairs, a fireplace, and a kitchen area with a bar.

A modern living room with a sectional sofa, a small table, and a floor lamp. Large windows offer a view of a cityscape and a building with glass windows.

A modern lobby with a fireplace, seating area, and a reception desk.

11. Cambria Hotel Louisville Downtown-Whiskey Row

Downtown Louisville, 1.2 km from Louisville Science Center

Hallie

HK$935

HK$1,100 total

includes taxes & fees

18 Oct - 19 Oct

An outdoor seating area with wicker furniture and a fire pit.

A modern lounge area with seating, tables, and a view of the city through large windows.

An indoor swimming pool with clear water, a diving board, and lounge chairs around the pool area.

A modern living room with a sofa, armchairs, a coffee table, and a TV.

12. Towneplace Suites By Marriott Louisville Downtown

Downtown Louisville, 0.3 km from Louisville Science Center

Scott

HK$957

HK$1,126 total

includes taxes & fees

11 Oct - 12 Oct

A bar area with a neon 'CHECK IN' sign, a variety of liquor bottles, and a modern seating arrangement.

A modern hotel with a prominent 'Marriott' sign, large windows, and a brick facade.

A cozy living room with a fireplace, a black leather sofa, and a patterned rug.

A modern living room with a sofa, ottomans, a coffee table, and a rug.

13. Moxy Louisville Downtown

Downtown Louisville, 0.9 km from Louisville Science Center

Harry

HK$1,004

HK$1,181 total

includes taxes & fees

4 Oct - 5 Oct

An indoor dining area with wooden tables and chairs, a bar area, and a view of the street outside.

A modern coffee shop interior with a central island, wooden counter, and large windows.

A modern hotel with a prominent 'Aloft Hotels' sign, multiple floors, and a corner location with a view of the city skyline.

A modern lounge area with a pool table, comfortable seating, a fireplace, and a brick accent wall.

14. Aloft by Marriott Louisville Downtown

Downtown Louisville, 0.9 km from Louisville Science Center

Angela

HK$1,063

HK$1,251 total

includes taxes & fees

4 Oct - 5 Oct

A modern bar area with a marble countertop, seating, and a central bar stocked with bottles.

A modern hotel lobby with a reception desk, seating area, and a large window providing natural light.

A modern hotel building with a prominent AC Hotel NULU sign, multiple floors, and a well-lit entrance.

A modern restaurant with high ceilings, large windows, and a mix of round and rectangular tables.

15. AC Hotel Louisville Downtown

East Market District, 2.1 km from Louisville Science Center

Connie

HK$1,158

HK$1,362 total

includes taxes & fees

4 Oct - 5 Oct

A room with a checkered floor, leather armchairs, a sofa, and a small table with a glass. There are windows with arched tops and a view of buildings outside.

A bedroom with a bed, a chair, a TV, and a window with curtains.

A bar area with a wooden bar counter, two stools, a chandelier, and a mirror.

A yellow coffee shop counter with a menu board above, displaying various coffee and food items.

16. Hotel Genevieve part of JdV by Hyatt

East Market District, 2.1 km from Louisville Science Center

Rebekah

HK$1,192

HK$1,403 total

includes taxes & fees

4 Oct - 5 Oct

A covered patio with a stone wall, a glass table, and a bench.

A garden pathway with a lantern, potted plants, and a white fence.

A grand room with a fireplace, a staircase, and a chandelier.

A stone house with a balcony, a front door, and a staircase leading to the entrance.

17. Central Park Bed & Breakfast

Old Louisville, 3 km from Louisville Science Center

Angie

HK$1,340

HK$1,555 total

includes taxes & fees

21 Sept - 22 Sept

A modern interior with large windows offering a city view, a circular light fixture, and leather seating.

A modern bar with a long counter, multiple shelves of liquor bottles, and cushioned bar stools.

A spacious room with a large dining table, comfortable seating, a sofa, and a view of a bridge.

A nighttime view of The GALT and The Galthouse buildings with illuminated signage, a busy street with light trails from moving vehicles, and a modern urban setting.

18. Galt House Hotel Trademark Collection by Wyndham

Downtown Louisville, 0.5 km from Louisville Science Center

Jacob

HK$1,274

HK$1,499 total

includes taxes & fees

4 Oct - 5 Oct

A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.

A modern hotel room with a living area, a dining area, and a bedroom.

A modern bar area with a long counter, multiple chairs, and a bookshelf filled with bottles.

A hotel dining area with long tables, booths, and a bar.

19. Embassy Suites Louisville Downtown

Downtown Louisville, 0.8 km from Louisville Science Center

Maurica

HK$1,280

HK$1,506 total

includes taxes & fees

22 Sept - 23 Sept

A modern building with a restaurant on the ground floor, featuring large windows and outdoor seating.

A modern hotel room with a large window offering a city view, a cozy seating area with a sofa and chairs, a dining table with lamps, and a wooden floor.

A reception area with marble counters, modern pendant lighting, and potted orchids.

A modern bar area with glass partitions, bar stools, and a variety of bottles.

20. Louisville Marriott Downtown

Downtown Louisville, 0.8 km from Louisville Science Center

Jacobi

HK$1,680

HK$1,977 total

includes taxes & fees

4 Oct - 5 Oct

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Compare popular hotels close to Louisville Science Center

Property	Property class	Guest rating
Market Street Inn	9.8 Exceptional 124 reviews	View
Stellar Suites	9.6 Exceptional 150 reviews	View
The Brown Hotel	9.4 Exceptional 1,307 reviews	View
DuPont Mansion Bed & Breakfast	9.6 Exceptional 146 reviews	View
The Grady	9.4 Exceptional 1,001 reviews	View

Top Louisville Science Center Hotel Reviews

The Brown Hotel

10/10 Excellent

"Great place to stay"

Holiday Inn Louisville Downtown by IHG

10/10 Excellent

"Great location and not a bad hotel for price. But the parking is $30.00 a night. Everyone is nice though."

Hyatt Regency Louisville

10/10 Excellent

"Very clean, quiet and helpful staff. Close to convention centre and restaurants."

Cambria Hotel Louisville Downtown-Whiskey Row

10/10 Excellent

"The staff was very helpful"

Moxy Louisville Downtown

10/10 Excellent

"Was a great place and great experience with the staff. Highly recommend this place"

SpringHill Suites by Marriott Louisville Downtown

10/10 Excellent

"Our room was clean and spacious. The staff were nice and helpful."

Louisville Marriott Downtown

10/10 Excellent

"Great stay"

Embassy Suites Louisville Downtown

10/10 Excellent

"Great location! Breakfast was better than expected with an omelette station. Loved the convenience of the airport shuttle. Only complaint was where the TV was on the wall and the position of the bed."

The PRES@The 713! Penthouse Suite with private rooftop patio, on Bourbon Trail!

10/10 Excellent

"Wonderful experience from making the reservation until the end of our stay. Great communication with the hosts. And enjoyed the location and the loft was very comfortable."

Other attractions near Louisville Science Center

A wall of wooden baseball bats organized by size and weight.

Louisville Slugger Museum

9.2/10 (2,299 reviews)

Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.

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A modern building with a cylindrical structure and a glass facade.

Muhammad Ali Center

8.8/10 (295 reviews)

One of the world’s greatest boxers continues providing inspiration beyond the world of sport. Understand this superstar by visiting this center honoring him.

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The Frazier History Museum with red doors and a tree in front.

Frazier International History Museum

9.4/10 (10 reviews)

Get to know Louisville with a visit to this esteemed museum. It’s a great spot for social interaction as well.

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Kentucky Center for the Performing Arts

8.8/10 (49 reviews)

Enjoy a pleasant night at the opera or attend a concert, live dance or stage production at this glass-fronted venue in downtown Louisville.

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Kentucky Museum of Art and Craft

You can spend an afternoon exploring the galleries in Kentucky Museum of Art and Craft during your trip to Louisville. Stroll along the area's riverfront or experience its lively festivals.

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Golden Statue of David

Find out about the history of Louisville when you spend time at Golden Statue of David. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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SAR Genealogical Research Library: NSSAR Library

You can spend time exploring the galleries in SAR Genealogical Research Library: NSSAR Library in Louisville. Amble around this family-friendly area's riverfront and enjoy its top-notch restaurants.

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Louisville Glassworks

You can spend an afternoon browsing the exhibits at Louisville Glassworks in Louisville. Experience the area's lively festivals or attend a sporting event.

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Frequently asked questions

What's the area like around Louisville Science Center?

Louisville Science Center is located in an area of Louisville known for its stunning river views, sporting events and great live music scene. If you're looking for a convenient place to stay, take a look at the 292 hotels and other accommodation options you'll find within a mile.

Where is the best place to stay near Louisville Science Center?

Adjacent to Louisville Science Center, Holiday Inn Express & Suites Louisville Downtown by IHG is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a 24-hour fitness centre. Other good choices within a short distance include Galt House Hotel Trademark Collection by Wyndham and Omni Louisville Hotel.

How many hotels can I expect to find close to Louisville Science Center?

Expedia has 292 hotels and other accommodation options within a mile from Louisville Science Center.

If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?

Yes! Most hotel room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to get the top deals on offer near Louisville Science Center.

What can I see and do near Louisville Science Center?

21c Museum Hotel, Louisville Slugger Museum and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row and Historic Frankfort Avenue. You can catch a show at Louisville Palace, Derby Dinner Playhouse and Headliners Music Hall.

Louisville Louisville Science Center Hotels

Change your mind

Treat yourself

Be picky

Check prices for these dates

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Star rating

Guest rating

Our top choices for Louisville Science Center hotels

1. Market Street Inn

2. Stellar Suites

3. The Brown Hotel

4. DuPont Mansion Bed & Breakfast

5. The Grady

6. Homewood Suites by Hilton Louisville Downtown, KY

7. 21c Museum Hotel Louisville

8. Omni Louisville Hotel

9. Tempo By Hilton Louisville Downtown Nulu

10. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

11. Cambria Hotel Louisville Downtown-Whiskey Row

12. Towneplace Suites By Marriott Louisville Downtown

13. Moxy Louisville Downtown

14. Aloft by Marriott Louisville Downtown

15. AC Hotel Louisville Downtown

16. Hotel Genevieve part of JdV by Hyatt

17. Central Park Bed & Breakfast

18. Galt House Hotel Trademark Collection by Wyndham

19. Embassy Suites Louisville Downtown

20. Louisville Marriott Downtown

Compare popular hotels close to Louisville Science Center

Top Louisville Science Center Hotel Reviews

The Brown Hotel

Holiday Inn Louisville Downtown by IHG

Hyatt Regency Louisville

Cambria Hotel Louisville Downtown-Whiskey Row

Moxy Louisville Downtown

SpringHill Suites by Marriott Louisville Downtown

Louisville Marriott Downtown

Embassy Suites Louisville Downtown

The PRES@The 713! Penthouse Suite with private rooftop patio, on Bourbon Trail!

Other attractions near Louisville Science Center

Louisville Slugger Museum

Muhammad Ali Center

Frazier International History Museum

Kentucky Center for the Performing Arts

Kentucky Museum of Art and Craft

Golden Statue of David

SAR Genealogical Research Library: NSSAR Library

Louisville Glassworks

Frequently asked questions