Jacksonville Mayo Clinic Florida Hotels

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Check prices for these dates

Tonight
12 Mar - 13 Mar
Tomorrow
13 Mar - 14 Mar
This weekend
13 Mar - 15 Mar
Next weekend
20 Mar - 22 Mar

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Our top choices for Mayo Clinic Florida hotels

Lobby lounge

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
1.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (469 reviews)
"Clean room, amazing staff great location "
United States
Darlene
The price is HK$1,275
HK$1,447 total
includes taxes & fees
20 Mar - 21 Mar
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Breakfast, lunch, dinner served; American cuisine

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
0.8 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (174 reviews)
"Great place to stay"
United States
Judy
The price is HK$1,354
HK$1,537 total
includes taxes & fees
4 Apr - 5 Apr
Hilton Jacksonville At Mayo Clinic
Terrace/patio

TownePlace Suites by Marriott Jacksonville East

TownePlace Suites by Marriott Jacksonville East
3.0 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (588 reviews)
"Comfortable room, very nice staff. Great location."
United States
Andrew
The price is HK$947
HK$1,075 total
includes taxes & fees
6 Apr - 7 Apr
TownePlace Suites by Marriott Jacksonville East
Lobby

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,001 reviews)
"Enjoyed the complimentary breakfast. "
United States
Andrew
The price is HK$860
HK$976 total
includes taxes & fees
5 Apr - 6 Apr
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
Lobby sitting area

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
2.6 km from Mayo Clinic Florida
8.8 out of 10, Excellent, (1,018 reviews)
"Staff was nice and room was clean "
United States
Charles
The price is HK$947
HK$1,075 total
includes taxes & fees
22 Mar - 23 Mar
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Terrace/patio

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
3.0 star property
0.4 km from Mayo Clinic Florida
8.4 out of 10, Very good, (766 reviews)
"Great location "
United States
Josiah Christine
The price is HK$1,260
HK$1,430 total
includes taxes & fees
21 Mar - 22 Mar
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
Free daily buffet breakfast

Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG
3.0 star property
4.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,000 reviews)
"Hotel was clean, breakfast was perfect."
United States
Kurt
The price is HK$1,025
HK$1,163 total
includes taxes & fees
25 Mar - 26 Mar
Holiday Inn Express Jacksonville Beach by IHG
Property amenity

Element Jacksonville Beach

Element Jacksonville Beach
3.0 star property
5.4 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (540 reviews)
"Great place (and location)!"
United States
Dale
The price is HK$1,260
HK$1,430 total
includes taxes & fees
5 Apr - 6 Apr
Element Jacksonville Beach
Exterior

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
4.2 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,042 reviews)
"Clean room, good breakfast and location"
United States
Jesus
The price is HK$1,020
HK$1,158 total
includes taxes & fees
22 Mar - 23 Mar
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
Lobby

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
5.9 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (3,773 reviews)
"Yes room was spotless and staff was amazing!"
United States
Martina
The price is HK$1,331
HK$1,511 total
includes taxes & fees
5 Apr - 6 Apr
Margaritaville Jacksonville Beach
Property amenity

TownePlace Suites by Marriott® Jacksonville Mayport

TownePlace Suites by Marriott® Jacksonville Mayport
3.0 star property
10.8 km from Mayo Clinic Florida
9.8 out of 10, Exceptional, (86 reviews)
"New, clean room and nice breakfast."
United States
Gregory
The price is HK$978
HK$1,110 total
includes taxes & fees
5 Apr - 6 Apr
TownePlace Suites by Marriott® Jacksonville Mayport
Down duvets, minibar, iron/ironing board, WiFi

The Hotel Palms

The Hotel Palms
3.5 star property
7.8 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (294 reviews)
"stayed here for an event and it was awesome"
United States
clayton
The price is HK$1,479
HK$1,679 total
includes taxes & fees
2 Apr - 3 Apr
The Hotel Palms
On the beach

Best Western Oceanfront

Best Western Oceanfront
3.0 star property
5.7 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,004 reviews)
"Great location, breakfast was delicious "
United States
Paul
The price is HK$1,127
HK$1,279 total
includes taxes & fees
22 Mar - 23 Mar
Best Western Oceanfront
Sports facility

Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
Southside, 8.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,000 reviews)
"very friendly staff!! i love staying here!!"
United States
Evani
The price is HK$892
HK$1,013 total
includes taxes & fees
5 Apr - 6 Apr
Hyatt Place Jacksonville / St. Johns Town Center
2 restaurants, breakfast served

The Lodge and Club at Ponte Vedra Beach

The Lodge and Club at Ponte Vedra Beach
5.0 star property
6.3 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (689 reviews)
"Clean room, excellent service and only steps from the ocean. The facility could use some TLC but, all in all, a wonderful place to stay. We’ll be back for sure. "
United States
Robert
The price is HK$3,905
HK$4,581 total
includes taxes & fees
12 Apr - 13 Apr
The Lodge and Club at Ponte Vedra Beach
Lounge

AC Hotel Jacksonville St Johns Town Center

AC Hotel Jacksonville St Johns Town Center
2.5 star property
Southside, 8.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (181 reviews)
"Staff was excellent...highly recommend this Hotel"
Canada
Robert
The price is HK$1,479
HK$1,679 total
includes taxes & fees
5 Apr - 6 Apr
AC Hotel Jacksonville St Johns Town Center
Exterior

Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Holiday Inn Express & Suites Jacksonville - Town Center by IHG
2.5 star property
Southside, 7.7 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (1,000 reviews)
"Great location, friendly staff, nice rooms, great breakfast."
United States
Michelle
The price is HK$955
HK$1,084 total
includes taxes & fees
2 Apr - 3 Apr
Holiday Inn Express & Suites Jacksonville - Town Center by IHG
Couples treatment room(s), sauna, hot tub, steam room, body treatments

Ponte Vedra Inn & Club

Ponte Vedra Inn & Club
5.0 star property
6.3 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (816 reviews)
"Amazing. Loved it "
United States
Carol
The price is HK$5,078
HK$5,888 total
includes taxes & fees
20 Mar - 21 Mar
Ponte Vedra Inn & Club
2 outdoor pools, open 7:00 AM to 9:00 PM, pool umbrellas, pool loungers

Hampton Inn Jacksonville Beach/Oceanfront

Hampton Inn Jacksonville Beach/Oceanfront
3.0 star property
6.3 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (2,638 reviews)
"Everyone was friendly, kind and went out of their way to help with anything we needed. Great staff, great stay!"
United States
Barbara
The price is HK$1,406
HK$1,596 total
includes taxes & fees
5 Apr - 6 Apr
Hampton Inn Jacksonville Beach/Oceanfront
Lobby

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
8.5 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,013 reviews)
"Very friendly staff, good restaurants in hotel and in the complex "
United States
Richard
The price is HK$1,238
HK$1,381 total
includes taxes & fees
5 Apr - 6 Apr
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mayo Clinic Florida Hotel Reviews

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

10/10 Excellent
"Excelent"
Kay 1-night trip
Posted 12 hours ago
Margaritaville Jacksonville Beach

Hotels near other Mayo Clinic Florida attractions

Windsor Parke Golf Club

Enjoy a round of golf in Jacksonville at Windsor Parke Golf Club. Amble around the area's beautiful beaches or attend a sporting event.
See properties

Windsor Commons Shopping Center

You can find the perfect gifts to bring home at Windsor Commons Shopping Center during your trip to Jacksonville. Experience the area's acclaimed theatre scene and great live music.
See properties

Frequently asked questions

What's the area like around Mayo Clinic Florida?
Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, take a look at the 48 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to Mayo Clinic Florida?
Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Other good choices close by include Hilton Jacksonville At Mayo Clinic and Residence Inn By Marriott Jacksonville - Mayo Clinic Area.
How many hotels are there near Mayo Clinic Florida?
Expedia has 48 hotels and other accommodation options within a mile from Mayo Clinic Florida.
If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view the top deals on offer near Mayo Clinic Florida.
What can I see and do near Mayo Clinic Florida?
You can catch a show at SeaWalk Pavillion, Players by the Sea and SeaWalk Pavillion. Spend some time exploring the the natural beauty of Huguenot Park, Oceanfront Park and Cradle Creek Preserve. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.

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