Florence Mcleod Regional Medical Center Hotels: 2026 Limited-Time Hotel Deals @Expedia

A modern building with a curved glass facade, surrounded by a well-maintained lawn and several trees.

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Our top choices for Mcleod Regional Medical Center hotels

A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.

A modern bar area with a long counter, multiple bar stools, and a variety of bottles and glasses.

A modern bar area with a long counter, bar stools, and a variety of bottles and glasses.

A modern lounge area with brick walls, large windows, and contemporary furniture.

1. Hyatt Place Florence Downtown

0.7 km from Mcleod Regional Medical Center

Shanti

HK$785

HK$879 total

includes taxes & fees

2 Nov - 3 Nov

A restaurant with brick walls, framed awards, and a bar area.

An outdoor patio area with a brick wall, a covered seating area with string lights, and potted plants.

A spacious living room with a wooden floor, a ceiling fan, and a dining area with a wooden table and chairs.

A spacious kitchen with a dining area, a living room with a fireplace, and a cozy seating arrangement.

2. Hotel Florence, Tapestry Collection by Hilton

0.8 km from Mcleod Regional Medical Center

Ankh

HK$901

HK$1,009 total

includes taxes & fees

1 Nov - 2 Nov

3. Rodeway Inn Florence Downtown

1.2 km from Mcleod Regional Medical Center

HK$334

HK$385 total

includes taxes & fees

8 Nov - 9 Nov

A modern kitchen with stainless steel appliances, a gray sofa, and a ceiling fan.

A modern living room with a brick wall, a grey sofa, a wooden coffee table, and a view through large windows.

A modern living room with a grey sofa, a round coffee table, a grey armchair with patterned cushions, a floor lamp, and a large TV mounted on the wall.

A modern kitchen with a built-in dishwasher, a large island with a sink, pendant lights, and a ceiling fan.

4. The Urban Flats

0.8 km from Mcleod Regional Medical Center

HK$2,244

HK$3,691 total

includes taxes & fees

20 Oct - 21 Oct

A spacious lobby with a checkered floor, a reception desk, and a chandelier.

A hotel room with two beds, a desk with a computer, a chair, and a bathroom with a mirror.

A vending area with snack and drink options, including Pepsi refrigerators and a 'MARKET' display with various products.

A two-story building with a brick facade, a flat roof, and a covered entrance area.

5. Howard Johnson by Wyndham Florence

5.5 km from Mcleod Regional Medical Center

HOMERO

HK$507

HK$568 total

includes taxes & fees

14 Oct - 15 Oct

A hotel lobby with a reception desk, seating area, and a television screen.

A Comfort Inn & Suites hotel with a covered entrance, brick facade, and multiple windows.

A hotel room with a bed, a sofa, an ottoman, and a lamp.

A hotel room with a sectional sofa, two ottomans, a bed with a green bedspread, and framed pictures on the wall.

6. Comfort Inn & Suites Florence Center Area

7 km from Mcleod Regional Medical Center

HK$794

HK$889 total

includes taxes & fees

1 Nov - 2 Nov

A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.

A hotel room with a large bed, a desk with a lamp, a chair, a TV, and a window with curtains.

A modern kitchen with a patterned backsplash, wooden cabinets, and stainless steel appliances.

A modern hotel with a 'Park Inn by Radisson' sign, featuring a covered entrance, multiple windows, and a parking lot.

7. Park Inn by Radisson Florence, SC

5.5 km from Mcleod Regional Medical Center

Windia

HK$701

HK$785 total

includes taxes & fees

18 Oct - 19 Oct

A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.

A lobby with leather sofas, a coffee table, potted plants, and a reception desk.

A corridor with shelves stocked with snacks and a frozen food display.

An indoor swimming pool with clear water, surrounded by a checkered wall pattern, and equipped with multiple seating areas and a lifeguard station.

8. Hampton Inn & Suites Florence-North-I-95

5.7 km from Mcleod Regional Medical Center

Ashokraju

HK$961

HK$1,076 total

includes taxes & fees

20 Oct - 21 Oct

A hotel room with two beds, a desk with a TV, and a bathroom visible through an open door.

A large, two-story building with a central entrance flanked by columns, labeled "DIR FRANK B. LEE NURSING BUILDING."

An outdoor patio area with brick walls, a fire pit, and outdoor seating.

A coffee station with two coffee machines, a coffee press, and various coffee-related items on a wooden counter.

9. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

9.1 km from Mcleod Regional Medical Center

Christopher

HK$957

HK$1,150 total

includes taxes & fees

13 Oct - 14 Oct

An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.

A snack kiosk with a variety of snacks and beverages, a sign for a 24/7 market, and a sign for local items.

A modern hotel with a prominent 'TRU by Hilton' sign, a well-lit entrance, and a landscaped front yard.

A modern lounge area with seating, tables, and a pool table.

10. Tru by Hilton Florence I-95

5.9 km from Mcleod Regional Medical Center

Tiffany

HK$794

HK$936 total

includes taxes & fees

2 Nov - 3 Nov

A hotel entrance with a stone facade, glass doors, and a number '501' above.

An indoor swimming pool with a tiled floor, a pool ladder, and lounge chairs.

A hotel reception area with a wooden floor, a reception desk, a seating area with chairs, and a decorative wall with a tree pattern.

A corner market with shelves stocked with snacks and beverages, and two large refrigerators.

11. Fairfield Inn & Suites by Marriott Florence I-20

6.9 km from Mcleod Regional Medical Center

HK$927

HK$1,038 total

includes taxes & fees

25 Oct - 26 Oct

A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.

A reception area with a wooden desk, a map on the wall, and a sign welcoming visitors to Florence, SC.

A modern kitchen with a coffee station, a dining area with a table and chairs, and a living area with a sofa and a coffee table.

A modern lounge area with a sofa, armchairs, and small tables.

12. TownePlace Suites by Marriott Florence

7 km from Mcleod Regional Medical Center

Crystal

HK$861

HK$964 total

includes taxes & fees

2 Nov - 3 Nov

A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.

A modern cafeteria with long wooden tables, green chairs, and yellow accents.

A hotel with a modern design, featuring a prominent sign for the 'Country Inn & Suites by Radisson.'

An outdoor patio with a wooden table and wicker chairs, a barbecue grill, and a swimming pool in the background.

13. Spark by Hilton Florence North I-95, SC

5.5 km from Mcleod Regional Medical Center

Tienia

HK$660

HK$771 total

includes taxes & fees

25 Oct - 26 Oct

A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.

A hotel room with a sofa, a dining table, a coffee maker, a TV, and artwork on the wall.

A hotel room with a bed, a desk, a TV, a refrigerator, and a painting on the wall.

A conference room with round tables, chairs, and a carpeted floor.

14. Staybridge Suites Florence - Civic Center by IHG

8.1 km from Mcleod Regional Medical Center

Tishia

HK$1,059

HK$1,187 total

includes taxes & fees

25 Oct - 26 Oct

A spacious lobby with a reception desk, seating area, and large windows.

An indoor swimming pool with clear poolside areas, a lifeguard station, and a view of the outside.

A Hilton Garden Inn with a large, multi-story building, a covered entrance, and a parking lot.

A spacious lobby with a large fireplace, comfortable seating, and potted plants.

15. Hilton Garden Inn Florence

7.2 km from Mcleod Regional Medical Center

Derrick

HK$927

HK$1,039 total

includes taxes & fees

18 Oct - 19 Oct

A spacious lobby with a high ceiling, a central seating area with armchairs and a coffee table, a flat-screen TV, and a dining area with tables and chairs.

A hotel with a modern design, featuring multiple floors and a parking lot.

A spacious lobby with a large seating area, a flat-screen TV, and a fireplace.

A modern hotel lobby with a fireplace, seating area, and a reception desk.

16. Residence Inn Marriott Florence

7.2 km from Mcleod Regional Medical Center

HK$873

HK$977 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with two beds, a wooden headboard, a window with curtains, and a wall-mounted air conditioner.

A spacious lobby with a reception desk, a large window display, and a 'market' sign on the wall.

A modern kitchen with a built-in coffee station, a refrigerator, and a seating area with a patterned rug.

17. SpringHill Suites by Marriott Florence

7.2 km from Mcleod Regional Medical Center

HK$727

HK$861 total

includes taxes & fees

18 Oct - 19 Oct

A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.

A hotel lobby with a reception desk, seating area, and a welcome mat.

A hotel room with two beds, a desk, a TV, and a window with patterned curtains.

A lobby with a fireplace, seating area, and a television.

18. Hampton Inn & Suites Florence Center

7.2 km from Mcleod Regional Medical Center

Ryan

HK$894

HK$1,001 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a large bed, a desk with a chair, a television, and a walk-in closet.

A reception area with a modern design, featuring a reception desk, a digital display, and a sign for Holiday Inn Express & Suites.

A hotel pool area with two pools, a lifeguard stand, and a towel service station.

A coffee station with two coffee machines and a display of coffee pods and cups.

19. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

8 km from Mcleod Regional Medical Center

HK$895

HK$1,002 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a desk, chair, bed, and a yellow sofa.

A hotel dining area with wooden tables and chairs, a fireplace, and a television.

A reception desk with a stone wall backdrop, a sign reading 'Quality Choice Hotels,' and a reception area with a wooden reception desk and two chairs.

A swimming pool with lounge chairs and a building with balconies.

20. Quality Inn & Suites Florence Civic Center

7.5 km from Mcleod Regional Medical Center

Sharhonda

HK$692

HK$775 total

includes taxes & fees

20 Oct - 21 Oct

View all properties

Top Mcleod Regional Medical Center Hotel Reviews

Park Inn by Radisson Florence, SC

8/10 Good

"Bath towel had a 2” hole in it. Should have been replaced"

La Quinta Inn & Suites by Wyndham Florence

10/10 Excellent

"Room was very clean and well presented. Bathroom was large and well stocked with extra tissue, towels, and shower had complementary shampoo, body wash and conditioner. Room had mini fridge and microwave. Large screen tv with all needed channels plus HBO. Breakfast buffet was excellent as well as all staff present. A very big bonus for us is the place is PET FRIENDLY!!! We will be back!"

Super 8 by Wyndham Florence

10/10 Excellent

"Room was clean. Bed was comfortable. This was a stop for the night, but we were happy with it, especially for the reasonable price."

Comfort Suites Florence I-95

10/10 Excellent

"Everything was excellent- the staff, the rooms, the parking, you name it. Very satisfied"

Spark by Hilton Florence North I-95, SC

10/10 Excellent

"Overview... it was Excellent. Clean, very comfortable spacious and convenient to restaurants. Staff was helpful and nice. Updates were very nice.Would definitely stay again."

Comfort Inn & Suites Florence Center Area

8/10 Good

"Nothing to say"

Pineapple House: Historic. Southern Charm. Walk Downtown.

10/10 Excellent

"Absolutely beautiful home in a quiet, safe neighborhood. It had everything I needed for an incredible stay. Excellent water pressure in shower. Comfortable bed, beautiful decor, snacks, water, and communication with owner was excellent. Easy check in and check out. Thank you for your hospitality and for being so welcoming during my stay. This is THE place to stay in Florence, SC. Thank you again. I will return in the future."

Come Stay A While

10/10 Excellent

"Loved the in unit washer and dryer. The house was visibly clean and smelled clean. Plenty of towels. The kitchen had cutting boards and pots and pans. Very comfortable and nice neighborhood. Host was very responsive."

Frequently asked questions

What's the area like around Mcleod Regional Medical Center?

Mcleod Regional Medical Center is located in a welcoming area of Florence known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 18 hotels and other accommodation options you'll find within a mile.

What's the best place to stay near Mcleod Regional Medical Center?

Hyatt Place Florence Downtown is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a restaurant. It's located just a short 0.4 mi (0.7 km) from Mcleod Regional Medical Center. Other good options within a short distance include Hotel Florence, Tapestry Collection by Hilton and The Urban Flats.

How many hotels can I expect to find near Mcleod Regional Medical Center?

Expedia has 18 hotels and other accommodation options within a mile from Mcleod Regional Medical Center.

If I need to cancel the hotel reservation for my stay near Mcleod Regional Medical Center, will I receive a refund?

Yes! You'll find that most hotel reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view top deals close to Mcleod Regional Medical Center.

What can I see and do near Mcleod Regional Medical Center?

You can enjoy live performances at FMU Performing Arts Center and Florence Little Theatre. You might spend a leisurely day outdoors at Florence Veterans Park and Greenwood Baseball Park and Playground. Create some family memories at Sky Zone Trampoline Park and Tilt Studio.

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Our top choices for Mcleod Regional Medical Center hotels

1. Hyatt Place Florence Downtown

2. Hotel Florence, Tapestry Collection by Hilton

3. Rodeway Inn Florence Downtown

4. The Urban Flats

5. Howard Johnson by Wyndham Florence

6. Comfort Inn & Suites Florence Center Area

7. Park Inn by Radisson Florence, SC

8. Hampton Inn & Suites Florence-North-I-95

9. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

10. Tru by Hilton Florence I-95

11. Fairfield Inn & Suites by Marriott Florence I-20

12. TownePlace Suites by Marriott Florence

13. Spark by Hilton Florence North I-95, SC

14. Staybridge Suites Florence - Civic Center by IHG

15. Hilton Garden Inn Florence

16. Residence Inn Marriott Florence

17. SpringHill Suites by Marriott Florence

18. Hampton Inn & Suites Florence Center

19. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

20. Quality Inn & Suites Florence Civic Center

Top Mcleod Regional Medical Center Hotel Reviews

Park Inn by Radisson Florence, SC

La Quinta Inn & Suites by Wyndham Florence

Super 8 by Wyndham Florence

Comfort Suites Florence I-95

Spark by Hilton Florence North I-95, SC

Comfort Inn & Suites Florence Center Area

Pineapple House: Historic. Southern Charm. Walk Downtown.

Come Stay A While

Frequently asked questions

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