Saint Charles Holiday Rentals

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Check prices for these dates

Tonight
27 Dec - 28 Dec
Tomorrow
28 Dec - 29 Dec
Next weekend
2 Jan - 4 Jan
In two weeks
9 Jan - 11 Jan

Our top choices for Saint Charles holiday rentals

Terrace/patio
Chic Des Moines 1BR with Amenities & Prime Location

Apartment in Downtown Des Moines

Chic Des Moines 1BR with Amenities & Prime Location
2.0 star property
10.0 out of 10, Exceptional, (1)
"Awesome !!"
United States
Heather
The price is HK$389
HK$1,090 total
includes taxes & fees
19 Jan - 20 Jan 2026
Chic Des Moines 1BR with Amenities & Prime Location
1 bedroom, free WiFi, bed sheets
Sleepover: Magnificent Studio & Gym - Des Moines

Apartment in Drake

Sleepover: Magnificent Studio & Gym - Des Moines
9.4 out of 10, Exceptional, (3)
"Stayed for my daughter’s graduation from Drake University. Location was perfect!"
United States
Gerda B.
The price is HK$537
HK$1,515 total
includes taxes & fees
27 Jan - 28 Jan 2026
Sleepover: Magnificent Studio & Gym - Des Moines
Fridge, microwave, oven, stovetop
Sleepover: Attractive Studio and Gym - Des Moines

Apartment in Drake

Sleepover: Attractive Studio and Gym - Des Moines
10.0 out of 10, Exceptional, (2)
"Clean and quiet for our stay. "
United States
Jackie
The price is HK$413
HK$1,377 total
includes taxes & fees
28 Dec - 29 Dec
Sleepover: Attractive Studio and Gym - Des Moines
Interior
Quiet Studio on Grand Ave - Heart of Downtown

Apartment in Downtown Des Moines

Quiet Studio on Grand Ave - Heart of Downtown
9.4 out of 10, Exceptional, (6)
"Property was in a good location, street parking was very easy. Host was incredibly responsive and helpful. "
United States
Cameron W.
The price is HK$376
HK$7,428 total
includes taxes & fees
28 Dec - 29 Dec
Quiet Studio on Grand Ave - Heart of Downtown
Microwave, oven, stovetop, dishwasher
Cozy Cottage Near Downtown Walkable to Dining and Boutique Shopping

Cottage in Woodland Heights

Cozy Cottage Near Downtown Walkable to Dining and Boutique Shopping
2.0 star property
10.0 out of 10, Exceptional, (2)
"Cozy, had everything we needed, convenient "
United States
Jordan S.
The price is HK$623
HK$1,734 total
includes taxes & fees
29 Dec - 30 Dec
Cozy Cottage Near Downtown Walkable to Dining and Boutique Shopping
Terrace/patio
Modern Comfort Meets Affordable Luxury – Your Perfect Stay Awaits!

Apartment in Downtown Des Moines

Modern Comfort Meets Affordable Luxury – Your Perfect Stay Awaits!
10.0 out of 10, Exceptional, (2)
"No issues, everything went very smoothly. Second tv in bedroom is nice if you like watching TV in bed"
United States
Kevin B.
The price is HK$505
HK$1,301 total
includes taxes & fees
19 Jan - 20 Jan 2026
Modern Comfort Meets Affordable Luxury – Your Perfect Stay Awaits!
Games room
Kasa Downtown Des Moines

Aparthotel in Downtown Des Moines

Kasa Downtown Des Moines
4.0 star property
9.2 out of 10, Wonderful, (111)
"Excellent stay! Very clean apartment and safe building."
United States
Bill
The price is HK$727
HK$1,337 total
includes taxes & fees
28 Dec - 29 Dec
Kasa Downtown Des Moines
Smart TV, fireplace
Sleepover: Charming 1BD/1BA - Downtown Des Moines

Apartment in Woodland Heights

Sleepover: Charming 1BD/1BA - Downtown Des Moines
10.0 out of 10, Exceptional, (1)
"Convenient to Sherman Hill and downtown. Quiet. "
United States
Abby H.
The price is HK$553
HK$1,533 total
includes taxes & fees
4 Jan - 5 Jan 2026
Sleepover: Charming 1BD/1BA - Downtown Des Moines
Smart TV
Modern Studio - walk to Wells Fargo Arena

Apartment in Downtown Des Moines

Modern Studio - walk to Wells Fargo Arena
9.0 out of 10, Wonderful, (8)
"The location was perfect for the Iowa Events Center. Good apartment, and very clean."
United States
Hugo M.
The price is HK$419
HK$7,523 total
includes taxes & fees
28 Dec - 29 Dec
Modern Studio - walk to Wells Fargo Arena
Terrace/patio
Cozy 1B1B w/Wi-Fi, Balcony Views, Coffee + Parking

Apartment in Downtown Des Moines

Cozy 1B1B w/Wi-Fi, Balcony Views, Coffee + Parking
10.0 out of 10, Exceptional, (25)
"This was a great place, clean, comfortable and location is amazing."
United States
Krystal D.
The price is HK$509
HK$1,353 total
includes taxes & fees
28 Dec - 29 Dec
Cozy 1B1B w/Wi-Fi, Balcony Views, Coffee + Parking
Outdoor dining
Spacious Studio Unit in Des Moines

Apartment in Downtown Des Moines

Spacious Studio Unit in Des Moines
9.0 out of 10, Wonderful, (2)
"We really enjoyed our stay at this cute little Studio in Des Moines. The location is great - right next to the Capital and Interstate. Will be back again soon :)"
United States
Amber V.
The price is HK$389
HK$1,047 total
includes taxes & fees
19 Jan - 20 Jan 2026
Spacious Studio Unit in Des Moines
Outdoor dining
The Luxe Black Haven (340)

Apartment in Downtown Des Moines

The Luxe Black Haven (340)
9.4 out of 10, Exceptional, (3)
"We enjoyed staying at "
United States
Diane V.
The price is HK$389
HK$1,089 total
includes taxes & fees
26 Jan - 27 Jan 2026
The Luxe Black Haven (340)
Outdoor dining
A lush, green-themed retreat home in Des Moines’ vibrant East Village.

Apartment in Downtown Des Moines

A lush, green-themed retreat home in Des Moines’ vibrant East Village.
9.4 out of 10, Exceptional, (10)
"Very comfortable place to stay. Easy to get around to all events. The only thing i would change is the thickness of mattress was a bit hard on my old back. Would definitely book again "
United States
Anonymous traveller
The price is HK$389
HK$1,090 total
includes taxes & fees
20 Jan - 21 Jan 2026
A lush, green-themed retreat home in Des Moines’ vibrant East Village.
Fridge, microwave, oven, stovetop
Boho Loft / Skyline View / Walk to Arena Events

Apartment in Downtown Des Moines

Boho Loft / Skyline View / Walk to Arena Events
10.0 out of 10, Exceptional, (6)
"Wonderful location! "
United States
Travis
The price is HK$633
HK$1,492 total
includes taxes & fees
20 Jan - 21 Jan 2026
Boho Loft / Skyline View / Walk to Arena Events
Outdoor dining
Skyline Serenity 2BR/2BA with Stunning City Views

Apartment in Downtown Des Moines

Skyline Serenity 2BR/2BA with Stunning City Views
2.0 star property
9.8 out of 10, Exceptional, (8)
"Was a great place to stay with my girlfriends for a concert at the Casey's center - very walkable & close to many bars and food places. Liked the games in community room in the basement! Would definitely stay again. "
United States
Angela
The price is HK$638
HK$1,497 total
includes taxes & fees
27 Jan - 28 Jan 2026
Skyline Serenity 2BR/2BA with Stunning City Views
Fridge, microwave, oven, stovetop
Good Vibes 2-Bedroom Apartment in Waukee - Central Location & Modern Comforts

Apartment in Waukee

Good Vibes 2-Bedroom Apartment in Waukee - Central Location & Modern Comforts
2.0 star property
10.0 out of 10, Exceptional, (8)
"The location was was close top everything that we needed. We were very impressed with the cleanliness of the condo!"
United States
Bill S.
The price is HK$735
HK$1,920 total
includes taxes & fees
29 Dec - 30 Dec
Good Vibes 2-Bedroom Apartment in Waukee - Central Location & Modern Comforts
Microwave, oven, stovetop, dishwasher
Welcome to Dog Moines- Skywalk connected pet-friendly studio. NO pet fees!

Apartment in Downtown Des Moines

Welcome to Dog Moines- Skywalk connected pet-friendly studio. NO pet fees!
2.0 star property
10.0 out of 10, Exceptional, (3)
"Great location, walkable area, pet friendly."
United States
Faby H.
The price is HK$731
HK$1,254 total
includes taxes & fees
27 Jan - 28 Jan 2026
Welcome to Dog Moines- Skywalk connected pet-friendly studio. NO pet fees!
Fridge, microwave, oven, stovetop
The Cozy Cottage - Entire house in Des Moines

Holiday Home in Greater South Side

The Cozy Cottage - Entire house in Des Moines
9.6 out of 10, Exceptional, (7)
"This place worked for us 3 adults well. The beds were comfy and a quiet neighborhood. Wed stay there again. "
United States
Shelley B.
The price is HK$715
HK$1,559 total
includes taxes & fees
1 Jan - 2 Jan 2026
The Cozy Cottage - Entire house in Des Moines
Interior
Spacious 2BR 2BA 3BD with Gorgeous Skyline View! Direct Skywalk Access too!

Condo in Downtown Des Moines

Spacious 2BR 2BA 3BD with Gorgeous Skyline View! Direct Skywalk Access too!
2.0 star property
9.4 out of 10, Exceptional, (3)
"We were in town for the Des Moines marathon, and the location was perfect- a block from start/finish. Clean, garage parking, and key-less access was a plus. Great communication throughout booking and stay."
United States
Carole H.
The price is HK$583
HK$2,003 total
includes taxes & fees
5 Jan - 6 Jan 2026
Spacious 2BR 2BA 3BD with Gorgeous Skyline View! Direct Skywalk Access too!
Fridge, microwave, oven, stovetop
The Hen House Country Living with Farm Life Appeal Indianola, IA

Holiday Home in Indianola

The Hen House Country Living with Farm Life Appeal Indianola, IA
10.0 out of 10, Exceptional, (8)
"Lori and Les make you feel right at home. They go above and beyond to ensure you have everything you could need and more. The farm is so peaceful and watching the animals is entertaining."
United States
Valerie
The price is HK$1,049
HK$1,469 total
includes taxes & fees
6 Jan - 7 Jan 2026
The Hen House Country Living with Farm Life Appeal Indianola, IA
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Saint Charles Hotel Reviews

Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

10/10 Excellent
"Great location and friendly check in"
Eric 1-night trip
Posted 4 days ago
Home2 Suites by Hilton Des Moines at Drake University

Find out more about Saint Charles

Search for holiday rentals in Saint Charles on Expedia! You can easily find your home rentals, villas, holiday apartments in Saint Charles using one of the methods below:

  • View our selection of featured holiday rentals in Saint Charles
  • Use the map to find apartments and other holiday homes in the Saint Charles neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Saint Charles while they last

Look no further and take a look at our great range of rental properties in Saint Charles!

Frequently asked questions

Can I find holiday rentals in Saint Charles?

Yes, there are holiday rentals close to the most popular sights in Saint Charles, or you can select a more secluded option if you're looking for a relaxing stay.

What are some of the best holiday rentals that Saint Charles has to offer?

LUXURY GETAWAY! ARCADE, POOL TBL, PING PONG, HOT TUB, DECK! ACCESS TO POOLS!: This holiday home rental outside of Saint Charles is located next to a golf course, and has a fireplace, a balcony and a BBQ to put you at ease in your new surroundings. It has 5 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. It offers a garden, a selection of games and 1 hot tub so that you can immerse yourself in your holiday.

What can I see and do in Saint Charles?

While exploring the area, visit family-friendly sights like Blank Park Zoo, or get outside and enjoy nature at Lake Ahquabi State Park. In the wider area, you’ll find Imes Bridge and John Wayne Birthplace Museum.

What are holiday rentals like in Saint Charles?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in Saint Charles. Holiday rentals provide amenities like WiFi and washers and dryers so you'll have a home away from home. If you're concerned about a sanitised environment, holiday rentals can provide a sense of privacy away from public hotel lifts and lobbies packed with people while still allowing you the experience of travel. You'll also get more space in a holiday rental than in a standard hotel, which is another reason why a holiday rental is an attractive option for a family trip.