Santa Cruz hotels from HK$297

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Tonight
9 Dec - 10 Dec
Tomorrow
10 Dec - 11 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

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Our top choices for Santa Cruz hotels

Seasonal outdoor pool
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (346)
"Wonderful staff with beautiful pool area and amenities. Great restaurant too."
Canada
Jay
The price is HK$1,020
HK$1,020 total
9 Jan - 10 Jan 2026
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Restaurant
Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra

3.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (73)
"Great Spot"
United States
Jose
The price is HK$297
HK$297 total
24 Dec - 25 Dec
Ibis Santa Cruz DE LA Sierra
Outdoor pool
Sun Hotel

Sun Hotel

3.5 star property
Santa Cruz
8.4 out of 10, Very good, (329)
"Staff spoke English. Airport pickup beat any US hotel. Rooms nice. Restaurant was ok"
United States
Peter
The price is HK$697
HK$697 total
14 Dec - 15 Dec
Sun Hotel
Lounge
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (253)
"Nice hotel "
United States
Narciso Lorenzo
The price is HK$498
HK$498 total
18 Dec - 19 Dec
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Indoor pool, outdoor pool, pool umbrellas
Camino Real Hotel

Camino Real Hotel

4.5 star property
Santa Cruz
8.8 out of 10, Excellent, (407)
"The parrots. Unique"
United States
Juan P
The price is HK$1,400
HK$1,400 total
25 Dec - 26 Dec
Camino Real Hotel
City view from property
HOTEL OSHO

HOTEL OSHO

3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (34)
"Hot tub worked well and room was very comfortable! 24 hr market across the street came in handy. The best hotel I've stayed at in Bolivia!"
United States
Robert
HOTEL OSHO
Reception
Hotel Cortez

Hotel Cortez

3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (122)
"The staff and property are second to none! "
United States
Cynthia
The price is HK$965
HK$965 total
9 Jan - 10 Jan 2026
Hotel Cortez
Outdoor pool, pool umbrellas, pool loungers
Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel

5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (211)
"Great hotel, food and location albeit a little expensive "
United States
Reinaldo
The price is HK$865
HK$865 total
19 Dec - 20 Dec
Marriott Santa Cruz de la Sierra Hotel
Front of property
Chairú Eco Hotel

Chairú Eco Hotel

3.5 star property
Santa Cruz
9.6 out of 10, Exceptional, (47)
"Nice property. Would definitely stay there again and again. Only negative was on our last night there was a really noisy party next door that lasted until 2am. "
United States
Andrew
Chairú Eco Hotel
Exterior
Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra

5.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (103)
"Great location and very clean hotel. Will stay again soon."
United States
William
The price is HK$778
HK$778 total
26 Dec - 27 Dec
Novotel Santa Cruz De La Sierra
Terrace/patio
Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz

3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (93)
"Come and go easily, intellectual and kind owners who are working hard to make the property improvements that will bring this hotel up to the next level. A family friendly environment with easy walking distance to everything you need. Bed was not the best, but I know they are upgrading so I appreciate the ongoing process. For a few nights stay, the deals are very fair prices. "
United States
Andrew
Apart Hotel Premium Suites Santa Cruz
Reception
Lido Hotel

Lido Hotel

3.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (30)
"Very helpful and nice staff. Quiet location. near the central plaza. Great value "
United Kingdom
David
The price is HK$355
HK$355 total
23 Dec - 24 Dec
Lido Hotel
Exterior
Delfines Collection Hotel By Mercure

Delfines Collection Hotel By Mercure

3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (71)
"Clean comfortable rooms "
United States
mary
The price is HK$316
HK$316 total
13 Dec - 14 Dec
Delfines Collection Hotel By Mercure
Outdoor pool, open 9:00 AM to 10:00 PM, free pool cabanas
TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz

4.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (145)
"Nice stay with good service "
United States
Jianyuan
The price is HK$770
HK$770 total
18 Dec - 19 Dec
TRYP by Wyndham Santa Cruz
Outdoor pool, open 9:00 AM to 8:00 PM, pool loungers
Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol

3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (81)
"Good price, great hotel!"
United States
James
The price is HK$303
HK$303 total
14 Dec - 15 Dec
Premium Suites Deluxe Aparthotel Equipetrol
Premium bedding, minibar, in-room safe, desk
Hotel LP Santa Cruz Centro

Hotel LP Santa Cruz Centro

3.0 star property
Santa Cruz
8.0 out of 10, Very good, (280)
"Clean, friendly staff"
United States
Giovanna
Hotel LP Santa Cruz Centro
Free WiFi
Hotel Las Américas

Hotel Las Américas

3.0 star property
Santa Cruz
6.0 out of 10, (1)
"O chuveiro foi impossível tomar um.banho de qualidade "
Brazil
Jean
The price is HK$299
HK$299 total
10 Dec - 11 Dec
Hotel Las Américas
Porch
Hotel Arenal

Hotel Arenal

3.5 star property
Santa Cruz
7.6 out of 10, Good, (59)
"Perfect hotel in a central location!"
United States
Max
The price is HK$493
HK$493 total
31 Dec - 1 Jan 2026
Hotel Arenal
Massages
Swissôtel Santa Cruz De La Sierra

Swissôtel Santa Cruz De La Sierra

4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (81)
"Beautiful hotel"
Australia
Joanna
The price is HK$1,152
HK$1,152 total
1 Jan - 2 Jan 2026
Swissôtel Santa Cruz De La Sierra
Front of property – evening/night
Hotel LP Equipetrol

Hotel LP Equipetrol

3.5 star property
Santa Cruz
8.2 out of 10, Very good, (201)
"Nice place to stay"
United States
Ricardo
Hotel LP Equipetrol
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Showing deals for:19 Dec - 21 Dec

Image gallery for HOTEL OSHO

City view from property

HOTEL OSHO

3.5 star property
Santa Cruz
9.2/10Wonderful (34 reviews)
16% off
Price is HK$363
HK$727 total
HOTEL OSHO
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Where to stay in Santa Cruz

Find the best Santa Cruz areas for the activities you enjoy most. Learn more about Santa Cruz
Learn more about Santa Cruz

Hamacas

When in Hamacas, you can plan a visit to Santa Cruz Zoo and Las Brisas Shopping Center, some noteworthy sights in the nearby area.

Stay near popular Santa Cruz attractions

Plaza 24 de Septiembre showing heritage elements and heritage architecture as well as a large group of people

Plaza 24 de Septiembre

4.4/5 (70 reviews)
Plaza 24 de Septiembre buzzes with local culture beneath swaying palms and colonial architecture. Climb the Cathedral's bell tower for spectacular city views while sampling authentic Bolivian coffee from vendors.
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San Lorenzo Cathedral which includes heritage elements, a church or cathedral and heritage architecture

San Lorenzo Cathedral

4.5/5 (36 reviews)
This grand neoclassical cathedral dominates Santa Cruz's skyline with its towering spires and ornate façade. Climb the bell tower at sunset for breathtaking panoramic views of the city.
See properties

Learn more about Santa Cruz

Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

See all hotels in Santa Cruz
San Lorenzo Cathedral which includes a park

Top Santa Cruz Hotel Reviews

Camino Real Hotel

Camino Real Hotel

10/10 Excellent
"Excellent hotel, I willl always used it in this location "
JHENNY 1-night trip
Posted 8 days ago
Camino Real Hotel

More cheap stays in Santa Cruz

Amaca Hostal

Amaca Hostal

249 Independencia Santa Cruz Departamento de Santa Cruz
Get rates

Frequently asked questions

What's the best place for a stay in Santa Cruz?
Ibis Santa Cruz DE LA Sierra is a favourite with Expedia customers. This hotel offers a restaurant and free parking. Reviews from our site also recommend Chairú Eco Hotel and Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel as top options for your trip. See all available top hotels, or vacation rentals in Santa Cruz.
What are some of the best holiday rentals that Santa Cruz has to offer?
Casa Vida: This highly rated holiday home rental in Santa Cruz is located in a rural location, and has an outdoor pool, a patio and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a full-sized fridge, a stovetop and a microwave, so that you can cook with friends or family. Kick off your shoes and enjoy yourself with a private garden and a selection of games. Some other homes for rent in Santa Cruz include Cozy and independent. Downtown house JH. and Jose Luis Noya. See all vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
What's the best budget-friendly accommodation in Santa Cruz?
Based on our traveller reviews, residencial francia - Hostel is a top choice for a less expensive stay. Other choices for your budget-friendly stay include Residencial Ikandire II and Nomad Hostel. View all budget hotels in Santa Cruz.
What's the best family accommodation in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a hotel with an outdoor pool and a restaurant, and it's a top choice on Expedia for families. Other choices for your child-friendly holiday include Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Novotel Santa Cruz De La Sierra. Also, attractions such as Santa Cruz Zoo and Play Land Amusement Park are fun for children of all ages. Find more child-friendly accommodations in Santa Cruz.
What's the best LGBTQ-friendly accommodation in Santa Cruz?
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. Swissôtel Santa Cruz De La Sierra and Radisson Hotel Santa Cruz are other good choices for your holiday. See all available hotels listed as LGBTQ-friendly in Santa Cruz.
What's the best dog-friendly accommodation option in Santa Cruz?
Ibis Santa Cruz DE LA Sierra is a top hotel for people travelling with their pets, and offers a restaurant and free WiFi for its human guests. Two other good options for you and your pet's trip include HOTEL OSHO and Hotel LP Equipetrol. See more pet-friendly hotel accommodations in Santa Cruz.
What's the best luxury accommodation option in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a luxury hotel with a full-service spa and a rooftop terrace, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Novotel Santa Cruz De La Sierra and Camino Real Hotel are other upscale choices for your holiday. Find more luxury hotels in Santa Cruz.
What are some accommodation options with pools in Santa Cruz?
Sun Hotel is a top hotel with a children's pool, an outdoor pool and free buffet breakfast. A couple of other options that feature an on-site pool include Yotau All Suites Hotel and Buganvillas Hotel Suites & Spa. View all hotels with pools in Santa Cruz.
What is the best spa hotel in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a top luxury spa hotel featuring a rooftop terrace, a fitness centre, tennis courts and a bar. Spend an afternoon at Hotel Spa where you'll find massage treatments. Other popular spa hotels in Santa Cruz include Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Hotel Cortez. See all spa hotels in Santa Cruz.
What's it like to stay in Santa Cruz?
Visitors to Santa Cruz will definitely enjoy the shopping. Tourists can also enjoy the city's cafés, zoo and cathedral. In Santa Cruz, there are 285 hotels and other accommodation options to choose from. Find out more about Santa Cruz.
What is there to see in Santa Cruz?
Cultural venues include Ethno-folkloric Museum, Cine Center and Sacred Art Museum. Landmarks like San Lorenzo Cathedral, Plaza 24 de Septiembre and Blacutt Square might be worth a visit. Natural beauty is on display at Guembe Biocenter, Lomas de Arena Regional Park and Arenal Park. Take a look at what more there is to see and do in Expedia's Santa Cruz guide.
How should I get around Santa Cruz?
If you want to venture outside the area, hop on a train at Santa Cruz de la Sierra Station. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.
What's the weather like in Santa Cruz?
The hottest months are usually October and November, with an average temperature of 26°C, while the coldest months are June and July, with an average of 21°C. Average annual precipitation for Santa Cruz is 1208 mm.

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