Jeffersonville 4 Stars Hotels

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Jeffersonville 4 Star Hotels

Tonight
29 Dec - 30 Dec
Tomorrow
30 Dec - 31 Dec
This weekend
2 Jan - 4 Jan
Next weekend
9 Jan - 11 Jan

Our top choices for Jeffersonville 4-star hotels

4 restaurants, breakfast, lunch, dinner served; American cuisine
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (3916)
"Great place to stay! "
United States
Rochelle
The price is HK$1,036
HK$1,219 total
includes taxes & fees
5 Jan - 6 Jan 2026
Galt House Hotel Trademark Collection by Wyndham
Sauna, body treatments, aromatherapy, hot stone massages
Omni Louisville Hotel

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1747)
"This is a beautiful hotel in a great location. Very kind staff and helpful with directions."
United States
Bonnie
The price is HK$1,299
HK$1,529 total
includes taxes & fees
1 Jan - 2 Jan 2026
Omni Louisville Hotel
Dinner served
Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1130)
"Staff was courteous, hotel was beautiful and clean, and breakfast was amazing!"
United States
Shunskis
The price is HK$950
HK$1,117 total
includes taxes & fees
11 Jan - 12 Jan 2026
Embassy Suites Louisville Downtown
Premium bedding, in-room safe, desk, laptop workspace
Derby City Gaming & Hotel - A Churchill Downs Property

Derby City Gaming & Hotel - A Churchill Downs Property

Derby City Gaming & Hotel - A Churchill Downs Property
4.0 star property
Louisville
9.4 out of 10, Exceptional, (1726)
"Great place to stay"
United States
april
Derby City Gaming & Hotel - A Churchill Downs Property
Lobby
The Brown Hotel

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1164)
"Fantastic place to stay in Louisville."
United States
Nathaniel
The Brown Hotel
Hypo-allergenic bedding, in-room safe, desk, laptop workspace
Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1021)
"Great location and accommodations."
United States
Steve
The price is HK$987
HK$1,161 total
includes taxes & fees
5 Jan - 6 Jan 2026
Hotel Genevieve part of JdV by Hyatt
Front of property
21c Museum Hotel Louisville

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1003)
"Staff was very kind, the art was fantastic, location was perfect to explore Whiskey Row, and we had a gorgeous room. Loved our time away there!"
United States
Tammy
The price is HK$897
HK$1,094 total
includes taxes & fees
2 Jan - 3 Jan 2026
21c Museum Hotel Louisville
Breakfast, lunch and dinner served
Hyatt Regency Louisville

Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
Downtown Louisville
8.8 out of 10, Excellent, (1002)
"Enjoyed our stay "
United States
Jedediah
The price is HK$987
HK$1,161 total
includes taxes & fees
8 Jan - 9 Jan 2026
Hyatt Regency Louisville
Exterior
Marriott Louisville East

Marriott Louisville East

Marriott Louisville East
4.0 star property
Jeffersontown
9.0 out of 10, Wonderful, (1003)
"Great stay"
United States
Brad
The price is HK$852
HK$1,003 total
includes taxes & fees
3 Jan - 4 Jan 2026
Marriott Louisville East
View from room
The Grady

The Grady

The Grady
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1011)
"Such an amazing hotel...restaurant is delicious! "
United States
Craig
The price is HK$1,126
HK$1,325 total
includes taxes & fees
5 Jan - 6 Jan 2026
The Grady
Restaurant
Louisville Marriott Downtown

Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1000)
"Very nice hotel. Great stay!"
United States
Brad
The price is HK$1,303
HK$1,533 total
includes taxes & fees
25 Jan - 26 Jan 2026
Louisville Marriott Downtown
Exterior
Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville
9.6 out of 10, Exceptional, (429)
"Great location. Great restraunt, great staff. Pleasurable experience!"
United States
Harrison
The price is HK$1,361
HK$1,602 total
includes taxes & fees
18 Jan - 19 Jan 2026
Hotel Distil, Autograph Collection
Exterior
Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (58)
"Amazing property! Best hotel in Louisville! Will be staying there again!"
United States
Norman
The price is HK$1,308
HK$1,539 total
includes taxes & fees
8 Jan - 9 Jan 2026
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Lobby
Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
Downtown Louisville
8.6 out of 10, Excellent, (1003)
"Excellent location and a great lobby bar with a top notch bourbon selection. "
United States
vincent
The price is HK$1,137
HK$1,338 total
includes taxes & fees
2 Jan - 3 Jan 2026
Seelbach Hilton Louisville Downtown
Premium bedding, down duvets, memory-foam beds, individually furnished
Stellar Suites

Stellar Suites

Stellar Suites
4.5 star property
Downtown Louisville
9.6 out of 10, Exceptional, (117)
"Clean and great location "
United States
Greg
The price is HK$825
HK$1,364 total
includes taxes & fees
14 Jan - 15 Jan 2026
Stellar Suites
Balcony
The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B
4.0 star property
New Albany
9.8 out of 10, Exceptional, (650)
"Awesome place to stay! "
United States
Richard
The price is HK$690
HK$780 total
includes taxes & fees
31 Dec - 1 Jan 2026
The Pepin Mansion Historic B&B
Seasonal outdoor pool
CozySuites at Nulu

CozySuites at Nulu

CozySuites at Nulu
4.0 star property
Downtown Louisville
8.2 out of 10, Very good, (26)
"The unit was clean, all communications were timely, the property has all the amenities, and NULU is very walkable. A perfect stay! My only regret is that I wasn't able to extend the stay. Highly recommended if you're in the Louisville area "
United States
William
The price is HK$554
HK$1,545 total
includes taxes & fees
28 Jan - 29 Jan 2026
CozySuites at Nulu
BBQ/picnic Area
stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville
4.0 star property
Clarksville
9.8 out of 10, Exceptional, (43)
"Excellent stay. One of my favorite hotels in the area. They never disappoint "
United States
Julia
The price is HK$1,146
HK$1,296 total
includes taxes & fees
2 Jan - 3 Jan 2026
stayAPT Suites Louisville North-Clarksville
Full-sized fridge, microwave, oven, stovetop
The Reserve on Main

The Reserve on Main

The Reserve on Main
4.0 star property
Downtown Louisville
10.0 out of 10, Exceptional, (1)
"Incredible stay. This stay was clean and inspiring for anyone wishing to take a break and recharge. We highly recommend this stay to everyone staying in the city. "
Canada
georgios
The price is HK$1,282
HK$1,877 total
includes taxes & fees
7 Jan - 8 Jan 2026
The Reserve on Main
Interior
Inn at St James Court

Inn at St James Court

Inn at St James Court
4.0 star property
Old Louisville
9.8 out of 10, Exceptional, (131)
"Lovely Victorian house in a gorgeous and convenient gorgeous neighborhood. "
United States
marcia
Inn at St James Court
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Jeffersonville.
Louisville Bourbon Inn

Louisville Bourbon Inn

1332 S 4th St Louisville KY
The price is HK$2,060 per night from 7 Jan to 8 Jan
HK$2,060
HK$2,391 total
7 Jan - 8 Jan 2026
includes taxes & fees
10/10 Exceptional! (20 reviews)
Still don't see what you're looking for?
See all properties in Jeffersonville.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Jeffersonville

Stroll along the Ohio River on the revitalised RiverStage, where summer concerts happen with Louisville's skyline as backdrop. History buffs can explore the Howard Steamboat Museum, then grab a bite at one of the charming restaurants in the walkable city centre.

See all hotels in Jeffersonville
Louisville, Kentucky; Shutterstock ID 361332

Top Jeffersonville Hotel Reviews

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

10/10 Excellent
"No breakfast, rooms was very clean"
Terry 1-night trip
Posted 3 days ago
Galt House Hotel Trademark Collection by Wyndham

Frequently asked questions

What are the best 4-star hotels in Jeffersonville?
If you're seeking deluxe comfort and loads of amenities during your Jeffersonville getaway, check out Galt House Hotel Trademark Collection by Wyndham. This 4-star hotel comes with a swimming pool and beauty services. 21c Museum Hotel Louisville also gets excellent reviews from Expedia travellers. Spa facilities and treatment rooms are among its conveniences.
How much does it cost to stay in a 4-star hotel in Jeffersonville?
To find a 4-star hotel in Jeffersonville that's within your budget, take advantage of Expedia's handy filter tool. Check out the available options during your chosen dates and use our pricing filter to set your limit. You can also list your results by the most budget-friendly escape first.

  • Search for the lowest price from HK$2,391

What's the difference between 5-star and 4-star hotels in Jeffersonville?
If you choose to stay at a 4-star hotel in Jeffersonville, you'll usually find loads of conveniences to keep you comfortable, such as a gym, restaurant and pool. You can look forward to top-quality service and upmarket accommodation. Pick a 5-star hotel and you'll have access to a few extra perks — think around-the-clock concierge, on-site spas and indulgent turndown services. You'll most likely get extra amenities and premium services at a 5-star retreat, but both are terrific options for luxury travellers.

Explore a world of travel with Expedia