A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

Panama City 5 Stars Hotels

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Check availability on Panama City 5 Star Hotels

Tonight
11 Oct - 12 Oct
Tomorrow
12 Oct - 13 Oct
Next weekend
16 Oct - 18 Oct
In two weeks
23 Oct - 25 Oct

Our top choices for Panama City 5-star hotels

A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.
A modern living room with a sofa set, a coffee table, and a dining area with chairs and a table.
A modern hotel room with a dining area, a TV, and a city view.
A hotel room with a bed, a TV, a desk, and a view of the cityscape through a window.

1. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
Bella Vista
United States
Avanel
HK$1,035
HK$1,139 total
includes taxes & fees
21 Oct - 22 Oct
Hotel Riu Plaza Panama
A person seated at a bar with a drink, in a room with a teal accent wall and hanging lights.
A modern interior with a decorative ceiling, a person in a white dress, and a blue-lit wall.
A modern building with a rooftop lounge area, large windows, and a balcony overlooking a cityscape.
A tall, modern building with a prominent logo at the top, surrounded by other high-rise buildings in a cityscape.

2. Waldorf Astoria Panama

Waldorf Astoria Panama
Bella Vista
United States
Aysha
HK$2,061
HK$2,267 total
includes taxes & fees
31 Oct - 1 Nov
Waldorf Astoria Panama
A balcony with a table, chairs, and a view of a city skyline across a body of water.
A spacious lobby with a round coffee table, seating areas, and a large wall clock.
A spacious lobby with high ceilings, modern furniture, and decorative lighting fixtures.
A hotel with a rooftop pool, lounge chairs, and a view of the sea.

3. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
Casco Viejo
United States
Jose
HK$2,755
HK$3,030 total
includes taxes & fees
3 Nov - 4 Nov
Sofitel Legend Casco Viejo, Panama City
A modern hotel room with a sofa, a coffee table, a TV mounted on the wall, and a dining area with a table and chairs.
A modern lobby with a staircase, marble flooring, and large windows with tropical plants.
A modern hotel entrance with a prominent 'Renaissance Hotel' sign, a well-lit outdoor area with a wooden structure, and a staircase leading to the upper floors.
An indoor swimming pool with lounge chairs and red chairs, surrounded by lush greenery and a modern interior design.

4. Renaissance Panama City Hotel

Renaissance Panama City Hotel
Bella Vista
United States
Carlos
HK$1,059
HK$1,165 total
includes taxes & fees
31 Oct - 1 Nov
Renaissance Panama City Hotel
A poolside area with lounge chairs and a view of the ocean.
A modern building with a symmetrical facade, multiple balconies, and a central atrium with lighting.
A modern bathroom with a large bathtub, two sinks, and a glass-enclosed shower area with a city view.
A modern hotel room with a large bed, a chair, a nightstand with a lamp, and a view of the cityscape at dusk.

5. JW Marriott Panama

JW Marriott Panama
San Francisco
United States
Detra Dorsey
HK$2,191
HK$2,410 total
includes taxes & fees
7 Nov - 8 Nov
JW Marriott Panama
A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.
A spacious hotel lobby with modern furniture, large windows, and a city view.
A spacious lobby with a curved ceiling, a central staircase, and a reception desk.
A modern building with a sign reading 'HYATT REGENCY.'

6. Hyatt Regency Panama City

Hyatt Regency Panama City
Bella Vista
United States
Mariah
HK$1,468
HK$1,614 total
includes taxes & fees
18 Oct - 19 Oct
Hyatt Regency Panama City
A hotel entrance with a central water feature, seating areas, and potted plants.
The entrance of The Santa Maria with a covered walkway and a view of the interior.
An outdoor dining area with wicker chairs and tables, a bar with bottles, and a pool in the background.
A pool with a central water feature, surrounded by seating areas and potted plants.

7. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Juan Diaz
United States
Carmen
HK$2,172
HK$2,389 total
includes taxes & fees
1 Nov - 2 Nov
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
A modern restaurant with large windows offering a city view, warm lighting, and contemporary furniture.
A high-rise building with a rooftop pool area, surrounded by other buildings.
A modern high-rise building with a prominent 'W' logo, surrounded by other buildings and a busy street at night.
A modern living room with a city view, featuring a purple accent wall, a white sofa, and a glass table.

8. W Panama

W Panama
Bella Vista
United States
Naomi
HK$1,814
HK$1,996 total
includes taxes & fees
1 Nov - 2 Nov
W Panama
A modern hotel pool area with lounge chairs and a clear view of the ocean.
A modern bar area with seating and a view of the city.
A modern interior with a spiral staircase, a large window, and a seating area.
A spacious lobby with a large seating area, a glass display case with bottles, and a view of the city at night.

9. Hilton Panama

Hilton Panama
Bella Vista
United States
Simon
HK$1,928
HK$2,121 total
includes taxes & fees
6 Nov - 7 Nov
Hilton Panama
A hotel with a pool, beach, and palm trees.
A beachfront hotel with a large building, a beach, and a clear sky.
A spacious lobby with a large seating area, a reception desk, and large windows offering a view of the ocean and palm trees.
A spacious lobby with a modern design, featuring a central seating area with sofas and ottomans, surrounded by large, open spaces and natural light.

10. The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
Veracruz
United States
Anna
HK$1,617
HK$1,779 total
includes taxes & fees
25 Oct - 26 Oct
The Westin Playa Bonita Panama
A modern living room with a sofa, round black ottomans, and a vase of flowers. A cityscape is visible through the window.
A rooftop swimming pool with a cityscape view, glass railings, and a modern architectural design.
A bar area with a long counter, multiple bar stools, and a television screen. There are large windows providing natural light and a view of the outdoors.
A cozy outdoor seating area with a wooden bench and white tables, surrounded by lush greenery and potted plants.

11. Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
Bella Vista
United States
Juliet
HK$1,954
HK$2,149 total
includes taxes & fees
17 Oct - 18 Oct
Bristol Panama, a Registry Collection Hotel
Lobby
Banquet hall
Breakfast area
Outdoor pool

12. Waymore Hotel Spa and Casino

Waymore Hotel Spa and Casino
Bella Vista
United States
Aldo
HK$798
HK$881 total
includes taxes & fees
2 Nov - 3 Nov
Waymore Hotel Spa and Casino
Terrace/patio
Room
Outdoor pool
Outdoor spa tub

13. Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
United States
MARVIN
HK$2,048
HK$2,262 total
includes taxes & fees
4 Nov - 5 Nov
Megapolis Hotel Panamá
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Panama City.
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz Tocumen Panama
HK$1,052
HK$1,209 total
10 Nov - 11 Nov
includes taxes & fees
Crowne Plaza Panama Airport by IHG
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Plaza de la Independencia Casco Viejo Panama City Panama
HK$1,594
HK$1,754 total
9 Nov - 10 Nov
includes taxes & fees
9/10 Wonderful! (1,013 reviews)
Central Hotel Panama Casco Viejo
Megapolis Hotel Panamá

Megapolis Hotel Panamá

Avenida Balboa Panama City
HK$1,282
HK$1,411 total
31 Oct - 1 Nov
includes taxes & fees
8.6/10 Excellent! (1,778 reviews)
Megapolis Hotel Panamá
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Panama City

The gleaming skyscrapers of this cosmopolitan capital stand in striking contrast to the colonial charm of Casco Viejo. Watch massive ships navigate the Canal locks, then sample ceviche at the seafood market where local fishermen bring their daily catch.

See all hotels in Panama City
A city skyline with high-rise buildings, a calm waterfront, and a sunset sky.

Top Panama City Hotel Reviews

Hyatt Regency Panama City

Hyatt Regency Panama City

10/10 Excellent
"Exactly what you would expect from hyatt resort"
Nehemiah 3-night trip
Posted 2 hours ago
Hyatt Regency Panama City
JW Marriott Panama

JW Marriott Panama

10/10 Excellent
"N/A"
Rhonda 3-night trip
Posted 3 hours ago
JW Marriott Panama

Frequently asked questions

What are the best 5-star hotels in Panama City?
According to Expedia guest reviews, Bristol Panama, a Registry Collection Hotel, W Panama and Waldorf Astoria Panama are among the top 5-star hotels in Panama City. Providing top-quality amenities and unmatchable service, you'll enjoy a luxurious and memorable stay.
How much does it cost to stay in a 5-star hotel in Panama City?
How much you pay for a 5-star hotel in Panama City can vary according to when you prefer to travel and how long you plan to stay, among other factors. Take advantage of our price per night filter and other search tools to find the best deal on a luxurious getaway.
  • Search for the lowest price per night from HK$1,209
What makes a hotel 5 stars in Panama City?
From fine dining restaurants and 24-hour gyms to swimming pools and the finest bedding, the 5-star experience in Panama City is all about comfort and luxury. But it takes more than just top-notch amenities to receive a 5-star rating. Hotels also have to offer remarkable guest-centric services like in-room beauty treatments, on-site laundry and dry cleaning and room service any time day or night.

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