Best De Soto Hotels in 2026 from HK$426 - Fully Refundable Options

Q: What are some of the best holiday rentals that De Soto has to offer?

Gated 35-Acre De Soto Estate: Pool, Lake & Patio! : This highly rated holiday home rental in De Soto offers a patio, a garden and a BBQ to help you feel perfectly comfortable in your new surroundings. It has 5 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. You and your friends and family can relax into your holiday with amenities such as a selection of games. See all vacation rentals in De Soto .

Q: What are some accommodation options with pools in De Soto?

Pear Tree Inn St. Louis Arnold : Features buffet, an outdoor pool and free self parking. Baymont Inn and Suites by Wyndham Farmington, MO and Drury Inn & Suites St. Louis Arnold are a couple of other choices that offer an on-site pool. View all hotels with pools in De Soto .

Q: What should I see while I'm in De Soto?

Natural beauty is on display at Sunrise Lake Beach , Big River and Big Lake . A couple of additional sights to add to your itinerary are Washington State Park and Redfield's Flea Market . Take a look at what more there is to see and do in Expedia's De Soto guide .

Q: Where is the best place to stay in De Soto?

Pear Tree Inn St. Louis Arnold , located 23.1 mi (37.2 km) from the heart of De Soto, is a top choice for your stay, based on our traveller data. Other good options for your trip to the area are Baymont Inn and Suites by Wyndham Farmington, MO and Comfort Inn Festus - St Louis South . See all available top hotels , or vacation rentals in De Soto .

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Our top choices for De Soto hotels

A modern hotel with a stone facade, multiple windows, outdoor seating, and a visible sign for the Holiday Inn Express & Suites.

1. Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Festus

Megnauth

HK$897 total

includes taxes & fees

22 Nov - 23 Nov

A hotel room with a bed, bedside tables, a desk, a chair, a lamp, and a window.

2. Hampton Inn & Suites By Hilton Festus

Festus

Misty

HK$1,000 total

includes taxes & fees

15 Nov - 16 Nov

A modern lobby with seating areas, a patterned carpet, and a cityscape mural on the wall.

3. La Quinta Inn & Suites by Wyndham Festus - St. Louis South

Festus

Vincent

HK$754 total

includes taxes & fees

8 Nov - 9 Nov

A hotel lobby with a reception desk, two red armchairs, a floral centerpiece, a framed cityscape picture, and a dining area in the background.

4. Comfort Inn Festus - St Louis South

Festus

Michelle

HK$638 total

includes taxes & fees

30 Nov - 1 Dec

A building with a covered entrance, columns, and a view of the sky.

5. Baymont by Wyndham Festus

Festus

Gretchen

HK$621 total

includes taxes & fees

30 Nov - 1 Dec

A lobby with a reception desk, blue sofas, a coffee table, and a plant display.

6. Drury Inn & Suites St. Louis Arnold

Arnold

Kristine

HK$1,143 total

includes taxes & fees

10 Nov - 11 Nov

A modern interior with a high ceiling, large windows, and a brick wall. There are orange chairs and a green sofa with orange cushions.

7. Pear Tree Inn St. Louis Arnold

Arnold

Lynda

HK$815 total

includes taxes & fees

20 Nov - 21 Nov

An indoor swimming pool with clear water, surrounded by lounge chairs and a tiled floor.

8. Hampton Inn Farmington

Farmington

Charlie

HK$930 total

includes taxes & fees

4 Dec - 5 Dec

9. Super 8 by Wyndham Pevely

Pevely

Steve

HK$559 total

includes taxes & fees

7 Dec - 8 Dec

An indoor swimming pool with a brick border, wooden walls, and a view of the outdoors.

10. Crown Pointe Lodge, BW Signature Collection

Farmington

christopher

HK$907 total

includes taxes & fees

20 Nov - 21 Nov

A reception area with a modern design, featuring a decorative wall piece, a small table with a bowl, and a patterned partition.

11. Holiday Inn Express & Suites Farmington by IHG

Farmington

January

HK$1,033 total

includes taxes & fees

22 Nov - 23 Nov

A spacious dining area with multiple tables and chairs, a coffee station, and a counter with various food items.

12. Days Inn & Suites By Wyndham Festus

Festus

Larry

HK$653 total

includes taxes & fees

26 Nov - 27 Nov

A cabin surrounded by a natural forest setting with a fire pit and outdoor seating.

13. Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

French Village

Jose

HK$1,141 total

includes taxes & fees

7 Dec - 8 Dec

A modern hotel room with a large bed, a desk with a lamp, a TV, and a wardrobe.

14. Motel 6 Bonne Terre, MO

Bonne Terre

Kathleen

HK$568 total

includes taxes & fees

20 Nov - 21 Nov

A dining area with tables and chairs, a kitchen area, and a TV mounted on the wall.

15. Baymont Inn and Suites by Wyndham Farmington, MO

Farmington

Kim

HK$488 total

includes taxes & fees

12 Nov - 13 Nov

A stone building with a white porch and a small garden with yellow flowers.

16. Corner George Inn Bed & Breakfast

Maeystown

Mark

HK$1,119 total

includes taxes & fees

8 Nov - 9 Nov

A hotel room with a large bed, two bedside tables, a nightstand, and a framed picture on the wall.

17. Quality Inn Farmington

Farmington

Tracy

HK$567 total

includes taxes & fees

12 Nov - 13 Nov

A hallway with a reception desk, framed artwork on the walls, and a QR code on the floor.

18. WoodSpring Suites St. Louis Arnold

Arnold

Mark

HK$770 total

includes taxes & fees

12 Nov - 13 Nov

A living room with a sofa, coffee table, and a small table with a vase. There is a window with blinds and a door in the background.

19. Super 8 by Wyndham Bonne Terre

Bonne Terre

Elizabeth

HK$525 total

includes taxes & fees

24 Nov - 25 Nov

A large, two-story house with a wrap-around porch and a central tower.

20. The Conner House B&B

Prairie du Rocher

James

HK$1,359 total

includes taxes & fees

9 Nov - 10 Nov

View all properties

Stay near popular De Soto attractions

Eastside Community Park

This area park offers a playground, basketball court, and shaded pavilion for family gatherings. Enjoy a picnic under mature trees or shoot hoops while children explore the age-appropriate play equipment.

See properties

Learn more about De Soto

Get away to De Soto! Enjoy the local cuisine and more.

See all hotels in De Soto

A rocky landscape with large boulders and a forested hill in the background.

Frequently Asked Questions

What are some of the best holiday rentals that De Soto has to offer?

Gated 35-Acre De Soto Estate: Pool, Lake & Patio!: This highly rated holiday home rental in De Soto offers a patio, a garden and a BBQ to help you feel perfectly comfortable in your new surroundings. It has 5 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. You and your friends and family can relax into your holiday with amenities such as a selection of games. See all vacation rentals in De Soto.

If I need to cancel my hotel reservation in De Soto, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in De Soto.

What's the best dog-friendly accommodation option in De Soto?

Cabin Springs. Escape to the quiet country. Fish, hike, kayak, see the stars. is a top dog-friendly option for your stay. See more pet-friendly hotel accommodations in De Soto.

What are some accommodation options with pools in De Soto?

Pear Tree Inn St. Louis Arnold: Features buffet, an outdoor pool and free self parking. Baymont Inn and Suites by Wyndham Farmington, MO and Drury Inn & Suites St. Louis Arnold are a couple of other choices that offer an on-site pool. View all hotels with pools in De Soto.

What is staying in De Soto like?

Visitors can enjoy all that De Soto has to offer, including its restaurants. In De Soto, there are 5 hotels and other accommodation options to choose from. Find out more about De Soto.

What should I see while I'm in De Soto?

Natural beauty is on display at Sunrise Lake Beach, Big River and Big Lake. A couple of additional sights to add to your itinerary are Washington State Park and Redfield's Flea Market. Take a look at what more there is to see and do in Expedia's De Soto guide.

What's the seasonal weather like in De Soto?

The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for De Soto is 1181 mm.

Where is the best place to stay in De Soto?

Pear Tree Inn St. Louis Arnold, located 23.1 mi (37.2 km) from the heart of De Soto, is a top choice for your stay, based on our traveller data. Other good options for your trip to the area are Baymont Inn and Suites by Wyndham Farmington, MO and Comfort Inn Festus - St Louis South. See all available top hotels, or vacation rentals in De Soto.

De Soto hotels from HK$426

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in De Soto

Check prices for these dates

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Our top choices for De Soto hotels

1. Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

2. Hampton Inn & Suites By Hilton Festus

3. La Quinta Inn & Suites by Wyndham Festus - St. Louis South

4. Comfort Inn Festus - St Louis South

5. Baymont by Wyndham Festus

6. Drury Inn & Suites St. Louis Arnold

7. Pear Tree Inn St. Louis Arnold

8. Hampton Inn Farmington

9. Super 8 by Wyndham Pevely

10. Crown Pointe Lodge, BW Signature Collection

11. Holiday Inn Express & Suites Farmington by IHG

12. Days Inn & Suites By Wyndham Festus

13. Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

14. Motel 6 Bonne Terre, MO

15. Baymont Inn and Suites by Wyndham Farmington, MO

16. Corner George Inn Bed & Breakfast

17. Quality Inn Farmington

18. WoodSpring Suites St. Louis Arnold

19. Super 8 by Wyndham Bonne Terre

20. The Conner House B&B

Stay near popular De Soto attractions

Eastside Community Park

Learn more about De Soto

Frequently Asked Questions

What are some of the best holiday rentals that De Soto has to offer?

If I need to cancel my hotel reservation in De Soto, will I receive a refund?

What's the best dog-friendly accommodation option in De Soto?

What are some accommodation options with pools in De Soto?

What is staying in De Soto like?

What should I see while I'm in De Soto?

What's the seasonal weather like in De Soto?

Where is the best place to stay in De Soto?