Defiance Vacation Homes

A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

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Our top choices for Defiance holiday homes

A porch with two turquoise Adirondack chairs and a small table, surrounded by well-maintained greenery and a white house with black shutters.

1. WELCOME TO THE OWL'S NEST - 2 BEDROOM HOME IN AUGUSTA, WINERIES & THE KATY TRAIL

Augusta

Samantha E.

HK$2,290 total

includes taxes & fees

9 Sept - 10 Sept

A spacious living area with a high ceiling, wooden beams, a fireplace, a dining area, and a cozy seating arrangement.

2. 3+ acres, fast wi-fi, garage parking, Koi pond

Wildwood

Jennifer M.

HK$3,016 total

includes taxes & fees

9 Sept - 10 Sept

3. Historic Craftsman • Hot Tub • Walk to Wineries • Katy Trail

AUGUSTA

"We were in town for a wedding, and found this house to stay in. It was perfect!! The little town was adorable and fun to walk the dogs through. The hot tub was obviously a nice plus. The grill was nice and had plenty of propane. No complaints at all! We even added another night to our stay to enjoy it longer. The Miss Augusta riverboat cruise was fun! The wineries were obviously fun also. We really enjoyed picking apples at the orchard too. We really wanted to try the restaurant right down the...

Lola W.

HK$3,208 total

includes taxes & fees

9 Sept - 10 Sept

A kitchen with a view to a patio, a refrigerator, and a trash can.

4. Private Entry Basement Suite • Pond & Farm View • Pet Friendly • St Peters

St. Peters

Ruth R.

HK$2,045 total

includes taxes & fees

9 Sept - 10 Sept

A dining table with a vase of flowers, black chairs, and a window with a view of trees.

5. Private 8 acre Ranch backs to 1850 wooded acre Missouri conservation reservation

Wildwood

Bruce L.

HK$3,914 total

includes taxes & fees

9 Sept - 10 Sept

A two-story house with a covered porch, a stone facade, and a well-maintained lawn.

6. Kid and pet friendly 2 nd floor duplex

Pacific

Jason T.

HK$1,550 total

includes taxes & fees

9 Sept - 10 Sept

A two-story house with a covered porch, stone exterior, and a large tree in the foreground.

7. Pet and kid friendly duplex with 2 bedrooms

Pacific

Jason R.

HK$1,529 total

includes taxes & fees

21 Sept - 22 Sept

A spacious kitchen with white cabinets, a central island with bar stools, a stainless steel refrigerator, and a microwave.

8. Spacious, 3 bedroom home, finished basement on quiet court

St. Peters

Leanne S.

HK$2,871 total

includes taxes & fees

15 Sept - 16 Sept

A wooden pergola with a 'GARDEN' sign, a pathway leading to a house, and a lush garden with various plants and flowers.

9. Cozy little house blocks from the Park & Fair Grounds.

Washington

Blair O.

HK$1,989 total

includes taxes & fees

9 Sept - 10 Sept

A modern kitchen with white cabinets, stainless steel appliances, and a wooden dining table.

10. Centrally located, spacious 4 bdrm, on quiet Ct

O'Fallon

William M.

HK$3,961 total

includes taxes & fees

14 Sept - 15 Sept

A house with a red door, a welcome sign, and numbered steps leading to the entrance.

11. Home in the heart of downtown Pacific. Walkable shops and restaurants

Pacific

James A.

HK$2,059 total

includes taxes & fees

9 Sept - 10 Sept

A modern living room with a grey sofa, a coffee table, and a patterned rug. There is a dining area with yellow chairs and a small table.

12. Cozy Historic WashMo home

Washington

melissa G.

HK$2,392 total

includes taxes & fees

15 Sept - 16 Sept

13. Cambrook - 5 bedrm - 8 Beds 2 bathrooms

Saint Charles

HK$2,953 total

includes taxes & fees

28 Sept - 29 Sept

A hotel room with a large bed, a nightstand with a lamp, a painting on the wall, and a window with curtains.

14. Pet-Friendly 2BR Townhome | Workspace

O Fallon

Jen D.

HK$2,983 total

includes taxes & fees

14 Sept - 15 Sept

A bedroom with two beds, a ceiling fan, and a window with blue curtains.

15. 4BR Marvel House Game Room, Sleeps 14

St. Peters

Ann S.

HK$3,830 total

includes taxes & fees

14 Sept - 15 Sept

A modern kitchen with white cabinets, stainless steel appliances, and a wooden floor.

16. Charming 3-bedroom house in delightful Ballwin and basement is not included

Ballwin

Stephanie N.

HK$2,070 total

includes taxes & fees

9 Sept - 10 Sept

A modern kitchen with white cabinets, a central island, and pendant lighting.

17. Washington Guest House

Washington

Kyle K.

HK$2,841 total

includes taxes & fees

9 Sept - 10 Sept

A living room with a glass coffee table, two beige sofas, a wooden cabinet, and a ceiling fan.

18. Spacious 5-bedroom house in serene O'Fallon with AC

O'Fallon

RAMONA O E.

HK$4,788 total

includes taxes & fees

9 Sept - 10 Sept

A room with a mural depicting St. Louis landmarks, a red table tennis table, and a door.

19. 4BR Fenced Yard, Pet-Friendly, Games & Ping Pong

Ballwin

Holly R.

HK$3,465 total

includes taxes & fees

9 Sept - 10 Sept

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Top Defiance Hotel Reviews

Hollywood Casino & Hotel St. Louis

8/10 Good

"Travelled to St Louis for a quick trip. Had an early flight and went straight to hotel to request an early check in. Upon arrival I requested a 2 hour early check in. The lady at the check in desk was rude and immediately shut me down. So, we gambled, ate lunch and waited. 2 hours before check-in, I noticed plotters were checking in and getting keys, so I approached a gentleman and asked him if I could also check in, which he did accommodate. Was grateful for him. So, my first impression was not the best."

Ameristar Casino Resort and Spa

10/10 Excellent

"I'll tell you what. I visited the Ameristar for a fun weekend reunion with a long time college friend I hadn't seen in 30 years. We had plans to see the city, eat Italian on the Hill, go see the arch, see the city museum. But no...we left one time to go to a diner around the corner for breakfast and realized we had no desire to leave the hotel again. The food was amazing, the people (most likely regulars) were hilarious and fun. The pool was to die for. The bartenders at the pool were amazing and fun. We went to see the cover band at one of the bars on Saturday night and the place was PACKED. I think people were there just to go see them. Costumes, mullet wigs, 90's hair band...it was so fun. Will most DEFINITELY be back. Can't say enough good things. The rooms were HUGE and lovely. There were 17 pillows to choose from for your firmness desire (okay, maybe just 4 but still...). We had a blast."

Drury Inn & Suites St. Louis St. Peters

8/10 Good

"It was good, everything was as expected.. breakfast and dinner times could be longer as it’s a hotel, with a lot of people, as people just sit in the minimal amount of tables .. other than the fact that they offer amenities, they definitely need more room and obviously more food and waffle makers"

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