A large white cable-stayed bridge over a river with green supports and a forested landscape in the background.

Des Moines County Holiday Rentals

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Our top choices for Des Moines County holiday rentals

A modern kitchen with a central island, bar stools, and a large window offering a view of the outdoors.

1. Brand New Spacious 2 BR Downtown Burlington! Unit 301S

Brand New Spacious 2 BR Downtown Burlington! Unit 301S
Burlington
9.8 out of 10, Exceptional, (18 reviews)
"Great location! Check in easy and check out process simple. Great place for a fun weekend!"
United States
Roxane K.
The price is HK$992
HK$2,525 total
includes taxes & fees
27 Oct - 28 Oct
Brand New Spacious 2 BR Downtown Burlington! Unit 301S
A covered outdoor seating area with a wooden deck, a sofa, and a table.

2. Mississippi Muse - 1BR Near Downtown, Outdoor lounge, fire pit & grill

Mississippi Muse - 1BR Near Downtown, Outdoor lounge, fire pit & grill
Burlington
10.0 out of 10, Exceptional, (5 reviews)
"Amazing place with a phenomenal host! Very attentive to the small details and making you feel welcome and at home!"
United States
David B.
The price is HK$980
HK$2,231 total
includes taxes & fees
28 Oct - 29 Oct
Mississippi Muse - 1BR Near Downtown, Outdoor lounge, fire pit & grill
A modern kitchen with wooden cabinets, a black refrigerator, a stainless steel sink, and a bar area with two bar stools.

3. Brand New SPACIOUS 2 BR Downtown Burlington! Unit 302N

Brand New SPACIOUS 2 BR Downtown Burlington! Unit 302N
Burlington
10.0 out of 10, Exceptional, (23 reviews)
"This was our second stay and can’t wait to stay again. Super clean and spacious."
United States
Heather H.
The price is HK$992
HK$2,525 total
includes taxes & fees
27 Oct - 28 Oct
Brand New SPACIOUS 2 BR Downtown Burlington! Unit 302N
A row of single-family homes with a well-maintained lawn and a tree in the foreground.

4. Nauvoo Vacation Villas & Condos

Nauvoo Vacation Villas & Condos
3.0 star property
Nauvoo
9.8 out of 10, Exceptional, (459 reviews)
"A great place to stay!"
United States
Renae
The price is HK$1,129
HK$1,197 total
includes taxes & fees
27 Oct - 28 Oct
Nauvoo Vacation Villas & Condos
A modern living room with a leather sofa, a wooden coffee table, and a blue armchair.

5. Idyllic Biggsville Vacation Rental: 10 Mi to River

Idyllic Biggsville Vacation Rental: 10 Mi to River
3.0 star property
Biggsville
10.0 out of 10, Exceptional, (3 reviews)
"Rooms were clean and the bed was comfortable! Highly recommend this rental. "
United States
Brennan
The price is HK$1,176
HK$1,755 total
includes taxes & fees
1 Nov - 2 Nov
Idyllic Biggsville Vacation Rental: 10 Mi to River
A living room with a red sofa, a glass coffee table, and a view of a lake through large sliding glass doors.

6. Riverside Waterfront on the Mississippi River

Riverside Waterfront on the Mississippi River
Pontoosuc
9.8 out of 10, Exceptional, (28 reviews)
"Great place good location "
United States
willmer m.
The price is HK$1,200
HK$2,394 total
includes taxes & fees
17 Nov - 18 Nov
Riverside Waterfront on the Mississippi River
A two-story house with a front porch, a visible front door, and a staircase leading to the entrance.

7. Mulholland Garden Apartment

Mulholland Garden Apartment
Nauvoo
9.2 out of 10, Wonderful, (50 reviews)
"Well decorated and clean. Comfy bed. Close to city attractions."
United States
Adam
The price is HK$593
HK$1,085 total
includes taxes & fees
2 Nov - 3 Nov
Mulholland Garden Apartment
A modern living room with a leather sofa, a wooden coffee table, and a blue armchair.

8. Idyllic Biggsville Vacation Rental: 10 Mi to River

Idyllic Biggsville Vacation Rental: 10 Mi to River
Biggsville
10.0 out of 10, Exceptional, (3 reviews)
"We enjoyed our peaceful stay in this clean, beautiful vacation rental. Perfect for a weekend getaway. "
United States
Lisa S.
The price is HK$863
HK$1,787 total
includes taxes & fees
1 Nov - 2 Nov
Idyllic Biggsville Vacation Rental: 10 Mi to River
A living room with a grey sofa, a coffee table, a TV, a bookshelf, and a plant.

9. Stay in this Unique SE Iowa Apt

Stay in this Unique SE Iowa Apt
Fort Madison
10.0 out of 10, Exceptional, (19 reviews)
"Great place to stay."
United States
Nicholas H.
The price is HK$483
HK$1,156 total
includes taxes & fees
27 Oct - 28 Oct
Stay in this Unique SE Iowa Apt
A rustic brick interior with a fireplace, a wooden stool, and a checkered rug.

10. Experience Beautiful Pioneer Home In Nauvoo!

Experience Beautiful Pioneer Home In Nauvoo!
Nauvoo
9.8 out of 10, Exceptional, (92 reviews)
"We had a great stay!"
United States
Darin B.
The price is HK$1,490
HK$2,976 total
includes taxes & fees
27 Oct - 28 Oct
Experience Beautiful Pioneer Home In Nauvoo!
A spacious living area with a dining table and chairs, a television, and a fireplace.

11. River’s Edge Retro: Cozy Slumber, Grand Views

River’s Edge Retro: Cozy Slumber, Grand Views
Niota
7.0 out of 10, Good, (2 reviews)
"To be very honest the property is not what I expected from the listing. However, after getting settled in and the excellent communication with the host, the 6-week stay was very pleasant. The host was wonderful and checked on us on a regular basis. Host was very quick to fix any issues and was also very quick in all responses. They made us feel welcome. The neighbors were friendly and helpful. I would definitely recommend this property to someone who is looking for a reasonably priced home to...
United States
David B.
The price is HK$776
HK$1,504 total
includes taxes & fees
27 Oct - 28 Oct
River’s Edge Retro: Cozy Slumber, Grand Views
A single-story house with a front porch, a sliding glass door, and a small deck area.

12. Historic 1840s Lamoreaux House / Modern Addition

Historic 1840s Lamoreaux House / Modern Addition
Nauvoo
9.6 out of 10, Exceptional, (27 reviews)
"Plenty of space for our family. Good location."
United States
Chelsea S.
The price is HK$1,941
HK$2,830 total
includes taxes & fees
30 Oct - 31 Oct
Historic 1840s Lamoreaux House / Modern Addition
A cozy living room with a wooden floor, a round rug, and a large chandelier. There are bookshelves and a television on the right side.

13. A four bedroom hobbit hole style home five minutes from historic Nauvoo Illinois

A four bedroom hobbit hole style home five minutes from historic Nauvoo Illinois
Nauvoo
10.0 out of 10, Exceptional, (24 reviews)
"This was by far a very unique enjoyable stay! We enjoyed the atmosphere and the cleanliness of the place and oh - what a friendly cat!!! Would definitely stay again! Aldo enjoyed reading the little notes scattered throughout!"
United States
Linda B.
The price is HK$2,510
HK$3,167 total
includes taxes & fees
27 Oct - 28 Oct
A four bedroom hobbit hole style home five minutes from historic Nauvoo Illinois
A house with a fire pit in the backyard, a porch, and a blue chair.

14. Cozy House

Cozy House
Biggsville
10.0 out of 10, Exceptional, (8 reviews)
"Great place for our needs!"
United States
jdl j.
The price is HK$671
HK$1,376 total
includes taxes & fees
27 Oct - 28 Oct
Cozy House
A deck overlooking a body of water with a sunset in the background.

15. View Nauvoo and the Mighty Mississippi/Sidon

View Nauvoo and the Mighty Mississippi/Sidon
Nauvoo
9.6 out of 10, Exceptional, (44 reviews)
"Castle home was amazing! View of the river is incredible. So much room with extra fans and pillows. We loved our stay!!"
United States
Chris P.
The price is HK$751
HK$2,325 total
includes taxes & fees
27 Oct - 28 Oct
View Nauvoo and the Mighty Mississippi/Sidon
A living room with a sectional sofa, a round coffee table, a lamp, a clock, and a view of the outdoors through a window.

16. Nauvoo Windmill Farmhouse 10-12 people

Nauvoo Windmill Farmhouse 10-12 people
Niota
10.0 out of 10, Exceptional, (22 reviews)
"Great stay very peaceful "
United States
larry r.
The price is HK$980
HK$1,762 total
includes taxes & fees
27 Oct - 28 Oct
Nauvoo Windmill Farmhouse 10-12 people
A kitchen with wooden cabinets, a black refrigerator, a microwave, and a dining table with chairs.

17. Full family APT in Nauvoo-Walking distance to Temple and Historic Nauvoo

Full family APT in Nauvoo-Walking distance to Temple and Historic Nauvoo
Nauvoo
9.6 out of 10, Exceptional, (28 reviews)
"Everything was fabulous it worked out perfect for what we needed"
United States
Marion
The price is HK$882
HK$1,631 total
includes taxes & fees
27 Oct - 28 Oct
Full family APT in Nauvoo-Walking distance to Temple and Historic Nauvoo
A living room with a grey sectional sofa, a blue sofa with floral cushions, a patterned rug, and a radiator.

18. Charming 3-bedroom apartment with WiFi, AC in welcoming Historic Nauvoo.

Charming 3-bedroom apartment with WiFi, AC in welcoming Historic Nauvoo.
Nauvoo
10.0 out of 10, Exceptional, (11 reviews)
"So close to the temple and other historical sites! Unique experience for sure."
United States
Ryan
The price is HK$353
HK$997 total
includes taxes & fees
1 Nov - 2 Nov
Charming 3-bedroom apartment with WiFi, AC in welcoming Historic Nauvoo.
A small building with a red roof, surrounded by dense greenery and trees.

19. Hayfield Cabin

Hayfield Cabin
Niota
6.8 out of 10, (5 reviews)
"It looked like someone was living there. And saw someone lurking around the outside of the cabin. "
United States
Anthony P.
The price is HK$416
HK$899 total
includes taxes & fees
27 Oct - 28 Oct
Hayfield Cabin
A room with a wooden floor, a fireplace with a mantel, a door with glass panels, and a framed painting on the wall.

20. Grand Victorian on the Mississippi

Grand Victorian on the Mississippi
Fort Madison
9.8 out of 10, Exceptional, (34 reviews)
"Really fun house, with antiques and a lovely ambiance!"
United States
Lauren O.
The price is HK$1,521
HK$3,408 total
includes taxes & fees
28 Oct - 29 Oct
Grand Victorian on the Mississippi
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Des Moines County Hotel Reviews

Hampton Inn & Suites Burlington

Hampton Inn & Suites Burlington

10/10 Excellent
"Clean room, well-lit parking lot, helpful staff"
Alexander 1-night trip
Posted 5 hours ago
Hampton Inn & Suites Burlington