Durham Vacation Homes

A cityscape with historic buildings, a baseball field, a pedestrian street, and modern architecture.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

In two weeks

In two months

In three months

In four months

Our top choices for Durham holiday homes

A bedroom with a bed, wooden floor, ceiling fan, windows, and a dresser.

1. Chic Craftsman, Walk Downtown

Downtown Durham

Elizabeth S.

HK$1,388 total

includes taxes & fees

21 Oct - 22 Oct

A wooden house entrance with a red door, a mailbox, and a potted plant.

2. Historic Duplex with Patio

Downtown Durham

Joanne O.

HK$1,326 total

includes taxes & fees

21 Oct - 22 Oct

A wooden deck with a white door leading to a room with a television and a window with blinds.

3. Duke Snuggle Bunker

Durham

Jasper R.

HK$1,844 total

includes taxes & fees

21 Oct - 22 Oct

A bedroom with a bed, a ceiling fan, a nightstand, a cabinet, and a door.

4. Cozy Bungalow near Duke & Dining, Walkable Area

Durham

Emily T.

HK$2,377 total

includes taxes & fees

26 Oct - 27 Oct

What's more luxurious than velvet + fresh linens? This queen-sized bed features a velvet frame and soft, deep mattress - great for a great night's sleep.

5. Cottage with Yard, Mins to Duke

Durham

Dale C.

HK$2,539 total

includes taxes & fees

8 Nov - 9 Nov

A covered outdoor area with a table and chairs, surrounded by a wooden deck and a view of dense greenery.

6. 2BR Urban Retreat, Deck, Near Downtown Durham

Durham

HK$6,138 total

includes taxes & fees

26 Oct - 27 Oct

A bedroom with a large bed, a patterned rug, a desk with a lamp, and a view of the outside.

7. New & Renovated Charming Bungalow near DT Durham

Trinity Park

Kelsey G.

HK$2,269 total

includes taxes & fees

26 Oct - 27 Oct

A modern kitchen with stainless steel appliances, a dining table with chairs, and a potted plant.

8. 2 BR King Bed Near Duke Hospital & Campus

Durham

Janet J.

HK$2,441 total

includes taxes & fees

21 Oct - 22 Oct

A black front door with the number 1305, a small window above it, and a potted plant with red flowers in front.

9. Cozy Bull City Home1.5 mi to Duke Dog friendly

Forest Hills

Amanda R.

HK$3,235 total

includes taxes & fees

26 Oct - 27 Oct

A modern kitchen with white cabinetry, a wooden door, and a dining area with a white table and green chairs.

10. Designer Garden Home Downtown

Downtown Durham

Dan H.

HK$2,408 total

includes taxes & fees

26 Oct - 27 Oct

A house with a porch, a red door, and a mailbox.

11. Vintage Cottage less than 3 mi from Duke Hospital

Forest Hills

Desiree D.

HK$3,011 total

includes taxes & fees

26 Oct - 27 Oct

A modern kitchen with wooden cabinets, a stainless steel refrigerator, a marble countertop, and a central island with food and drinks.

12. Spacious Open-Concept Durham Home

Durham

Tammy T.

HK$2,246 total

includes taxes & fees

26 Oct - 27 Oct

A white door with a glass panel, a keyhole, and a view of a kitchen with cabinets and a countertop.

13. New & Renovated MCM Main Level Duplex 3 mi to Duke Hospital

Durham

HK$2,821 total

includes taxes & fees

25 Oct - 26 Oct

A modern kitchen with white cabinets, a large island, stainless steel appliances, and a dining area with a table and chairs.

14. COZY SUN FILLED HOME / MODERN VILLA NEAR DOWNTOWN

Durham

Garret P.

HK$3,198 total

includes taxes & fees

28 Oct - 29 Oct

A dining area with a round glass table, two chairs, a bookshelf, and a window with a view of trees.

15. Studio near Duke Univ, Hospital & downtown

Durham

Brian H.

A two-story house with a porch, a brick chimney, and a well-maintained lawn.

16. Historic Craftsman, Walk to Duke

Durham

Christina M.

HK$2,475 total

includes taxes & fees

2 Nov - 3 Nov

A modern hotel room with a flat-screen TV mounted on the wall, a dark wooden desk, and a small table with a basket.

17. Stylish and NEW! Duke~Art Deco

Durham

HK$2,694 total

includes taxes & fees

27 Oct - 28 Oct

A modern kitchen with white cabinets, a stainless steel refrigerator, and a dining area with a white table and chairs.

18. NEW! Scandinavian Cottage in Duke~King Bed

Durham

Andrea L.

HK$2,614 total

includes taxes & fees

26 Oct - 27 Oct

A modern living room with a leather sofa, a coffee table, and a TV on a stand.

19. Duke Hospital House

Durham

Ronnie H.

HK$2,556 total

includes taxes & fees

21 Oct - 22 Oct

A modern living room with a fireplace, leather armchairs, a pink sofa, and a dining area with a kitchen in the background.

20. Adorable home in fantastic location near restaurants and Duke!

Durham

Brie H.

HK$3,363 total

includes taxes & fees

25 Oct - 26 Oct

View all properties

Find holiday rentals that suit your style

Aparthotels

Apartments

Save an average of 15% on thousands of hotels when you're signed in

Top Durham Hotel Reviews

Hilton Durham near Duke University

10/10 Excellent

"Very friendly and accommodating staff! Clean rooms and great location."

DoubleTree Raleigh Durham Airport at Research Triangle Park

8/10 Good

"This Doubletree was in excellent shape. Lobby was inviting, rooms were large enough and clean. Double queen beds were actually full size. Cookies were hot and gooey good. What was missing was coffee. We would have appreciated hot coffee available during the day. Restaurant was closed. We ended up going to a convenience store about three miles away to enjoy the oven warm cookies."

Find out more about Durham