East Prairie

Travel Guide

The Mississippi River near Hannibal, Missouri, USA
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
The price is HK$737 per night from 9 Apr to 10 Apr
HK$737
HK$847 total
9 Apr - 10 Apr
includes taxes & fees
Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...
9.6/10 Exceptional! (1,005 reviews)
Everything was great

Reviewed on 2 Apr 2026

Drury Inn & Suites Sikeston, MO
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
The price is HK$746 per night from 11 Apr to 12 Apr
HK$746
HK$844 total
11 Apr - 12 Apr
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular attractions ...
9/10 Wonderful! (526 reviews)
Yes, breakfast was fresh. Room temperature was comfortable. Overall stay was good. Would stay there again

Reviewed on 31 Mar 2026

Hampton Inn Sikeston
Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

2.5 out of 5
120 S Interstate Drive Sikeston MO
The price is HK$659 per night from 9 Apr to 10 Apr
HK$659
HK$752 total
9 Apr - 10 Apr
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking and a fitness centre. Our guests praise the breakfast and the helpful staff in their reviews. ...
8.4/10 Very Good! (1,002 reviews)
The bed and chair was hard. Will not go back

Reviewed on 30 Mar 2026

Best Western Plus Sikeston I-55
See all 87 properties in East Prairie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Duck Hunting, Fishing or Relaxing Family Vacation

Duck Hunting, Fishing or Relaxing Family Vacation

Hornbeak TN
Stay at this holiday home in Hornbeak. Enjoy a garden, laundry facilities and patios. Popular attractions Willow Towhead and Rat Island are located nearby.
10/10 Exceptional! (227 reviews)
Yes, it was very nice. Will be back for sure. View was awesome. The house was very nice and fully stocked.

Reviewed on 27 Mar 2026

Duck Hunting, Fishing or Relaxing Family Vacation
Come and relax at the Refuge at beautiful Reelfoot Lake!

Come and relax at the Refuge at beautiful Reelfoot Lake!

Hornbeak TN
Enjoy free Wi-Fi, laundry facilities and patios. Popular attractions Willow Towhead and Rat Island are located nearby.
9.4/10 Exceptional! (27 reviews)
We loved The Refuge. We just came down for a weekend fishing trip with our boys, But it would be so perfect for someone who wants to come down with a group of friends, as there's plenty of twin beds. We loved it and would definitely stay again.

Reviewed on 23 Mar 2026

Come and relax at the Refuge at beautiful Reelfoot Lake!
Beautiful Reelfoot Lake

Beautiful Reelfoot Lake

Tiptonville TN
Stay at this holiday home in Tiptonville. Enjoy free Wi-Fi, a garden and laundry facilities. Popular attractions Campbell's Point and Reelfoot Lake State Park ...
10/10 Exceptional! (99 reviews)
Amazing home. Clean, updated, great value for your money. Dock was incredible. There’s really no point to look anywhere else!!

Reviewed on 29 Mar 2026

Beautiful Reelfoot Lake
See all properties in East Prairie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Big Oak Tree State Park

You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.

Big Oak Tree State Park

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