*** Deaconess Guesthouse – Historic Luxury on the Ohio River, Minutes from Louisville & Jeffersonville ***
★ Where History Meets Timeless Luxury
Step into the elegance of the Deaconess Guesthouse, a fully reimagined 1800s landmark that once served as Jeffersonville’s first public hospital. Expertly restored by Charming Vacation Homes, this iconic estate seamlessly combines historic charm with boutique-style comforts. With panoramic Ohio River views and a location just minutes from downtown Louisville, the Bourbon Trail and Jeffersonville’s lively riverfront district, it offers a truly unparalleled setting for your next gathering.
★ Crafted for Groups & Celebrations
With 8 bedrooms and 6 bathrooms spread across four private units, the estate comfortably welcomes up to 24 guests. Whether hosting a family reunion, corporate retreat, wedding party or milestone celebration, the home’s layout offers the perfect blend of shared spaces and private retreats. Every detail—from the expansive living areas to the refined finishes and curated décor—is designed to create an atmosphere of warmth, connection and lasting memories.
★ Signature Features & Amenities
1. Private Hot Tub & Fire Pit – Unwind beneath the stars in your own riverfront oasis
2. Wraparound Porches & Balconies – Start mornings with sunrise views end with evening cocktails
3. Stargazing Dome – A one-of-a-kind retreat, perfect for both kids and adults
4. Ample On-Site Parking – Convenient for large groups, events and VIP transportation (concierge recommendations)
★ A Location Unlike Any Other
- Walk to Downtown Jeffersonville – Explore boutique shops, local dining, and riverfront entertainment
- Just 2.5 Miles to Downtown Louisville – Experience bourbon distilleries, Churchill Downs, world-class museums and live events
- Adventure at Your Doorstep – Enjoy kayaking, biking trails, riverfront concerts and seasonal festivals nearby
★ Your Exclusive Riverfront Escape
From tranquil mornings on the porch to evenings around the fire pit, the Deaconess Guesthouse offers a stay that is both indulgent and inspiring. Its rich history, scenic riverfront setting and luxury amenities make it an extraordinary destination for guests who expect more than just a place to stay.
★ Now Booking for Exclusive Stays & Events
Perfect for:
- Corporate retreats & executive gatherings
- Multi-family vacations
- Wedding parties & milestone celebrations
- Girls’/Guys’ getaways
- Holiday gatherings & festive weekends
Book your stay today and create memories in one of Jeffersonville’s most historic and luxurious riverfront estates.
★ CONVENIENT LOCATION
The house is centrally located and is within a 10-15 minute Uber/Lyft drive to most locations:
- Big Four Walking Bridge (Connecting KY and IN) - 0.4 miles (2 mins)
- Downtown Louisville/ 4th Street Live - 2.4 miles (6 mins)
- KFC Yum Center - 2.3 miles (7 mins)
- Churchill Downs (DERBY) - 7.7 miles (15 mins)
- Waterfront Park - 3.4 miles (9 mins)
- Papa Johns Stadium (Cardinal Stadium) - 6.4 miles (11 mins)
- Kentucky Fairgrounds - 6.5 miles (10 min)
- University of Louisville - 6.5 miles (12 mins)
- Louisville Airport - 8.6 miles (10 mins)
- Kentucky Exposition Center - 6.7 miles (11 mins)
- Kentucky Kingdom - 7.4 miles (13 mins)
- Highland Festival Grounds - 8.5 miles (12 mins)
- Louisville Mega Cavern - 10.2 miles (19 mins)
- UPS Worldport - 11.2 miles (20 mins)
- Ford LAP Plant - 10.9 miles (16 mins)
- Waverly Hills Sanatorium - 17 miles (30 mins)
- Valhalla Golf Club - 19 miles (27 mins)
PROPERTY HIGHLIGHTS
★ Exclusive Riverfront Retreat near downtown Louisville/Jeffersonville: Experience a rare architectural masterpiece where historic elegance meets modern sophistication—perfectly situated just minutes from Louisville/Jeffersonville, New Albany and Clarksville.
★ Prime Ohio Riverfront Setting: Wake up to sweeping river views and step outside to enjoy Jeffersonville’s vibrant downtown dining, boutique shopping, lively festivals, and entertainment—all just a short stroll away.
★ Historic Charm, Modern Luxury: This meticulously restored landmark offers refined interiors, elegant finishes and one-of-a-kind details that create an atmosphere of timeless comfort.
★ Scenic Views & Inviting Spaces: Savor your morning coffee or evening cocktails from covered porches and private balconies overlooking the river’s sparkling waters.
★ Designed for Comfort & Connection: With 8 beautifully appointed bedrooms and 6 designer bathrooms, the home provides light-filled, spacious interiors perfect for relaxation, entertaining and memory-making.
★ Chef-Inspired Living: Four gourmet kitchens, each with premium appliances and upscale touches, set the stage for unforgettable meals and gatherings.
★ Family & Pet Friendly: From cozy nooks and kid-friendly areas to accommodations for pets, every member of your group will feel right at home.
★ Private Outdoor Oasis: Unwind in the hot tub, gather around the fire pit, lounge under the Hyperdome or gazebo, grill outdoors and enjoy lawn games beneath the stars.
★ Entertainment for Every Occasion: Smart Roku TVs in every bedroom, indoor/outdoor games and inviting lounge spaces ensure fun and relaxation in every season.
★ Perfect for Groups & Celebrations: Ideal for reunions, retreats and extended stays—complete with 4 washer/dryer sets, parking for 8 and flexible gathering areas designed to bring people together.
★ Your Riverfront Escape Awaits: Discover the ultimate blend of history, luxury and location—an unforgettable getaway right on the banks of the Ohio River.
★ TOP 2025 UPCOMING EVENTS
-Kentucky Bourbon Festival 2025: Sep 5-7th, 2025
-Bourbon & Beyond: Sept 11-14th, 2025
-Louder than Life: Sept 18-21st, 2025
-Jack O’ Lantern Spectacular: Oct 2025
-Halloween Weekends Louisville South KOA Holiday: Oct 2025
★ OTHER 2025 UPCOMING EVENTS (Including TRADE SHOWS)
-Equipment Expo: Oct 21th to 24th, 2025
-North American International Livestock Exposition: Nov 6th to 20th, 2025
NOTE:
1) Must be 25 or older to book.
2) Please review house rules before booking. Rental Agreement & Security Hold: Guests must e-sign our rental agreement and Must submit a $500 off-platform security hold that will be collected upon signing rental agreement but it will not be placed until 2 days prior to arrival and released 7 days after departure, if no damages are reported. Please note we are API Connected to a hotel-style software called OwnerRez to safely and securely take off-platform security deposits.
3) *** STRICT CANCELLATION for DERBY/ Bourbon & Beyond ***
4) Visitors are not permitted unless you make a special request to the host and receive approval.
5) We have exterior surveillance with voice and recording capabilities of the parking area and front door. They are in place for security of guests and the home. We do NOT have interior cameras nor camera in the backyard.
6) The Dome is not recommended for use during hot summer months. We suggest enjoying the other amenities during warmer months for optimal comfort.
7) We cannot accommodate early check-ins or late check-outs for same-day turnarounds.
8) For days without same-day turnarounds, we offer early check-ins and late check-outs at the following rates: $100 for up to 2 hours, $250 for 2 to 4 hours, and a full day's rate for more than 4 hours.
9) Please note that for cancellations of bookings made on platforms other than Airbnb, a Stripe card processing fee of 3% will be deducted from the total refund.
PLEASE REVIEW THE HOUSE RULES BEFORE BOOKING. THANK YOU !!
