Main Street Hotels

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Our top choices for Main Street hotels

Anchor In Distinctive Waterfront Lodging

Anchor In Distinctive Waterfront Lodging
3.0 star property
9.6 km from Main Street
9.4 out of 10, Exceptional, (1,005 reviews)
"The Anchor In is a lovely hotel with friendly staff and clean, updated rooms. It is very convenient to the ferry and to various dining options in Hyannis. Great place to stay!"
United States
Cynthia
The price is HK$921
HK$1,277 total
includes taxes & fees
20 Jan - 21 Jan
Anchor In Distinctive Waterfront Lodging

Courtyard By Marriott Cape Cod Hyannis

Courtyard By Marriott Cape Cod Hyannis
3.0 star property
9.2 km from Main Street
8.8 out of 10, Excellent, (490 reviews)
"Parking was free and easy, room was very clean and housekeeping service was top notch. "
United States
Maureen
The price is HK$990
HK$1,133 total
includes taxes & fees
25 Jan - 26 Jan
Courtyard By Marriott Cape Cod Hyannis

Courtyard Resort

Courtyard Resort
2.0 star property
8.8 km from Main Street
8.4 out of 10, Very good, (53 reviews)
"It was ok. Best part was it was near everything. "
United States
Kimberly
The price is HK$833
HK$954 total
includes taxes & fees
20 Jan - 21 Jan
Courtyard Resort

Holiday Inn Hyannis by IHG

Holiday Inn Hyannis by IHG
3.0 star property
8.9 km from Main Street
8.2 out of 10, Very good, (984 reviews)
"Nice place"
United States
Linda
The price is HK$889
HK$1,017 total
includes taxes & fees
25 Jan - 26 Jan
Holiday Inn Hyannis by IHG

Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod
2.5 star property
9.4 km from Main Street
8.0 out of 10, Very good, (1,002 reviews)
"Nice hotel had a perfect stay"
United States
David
The price is HK$768
HK$879 total
includes taxes & fees
19 Feb - 20 Feb
Comfort Inn Hyannis - Cape Cod

Hampton Inn & Suites Cape Cod-West Yarmouth

Hampton Inn & Suites Cape Cod-West Yarmouth
2.5 star property
10.7 km from Main Street
8.8 out of 10, Excellent, (1,002 reviews)
"They were excellent. Felt extremely comfortable. Their breakfast was amazing, staff were so friendly!"
United States
Linda
The price is HK$857
HK$981 total
includes taxes & fees
25 Jan - 26 Jan
Hampton Inn & Suites Cape Cod-West Yarmouth

Cape Cod Hotel

Cape Cod Hotel
2.5 star property
8.8 km from Main Street
7.4 out of 10, Good, (1,001 reviews)
"Room was clean and what we needed. Very comfortable. Breakfast options were nice. Pancakes, scrambled eggs, potatoes and a variety of yogurt among a few other danishes. Enjoyed our stay. "
United States
Matthew
The price is HK$765
HK$965 total
includes taxes & fees
25 Jan - 26 Jan
Cape Cod Hotel

The Club at New Seabury

The Club at New Seabury
3.5 star property
10.3 km from Main Street
9.0 out of 10, Wonderful, (345 reviews)
"The place was excellent"
United States
Delia
The price is HK$1,126
HK$1,289 total
includes taxes & fees
20 Jan - 21 Jan
The Club at New Seabury

Hyannis Harbor Hotel

Hyannis Harbor Hotel
3.5 star property
9.1 km from Main Street
8.0 out of 10, Very good, (1,001 reviews)
"Lovely stay! One of the best hotels to stay in Hyannis. "
United States
Mary
The price is HK$857
HK$1,296 total
includes taxes & fees
2 Feb - 3 Feb
Hyannis Harbor Hotel

Doubletree by Hilton Cape Cod - Hyannis

Doubletree by Hilton Cape Cod - Hyannis
4.0 star property
9.8 km from Main Street
8.4 out of 10, Very good, (885 reviews)
"It was a decent stay I can’t complain "
United States
Rony
The price is HK$908
HK$1,039 total
includes taxes & fees
25 Jan - 26 Jan
Doubletree by Hilton Cape Cod - Hyannis

Margaritaville Resort Cape Cod

Margaritaville Resort Cape Cod
4.0 star property
8.7 km from Main Street
8.8 out of 10, Excellent, (429 reviews)
"We are very happy with all the people at margaritaville, they are awesome 💝"
United States
Ewerton
The price is HK$1,160
HK$1,774 total
includes taxes & fees
1 Feb - 2 Feb
Margaritaville Resort Cape Cod

The Cove at Yarmouth by Westgate Resorts

The Cove at Yarmouth by Westgate Resorts
3.0 star property
11.2 km from Main Street
9.2 out of 10, Wonderful, (247 reviews)
"The staff are amazing! Love the amenities - the pool, recreation center, activities for the kids such as windchime arts and crafts. The arcade is always a hit. The Loft makes it so easy to not have to stress about a place to go to for dinner. The Cove is a great place for everyone! "
United States
Lauren
The price is HK$931
HK$1,065 total
includes taxes & fees
20 Jan - 21 Jan
The Cove at Yarmouth by Westgate Resorts

Sea Breeze Inn

Sea Breeze Inn
2.5 star property
7.9 km from Main Street
7.8 out of 10, Good, (193 reviews)
"Nice place to stay "
United States
Kevin
The price is HK$616
HK$705 total
includes taxes & fees
20 Jan - 21 Jan
Sea Breeze Inn

Cape Sands Inn

Cape Sands Inn
2.5 star property
11 km from Main Street
8.2 out of 10, Very good, (1,020 reviews)
"Room was nice and spacious, very clean. Upstairs people was a little loud but other than that the stay was good. Would definitely stay again. "
United States
Celestina
The price is HK$581
HK$665 total
includes taxes & fees
20 Jan - 21 Jan
Cape Sands Inn

The Village Inn Cape Cod

The Village Inn Cape Cod
3.5 star property
14.3 km from Main Street
10.0 out of 10, Exceptional, (224 reviews)
"It was so charming, would definitely stay there again! "
United States
Kyle
The price is HK$1,209
HK$1,383 total
includes taxes & fees
21 Jan - 22 Jan
The Village Inn Cape Cod

Hyannis Plaza Hotel

Hyannis Plaza Hotel
2.5 star property
8.2 km from Main Street
7.0 out of 10, Good, (990 reviews)
"The best staff abd it was clean and beautiful "
United States
Heather
The price is HK$569
HK$730 total
includes taxes & fees
19 Feb - 20 Feb
Hyannis Plaza Hotel

Aiden by Best Western Cape Cod - West Yarmouth

Aiden by Best Western Cape Cod - West Yarmouth
3.0 star property
12.4 km from Main Street
8.0 out of 10, Very good, (1,003 reviews)
"Clean room | Breakfast | Bar | Staff"
United States
Daniel
The price is HK$756
HK$865 total
includes taxes & fees
25 Jan - 26 Jan
Aiden by Best Western Cape Cod - West Yarmouth

Harborside Suites

Harborside Suites
2.0 star property
15.1 km from Main Street
6.6 out of 10, (189 reviews)
"Nice hotel "
United States
Sergio
Harborside Suites

Sandy Neck Motel

Sandy Neck Motel
2.5 star property
12.8 km from Main Street
8.8 out of 10, Excellent, (144 reviews)
"Room was spacious and clean. "
United States
Matthew
Sandy Neck Motel

The Escape Inn

The Escape Inn
2.5 star property
16.5 km from Main Street
9.4 out of 10, Exceptional, (663 reviews)
"Great place"
United States
Karim
The price is HK$626
HK$717 total
includes taxes & fees
20 Jan - 21 Jan
The Escape Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Main Street Hotel Reviews

Hotels near other Main Street attractions

Frequently asked questions

What's the area like around Main Street?
If you're planning to come to the area to visit Main Street, take some time to see the rest of the sights while you're in town. If you're looking for a convenient place to stay, take a look at the 24 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to Main Street?
Long Dell Inn is one of the top choices for your stay based on our traveller data, and this B&B offers free breakfast and free parking. It's located 2.5 mi (4.1 km) from Main Street. Other good choices within 5 miles include The Ocean View and Captain David Kelley House Bed & Breakfast.
How many hotels will I be able to find near Main Street?
Expedia has 24 hotels and other accommodation options within a mile from Main Street.
If I need to cancel the hotel reservation for my stay near Main Street, will I receive a refund?
Yes! The majority of hotel room reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and be given a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to review the best options available near Main Street.
What can I see and do near Main Street?
Study the collections at Centerville Historical Museum, Cahoon Museum of American Art or Toad Hall Classic Sports Car Museum. You can check out the local talent at Cotuit Center for the Arts, Cape Cod Melody Tent and Barnstable Performing Arts Center. Dip your toes in the water at Craigville Beach, Keyes Beach and Dowses Beach.

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