A calm river with clear water, surrounded by dense trees and rocky banks.

O Brien hotels from HK$510

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Check prices for these dates

Tonight
8 Aug - 9 Aug
Tomorrow
9 Aug - 10 Aug
Next weekend
14 Aug - 16 Aug
In two weeks
21 Aug - 23 Aug

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Our top choices for O Brien hotels

Hotel
Breakfast included
Motel
Reserve now, pay later
Pool

1. Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City
Lake City
United States
Justo
HK$816
HK$918 total
includes taxes & fees
30 Aug - 31 Aug
Hampton Inn & Suites Lake City

2. Best Western Plus Lake City

Best Western Plus Lake City
Lake City
United States
James
HK$643
HK$723 total
includes taxes & fees
16 Aug - 17 Aug
Best Western Plus Lake City

3. Tru by Hilton Lake City

Tru by Hilton Lake City
Lake City
United States
Michael
HK$855
HK$962 total
includes taxes & fees
16 Aug - 17 Aug
Tru by Hilton Lake City

4. Super 8 by Wyndham Lake City

Super 8 by Wyndham Lake City
Lake City
United States
Mari
HK$513
HK$578 total
includes taxes & fees
10 Aug - 11 Aug
Super 8 by Wyndham Lake City

5. Comfort Suites Lake City

Comfort Suites Lake City
Lake City
United States
KHAJA
HK$770
HK$866 total
includes taxes & fees
18 Aug - 19 Aug
Comfort Suites Lake City

6. Home2 Suites by Hilton Lake City

Home2 Suites by Hilton Lake City
Lake City
United States
William
HK$960
HK$1,080 total
includes taxes & fees
16 Aug - 17 Aug
Home2 Suites by Hilton Lake City

7. Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City
Lake City
United States
Adoniram
HK$840
HK$945 total
includes taxes & fees
16 Aug - 17 Aug
Fairfield Inn & Suites Lake City

8. Holiday Inn Express & Suites Live Oak by IHG

Holiday Inn Express & Suites Live Oak by IHG
Live Oak
United States
Trisha
HK$824
HK$906 total
includes taxes & fees
30 Aug - 31 Aug
Holiday Inn Express & Suites Live Oak by IHG

9. Holiday Inn & Suites Lake City by IHG

Holiday Inn & Suites Lake City by IHG
Lake City
United States
Renee
HK$761
HK$856 total
includes taxes & fees
16 Aug - 17 Aug
Holiday Inn & Suites Lake City by IHG

10. Americas Best Value Inn Lake City

Americas Best Value Inn Lake City
Lake City
United States
Larissa
HK$508
HK$572 total
includes taxes & fees
10 Aug - 11 Aug
Americas Best Value Inn Lake City

11. La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City
Lake City
United States
Priscilla J
HK$734
HK$826 total
includes taxes & fees
6 Sept - 7 Sept
La Quinta Inn & Suite by Wyndham Lake City

12. Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee
White Springs
United States
william
HK$471
HK$518 total
includes taxes & fees
10 Aug - 11 Aug
Quality Inn White Springs Suwanee

13. Days Inn by Wyndham Lake City I-75

Days Inn by Wyndham Lake City I-75
Lake City
United States
Brizheet
HK$496
HK$558 total
includes taxes & fees
10 Aug - 11 Aug
Days Inn by Wyndham Lake City I-75

14. Cindys Motel

Cindys Motel
Mayo
United States
Diane
HK$688
HK$744 total
includes taxes & fees
10 Aug - 11 Aug
Cindys Motel

15. Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center
Lake City
United States
Pennee
HK$510
HK$574 total
includes taxes & fees
10 Aug - 11 Aug
Motel 6 – Lake City, Fl – Medical Center

16. Palms Garden Inn

Palms Garden Inn
Lake City
United States
Teresa
HK$510
HK$573 total
includes taxes & fees
10 Aug - 11 Aug
Palms Garden Inn

17. The Blanche

The Blanche
Lake City
United States
Brandi
HK$1,165
HK$1,311 total
includes taxes & fees
10 Aug - 11 Aug
The Blanche

18. Quality Inn & Suites Live Oak I-10 Exit 283

Quality Inn & Suites Live Oak I-10 Exit 283
Live Oak
United States
Patricia
HK$656
HK$721 total
includes taxes & fees
19 Aug - 20 Aug
Quality Inn & Suites Live Oak I-10 Exit 283

19. Suwannee River Retreat: Pet Friendly, Private Dock

Suwannee River Retreat: Pet Friendly, Private Dock
Branford
HK$2,526
HK$4,757 total
includes taxes & fees
17 Aug - 18 Aug
Suwannee River Retreat: Pet Friendly, Private Dock

20. Regal Inn

Regal Inn
Lake City
United States
Samuel
HK$487
HK$548 total
includes taxes & fees
12 Aug - 13 Aug
Regal Inn
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Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

See all hotels in O Brien
A calm river surrounded by trees reflecting in the water.

Top O Brien Hotel Reviews

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

10/10 Excellent
"Everything worked great"
Eli 2-night trip
Posted 14 hours ago
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
Tru by Hilton Lake City

Tru by Hilton Lake City

8/10 Good
"Air conditioner was extremely loud."
Jessica 1-night trip
Posted 1 day ago
Tru by Hilton Lake City
Holiday Inn Express & Suites Live Oak by IHG

Holiday Inn Express & Suites Live Oak by IHG

10/10 Excellent
"The rate per night was reasonable, the breakfast was amazing, and unlimited free coffee was prefect, and the staff was very helpful and accommodating when we had an issue after the rain."
Trisha 2-night trip
Posted 6 days ago
Holiday Inn Express & Suites Live Oak by IHG
Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!

8/10 Good
"Christine was absolutely wonderful from beginning to end. She even came by to say hello on our first day. Very responsive. I do wish the river was closer and not quite a small walk because my in laws are elderly and couldn’t enjoy it. The walk to the river is quite tough, hard to get kayaks out to the water, It’s a very steep walk. The ac wouldn’t go any colder than 70. Only one television which is in the livingroom so that was rough. Kitchen and home Fully stocked with all the things we needed and the kids enjoyed the play room. Overall the home and the host was great for the price"
Kristina K. 3-night trip
Posted 1 month ago
Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!
MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY

MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY

10/10 Excellent
"A great get away for Labor Day weekend to do a little jet skiing with friends on the river and visiting all the local springs!"
Heather H. 2-night trip
Posted 1 year ago
MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY

More cheap stays in O Brien

Days Inn by Wyndham Lake City I-10

Days Inn by Wyndham Lake City I-10

3430 N Us Highway 441 Lake City FL
HK$464
HK$522 total
10 Aug - 11 Aug
includes taxes & fees
Days Inn by Wyndham Lake City I-10
Quality Inn Lake City

Quality Inn Lake City

285 Sw Commerce Dr Lake City FL
HK$573
HK$645 total
7 Sept - 8 Sept
includes taxes & fees
Quality Inn Lake City
Best Western Plus Lake City

Best Western Plus Lake City

350 SW Florida Gateway Dr Lake City FL
HK$643
HK$723 total
16 Aug - 17 Aug
includes taxes & fees
Best Western Plus Lake City
Comfort Suites Lake City

Comfort Suites Lake City

3690 W Us Highway 90 Lake City FL
HK$770
HK$866 total
18 Aug - 19 Aug
includes taxes & fees
Comfort Suites Lake City
Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75

15930 Northwest 163rd Lane Alachua FL
HK$830
HK$934 total
17 Aug - 18 Aug
includes taxes & fees
Hampton Inn & Suites Alachua I-75
Tru by Hilton Lake City

Tru by Hilton Lake City

284 NW Centurion Court Lake City FL
HK$855
HK$962 total
16 Aug - 17 Aug
includes taxes & fees
9.2/10 Wonderful! (1,012 reviews)
Tru by Hilton Lake City

Frequently asked questions

Where is the best place to stay in O Brien?
Best Western Plus Lake City, located 17.9 mi (28.8 km) from the heart of O Brien, is a top choice for your stay, based on our traveller data. Two other options for your trip to the area are Holiday Inn Express & Suites Alachua - Gainesville Area by IHG and La Quinta Inn & Suite by Wyndham Lake City. See all available top hotels, or vacation rentals in O Brien.
What are some of the best holiday rentals that O Brien has to offer?
Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!: This highly rated holiday home rental in O Brien is located on the beach, and has a balcony, a garden and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. You and your friends and family can relax into your holiday with amenities such as a selection of games. See all vacation rentals in O Brien.
If I need to cancel my hotel reservation in O Brien, will I receive a refund?
Yes! You'll find that most hotel bookings are refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.
What are some accommodation options with pools in O Brien?
How is it to stay in O Brien?
Visitors to O Brien will definitely find plenty to explore and enjoy. In O Brien, there are 9 hotels and other accommodation options to choose from. Find out more about O Brien.
What are the top places to visit in O Brien?
Natural beauty is on display at Suwannee River, Ichetucknee River and Ichetucknee Springs State Park. You'll also find Troy Spring State Park and Wes Skiles Peacock Springs State Park in the area. Take a look at what more there is to see and do in Expedia's O Brien guide.
What's the seasonal weather in O Brien?
The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 14°C. Average annual precipitation for O Brien is 1278 mm.

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