Perryville Holiday Rentals

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Check prices for these dates

In two weeks
26 Dec - 28 Dec
In two months
6 Feb - 8 Feb
In three months
6 Mar - 8 Mar
In four months
3 Apr - 5 Apr

Our top choices for Perryville holiday rentals

Outdoor spa tub
Hot Tub & Creek Views: Secluded Perryville Cabin

Cabin in Perryville

Hot Tub & Creek Views: Secluded Perryville Cabin
9.8 out of 10, Exceptional, (8)
"We enjoyed our stay! Peaceful and relaxing.John and Bambi"
United States
Bambi and John B.
Hot Tub & Creek Views: Secluded Perryville Cabin
Property grounds
TreeLoft at BaseCamp

Cabin in Perryville

TreeLoft at BaseCamp
2.0 star property
10.0 out of 10, Exceptional, (5)
"This place is perfect if you want a private upscale experience that is immersed in natural beauty. The treehouse is luxurious and so comfortable. We loved every minute of our stay. "
United States
joel r.
The price is HK$3,104
HK$4,775 total
includes taxes & fees
20 Dec - 21 Dec
TreeLoft at BaseCamp
Property grounds
New! Luxury Meets Nature - TreeRise at BaseCamp

Cabin in Perryville

New! Luxury Meets Nature - TreeRise at BaseCamp
2.0 star property
10.0 out of 10, Exceptional, (1)
"Our visit was short but so special. Waylon and Kaci have created a sweet haven of rest in the woods of Missouri. We so appreciated the chance to unplug for a bit. Can’t recommend enough! "
United States
Amber S.
New! Luxury Meets Nature - TreeRise at BaseCamp
Full-sized fridge, microwave, oven, stovetop
Urban Lofts

Aparthotel in Perryville

Urban Lofts
3.0 star property
9.2 out of 10, Wonderful, (17)
"Great place to stay! "
United States
Eric
Urban Lofts
Interior
Urban Loft #1 RED · Urban Loft Downtown above BrewCo & Restaurant

Apartment in Perryville

Urban Loft #1 RED · Urban Loft Downtown above BrewCo & Restaurant
10.0 out of 10, Exceptional, (1)
"Everything was perfect!"
United States
Thor L.
The price is HK$1,517
HK$2,457 total
includes taxes & fees
7 Jan - 8 Jan 2026
Urban Loft #1 RED · Urban Loft Downtown above BrewCo & Restaurant
Interior
5 Star Cabin LUXURY AMMENITIES W/POOL HTUB close to WINE TRAIL, HIKING, FISHING

Holiday Home in Murphysboro

5 Star Cabin LUXURY AMMENITIES W/POOL HTUB close to WINE TRAIL, HIKING, FISHING
10.0 out of 10, Exceptional, (16)
"We are a Bunco group who try to take a trip together every year. This year there were 8 of us. We spent a day enjoying the pool and another day shuttling on the wine trail. The house was a perfect place to hang in the evenings. "
United States
Ann F.
5 Star Cabin LUXURY AMMENITIES W/POOL HTUB close to WINE TRAIL, HIKING, FISHING
Property grounds
Micro house cabin located near Silver Mines Recreation Area.

Cabin in Fredericktown

Micro house cabin located near Silver Mines Recreation Area.
10.0 out of 10, Exceptional, (78)
"This was my second visit and am planning to return again someday. Very quiet and cozy. "
United States
eric y.
Micro house cabin located near Silver Mines Recreation Area.
Exterior
Beautiful Modern Loft In Wine Country!

Apartment in Ste. Genevieve

Beautiful Modern Loft In Wine Country!
10.0 out of 10, Exceptional, (271)
"Loved our stay here! Thoughtful amenities on a beautiful property. Great communication with host. "
United States
Elsie H.
The price is HK$1,151
HK$1,406 total
includes taxes & fees
22 Dec - 23 Dec
Beautiful Modern Loft In Wine Country!
Outdoor dining
Beautiful location in the secluded woods

Holiday Home in Pomona

Beautiful location in the secluded woods
10.0 out of 10, Exceptional, (60)
"It was very nice and clean. We really enjoyed staying there. We would love to rent this place again. "
United States
susan B.
The price is HK$655
HK$1,271 total
includes taxes & fees
12 Dec - 13 Dec
Beautiful location in the secluded woods
Exterior
Sunset Ridge - Peaceful 3-bedroom house with WiFi and AC in lovely Weingarten.

Holiday Home in New Offenburg

Sunset Ridge - Peaceful 3-bedroom house with WiFi and AC in lovely Weingarten.
10.0 out of 10, Exceptional, (5)
"Relaxing setting between Farmington and St Genevieve. Both towns are rich in history and have small town charm. "
United States
Tim M.
The price is HK$1,167
HK$2,333 total
includes taxes & fees
15 Dec - 16 Dec
Sunset Ridge - Peaceful 3-bedroom house with WiFi and AC in lovely Weingarten.
Bar (on property)
Big Sky Cabin! Hot Tub! On the Wine Trail! Fire Pit! Pool Table! Large Deck!

Cabin in Alto Pass

Big Sky Cabin! Hot Tub! On the Wine Trail! Fire Pit! Pool Table! Large Deck!
9.8 out of 10, Exceptional, (175)
"Place was great "
United States
Ernest S.
Big Sky Cabin! Hot Tub! On the Wine Trail! Fire Pit! Pool Table! Large Deck!
Property grounds
"Little Brick House on Main (1865)”

Holiday Home in Ste. Genevieve

"Little Brick House on Main (1865)”
10.0 out of 10, Exceptional, (63)
"Great place to stay!"
United States
Lettitia B.
The price is HK$924
HK$1,235 total
includes taxes & fees
17 Dec - 18 Dec
"Little Brick House on Main (1865)”
Microwave, oven, stovetop, dishwasher
Greenway Getaway~Charming 3-bedroom, 3 BA home in the heart of Jackson, Missouri

Holiday Home in Jackson

Greenway Getaway~Charming 3-bedroom, 3 BA home in the heart of Jackson, Missouri
Greenway Getaway~Charming 3-bedroom, 3 BA home in the heart of Jackson, Missouri
Private kitchen
Historic House in heart of Altenburg

Holiday Home in Altenburg

Historic House in heart of Altenburg
2.0 star property
10.0 out of 10, Exceptional, (1)
"Great place to stay Quite and clean"
United States
Catherine M.
Historic House in heart of Altenburg
Outdoor dining
Gorgeous 5 Bedroom Log Home Less Than 5 Minutes From Chaumette And Charleville.

Cabin in Ste. Genevieve

Gorgeous 5 Bedroom Log Home Less Than 5 Minutes From Chaumette And Charleville.
10.0 out of 10, Exceptional, (58)
"Clean spacious quiet( except for the dogs barking) kitchen pans are terrible."
United States
Barb S.
The price is HK$2,100
HK$2,762 total
includes taxes & fees
23 Dec - 24 Dec
Gorgeous 5 Bedroom Log Home Less Than 5 Minutes From Chaumette And Charleville.
Living area
The Lab! Come stay in our brand new space.

Apartment in Murphysboro

The Lab! Come stay in our brand new space.
9.4 out of 10, Exceptional, (19)
"We were in town for a wedding, and this was the perfect place to stay. The Vrbo was well-stocked with everything you may need and very clean."
United States
Sean G.
The price is HK$945
HK$1,579 total
includes taxes & fees
17 Dec - 18 Dec
The Lab! Come stay in our brand new space.
Living area
St Francis River: The Blue Yurt and Hot Tub

Cabin in Fredericktown

St Francis River: The Blue Yurt and Hot Tub
8.8 out of 10, Excellent, (18)
"Loved this rental - great property!"
United States
Julie S.
The price is HK$974
HK$1,602 total
includes taxes & fees
14 Dec - 15 Dec
St Francis River: The Blue Yurt and Hot Tub
Property grounds
Newly remodeled house minutes away from downtown, golf courses + BIG back yard

Holiday Home in Farmington

Newly remodeled house minutes away from downtown, golf courses + BIG back yard
2.0 star property
9.8 out of 10, Exceptional, (20)
"very nice house and good location . had so many things to enjoy"
United States
Peter V.
The price is HK$895
HK$1,764 total
includes taxes & fees
11 Jan - 12 Jan 2026
Newly remodeled house minutes away from downtown, golf courses + BIG back yard
Fridge, microwave, oven, stovetop
Relax in the country at Countryside Villas! - Villa A

Apartment in Jackson

Relax in the country at Countryside Villas! - Villa A
10.0 out of 10, Exceptional, (33)
"Great place to stay, felt like home away from home. "
United States
Brittany
The price is HK$1,167
HK$1,422 total
includes taxes & fees
11 Jan - 12 Jan 2026
Relax in the country at Countryside Villas! - Villa A
Interior
Murphysboro Retreat w/ Deck Near Kinkaid Lake!

Apartment in Murphysboro

Murphysboro Retreat w/ Deck Near Kinkaid Lake!
3.0 star property
10.0 out of 10, Exceptional, (1)
"This is a very clean and nice apartment within a very close drive to the Kinkaid boat launch. Easy to locate and can fit a car with a boat in tow no problem. This spot was also much more quiet than the campground or RV spots nearby. They have a great porch and a grill and we didn’t bring something for it which made me sad. "
United States
Ross
Murphysboro Retreat w/ Deck Near Kinkaid Lake!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Perryville Hotel Reviews

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

10/10 Excellent
"All staff members were outgoing and friendly, rooms very clean, bathrooms. Lean. Their breakfast is better than other hotels I’ve stayed in the past. If Drury is in the area I’m going to, I’ll book Drury. "
michael 1-night trip
Posted 1 day ago
Drury Inn & Suites Jackson MO

Find out more about Perryville

Search for holiday rentals in Perryville on Expedia! You can easily find your home rentals, villas, holiday apartments in Perryville using one of the methods below:

  • View our selection of featured holiday rentals in Perryville
  • Use the map to find apartments and other holiday homes in the Perryville neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Perryville while they last

Look no further and take a look at our great range of rental properties in Perryville!

Frequently asked questions

Can I find a holiday rental in Perryville?

Yes, there are holiday rentals close to the most popular sights in Perryville, or you can select a more secluded option if you're looking for a relaxing stay. Perryville is known for its wineries and golf courses. Make sure you have time to check out the coffee shops and festivals during your trip.

What are some of the best holiday rentals that Perryville has to offer?

Sunset Ridge - Peaceful 3-bedroom house with WiFi and AC in lovely Weingarten.: This holiday home rental outside of Perryville is located in a rural location, and has a patio, a garden and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family.

How many holiday rentals will I find in Perryville?

With 3 Expedia holiday rentals, you're guaranteed to find just the right place for your Perryville stay.

What’s there to see and do in Perryville?

Mark Twain National Forest and Mississippi River are a couple of lovely local spots to get outside and enjoy nature. While here, National Shrine of Our Lady of the Miraculous Medal and Perryville Country Club are other places worth a visit.

What’s a holiday rental in Perryville like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Perryville. Holiday rentals provide amenities such as WiFi and washers and dryers so you'll feel just like you're at home. If you're concerned about cleanliness, a holiday rental can provide a sense of security away from public hotel lifts and busy concierge desks while still allowing you to travel. You'll also get more space in a holiday rental than in a traditional hotel, which is another reason why a holiday rental is a great option for a family trip.