Poplar Bluff Vacation Homes

A sunset over a calm lake with red autumn leaves on the right.

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Our top choices for Poplar Bluff holiday homes

A spacious living area with a dark grey sofa set, a matching ottoman, and a wooden-paneled wall.

1. 40-Acre Poplar Bluff Nature Lovers Paradise!

Poplar Bluff

Jennie M.

HK$2,376 total

includes taxes & fees

7 Oct - 8 Oct

A house with a front porch decorated with hay bales, a scarecrow, and pumpkins.

2. Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff

Poplar Bluff

Melissa W.

HK$2,230 total

includes taxes & fees

7 Oct - 8 Oct

A wooden deck with steps leading to a house, surrounded by trees.

3. Get Away Acres 1/2 mile off highway 60 extra sanitized

Ellsinore

Anonymous traveller

HK$1,028 total

includes taxes & fees

8 Oct - 9 Oct

A kitchen with wooden cabinets, a stainless steel refrigerator, a stove, and a window.

4. Hunting / Fishing Cabin at Lake Wappapello

Williamsville

HK$1,942 total

includes taxes & fees

4 Nov - 5 Nov

A campfire surrounded by benches in a wooded park area.

5. Brown's Lake House, Family-Friendly 2 Bedroom Retreat Near Lake Wappapello

Wappapello

Shea E.

HK$1,911 total

includes taxes & fees

7 Oct - 8 Oct

A modern kitchen with stainless steel appliances, wooden cabinets, and a white countertop.

6. The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MO

Dexter

HK$1,262 total

includes taxes & fees

19 Oct - 20 Oct

A two-story house with a front porch, a covered entryway, and a small garden with white flowers.

7. Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy

Dexter

Tammy G.

HK$1,685 total

includes taxes & fees

7 Oct - 8 Oct

A modern kitchen with a central island, bar stools, stainless steel appliances, and wooden flooring.

8. The Morning Glory - Country Cottage

Piggott

Justin C.

HK$1,980 total

includes taxes & fees

11 Oct - 12 Oct

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Top Poplar Bluff Hotel Reviews

Hampton Inn Poplar Bluff

10/10 Excellent

"Room was very clean and spacious. Towels were clean, thick and thirsty. Breakfast (included) was good. Bed was comfortable. Hot shower was wonderful. Outdoor walking on and near the property felt safe."

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