Medical Center District

San Antonio

River walk in San Antonio
Riverboat on the San Antonio River Walk, San Antonio, Texas, United States of America.
River walk in San Antonio
SanAntonio_SouthTexasMedicalCenter_6193120_01

Popular places to visit

Things to do


Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd San Antonio TX
The price is HK$627 per night from 6 May to 7 May
HK$627
HK$741 total
6 May - 7 May
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (3,255 reviews)
The only hiccup was the dryer didn't work on the 8th floor and I had to go to the 2nd floor to dry the clothes. The washing machine was broken on the 2nd floor as well.

Reviewed on 8 Apr 2026

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410 San Antonio TX
The price is HK$909 per night from 10 May to 11 May
HK$909
HK$1,081 total
10 May - 11 May
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy a free local area shuttle, room service and a 24-hour fitness centre. Our guests praise the helpful ...
8.6/10 Excellent! (1,020 reviews)
Gym needs radical improvement. Not enough equipment. Cleaning staff did not clean room as thoroughly as one would expect. Sink and surrounding area untouched, and debris left on floor.

Reviewed on 6 Apr 2026

San Antonio Marriott Northwest Medical Center
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

3 out of 5
8585 Marriott Dr San Antonio TX
Fully refundableReserve now, pay when you stay
The price is HK$726 per night from 2 May to 3 May
HK$726
HK$858 total
2 May - 3 May
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,001 reviews)
Clean room.

Reviewed on 7 Apr 2026

Courtyard by Marriott Medical Center San Antonio
Riverwalk Plaza

Riverwalk Plaza

4 out of 5
100 Villita Street San Antonio TX
The price is HK$698 per night from 12 Apr to 13 Apr
HK$698
HK$825 total
12 Apr - 13 Apr
includes taxes & fees
Stay at this family-friendly hotel in San Antonio. Enjoy free Wi-Fi, room service and a 24-hour fitness centre. Our guests praise the restaurant and the helpful ...
8/10 Very Good! (6,411 reviews)
Hotel was quiet. Bed was very comfy. We had a balcony that was nice. View was mostly building but you could see the end of the river walk. The hotel is not in a busy area of the riverwalk. If you want to be in the middle of all the action this is not your hotel. Restaurant was ok if you want something ...

Reviewed on 8 Apr 2026

Riverwalk Plaza
Sonesta ES Suites San Antonio Downtown Alamo Plaza

Sonesta ES Suites San Antonio Downtown Alamo Plaza

3 out of 5
425 Bonham San Antonio TX
The price is HK$793 per night from 6 May to 7 May
HK$793
HK$937 total
6 May - 7 May
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and an outdoor pool. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (2,106 reviews)
Staff was great and hotel was nice and clean. Rooms are perfect with apartment like kitchen .

Reviewed on 8 Apr 2026

Sonesta ES Suites San Antonio Downtown Alamo Plaza
Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk

3 out of 5
105 S Saint Marys Street San Antonio TX
The price is HK$1,065 per night from 9 May to 10 May
HK$1,065
HK$1,259 total
9 May - 10 May
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.4/10 Exceptional! (4,442 reviews)
Clean room, great food, happy hour drinks and food. What a great stay for us and the kids.

Reviewed on 8 Apr 2026

Drury Plaza Hotel San Antonio Riverwalk
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Medical Center District

SanAntonio_UniversityofTexasSanAntonio_502634_03

Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Convocation Center are top sights worth seeing.

Northwest Side
SanAntonio_NorthStarMall_502628_05

Shearer Hills - Ridgeview

While visiting Shearer Hills - Ridgeview, you might make a stop by sights like North Star Mall and San Pedro Driving Range & Par 3 Course.

Shearer Hills - Ridgeview
River Walk in San Antonio, Texas

Midtown

Unique features of Midtown include the river views and bars. Make a stop by San Antonio Zoo and Aquarium or The DoSeum while you're exploring the area.

Midtown
Historic architecture Spanish San Antonio Texas Mission San Jose on a cloudy day

La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

La Cantera District
Tobin Hill

Tobin Hill

Tobin Hill might not have many top sights, but San Antonio Zoo and Aquarium and San Antonio Museum of Art are two attractions nearby that you can check out.

Tobin Hill
Dallas Skyline Reflection on Trinity River During Sunset, Dallas, Texas.

Uptown

If you're spending some time in Uptown, San Antonio Zoo and Aquarium and Marion Koogler McNay Art Museum are top sights worth seeing.

Uptown


Medical Center District

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