A paved pathway lined with tropical plants and palm trees, leading to a gazebo and a fountain.

Search Vacation Homes in Sanibel

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
13 Nov - 15 Nov
In two months
25 Dec - 27 Dec
In three months
22 Jan - 24 Jan
In four months
19 Feb - 21 Feb

Our top choices for Sanibel holiday homes

A spacious living room with a grey sofa, striped armchair, and a woven coffee table. Large windows offer a view of a tropical garden.

1. Driftwood Inn

Driftwood Inn
4.0 star property
Mid Island
10.0 out of 10, Exceptional, (11 reviews)
"Great place to stay on sanibel"
United States
Terri
The price is HK$1,694
HK$3,783 total
includes taxes & fees
28 Oct - 29 Oct
Driftwood Inn
An outdoor seating area with wicker chairs and a central table, surrounded by lush greenery and palm trees.

2. Captain Ed's Cottage at Palmview Inn of Sanibel

Captain Ed's Cottage at Palmview Inn of Sanibel
Mid Island
9.4 out of 10, Exceptional, (28 reviews)
"Clean, quiet and close to the beach."
United States
Frank C.
The price is HK$1,553
HK$3,065 total
includes taxes & fees
28 Oct - 29 Oct
Captain Ed's Cottage at Palmview Inn of Sanibel
A beach with clear turquoise water, a palm tree, and a bright sun.

3. Sandals and Flip Flops, #301

Sandals and Flip Flops, #301
Mid Island
9.0 out of 10, Wonderful, (42 reviews)
"Easy walk to beach. Easy parking. Cheerful decor"
United States
Mark
The price is HK$2,659
HK$4,770 total
includes taxes & fees
31 Oct - 1 Nov
Sandals and Flip Flops, #301
A beach with a single seashell in the foreground and two people in the background.

4. coastal chic cottage "Heron" minutes to the beach! JULY SAVINGS!

coastal chic cottage "Heron" minutes to the beach! JULY SAVINGS!
West End
9.2 out of 10, Wonderful, (44 reviews)
"This was my second stay . It’s so amazing and the location is perfect !!!! We will be back !"
United States
EMILY B.
The price is HK$1,333
HK$3,639 total
includes taxes & fees
2 Nov - 3 Nov
coastal chic cottage "Heron" minutes to the beach! JULY SAVINGS!
An outdoor seating area with wicker chairs and a central table, surrounded by lush greenery and palm trees.

5. Pirates Cove Cottage at Palmview Inn of Sanibel

Pirates Cove Cottage at Palmview Inn of Sanibel
Mid Island
8.8 out of 10, Excellent, (9 reviews)
"We will be back. Close to the beach and such a cute place."
United States
Paula M.
Pirates Cove Cottage at Palmview Inn of Sanibel
An aerial view of a coastal resort with multiple buildings, a beach, and a clear blue sky.

6. Beach Lovers Welcome, #303

Beach Lovers Welcome, #303
Mid Island
9.4 out of 10, Exceptional, (29 reviews)
"Great place and close to the beach!"
United States
Steve W.
The price is HK$2,526
HK$4,630 total
includes taxes & fees
28 Oct - 29 Oct
Beach Lovers Welcome, #303
An outdoor seating area with wicker chairs and a central table, surrounded by lush greenery and palm trees.

7. Palm Retreat Cottage at Palmview Inn of Sanibel

Palm Retreat Cottage at Palmview Inn of Sanibel
Mid Island
9.8 out of 10, Exceptional, (15 reviews)
"Beautiful home, extremely clean, close to everything!"
United States
Nannette C.
Palm Retreat Cottage at Palmview Inn of Sanibel
A sunset over the ocean with waves and a pier in the distance.

8. Kid-friendly beachy house off Sanibel&FM Beach!

Kid-friendly beachy house off Sanibel&FM Beach!
Iona
10.0 out of 10, Exceptional, (9 reviews)
"My daughter and I enjoyed our stay. The house was very clean, beds were comfortable. There were beach chairs and a cooler available to use. The property is not far from the beach and dining, it was easy to find. We would stay here again if our travel plans have us in the area again!"
United States
Jennifer M.
The price is HK$501
HK$1,840 total
includes taxes & fees
2 Nov - 3 Nov
Kid-friendly beachy house off Sanibel&FM Beach!
A modern living room with a dining area, a grey sofa, a coffee table, and a wall clock.

9. Lakeside Oasis Fort Myers

Lakeside Oasis Fort Myers
2.0 star property
Iona
The price is HK$912
HK$1,978 total
includes taxes & fees
2 Nov - 3 Nov
Lakeside Oasis Fort Myers
A sunlit room with a sofa, coffee table, and chairs, large windows with a view of a marina and palm trees.

10. 3-bedroom house in charming Saint James City with Canal Views!

3-bedroom house in charming Saint James City with Canal Views!
Saint James City
10.0 out of 10, Exceptional, (11 reviews)
"Nice place with good fishing in the canal. "
United States
Joshua A.
The price is HK$1,114
HK$3,518 total
includes taxes & fees
28 Oct - 29 Oct
3-bedroom house in charming Saint James City with Canal Views!
A modern kitchen with stainless steel appliances, a dining area with a table and chairs, and a view of the outdoors through a window.

11. Gorgeous relaxing 2BD Near Ft. Myers Beach

Gorgeous relaxing 2BD Near Ft. Myers Beach
Iona
10.0 out of 10, Exceptional, (10 reviews)
"Nice quiet and clean olace to stay"
United States
Henry H.
Gorgeous relaxing 2BD Near Ft. Myers Beach
A covered swimming pool with a clear view of the surrounding area, including a body of water and greenery.

12. Fisherman's Delight With Heated Salt Swimming Pool and a new Boat Lift

Fisherman's Delight With Heated Salt Swimming Pool and a new Boat Lift
St James City
9.6 out of 10, Exceptional, (97 reviews)
"Beautiful home easy access to gulf and awesome cool pool definitely will be back"
United States
Travis W.
The price is HK$1,818
HK$4,211 total
includes taxes & fees
2 Nov - 3 Nov
Fisherman's Delight With Heated Salt Swimming Pool and a new Boat Lift
A spacious living room with a fireplace, a large TV mounted on a stone wall, a modern chandelier, and a kitchen area with a marble countertop.

13. Beach Bliss~Walk to Beach & Times Square~Private Pool

Beach Bliss~Walk to Beach & Times Square~Private Pool
Fort Myers Beach
9.8 out of 10, Exceptional, (24 reviews)
"Perfect location, great long weekend with friends."
United States
Jennifer B.
The price is HK$1,404
HK$3,698 total
includes taxes & fees
2 Nov - 3 Nov
Beach Bliss~Walk to Beach & Times Square~Private Pool
A modern living room with a blue sofa, white coffee table, and a kitchen area in the background.

14. "Relax and Unwind" Peaceful 2-bedroom house in Fort Myers Beach

"Relax and Unwind" Peaceful 2-bedroom house in Fort Myers Beach
Fort Myers Beach
9.8 out of 10, Exceptional, (10 reviews)
"Our hosts were wonderful and the property was clean"
United States
Amy T.
The price is HK$1,067
HK$3,275 total
includes taxes & fees
2 Nov - 3 Nov
"Relax and Unwind" Peaceful 2-bedroom house in Fort Myers Beach
Private kitchen

15. NEW REMODEL Steps from private beach access! 4 BR Family Friendly CLEAN

NEW REMODEL Steps from private beach access! 4 BR Family Friendly CLEAN
Mid Island
9.4 out of 10, Exceptional, (38 reviews)
"Great location! Short easy walk to the beach. House was well equipped with things you would need at the beach. It made our trip so much easier. We felt right at home and loved how close this place was to everything!"
United States
Hester H.
The price is HK$2,424
HK$5,438 total
includes taxes & fees
3 Nov - 4 Nov
NEW REMODEL Steps from private beach access! 4 BR Family Friendly CLEAN
A covered patio area with wicker furniture and a glass table.

16. GOLF COURSE DUPLEX 2 bedroom 1 bath

GOLF COURSE DUPLEX 2 bedroom 1 bath
San Carlos Park
8.8 out of 10, Excellent, (23 reviews)
"A lovely place to stay."
United States
Jennifer D.
The price is HK$902
HK$1,850 total
includes taxes & fees
31 Oct - 1 Nov
GOLF COURSE DUPLEX 2 bedroom 1 bath
An aerial view of a beach with clear turquoise waters, a sandy shoreline, and a small boat anchored near the shore.

17. Bright & Airy 2bed 2bath home near downtown/Weekly and monthly discounts!

Bright & Airy 2bed 2bath home near downtown/Weekly and monthly discounts!
Pelican
9.6 out of 10, Exceptional, (63 reviews)
"House was very clean and looked just like advertised. Had a very comfortable stay and property is close to everything you need. Will definitely come back."
United States
Jennifer B.
The price is HK$690
HK$1,832 total
includes taxes & fees
29 Oct - 30 Oct
Bright & Airy 2bed 2bath home near downtown/Weekly and monthly discounts!
A covered outdoor seating area with wicker furniture, a glass-top table, and a view of a swimming pool and sunset.

18. The Waterfront Fishing Retreat – Luxury • Water Views • Private Dock

The Waterfront Fishing Retreat – Luxury • Water Views • Private Dock
Pelican
9.6 out of 10, Exceptional, (4 reviews)
"Location on VRBO map was inaccurate as it presents with the pool facing west on the opposite side of this eight lake. The home itself was immaculate, the pool however was filthy. I contacted the owner/manager the first morning of my four night stay and it was cleaned the last day of our stay, so that was disappointing."
United States
Sarah S.
The price is HK$960
HK$3,634 total
includes taxes & fees
28 Oct - 29 Oct
The Waterfront Fishing Retreat – Luxury • Water Views • Private Dock
A spacious kitchen with white cabinets, a central island, a ceiling fan, and large windows.

19. Endless Summer Hideaway w/Pool/ocean access/5br

Endless Summer Hideaway w/Pool/ocean access/5br
Pelican
8.8 out of 10, Excellent, (25 reviews)
"Wonderful place to stay"
United States
Becky W.
The price is HK$1,490
HK$3,667 total
includes taxes & fees
2 Nov - 3 Nov
Endless Summer Hideaway w/Pool/ocean access/5br
An indoor swimming pool with a view of the water, lounge chairs, and potted plants.

20. Waterfront Home: Private Pool & Stunning Sea Views

Waterfront Home: Private Pool & Stunning Sea Views
Pelican
10.0 out of 10, Exceptional, (8 reviews)
"Overall, was a wonderful stay and a beautiful home. "
United States
Kyra S.
The price is HK$1,098
HK$3,891 total
includes taxes & fees
17 Nov - 18 Nov
Waterfront Home: Private Pool & Stunning Sea Views
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Sanibel Hotel Reviews

The Anchor Inn

The Anchor Inn

10/10 Excellent
"Room was great. Very clean and the grounds were great!"
Daniel 3-night trip
Posted 15 hours ago
The Anchor Inn

Find out more about Sanibel

Sanibel Vacation Homes information

Number of reviews
405
Accommodation
410 Vacation Homes
Lowest Price
HK$1,832
Highest Price
HK$5,438

Explore a world of travel with Expedia