Santa Ana hotels in Panama City

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Our top choices for Santa Ana hotels

Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana
9.0 out of 10, Wonderful, (93 reviews)
"yes there was laundryroom, iron and nice pool. the stay was very good"
United States
melvin
The price is HK$658
HK$959 total
includes taxes & fees
7 May - 8 May
Casco View Apartments

La Manzana by Wynwood House

La Manzana by Wynwood House
3.0 star property
Santa Ana
7.4 out of 10, Good, (17 reviews)
"Very clean and safe property"
United States
Javier Alberto Lindauer
The price is HK$506
HK$772 total
includes taxes & fees
3 May - 4 May
La Manzana by Wynwood House

Hostal La Cigarra

Hostal La Cigarra
2.0 star property
Santa Ana
7.6 out of 10, Good, (70 reviews)
"Excellent staff, close to metro and embassies. A good location, good room for a great price. I would stay again. "
United Kingdom
Mark
The price is HK$217
HK$241 total
includes taxes & fees
3 May - 4 May
Hostal La Cigarra

Hotel República

Hotel República
2.0 star property
Santa Ana
6.6 out of 10, (190 reviews)
"Good value. "
United States
Matthew
The price is HK$193
HK$215 total
includes taxes & fees
5 May - 6 May
Hotel República

ART CASCO The Hotel

ART CASCO The Hotel
2.0 star property
Santa Ana
6.0 out of 10, (11 reviews)
"Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best"
United States
Eldris
The price is HK$268
HK$297 total
includes taxes & fees
31 May - 1 Jun
ART CASCO The Hotel

Hotel Riazor

Hotel Riazor
3.0 star property
Santa Ana
3.8 out of 10, (11 reviews)
"Rough neighborhood "
Canada
Del
The price is HK$195
HK$216 total
includes taxes & fees
12 May - 13 May
Hotel Riazor

ORHO HOTEL BOUTIQUE PANAMA Airport

ORHO HOTEL BOUTIQUE PANAMA Airport
2.0 star property
20.5 km from Santa Ana
8.8 out of 10, Excellent, (112 reviews)
"Very nice staff Free shuttle Very unique decor and cool room"
United States
Kirk
The price is HK$940
HK$1,221 total
includes taxes & fees
9 May - 10 May
ORHO HOTEL BOUTIQUE PANAMA Airport

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
21.1 km from Santa Ana
8.6 out of 10, Excellent, (2,509 reviews)
"Very friendly staff, good food, clean and close to the airport. A great stay!"
Canada
Norman
The price is HK$995
HK$1,147 total
includes taxes & fees
10 May - 11 May
Crowne Plaza Panama Airport by IHG

Villa Caprichosa

Villa Caprichosa
2.5 star property
18.3 km from Santa Ana
9.8 out of 10, Exceptional, (66 reviews)
"If you find yourself in Tabogo, this is THE place to stay. Arturo and the staff are so great. The hotel is very charming and the food is excellent. There is a room on the top that has its own private pool but it was occupied. Seems like the best room but ours was great and had breakfast right outside door on terrace. "
United States
Jennifer
The price is HK$1,499
HK$1,648 total
includes taxes & fees
3 May - 4 May
Villa Caprichosa

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
19.8 km from Santa Ana
8.4 out of 10, Very good, (1,842 reviews)
"Property was good, would stay there again. "
United States
Juan
The price is HK$952
HK$1,047 total
includes taxes & fees
1 May - 2 May
Riande Aeropuerto Hotel & Casino

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este, 10.2 km from Santa Ana
9.4 out of 10, Exceptional, (279 reviews)
"Very good place to stay and safe place..!"
United States
Somnueg
The price is HK$940
HK$1,396 total
includes taxes & fees
23 May - 24 May
Arcadia Condo Suites

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
14.7 km from Santa Ana
9.0 out of 10, Wonderful, (1,001 reviews)
"Great service, very comfortable beds, truly excellent breakfast manager and staff. "
United States
Elizabeth
The price is HK$854
HK$940 total
includes taxes & fees
23 May - 24 May
Courtyard by Marriott Panama Metromall

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz, 12.7 km from Santa Ana
9.6 out of 10, Exceptional, (690 reviews)
"Breakfast was exceptional, everything you could think of was available. The spa was great and the staff 10/10"
United States
Aeon
The price is HK$2,051
HK$2,256 total
includes taxes & fees
15 May - 16 May
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Westin Panama

The Westin Panama
4.0 star property
Costa del Este, 9.4 km from Santa Ana
9.0 out of 10, Wonderful, (330 reviews)
"Clean room, helpful staff, good breakfast."
United States
Stephanie
The price is HK$1,948
HK$2,143 total
includes taxes & fees
16 May - 17 May
The Westin Panama

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco, 5.7 km from Santa Ana
8.6 out of 10, Excellent, (1,003 reviews)
"The staff greeted us with a warm smile every day. The breakfast was delicious. We would definitely stay here again. "
United States
James
The price is HK$1,168
HK$1,284 total
includes taxes & fees
2 May - 3 May
Sheraton Grand Panama

The Beach House

The Beach House
3.0 star property
Amador, 4.8 km from Santa Ana
8.4 out of 10, Very good, (432 reviews)
"Everting was clean and good nice place to stay "
United States
Kristine
The price is HK$583
HK$641 total
includes taxes & fees
5 May - 6 May
The Beach House

Taboga Palace Spa Hotel

Taboga Palace Spa Hotel
3.5 star property
17.7 km from Santa Ana
9.4 out of 10, Exceptional, (51 reviews)
"My room was perfect just steps from the pool with a great view of the ocean. Dave was a great host and help make my stay truly enjoyable. "
United States
James
The price is HK$1,019
HK$1,121 total
includes taxes & fees
8 May - 9 May
Taboga Palace Spa Hotel

MARINN Tropical Vibes Hotel

MARINN Tropical Vibes Hotel
3.5 star property
Amador, 4.8 km from Santa Ana
8.2 out of 10, Very good, (249 reviews)
"The breakfast was good and lots of parking in a safe place "
United States
Tessa
The price is HK$785
HK$863 total
includes taxes & fees
3 May - 4 May
MARINN Tropical Vibes Hotel

Hotel Bardot Boutique

Hotel Bardot Boutique
3.0 star property
San Felipe, 1.1 km from Santa Ana
9.6 out of 10, Exceptional, (22 reviews)
"Excellent location in the most tourist part of Panama City, Casco Antiguo. Safe area, local to everything, and a beautiful hotel. "
United States
Fatin
The price is HK$830
HK$926 total
includes taxes & fees
3 May - 4 May
Hotel Bardot Boutique

Renaissance Panama City Hotel

Renaissance Panama City Hotel
5.0 star property
Campo Alegre, 3.4 km from Santa Ana
8.6 out of 10, Excellent, (201 reviews)
"It's a very nice hotel and the staff is very nice as well"
United States
Shaied
The price is HK$995
HK$1,095 total
includes taxes & fees
7 May - 8 May
Renaissance Panama City Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Santa Ana

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, pool loungers
Casco View Apartments
3.5 star property
9.0
Wonderful
93 reviews
View
Bar (on property)
Hostal La Cigarra
2.0 star property
7.6
Good
70 reviews
View
View from room
Hotel República
2.0 star property
6.6
190 reviews
View
Front of property
ART CASCO The Hotel
2.0 star property
6.0
11 reviews
View
Bar (on property)
Hotel Riazor
3.0 star property
3.8
11 reviews
View

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

San Felipe

While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.

Top Santa Ana Hotel Reviews

Frequently asked questions

What's it like in Santa Ana?
Santa Ana is a neighbourhood that travellers like for its seafood restaurants, shopping and parks. Are you looking for Santa Ana travel tips? Make sure that you visit Avenida Balboa and El Machetazo Santa Ana while you're in the neighbourhood.
Where is the best hotel for a stay in Santa Ana?
Based on our traveller data, Casco View Apartments is one of the top choices for your stay in Santa Ana. This condo is a short 8-minute walk from Avenida Balboa, and it offers an outdoor pool and in-room kitchens.
How many hotels can I expect to find in Santa Ana?
Expedia has 119 hotels and other accommodation options in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Santa Ana.
What is there to do in this Panama City neighbourhood?
If you're looking forward to a day of shopping in Santa Ana, consider El Machetazo Santa Ana or Avenida Balboa, and pick out the perfect souvenir. When you're sightseeing in Panama City, Albrook Shopping Mall and Avenida Central are also worth a stop.