Santa Ana Holidays

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    Find the right fit

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Top hotels in Santa Ana

Barceló Guatemala City
Barceló Guatemala City
4.5 out of 5
7 Avenida 15-45, Zona 9, Guatemala City, Guatemala
Fully refundableReserve now, pay when you stay
The price is HK$550 per night from 3 Aug to 4 Aug
HK$550
HK$671 total
3 Aug - 4 Aug
includes taxes & fees
9/10 Wonderful! (2,899 reviews)
"Excellent hotel. Rooms are large and clean, location - close to aiport with a shuttle. Staff is super helpful. Food options are very good but overpriced as expected. I loved the heated pool, gym and a hottub."

Reviewed on 5 Jul 2025

Barceló Guatemala City
Hotel Museo Spa Casa Santo Domingo
Hotel Museo Spa Casa Santo Domingo
4.5 out of 5
3a Calle Oriente No 28 A, Antigua Guatemala, Sacatepequez
Fully refundableReserve now, pay when you stay
9.2/10 Wonderful! (1,006 reviews)
"Possibly the most incredible hotel we’ve ever stayed at. Ever."

Reviewed on 4 Jul 2025

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Hotel Museo Spa Casa Santo Domingo
Wyndham Garden Guatemala City
Wyndham Garden Guatemala City
4 out of 5
1a Avenida 12-46 Zona 10, Guatemala City, Guatemala
Fully refundableReserve now, pay when you stay
The price is HK$754 per night from 18 Jul to 19 Jul
HK$754
HK$919 total
18 Jul - 19 Jul
includes taxes & fees
9/10 Wonderful! (1,452 reviews)
"This was my first time saying at Wyndham hotel. I had a great time there, the facility is very clean and close to the airport. The staffs were very pleasant. I will definitely stay there again."

Reviewed on 6 Jul 2025

Wyndham Garden Guatemala City
See all 1,145 properties in Santa Ana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Ana holiday package cost?
You can pick up a holiday package to this destination on Expedia. However, how much your holiday to Santa Ana costs will depend on the season, hotel choice and length of stay.
What are the cheapest months to go to Santa Ana?
If you'd like to snag a cheap Santa Ana holiday package, consider visiting in June, September and October. You'll usually find better prices on accommodation and flights during these months --- perfect for a budget-friendly break.
How many days is enough for Santa Ana?
Generally, a handful of days is enough to tick off the main attractions during your Santa Ana holiday. However, if you'd like to have time to relax or go on day trips, consider extending your itinerary.
How to find the best Santa Ana package deals?
Begin your search for a Santa Ana package deal by entering your destination and preferred trip dates under our "Packages" tab. Then apply some filters, like "Property type" and "Popular locations," to tailor the results to your exact style. You can also sort by "Package discount" and discover offers that come with unbeatable savings. If you don't find the ideal Santa Ana package deal straight away, just play around with your dates and search again. Remember that deals are only available for a limited time, so book early and get your Santa Ana adventure underway.
Is it cheaper to book a Santa Ana holiday as a package?
An Expedia holiday package could land you great savings when compared to arranging hotels and flights individually. Better still, you can customise your Santa Ana trip to fit your exact style. Choose your preferred flight time, select the hotel type and add a car rental. Browse our bundle deals and find out how much you can save.
When to book a holiday package to Santa Ana?
If you're considering a spontaneous Santa Ana trip, check out our last-minute deals that can be booked up to a week before you take off. Don't want to leave things to the last minute? You can score incredible deals on your flights and hotels by booking well in advance.
How to plan a trip to Santa Ana?

  1. Pick your travel dates: What you'd like to do in Santa Ana and your preferred season can help you decide when to travel.
  2. Work out your budget: Make sure you have enough money to cover everything from meals and transportation to flights and activities. Your hotel will probably be the largest expense during your trip to Santa Ana.
  3. Decide how long to go for: Now that you're more familiar with Santa Ana, you can work out the ideal length of your break. Create a rough plan and give yourself enough time to get through everything on your must-do list.
  4. Bundle your accommodation and airfare: After you've nailed down your trip dates and duration, book the perfect Santa Ana holiday package for you.

Popular places to visit

Antigua Guatemala Cathedral

Antigua Guatemala Cathedral

5/5(4 reviews)

You can find out about the history of Antigua Guatemala with a stop at Antigua Guatemala Cathedral. Discover the area's shops or seek out its local tours.

Antigua Guatemala Cathedral
La Merced Church

La Merced Church

5/5(1 review)

Learn about the local history of Antigua Guatemala when you take a trip to La Merced Church. Discover the area's volcano viewpoints and shops.

La Merced Church

Antigua Guatemala Colonial Art Museum

You can study the exhibits at Antigua Guatemala Colonial Art Museum, a museum with a story of its own, during your travels to Antigua Guatemala. Discover the area's volcano viewpoints or seek out its local tours.

Antigua Guatemala Colonial Art Museum

Things to do

Antigua ATV Sunset Tour

Antigua ATV Sunset Tour

HK$510
per adult
100% of travellers recommend
Antigua ATV Sunset Tour
Lake Atitlan One Day Tour from Antigua

Lake Atitlan One Day Tour from Antigua

HK$722
per adult
96% of travellers recommend
Lake Atitlan One Day Tour from Antigua
Tour in Hobbitenango on ATV or UTV

Tour in Hobbitenango on ATV or UTV

HK$589
per adult
100% of travellers recommend
Tour in Hobbitenango on ATV or UTV
See all activities in Antigua Guatemala
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.