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Check prices for these dates

In two weeks
9 Oct - 11 Oct
In two months
20 Nov - 22 Nov
In three months
18 Dec - 20 Dec
In four months
15 Jan - 17 Jan

Our top choices for Santa Isabel holiday homes

A modern dining area with a glass table, white chairs, and a chandelier.

1. Casa Palma Serena - Garden Retreat • Tropical Stay

Casa Palma Serena - Garden Retreat • Tropical Stay
Santa Isabel
10.0 out of 10, Exceptional, (2 reviews)
"Our host was very accommodating! The home was beautiful "
United States
Sally R.
The price is HK$1,224
HK$2,599 total
includes taxes & fees
19 Oct - 20 Oct
Casa Palma Serena - Garden Retreat • Tropical Stay
A view through a window with a view of the sea and a small island.

2. Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep
Santa Isabel
8.8 out of 10, Excellent, (50 reviews)
"Host was very responsive to our texts"
United States
Arnie S.
The price is HK$1,569
HK$2,840 total
includes taxes & fees
23 Sept - 24 Sept
Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep
A modern house with a pool, wooden deck, and outdoor seating area.

3. Coming and enjoy panoramic views to mountains and sea in Santa Isabel

Coming and enjoy panoramic views to mountains and sea in Santa Isabel
Santa Isabel
10.0 out of 10, Exceptional, (1 review)
"This is a unique property with beautiful views. The hosts were incredibly helpful and responsive!"
United States
Annie H.
The price is HK$1,412
HK$2,656 total
includes taxes & fees
23 Sept - 24 Sept
Coming and enjoy panoramic views to mountains and sea in Santa Isabel
A rooftop terrace with a red pool, string lights, and a hanging chair.

4. Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL

Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL
Santa Isabel
10.0 out of 10, Exceptional, (5 reviews)
"Great host communication, central location, lovely home. "
United States
Scott P.
The price is HK$2,001
HK$4,256 total
includes taxes & fees
23 Sept - 24 Sept
Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL
A cozy living room with a wooden ceiling, a sofa, a wicker chair, and a flag on the door.

5. A cozy place to stay walking distance from the beach and Restaurants.

A cozy place to stay walking distance from the beach and Restaurants.
Salinas
9.4 out of 10, Exceptional, (27 reviews)
"Complete kitchen, fairly quiet area, near great restaurants "
United States
John W.
The price is HK$494
HK$1,105 total
includes taxes & fees
24 Sept - 25 Sept
A cozy place to stay walking distance from the beach and Restaurants.
An outdoor patio area with wicker furniture and a stone floor, surrounded by lush greenery and trees.

6. Oasis Salinas

Oasis Salinas
Salinas
8.0 out of 10, Very good, (14 reviews)
"Excellent place to stay near everything in town "
United States
Mayra
The price is HK$745
HK$1,080 total
includes taxes & fees
24 Sept - 25 Sept
Oasis Salinas

7. Enjoyable 2nd story, 3-bedroom house with AC in Coamo, PR

Enjoyable 2nd story, 3-bedroom house with AC in Coamo, PR
Coamo
7.0 out of 10, Good, (2 reviews)
"Spotless cozy , ice cold air"
United States
Alberto
The price is HK$549
HK$1,164 total
includes taxes & fees
25 Sept - 26 Sept
Enjoyable 2nd story, 3-bedroom house with AC in Coamo, PR
A wooden deck with a welcome mat and potted plants.

8. Nostra Casa Vagón

Nostra Casa Vagón
Coamo
10.0 out of 10, Exceptional, (1 review)
"Everything was very clean and organized I got confused with the address and the owner communicated with me and directed me to the exact address when I go to Puerto Rico again I will contact them again to stay at the same place "
United States
Carlos Reyes
The price is HK$549
HK$1,164 total
includes taxes & fees
24 Sept - 25 Sept
Nostra Casa Vagón
A beach with boats docked in calm waters, a clear sky, and a sandy shore.

9. House Salinas (WIFI) - The best part of your getaway

House Salinas (WIFI) - The best part of your getaway
Salinas
9.8 out of 10, Exceptional, (24 reviews)
"Nice cozy home near downtiwn, Salinas PR"
United States
Kenneth C.
The price is HK$1,059
HK$1,859 total
includes taxes & fees
4 Oct - 5 Oct
House Salinas (WIFI) - The best part of your getaway
A wooden dresser with a potted plant on top, a mirror above it, and a decorative piece on the dresser.

10. Trinitarias Guest's House's pool/bar/karaoke/wifi

Trinitarias Guest's House's pool/bar/karaoke/wifi
Salinas
9.0 out of 10, Wonderful, (4 reviews)
"Felt like home beautiful super clean quiet I will definitely be back to this home in our vacations Host is amazing Thank You for sharing this beautiful house with my family "
United States
julio
The price is HK$671
HK$1,378 total
includes taxes & fees
23 Sept - 24 Sept
Trinitarias Guest's House's pool/bar/karaoke/wifi
A stone staircase leading to a white building with a statue in the center, surrounded by lush greenery and metal gates.

11. Casita Azul Boutique Stay in Heart of Barranquitas - Walk Downtown, AC + Balcony

Casita Azul Boutique Stay in Heart of Barranquitas - Walk Downtown, AC + Balcony
Barranquitas
10.0 out of 10, Exceptional, (4 reviews)
"great stay super clean and comfy"
United States
frankie q.
The price is HK$1,020
HK$1,458 total
includes taxes & fees
5 Oct - 6 Oct
Casita Azul Boutique Stay in Heart of Barranquitas - Walk Downtown, AC + Balcony
A hot tub area with a wooden cabin and string lights, surrounded by bamboo.

12. HW Tiny Home Cidra

HW Tiny Home Cidra
Cidra
9.4 out of 10, Exceptional, (3 reviews)
"Beautiful area, great AC, clean hot tub, lovely acces to lake with paddleboat!"
United States
Elizabeth C.
The price is HK$918
HK$1,491 total
includes taxes & fees
23 Sept - 24 Sept
HW Tiny Home Cidra
A poolside view with a tray of food and drinks, a tree, and a mountainous landscape in the background.

13. Campo 5 Retreat W/ Private Climatized Pool

Campo 5 Retreat W/ Private Climatized Pool
Coamo
The price is HK$2,189
HK$3,907 total
includes taxes & fees
23 Sept - 24 Sept
Campo 5 Retreat W/ Private Climatized Pool
A beach scene with the sun setting over the water, palm trees, and a distant shoreline.

14. Family house with Sea View

Family house with Sea View
arroyo
9.0 out of 10, Wonderful, (6 reviews)
"Place was super nice loved the beach view"
United States
Cynthia
Family house with Sea View
A wooden cabin with a sloped roof, surrounded by lush greenery.

15. Romantic Cozy Serene A Frame Mountain Cabin

Romantic Cozy Serene A Frame Mountain Cabin
Cayey
10.0 out of 10, Exceptional, (1 review)
"Will stay again so super cute and romantic"
United States
Kristina
The price is HK$772
HK$1,693 total
includes taxes & fees
23 Sept - 24 Sept
Romantic Cozy Serene A Frame Mountain Cabin
An aerial view of a small island with clear turquoise waters, a sandy beach, and a few structures.

16. Expansive Paradise with Private Jacuzzi and Tropical Patio

Expansive Paradise with Private Jacuzzi and Tropical Patio
Ponce
8.8 out of 10, Excellent, (3 reviews)
"Hella chill"
United States
Sammy S.
The price is HK$1,200
HK$2,850 total
includes taxes & fees
23 Sept - 24 Sept
Expansive Paradise with Private Jacuzzi and Tropical Patio
A rustic outdoor seating area with a view of a lake, a woven basket, and a wooden bench.

17. Grandpa's lake house lake private access mountain view museum 1950's experience

Grandpa's lake house lake private access mountain view museum 1950's experience
Cidra
9.4 out of 10, Exceptional, (6 reviews)
"We had a great peaceful visit!"
United States
Kelly N.
The price is HK$532
HK$726 total
includes taxes & fees
23 Sept - 24 Sept
Grandpa's lake house lake private access mountain view museum 1950's experience
A view of a lush landscape with a body of water, palm trees, and a building with a red roof.

18. LA CASITA DEL LAGO

LA CASITA DEL LAGO
Cidra
10.0 out of 10, Exceptional, (5 reviews)
"The location was amazing "
United States
Maria
The price is HK$893
HK$1,690 total
includes taxes & fees
25 Sept - 26 Sept
LA CASITA DEL LAGO

19. Spacious Retreat with Private Jacuzzi and Tropical Patio

Spacious Retreat with Private Jacuzzi and Tropical Patio
Ponce
9.0 out of 10, Wonderful, (4 reviews)
"This property was convenient, super clean and had everything that we needed! "
United States
Heather L.
The price is HK$1,066
HK$2,174 total
includes taxes & fees
23 Sept - 24 Sept
Spacious Retreat with Private Jacuzzi and Tropical Patio
A wooden deck with a bench, a doormat, and a view of a lush landscape.

20. Cozy cabin with hot water jacuzzi and AC in the mountains of Guayama.

Cozy cabin with hot water jacuzzi and AC in the mountains of Guayama.
Guayama
10.0 out of 10, Exceptional, (2 reviews)
"Property was so beautiful didn’t have any complains. Everything you need in one spot you’d never want to leave."
United States
Jonathan
The price is HK$902
HK$1,458 total
includes taxes & fees
6 Oct - 7 Oct
Cozy cabin with hot water jacuzzi and AC in the mountains of Guayama.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Isabel Hotel Reviews

Aloft by Marriott Ponce Hotel & Casino

Aloft by Marriott Ponce Hotel & Casino

10/10 Excellent
"Hotel muy limpio Comida en restaurante muy buena"
Sandra 2-night trip
Posted 5 hours ago
Aloft by Marriott Ponce Hotel & Casino

Find out more about Santa Isabel

Santa Isabel Vacation Homes information

Number of reviews
121
Accommodation
104 Vacation Homes
Lowest Price
HK$726
Highest Price
HK$4,256