South Main hotels in Houston from HK$559

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Top 10 Trending Hotels Near South Main, Houston from HK$559

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Comfort Suites Houston near Medical Center- NRG Stadium

Comfort Suites Houston near Medical Center- NRG Stadium

2.5 star property
South Main
8.6 out of 10, Excellent, (1002)
"Was a great stay and rigjt next to the stadium all around recomended"
United States
Jason
The price is HK$701
HK$820 total
includes taxes & fees
30 Nov - 1 Dec
Comfort Suites Houston near Medical Center- NRG Stadium
Lobby
Wyndham Houston near NRG Park/Medical Center

Wyndham Houston near NRG Park/Medical Center

3.5 star property
South Main
7.2 out of 10, Good, (1191)
"Perfect "
United States
Maria
The price is HK$1,012
HK$1,184 total
includes taxes & fees
1 Dec - 2 Dec
Wyndham Houston near NRG Park/Medical Center
Gazebo
Wingate Houston near NRG Park/Medical Center

Wingate Houston near NRG Park/Medical Center

3.0 star property
South Main
6.6 out of 10, (971)
"Great staff, excellent service and convenient to the area we were wanting to be. Room was clean and bed was very comfortable."
United States
Roy
The price is HK$1,004
HK$1,175 total
includes taxes & fees
1 Dec - 2 Dec
Wingate Houston near NRG Park/Medical Center
1 bedroom, hypo-allergenic bedding, in-room safe, individually decorated
Quality Inn & Suites NRG Park - Medical Center

Quality Inn & Suites NRG Park - Medical Center

2.5 star property
South Main
6.4 out of 10, (1000)
"Everything was great"
United States
Yeimi
The price is HK$478
HK$559 total
includes taxes & fees
22 Dec - 23 Dec
Quality Inn & Suites NRG Park - Medical Center
Exterior
Candlewood Suites Houston Medical Center by IHG

Candlewood Suites Houston Medical Center by IHG

2.5 star property
South Main
7.4 out of 10, Good, (816)
"Yes the where"
United States
Robert
The price is HK$523
HK$612 total
includes taxes & fees
28 Nov - 29 Nov
Candlewood Suites Houston Medical Center by IHG
Lobby
Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center

3.0 star property
Texas Medical Center, 3.1 km from South Main
9.2 out of 10, Wonderful, (2136)
"Great stay"
United States
Vallie
The price is HK$899
HK$1,057 total
includes taxes & fees
1 Dec - 2 Dec
Hyatt Place Houston Medical Center
50-inch Smart TV with cable channels, TV, Netflix
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4.0 star property
Texas Medical Center, 3.5 km from South Main
9.0 out of 10, Wonderful, (3575)
"Great property, beautiful room, great staff!"
United States
Lindsay
The price is HK$1,026
HK$1,200 total
includes taxes & fees
21 Dec - 22 Dec
Blossom Hotel Houston, Curio Collection by Hilton
City view from property
The Whitehall Houston

The Whitehall Houston

4.0 star property
Houston Central Business District, 10 km from South Main
8.6 out of 10, Excellent, (1873)
"Great stay."
United States
Anita
The price is HK$921
HK$1,077 total
includes taxes & fees
26 Nov - 27 Nov
The Whitehall Houston
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Hyatt House Houston Medical Center

Hyatt House Houston Medical Center

3.0 star property
Texas Medical Center, 3.1 km from South Main
9.2 out of 10, Wonderful, (1168)
"I had a great stay! I travel to Houston several times a year and this is one of my favorite places to stay."
United States
Star
The price is HK$899
HK$1,057 total
includes taxes & fees
1 Dec - 2 Dec
Hyatt House Houston Medical Center
Exterior detail
DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4.0 star property
8.9 km from South Main
8.2 out of 10, Very good, (2937)
"Great location nice beds staff was amazing and good breakfast "
United States
Canyelle
The price is HK$863
HK$1,017 total
includes taxes & fees
20 Dec - 21 Dec
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Exterior
The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria

4.0 star property
The Galleria, 8.8 km from South Main
8.4 out of 10, Very good, (1388)
"Great place to stay!"
United States
Curtis
The price is HK$926
HK$1,084 total
includes taxes & fees
24 Nov - 25 Nov
The Royal Sonesta Houston Galleria
Terrace/patio
Hilton Garden Inn Houston Medical Center, TX

Hilton Garden Inn Houston Medical Center, TX

3.0 star property
Texas Medical Center, 4.7 km from South Main
9.4 out of 10, Exceptional, (1006)
"Clean room and nice staff"
Canada
Guillermo
The price is HK$804
HK$940 total
includes taxes & fees
30 Nov - 1 Dec
Hilton Garden Inn Houston Medical Center, TX
Sun deck
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 star property
4.4 km from South Main
8.4 out of 10, Very good, (1678)
"Clean rooms, comfortable bed, & friendly staff"
United States
Thomas
The price is HK$540
HK$640 total
includes taxes & fees
25 Nov - 26 Nov
Hilton Houston Plaza/Medical Center
Breakfast, lunch, brunch served; American cuisine, garden views
Hyatt Regency Houston West

Hyatt Regency Houston West

3.5 star property
23.2 km from South Main
8.6 out of 10, Excellent, (1232)
"Great room and staff."
United States
Brad
The price is HK$835
HK$977 total
includes taxes & fees
23 Nov - 24 Nov
Hyatt Regency Houston West
Exterior
Holiday Inn Express & Suites Houston - Memorial City Centre by IHG

Holiday Inn Express & Suites Houston - Memorial City Centre by IHG

2.5 star property
Memorial City, 18.4 km from South Main
8.8 out of 10, Excellent, (1007)
"Clean, friendly staff, good breakfast, and all around great stay! "
United States
Rebecca
The price is HK$741
HK$871 total
includes taxes & fees
14 Dec - 15 Dec
Holiday Inn Express & Suites Houston - Memorial City Centre by IHG
Reception
InterContinental Houston by IHG

InterContinental Houston by IHG

4.0 star property
Texas Medical Center, 4.1 km from South Main
9.2 out of 10, Wonderful, (1002)
"Clean room, excellent staff, kind and respectful."
United States
DIANA
The price is HK$888
HK$1,195 total
includes taxes & fees
28 Nov - 29 Nov
InterContinental Houston by IHG
Premium bedding, desk, iron/ironing board, free WiFi
Haven Inn & Suites Downtown Houston

Haven Inn & Suites Downtown Houston

2.5 star property
North Houston, 18.8 km from South Main
9.4 out of 10, Exceptional, (1001)
"Very clean and safe, would stay again"
United States
Krimson
Haven Inn & Suites Downtown Houston
Lobby
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4.0 star property
Houston Central Business District, 10.9 km from South Main
8.4 out of 10, Very good, (3899)
"Hotel was beautiful, room was great for the price"
United States
Sonya
The price is HK$626
HK$733 total
includes taxes & fees
27 Nov - 28 Nov
Club Quarters Hotel Downtown, Houston
View from room
Home2 Suites by Hilton at the Galleria

Home2 Suites by Hilton at the Galleria

3.0 star property
Greater Uptown, 8 km from South Main
8.8 out of 10, Excellent, (965)
" Clean room , comfortable Good breakfast "
United States
Yelyzaveta
The price is HK$823
HK$963 total
includes taxes & fees
1 Dec - 2 Dec
Home2 Suites by Hilton at the Galleria
Terrace/patio
Holiday Inn Express Houston - Galleria Area by IHG

Holiday Inn Express Houston - Galleria Area by IHG

2.5 star property
The Galleria, 8.6 km from South Main
9.4 out of 10, Exceptional, (1008)
"This Holiday Inn Express was one of the nicest with the friendliest staff and best breakfast I have experienced in a long time travelling!"
United States
Melissa
The price is HK$834
HK$976 total
includes taxes & fees
29 Nov - 30 Nov
Holiday Inn Express Houston - Galleria Area by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in South Main

Find the best South Main areas for the activities you enjoy most.
Discovery Green showing modern architecture, a city and a high-rise building

Downtown Houston

Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers.

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

Texas Medical Center

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

Menil Collection which includes interior views and art

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Menil Collection or Houston Center for Photography while you're exploring the area.

Northside

While you're in Northside, take in top sights like The Heights Theater or Greenspoint Mall, and hop on the metro to see more of the city at Northline Transit Center/HCC Station or Melbourne/North Lindale Station.

Top South Main Hotel Reviews

Hilton Americas-Houston

Hilton Americas-Houston

10/10 Excellent
"Beautiful hotel"
Shannon 2-night trip
Posted 7 hours ago
Hilton Americas-Houston

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Frequently asked questions

What is South Main like?
You'll be sure to have fun exploring Houston's South Main neighbourhood. Consider a visit to NRG Park as part of your South Main travel plans.
Where is the best hotel for a stay in South Main?
Based on Expedia customer reviews, Comfort Suites Houston near Medical Center- NRG Stadium is the highest ranked property in South Main. This hotel is a short 10-minute walk from NRG Stadium, and it offers free breakfast and a fitness centre. Other top choices in the neighbourhood include Candlewood Suites Houston Medical Center by IHG and Quality Inn & Suites NRG Park - Medical Center.
How many hotels should I expect to find in South Main?
If you're searching for places to stay in Houston, Expedia has something to meet your needs with 64 South Main hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in South Main, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best options available in South Main.
What can I see and do in this Houston neighbourhood?
NRG Park is an attraction you might want to check out while you're in South Main. While you're out sightseeing in Houston, make sure that you visit other sights such as NRG Stadium or NRG Arena.
How can I get around South Main and the greater Houston area?
Ready to get out and explore the city? Fannin South Station is the closest metro station.