A paved courtyard with a brick pathway, trees, and a distant view of a road and buildings.

Search Vacation Homes in Southeast Iowa

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Our top choices for Southeast Iowa holiday homes

1. Private Woodsy Cabin close to River and Keosauqua

Private Woodsy Cabin close to River and Keosauqua
Keosauqua
9.8 out of 10, Exceptional, (20 reviews)
"Perfect location !! Lovely place and I can't say enough about how much we loved their turkey!"
United States
Julie
The price is HK$952
HK$1,620 total
includes taxes & fees
30 Aug - 31 Aug
Private Woodsy Cabin close to River and Keosauqua

2. Charming One Bedroom home in Keosauqua near shops

Charming One Bedroom home in Keosauqua near shops
Keosauqua
9.2 out of 10, Wonderful, (15 reviews)
"Quiet, clean and comfortable. Nicely appointed. We saw a deer and a turkey when we stepped out of the house Sunday morning. Good communications. "
United States
Melinda L.
The price is HK$649
HK$1,254 total
includes taxes & fees
10 Sept - 11 Sept
Charming One Bedroom home in Keosauqua near shops

3. Nauvoo Windmill Farmhouse 10-12 people

Nauvoo Windmill Farmhouse 10-12 people
Niota
10.0 out of 10, Exceptional, (19 reviews)
"Great stay very peaceful "
United States
larry r.
The price is HK$980
HK$1,761 total
includes taxes & fees
7 Sept - 8 Sept
Nauvoo Windmill Farmhouse 10-12 people

4. Grand Victorian on the Mississippi

Grand Victorian on the Mississippi
Fort Madison
9.8 out of 10, Exceptional, (32 reviews)
"The home was beautifully decorated! We enjoyed our stay."
United States
Theresa G.
The price is HK$1,521
HK$3,433 total
includes taxes & fees
23 Sept - 24 Sept
Grand Victorian on the Mississippi

5. PAGEANT -Eagles Nest home with view of the Mississippi and Gorgeous Sunsets

PAGEANT -Eagles Nest home with view of the Mississippi and Gorgeous Sunsets
Nauvoo
9.2 out of 10, Wonderful, (9 reviews)
"Beautiful home with an amazing view of the Mississippi River. So peaceful to sit and watch the water, boats, birds, etc. Lots to do in the area, places to eat, etc. Will definitely keep in mind again for a peaceful weekend getaway."
United States
Sonia M.
The price is HK$1,129
HK$2,500 total
includes taxes & fees
5 Sept - 6 Sept
PAGEANT -Eagles Nest home with view of the Mississippi and Gorgeous Sunsets

6. Experience Beautiful Pioneer Home In Nauvoo!

Experience Beautiful Pioneer Home In Nauvoo!
Nauvoo
9.8 out of 10, Exceptional, (87 reviews)
"We had a great stay!"
United States
Darin B.
The price is HK$1,489
HK$2,966 total
includes taxes & fees
27 Sept - 28 Sept
Experience Beautiful Pioneer Home In Nauvoo!

7. Riverside Waterfront on the Mississippi River

Riverside Waterfront on the Mississippi River
Pontoosuc
9.6 out of 10, Exceptional, (24 reviews)
"Great place good location "
United States
willmer m.
The price is HK$1,164
HK$2,297 total
includes taxes & fees
26 Sept - 27 Sept
Riverside Waterfront on the Mississippi River

8. Woodland Retreat High Above the Mississippi River

Woodland Retreat High Above the Mississippi River
Hamilton
9.0 out of 10, Wonderful, (2 reviews)
"I loved this little space. It was an old Lil cottage that gave me peace and comfort. We were up there for a funeral. But the cottage made us not want to leave for the real world. my two sons one and adult and one a teen also loved it! The host was very helpful! I will be back...well maybe for vacation next time!"
United States
Roberta
The price is HK$1,164
HK$2,031 total
includes taxes & fees
29 Aug - 30 Aug
Woodland Retreat High Above the Mississippi River

9. Historic 1840s Lamoreaux House / Modern Addition

Historic 1840s Lamoreaux House / Modern Addition
Nauvoo
9.6 out of 10, Exceptional, (25 reviews)
"Plenty of space for our family. Good location."
United States
Chelsea S.
The price is HK$1,940
HK$2,829 total
includes taxes & fees
5 Sept - 6 Sept
Historic 1840s Lamoreaux House / Modern Addition

10. The Little Red House

The Little Red House
Fairfield
9.6 out of 10, Exceptional, (10 reviews)
"Beautiful house and very clean!!!"
United States
Kelli J.
The price is HK$768
HK$1,659 total
includes taxes & fees
30 Aug - 31 Aug
The Little Red House

11. Charming Family Retreat - 15 min to Nauvoo & Carthage

Charming Family Retreat - 15 min to Nauvoo & Carthage
Hamilton
10.0 out of 10, Exceptional, (31 reviews)
"Love this place we have stayed several times"
United States
Tara J.
The price is HK$741
HK$1,466 total
includes taxes & fees
4 Sept - 5 Sept
Charming Family Retreat - 15 min to Nauvoo & Carthage

12. Riverview Orchard 2: Master Suite Studio Style

Riverview Orchard 2: Master Suite Studio Style
Hamilton
9.4 out of 10, Exceptional, (6 reviews)
"Very clean, great view, great place! Highly recommend!"
United States
Addison M.
The price is HK$745
HK$1,346 total
includes taxes & fees
14 Sept - 15 Sept
Riverview Orchard 2: Master Suite Studio Style

13. Family friendly 3 bedroom home in Kahoka MO

Family friendly 3 bedroom home in Kahoka MO
Kahoka
9.2 out of 10, Wonderful, (12 reviews)
"Absolutely friendly and welcoming hosts. "
United States
Jay M.
The price is HK$1,254
HK$1,850 total
includes taxes & fees
28 Sept - 29 Sept
Family friendly 3 bedroom home in Kahoka MO

14. Cozy House

Cozy House
Biggsville
10.0 out of 10, Exceptional, (8 reviews)
"Great place for our needs!"
United States
jdl j.
The price is HK$670
HK$1,383 total
includes taxes & fees
31 Aug - 1 Sept
Cozy House

15. Family Home in Carthage

Family Home in Carthage
Carthage
10.0 out of 10, Exceptional, (18 reviews)
"Super cute little home. Beds were comfy"
United States
Jesse
The price is HK$763
HK$1,498 total
includes taxes & fees
2 Sept - 3 Sept
Family Home in Carthage

16. Home Away From Home

Home Away From Home
Biggsville
10.0 out of 10, Exceptional, (3 reviews)
"Our stay was exceptional, couldn't have asked for a better home for out 4 day stay. Everything was so clean and roomy. Great kitchen area and 2 living rooms with a very nice TV 📺. I will be rebooking again in the future. The host was most helpful and kind."
United States
Kathy
The price is HK$800
HK$1,570 total
includes taxes & fees
22 Sept - 23 Sept
Home Away From Home

17. Idyllic Biggsville Vacation Rental: 10 Mi to River

Idyllic Biggsville Vacation Rental: 10 Mi to River
Biggsville
10.0 out of 10, Exceptional, (3 reviews)
"We enjoyed our peaceful stay in this clean, beautiful vacation rental. Perfect for a weekend getaway. "
United States
Lisa S.
The price is HK$862
HK$1,570 total
includes taxes & fees
28 Sept - 29 Sept
Idyllic Biggsville Vacation Rental: 10 Mi to River

18. Golf and Stay house is next to Twin Oaks Golf Course. Lovely 9 hole golf course.

Golf and Stay house is next to Twin Oaks Golf Course. Lovely 9 hole golf course.
Blandinsville
9.4 out of 10, Exceptional, (17 reviews)
"We loved how clean the house was. It was good for staying at for commencement at WIU. Mattresses were comfortable. Shower was nice. Very nice place to stay."
United States
Annie
The price is HK$854
HK$1,279 total
includes taxes & fees
1 Sept - 2 Sept
Golf and Stay house is next to Twin Oaks Golf Course. Lovely 9 hole golf course.

19. If you want quiet, peaceful, & a beautiful sunset, you’ll love House on the Hill

If you want quiet, peaceful, & a beautiful sunset, you’ll love House on the Hill
Media
10.0 out of 10, Exceptional, (1 review)
"The photos did not do justice to how nice everything was, the covered sitting area outside was perfect for a sunrise coffee. We only stayed for one night and left early. Comfortable and quiet!"
United States
Joe B.
The price is HK$706
HK$1,163 total
includes taxes & fees
29 Aug - 30 Aug
If you want quiet, peaceful, & a beautiful sunset, you’ll love House on the Hill

20. Oquawka Cottage With River View

Oquawka Cottage With River View
Oquawka
9.6 out of 10, Exceptional, (9 reviews)
"Cute little cottage, very clean. Wonderful beds. Very peaceful visit. Will come again"
United States
sally
The price is HK$734
HK$1,509 total
includes taxes & fees
30 Aug - 31 Aug
Oquawka Cottage With River View
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Southeast Iowa Hotel Reviews

Find out more about Southeast Iowa

Southeast Iowa Vacation Homes information

Number of reviews
223
Accommodation
58 Vacation Homes
Lowest Price
HK$1,163
Highest Price
HK$3,433

Explore a world of travel with Expedia