Southeast Missouri
Travel Guide
Visit Southeast Missouri
Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
The price is HK$780 per night from 1 Feb to 2 Feb
HK$780
HK$880 total
1 Feb - 2 Feb
includes taxes & fees
Stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,005 reviews)
This place feels like customer service from 1950. The service was outstanding
Reviewed on 23 Jan 2026
The Riverview
777 Main St Cape Girardeau MO
The price is HK$721 per night from 12 Feb to 13 Feb
HK$721
HK$814 total
12 Feb - 13 Feb
includes taxes & fees
Stay at this business-friendly hotel in Cape Girardeau. Enjoy free Wi-Fi, free parking and 2 restaurants. Popular attractions Isle Casino Cape Girardeau and ...
9.2/10 Wonderful! (494 reviews)
Room was clean and staff were all nice. Overall it was a good experience. My only complaint is how small the shower was. I would assume not all of the rooms have that small of a shower.
Reviewed on 26 Jan 2026
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
The price is HK$418 per night from 6 Feb to 7 Feb
HK$418
HK$476 total
6 Feb - 7 Feb
includes taxes & fees
Stay at this business-friendly hotel in Farmington. Enjoy free breakfast, free parking and an outdoor pool. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (1,007 reviews)
Clean room and nice staff
Reviewed on 25 Jan 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
7555 State Hwy Y French Village MO
Stay at this cabin in French Village. Enjoy free parking, patios and climate control.
9.8/10 Exceptional! (48 reviews)
I had a great time with my mom there!
Reviewed on 5 Jan 2026
Johnson's Shut-ins State Park
148 Taum Sauk Trail Middle Brook MO
Stay at this cabin in Middle Brook. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Popular attractions Johnson's Shut-ins State Park and Taum Sauk ...
10/10 Exceptional! (1 review)
These newer cabins are clean and have everything you need. Highly recommend!
Reviewed on 5 Nov 2025
Little Blue Cottage on Spanish
Cape Girardeau MO
Stay at this holiday home in Cape Girardeau. Popular attractions eDen Spa & Salon and The Glenn House are located nearby.
8.4/10 Very Good! (48 reviews)
The amenities were in pretty strange conditions. Not non functional. Just strange. Fairly priced. I would stay again
Reviewed on 30 Oct 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check Southeast Missouri hotel availability
Popular places to visit
Southeast Missouri State University
Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.
Elephant Rocks State Park
You can take time to visit Elephant Rocks State Park during your travels to Ironton. While you're in the area, wander around the parks.
Lake Wappapello
Commune with nature and explore the great outdoors at Lake Wappapello during your travels in Wappapello. While in this family-friendly area, you can enjoy the restaurants.
Current River State Park
Commune with nature and explore the great outdoors at Current River State Park during your travels in Salem. While you're in the area, stroll along the riverfront.
Hawn State Park
You can take time to visit Hawn State Park during your travels to Ste Genevieve. Discover the area's cafes or seek out the golf courses.
Isle Casino Cape Girardeau
Why not roll the dice with a visit to Isle Casino Cape Girardeau during your time in Cape Girardeau? While in this family-friendly area, you can savour the top-notch restaurants.
Explore a world of travel with Expedia
- Spa Hotel Hotels in Southeast Missouri
- Cheap Hotels in Poplar Bluff
- Cabin Rentals in Annapolis
- Black Hotels
- Hotels near Powder Mill Cave Natural Area
- Historic Hotel Hotels in Southeast Missouri
- Romantic Hotel Hotels in Southeast Missouri
- Motels in Fredericktown
- Independent Hotels in Qulin
- B&B in Middle Brook
- Pet-Friendly Hotel Hotels in Farmington
- Apartments in Ste Genevieve
- 3 Star Hotels in Park Hills
- Cottages in New Offenburg
- Spa Hotel Hotels in De Soto
- Business Hotel Hotels in Farmington
- Dexter Hotels
- Cabin Rentals in Cadet
- 4 Star Hotels in Potosi
- Annapolis Hotels
- Hotels near eDen Spa & Salon
- Hotels near Echo Bluff State Park
- Hotels near Elephant Rocks State Park
- Cabin Rentals in Sikeston
- Poplar Bluff Hotels
- Hotel with Pool Hotels in Bonne Terre
- Qulin Hotels
- Desloge Hotels
- Pet-Friendly Hotel Hotels in Dexter
- Apartments in Eminence
- 4 Star Hotels in Cadet
- 3 Star Hotels in Valles Mines
- Fredericktown Hotels
- Hotels near Trail of Tears State Park
- Vacation Homes in Qulin
- Valles Mines Hotels
- Drury Inn & Suites Hotels in Sikeston
- Cabin Rentals in Doniphan
- Cabin Rentals in Poplar Bluff
- Oran Hotels
- 5 Star Hotels in Leadwood
- Pet-Friendly Hotel Hotels in Poplar Bluff
- Park Hills Hotels
- Winery Hotel Hotels in Ste Genevieve
- Farmington Hotels
- Hotels near National Shrine of Our Lady of the Miraculous Medal
- Scott County Hotels
- Hotels near Johnson's Shut-ins State Park
- Hotels near Silver Mine Recreation Area
- Cabin Rentals in St Mary
- Cheap Hotels in Sikeston
- Apartments in Arcadia
- Apartments in Farmington
- Tiff Hotels
- Lodges in Eminence
- Cabin Rentals in Qulin
- 5 Star Hotels in Oran
- Bar Hotel Hotels in Ste Genevieve
- Bunker Hotels
- Hotels near Hawn State Park
- Marble Hill Hotels
- Cabin Rentals in Wappapello
- Hilton Hotels in New Offenburg
- Motels in Ellington
- 4 Star Hotels in Oran
- Hotels near Felix Valle House State Historic Site
- Motels in Oran
- Hotels near Current River State Park
- Hotels near St. Francois State Park
- La Quinta Inn & Suites Hotels in Farmington
- Bar Hotel Hotels in Poplar Bluff
- Hotels near Dillard Mill State Historic Site
- Doniphan Hotels
- Hotels near K Bridge Recreation Area
- Hotels near Taum Sauk Mountain State Park
- Cabin Rentals in Van Buren
- Hotels near Missouri Mines State Historic Site
- B&B in Black
