A modern building with a unique triangular roof and a central spire.

Santa Lucia hotels in Syracuse

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Check prices for these dates

This weekend
25 Sept - 27 Sept
Next weekend
2 Oct - 4 Oct

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Our top choices for Santa Lucia hotels

A rooftop terrace with lounge chairs, a hot tub, and a view of palm trees and buildings.

1. Caportigia Boutique Hotel

Caportigia Boutique Hotel
5.0 star property
Santa Lucia
9.4 out of 10, Exceptional, (296 reviews)
"Lovely hotel in a great spot, very helpful staff."
Australia
Mandy
The price is HK$1,614
HK$1,865 total
includes taxes & fees
24 Oct - 25 Oct
Caportigia Boutique Hotel
A woman in a black swimsuit sitting in a hot tub overlooking a beach with a clear sky and the sun shining.

2. Re Dionisio Luxury Suites

Re Dionisio Luxury Suites
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (58 reviews)
"Wonderful property, excellent staff and the most amazing view from the apartment"
Australia
Anthony
The price is HK$2,154
HK$2,458 total
includes taxes & fees
4 Oct - 5 Oct
Re Dionisio Luxury Suites
A modern hotel room with a flat-screen TV mounted on a dark wall, a white desk with a remote control, a bed with a black and white patterned bedspread, and a window with curtains.

3. Nostos rooms & Apartments

Nostos rooms & Apartments
3.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (290 reviews)
"A really nice room, the bed was extremely comfortable and the staff were very friendly."
United Kingdom
Michael
The price is HK$665
HK$758 total
includes taxes & fees
21 Oct - 22 Oct
Nostos rooms & Apartments
A historic building with ornate balconies, a grand entrance, and flags of the European Union and Italy.

4. Grande Albergo Alfeo

Grande Albergo Alfeo
4.0 star property
Santa Lucia
8.6 out of 10, Excellent, (699 reviews)
"The hotel is very nice and the staff were very helpful. It’s very close to the main attractions and restaurants. Breakfast was very good and nice view in the rooftop."
Canada
Bernie
The price is HK$993
HK$1,132 total
includes taxes & fees
2 Oct - 3 Oct
Grande Albergo Alfeo
A neatly made bed with a dark quilt, white pillows, and a beige headboard. There are two bedside lamps on either side of the bed.

5. Melody rooms

Melody rooms
Santa Lucia
10.0 out of 10, Exceptional, (1 review)
The price is HK$311
HK$354 total
includes taxes & fees
29 Sept - 30 Sept
Melody rooms
A room with a table and chairs, a view of a harbor with boats and buildings, and a clear sky.

6. Lakkios

Lakkios
3.0 star property
Santa Lucia
9.2 out of 10, Wonderful, (76 reviews)
"The location of this place is amazing and that balcony view iconic. Staff super helpful too."
Canada
Marsel
The price is HK$809
HK$922 total
includes taxes & fees
22 Oct - 23 Oct
Lakkios
A hotel room with a large bed, a chair, a small table, and a chandelier.

7. Hotel Palazzo Cavalieri

Hotel Palazzo Cavalieri
4.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (44 reviews)
"Good central location & nice breakfast selection "
Australia
Alan
The price is HK$1,060
HK$1,208 total
includes taxes & fees
21 Oct - 22 Oct
Hotel Palazzo Cavalieri
A balcony with wicker chairs and a glass table overlooking a marina with boats.

8. Fortaleza Charme House

Fortaleza Charme House
Santa Lucia
10.0 out of 10, Exceptional, (41 reviews)
"Beautiful accomodation, perfect location close to restauranys and attractions, clean room/all renovated with style, friendly personnel, nice view of the port"
Canada
Martine
The price is HK$1,596
HK$1,820 total
includes taxes & fees
20 Oct - 21 Oct
Fortaleza Charme House
A terrace with white tables and chairs, white umbrellas, and a view of the sea.

9. Giuggiulena Villa

Giuggiulena Villa
3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (132 reviews)
"We had an amazing time. Sabrina and Claudia were wonderful. The place is top notch in everything they do. The food was so fresh and delicious . I was sad when i had to leave them. High praise for this hotel. The views breath taking."
United States
Duane
The price is HK$1,651
HK$1,905 total
includes taxes & fees
16 Oct - 17 Oct
Giuggiulena Villa
A balcony with potted plants and a metal railing.

10. Piccolo Hotel Casa Mia

Piccolo Hotel Casa Mia
3.0 star property
Santa Lucia
8.6 out of 10, Excellent, (387 reviews)
"Fantastic breakfast, great cakes and good coffee. The rooms were comfortable and the location is great for all the important places to be in Siracusa. It was quiet and peaceful and the staff were helpful and friendly."
United Kingdom
Richard
The price is HK$431
HK$491 total
includes taxes & fees
18 Oct - 19 Oct
Piccolo Hotel Casa Mia
An open balcony with a table and chairs, potted plants, and a view of a building with balconies and windows.

11. Calafatari B&B

Calafatari B&B
3.0 star property
Santa Lucia
9.8 out of 10, Exceptional, (18 reviews)
"Clean, very convenient for exploring Ortigia. Nice continental breakfast."
United States
Mary
The price is HK$1,173
HK$1,337 total
includes taxes & fees
6 Oct - 7 Oct
Calafatari B&B
A hot tub with a view of a marina.

12. Casa Miranda Boutique

Casa Miranda Boutique
Santa Lucia
8.0 out of 10, Very good, (2 reviews)
"Great hotel. Close to everything 15min walk into Ortigia and the excursions dock. The staff are incredibly helpful and thoughtful. Rooms are clean and nice. The balcony had great views of the water and ortigia. Highly recommend to anyone visiting Siracusa! "
United States
Aria
The price is HK$1,803
HK$2,073 total
includes taxes & fees
19 Oct - 20 Oct
Casa Miranda Boutique
A hotel room with a bed, a view of the sea, and a small table with a chair.

13. Eos Sea View Apartment

Eos Sea View Apartment
Santa Lucia
10.0 out of 10, Exceptional, (2 reviews)
"Great location and clean apartment."
United States
Siarhei
The price is HK$1,674
HK$1,908 total
includes taxes & fees
11 Oct - 12 Oct
Eos Sea View Apartment
A modern dining area with a white table, green chairs, and a potted plant.

14. San Nicola Rooms Siracusa

San Nicola Rooms Siracusa
Santa Lucia
9.2 out of 10, Wonderful, (10 reviews)
"The breakfast was great! The hosts were super friendly and helpful!"
United States
Lin
The price is HK$934
HK$1,065 total
includes taxes & fees
3 Oct - 4 Oct
San Nicola Rooms Siracusa
A balcony with a table set for two, a chair, and a view of a building with multiple windows and balconies.

15. B&B Nike

B&B Nike
Santa Lucia
8.8 out of 10, Excellent, (91 reviews)
"Great location and comfortable stay!"
United States
Rosa
The price is HK$641
HK$731 total
includes taxes & fees
25 Oct - 26 Oct
B&B Nike
A bedroom with a stone wall, a bed with a wooden headboard, a tray with a plant, and a window with curtains.

16. B&B Siracusa

B&B Siracusa
Santa Lucia
9.0 out of 10, Wonderful, (60 reviews)
"Good location, very modern clean accommodation."
Canada
Malcolm
The price is HK$617
HK$703 total
includes taxes & fees
22 Oct - 23 Oct
B&B Siracusa
A table with two wine glasses and a decorative item, viewed through a window overlooking a parking area with cars and greenery.

17. Gymnasium

Gymnasium
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (42 reviews)
"Nice kitchen area, centrally located."
United States
Richard
The price is HK$460
HK$524 total
includes taxes & fees
5 Oct - 6 Oct
Gymnasium
A marina with numerous boats docked, a clear sky, and a building with outdoor seating.

18. Regina Margherita

Regina Margherita
Santa Lucia
7.8 out of 10, Good, (17 reviews)
"The area is so close to the Ortigia Island where the beautiful cathedral and Doumo are. Lovely walk around the entire island and areas to go in the water If you like. Many dining options and shopping too. Wonderful area!"
United States
Laura
The price is HK$606
HK$691 total
includes taxes & fees
21 Oct - 22 Oct
Regina Margherita
A balcony with a table set for tea, a book, and a view of a building and water.

19. Hotel Mediterraneo

Hotel Mediterraneo
3.0 star property
Santa Lucia
7.8 out of 10, Good, (125 reviews)
"Very friendly and helpful staff."
United States
David
The price is HK$789
HK$900 total
includes taxes & fees
17 Oct - 18 Oct
Hotel Mediterraneo
A bedroom with a bed, a desk, a chair, a television, and a mirror.

20. Fortuna Guest House

Fortuna Guest House
1.0 star property
Santa Lucia
9.2 out of 10, Wonderful, (20 reviews)
"Hotel was perfect for our 5 day stay,great location within walking distance to supermarkets and city centre. Antonino was a great host and provided clear communication for checking in and any questions about the place. Would highly recommend and visit again in the future."
Italy
Nello
The price is HK$884
HK$1,008 total
includes taxes & fees
7 Oct - 8 Oct
Fortuna Guest House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santa Lucia

Find the best Santa Lucia areas for the activities you enjoy most.
A historic waterfront with a stone bridge, illuminated buildings, and a calm water body.

Ortigia

Ortigia is popular for its seaside views, and if you're looking for more to see and do, you might think about a trip to Teatro dei Pupi or Cathedral of Syracuse.

A natural rock arch over a body of water with people paddling in kayaks.

Grottasanta

Grottasanta is noteworthy for its historical sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

Ancient ruins with a large amphitheater surrounded by trees.
Photo by William Keller
Open Photo by William Keller

Neapolis

While visiting Neapolis, you might make a stop by sights like Roman Amphitheatre of Syracuse and Archaeological Park of Neapolis.

An ancient amphitheater with stone ruins and a grassy field.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider stopping by Ionian Sea while you're exploring the neighbourhood.

An aerial view of a coastal city with a prominent fortified structure and a densely built urban area in the background.

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

Top Santa Lucia Hotel Reviews

Grande Albergo Alfeo

Grande Albergo Alfeo

10/10 Excellent
"Great hotel and location for arriving by train/bus and walking distance to all the sites. Front desk staff great and provided early access to our room at check-in. Room was very comfortable and a good size. Breakfast had great options."
Deborah G 1-night trip
Posted 19 hours ago
Grande Albergo Alfeo

Frequently asked questions

What is Santa Lucia like?
Santa Lucia is a neighbourhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Make sure that you visit Porto Piccolo and Ionian Sea while you're in the neighbourhood.
Where is the best hotel for a stay in Santa Lucia?
Based on our traveller data, Grande Albergo Alfeo is one of the top choices for your stay in Santa Lucia. This hotel offers free breakfast and a restaurant. Other good choices for your stay in the area include Caportigia Boutique Hotel and Fortaleza Charme House.
How many hotels will I find in Santa Lucia?
Expedia has 314 hotels and other accommodation options in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.
If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review the best options available in Santa Lucia.
What are the top things to see and do in Santa Lucia?
Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops worth a visit in the neighbourhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.

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