Panama Canal Zone 4 Stars Hotels

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Check availability on Panama Canal Zone 4 Star Hotels

Tonight
29 Dec - 30 Dec
Tomorrow
30 Dec - 31 Dec
This weekend
2 Jan - 4 Jan
Next weekend
9 Jan - 11 Jan

Our top choices for Panama Canal Zone 4-star hotels

Outdoor pool, pool umbrellas, pool loungers
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
Tocumen
8.4 out of 10, Very good, (2331)
"Great breakfast was included and the airport shuttle was conveniently located "
United States
Adrienne
The price is HK$855
HK$941 total
includes taxes & fees
29 Jan - 30 Jan 2026
Crowne Plaza Panama Airport by IHG
Front of property
Megapolis Hotel Panamá

Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.4 out of 10, Very good, (1322)
"Lovely breakfast and very clean and friendly staff!!!"
United States
Ravindra
The price is HK$2,062
HK$2,269 total
includes taxes & fees
3 Jan - 4 Jan 2026
Megapolis Hotel Panamá
View from property
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1003)
"Breakfast was excellent"
United States
rosa
The price is HK$1,220
HK$1,342 total
includes taxes & fees
13 Jan - 14 Jan 2026
Las Americas Golden Tower Panama
Terrace/patio
Marriott Panama Hotel

Marriott Panama Hotel

Marriott Panama Hotel
4.0 star property
Panama City
9.0 out of 10, Wonderful, (1000)
"Great hotel and staff!"
United States
Catherine
The price is HK$1,181
HK$1,299 total
includes taxes & fees
30 Jan - 31 Jan 2026
Marriott Panama Hotel
Front of property
Novotel Panama City

Novotel Panama City

Novotel Panama City
4.0 star property
Bella Vista
9.2 out of 10, Wonderful, (1049)
"The hotel was very nice and the staff was great."
United States
Cena
The price is HK$846
HK$931 total
includes taxes & fees
11 Jan - 12 Jan 2026
Novotel Panama City
Restaurant
Studio Coliving

Studio Coliving

Studio Coliving
4.5 star property
Bella Vista
7.8 out of 10, Good, (585)
"Staff very helpful "
United States
Jean
Studio Coliving
Exterior
Decapolis Hotel Panama City

Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1468)
"Excellent stay. Wonderful staff, good location and excellent breakfast"
United States
Michael
The price is HK$1,093
HK$1,202 total
includes taxes & fees
2 Jan - 3 Jan 2026
Decapolis Hotel Panama City
Outdoor pool, pool umbrellas, pool loungers
Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1130)
"The room was clean and the location was great."
United States
Wendy
The price is HK$859
HK$945 total
includes taxes & fees
7 Jan - 8 Jan 2026
Ramada Plaza by Wyndham Panama Punta Pacifica
Front of property – evening/night
American Trade Hotel

American Trade Hotel

American Trade Hotel
4.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (614)
"The staffs are very nice, friendly and helpful"
United States
Dianne Marie
The price is HK$2,266
HK$2,493 total
includes taxes & fees
13 Jan - 14 Jan 2026
American Trade Hotel
Terrace/patio
Sheraton Grand Panama

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (999)
"Was amazing food was delicious and stay was great "
United States
Amanda
The price is HK$1,042
HK$1,146 total
includes taxes & fees
9 Jan - 10 Jan 2026
Sheraton Grand Panama
Outdoor pool
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
4.0 star property
Bella Vista
9.0 out of 10, Wonderful, (629)
"Location is just ok as well as the breakfast."
Canada
john
The price is HK$570
HK$846 total
includes taxes & fees
4 Jan - 5 Jan 2026
Waymore Hotel Spa & Casino
Breakfast, lunch, dinner served; international cuisine
Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
Cerro Viento
8.8 out of 10, Excellent, (1008)
"Location Location Location! Clean, safe, beautiful. Loved it!"
United States
Sharon Gobern Dorray and Jason
The price is HK$852
HK$937 total
includes taxes & fees
12 Jan - 13 Jan 2026
Courtyard by Marriott Panama Metromall
Exterior
Holiday Inn Panama Distrito Financiero by IHG

Holiday Inn Panama Distrito Financiero by IHG

Holiday Inn Panama Distrito Financiero by IHG
4.0 star property
Bella Vista
8.8 out of 10, Excellent, (1005)
"Clean room , friendly staff "
United States
Junique
The price is HK$622
HK$727 total
includes taxes & fees
16 Jan - 17 Jan 2026
Holiday Inn Panama Distrito Financiero by IHG
47-inch flat-screen TV with cable channels, TV
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
Casco Viejo
9.2 out of 10, Wonderful, (1011)
"Nice hotel in the historic center, excellent location for sightseeing and walking around at night."
United States
Antonio
The price is HK$2,769
HK$3,046 total
includes taxes & fees
2 Jan - 3 Jan 2026
Central Hotel Panama Casco Viejo
Exterior
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1002)
"Staff was very helpful. Great location."
United States
John
The price is HK$720
HK$792 total
includes taxes & fees
16 Jan - 17 Jan 2026
Courtyard by Marriott Panama Multiplaza Mall
Outdoor pool, open 6:00 AM to 11:00 PM, pool umbrellas, pool loungers
Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (544)
"Room was clean and staff was courteous."
United States
John
The price is HK$1,248
HK$1,373 total
includes taxes & fees
30 Jan - 31 Jan 2026
Residence Inn by Marriott Panama City
Restaurant
Hyatt Regency Panama City

Hyatt Regency Panama City

Hyatt Regency Panama City
4.5 star property
Bella Vista
10.0 out of 10, Exceptional, (142)
"Great hotel fair price"
United States
Santiago
The price is HK$1,218
HK$1,340 total
includes taxes & fees
3 Jan - 4 Jan 2026
Hyatt Regency Panama City
Front of property
Hotel San Felipe

Hotel San Felipe

Hotel San Felipe
4.0 star property
Casco Viejo
9.4 out of 10, Exceptional, (257)
"Nice hotel, perfect area in the old quarter. Clean, comfortable, great staff. Highly recommend!"
Canada
Neil
The price is HK$1,102
HK$1,212 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel San Felipe
Daily full breakfast for a fee
Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
4.5 star property
Casco Viejo
9.8 out of 10, Exceptional, (259)
"Great location!"
United States
Erik
The price is HK$2,609
HK$2,870 total
includes taxes & fees
10 Jan - 11 Jan 2026
Hotel La Compañía Casco Antiguo
2 outdoor pools, pool umbrellas, pool loungers
Radisson Hotel Panama Canal

Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
4.5 star property
Amador
8.4 out of 10, Very good, (1002)
"Unbeatable location if your visit is all about the Panama Canal. "
United States
Vitaliy
The price is HK$621
HK$683 total
includes taxes & fees
30 Jan - 31 Jan 2026
Radisson Hotel Panama Canal
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Panama Canal Zone.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama
The price is HK$952 per night from 12 Jan to 13 Jan
HK$952
HK$1,047 total
12 Jan - 13 Jan 2026
includes taxes & fees
9/10 Wonderful! (4,723 reviews)
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PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Panama Canal Zone

Explore the relaxing area of Panama Canal Zone—rainforests, golf courses and popular sights like Albrook Shopping Mall.

See all hotels in Panama Canal Zone
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Top Panama Canal Zone Hotel Reviews

Novotel Panama City

Novotel Panama City

10/10 Excellent
"Bien ubicado bien servicio "
ADRIANA CORRALES 3-night trip
Posted 3 days ago
Novotel Panama City

Frequently asked questions

What are the best 4-star hotels in Panama Canal Zone?
Melia Panama Canal is a 4-star hotel in Panama Canal Zone that's popular among Expedia guests. Concierge services and a terrace are just a couple of its amenities. Travellers also recommend Radisson Colon 2,000 Hotel & Casino. From a swimming pool to spa facilities, it comes with conveniences that cater to every aspect of your relaxation and enjoyment.
How much does it cost to stay in a 4-star hotel in Panama Canal Zone?
To lock in a 4-star hotel in Panama Canal Zone that fits your budget, use Expedia's search and sort filters. Take a look at the availability during your holiday dates and use our pricing filter to set your limit. You can also sort your results by the most economical property first.

  • Search for the lowest price from HK$1,047

What's the difference between 5-star and 4-star hotels in Panama Canal Zone?
Treat yourself to luxury living during your Panama Canal Zone escape by choosing a 4-star hotel. As well as featuring upscale accommodation, these properties are usually filled with amenities, including complimentary bathrobes, large beds and plenty more. A 5-star hotel will go the extra mile to make your stay an even more indulgent and unforgettable one. Concierge assistance, elegant furnishings and world-class dining are a few of the superior conveniences and services you'll likely get access to.