A modern glass building with a curved facade and a sign reading "The Kentucky Center".

Southern Indiana 4 Stars Hotels

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Check availability on Southern Indiana 4 Star Hotels

Tonight
8 Oct - 9 Oct
Tomorrow
9 Oct - 10 Oct
This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

Our top choices for Southern Indiana 4-star hotels

A modern interior with large windows offering a city view, a circular light fixture, and leather seating.
A modern bar with a long counter, multiple shelves of liquor bottles, and cushioned bar stools.
A balcony with a view of a river, a bridge, and a cityscape.
A spacious room with a large dining table, comfortable seating, a sofa, and a view of a bridge.

1. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
Downtown Louisville
United States
Saud
HK$1,139
HK$1,340 total
includes taxes & fees
25 Oct - 26 Oct
Galt House Hotel Trademark Collection by Wyndham
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.
A modern building entrance with a glass facade, wooden ceiling, and illuminated fixtures.
A rooftop bar with outdoor seating, including sofas and chairs, and a bar area with a television screen.
A modern interior with a fireplace, bookshelves, and seating areas.

2. Omni Louisville Hotel

Omni Louisville Hotel
Downtown Louisville
United States
Samantha
HK$1,993
HK$2,345 total
includes taxes & fees
30 Oct - 31 Oct
Omni Louisville Hotel
A grand lobby with ornate columns, plush seating, and a chandelier.
A grand lobby with ornate ceiling and chandeliers, a large vase, and a seating area with multiple sofas and armchairs.
A grand lobby with ornate ceiling, large windows, and classic furniture.
A grand dining area with ornate ceiling, chandeliers, and a bar area with a sign reading "Cigar Bar".

3. The Brown Hotel

The Brown Hotel
Downtown Louisville
United States
Meghan
HK$922
HK$1,085 total
includes taxes & fees
28 Oct - 29 Oct
The Brown Hotel
A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.
A modern hotel room with a living area, a dining area, and a bedroom.
An indoor swimming pool with clear water, surrounded by white marble walls and columns, and furnished with lounge chairs and tables.
A hotel dining area with long tables, booths, and a bar.

4. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
Downtown Louisville
United States
Frances
HK$1,152
HK$1,355 total
includes taxes & fees
29 Oct - 30 Oct
Embassy Suites Louisville Downtown
A spacious lobby with a central escalator, comfortable seating areas, and modern lighting fixtures.
An outdoor seating area with wicker furniture, wooden tables, and large lamps.
A modern hotel exterior with outdoor seating, a glass canopy, and a visible sign for the Hyatt Regency.
A modern living room with a sofa, armchairs, a coffee table, and a dining area with a table and chairs.

5. Hyatt Regency Louisville

Hyatt Regency Louisville
Downtown Louisville
United States
Lester
HK$1,193
HK$1,403 total
includes taxes & fees
29 Oct - 30 Oct
Hyatt Regency Louisville
A modern building with a restaurant on the ground floor, featuring large windows and outdoor seating.
A modern bar area with glass partitions, bar stools, and a variety of bottles.
A reception area with marble counters, modern pendant lighting, and potted orchids.
A modern hotel room with a large window offering a city view, a cozy seating area with a sofa and chairs, a dining table with lamps, and a wooden floor.

6. Louisville Marriott Downtown

Louisville Marriott Downtown
Downtown Louisville
HK$1,748
HK$2,057 total
includes taxes & fees
7 Nov - 8 Nov
Louisville Marriott Downtown
A classical gold statue in front of a multi-story building with large windows and a brick facade.
A cozy room with wooden walls, a table with a lamp, and shelves displaying books and decorative items.
A steam fountain in a brick alleyway.
A cozy room with a geometric-patterned ceiling, a sofa, and a chair.

7. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
Downtown Louisville
United States
Matt
HK$1,261
HK$1,523 total
includes taxes & fees
8 Nov - 9 Nov
21c Museum Hotel Louisville
A room with a checkered floor, leather armchairs, a sofa, and a small table with a glass. There are windows with arched tops and a view of buildings outside.
A bar area with a wooden bar counter, two stools, a chandelier, and a mirror.
A brightly lit grocery store with yellow shelving and a central checkout counter.
A yellow coffee shop counter with a menu board above, displaying various coffee and food items.

8. Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
Downtown Louisville
United States
Tyler
HK$1,130
HK$1,330 total
includes taxes & fees
26 Oct - 27 Oct
Hotel Genevieve part of JdV by Hyatt
An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.
A multi-story hotel with a classic facade, large windows, and a modern glass building adjacent to it.
An outdoor dining area with tables and chairs, a green building facade, and a row of plants along the wall.
A bar with shelves of liquor bottles and a bartender preparing drinks.

9. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
Downtown Louisville
United States
Anthony
HK$1,858
HK$2,186 total
includes taxes & fees
29 Oct - 30 Oct
Hotel Distil, Autograph Collection
A cozy room with a green sofa, two small round tables, and a large mural of an angel on the wall.
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.
A building with a sign reading "THE GRADY" at the entrance.
A multi-level interior with a staircase, bookshelves, and a prominent sign reading "THE GRADY".

10. The Grady

The Grady
Downtown Louisville
United States
Bruce
HK$1,455
HK$1,712 total
includes taxes & fees
18 Oct - 19 Oct
The Grady
An outdoor seating area with sofas and tables, a fire feature, and a clock tower in the background.
A modern living room with a sofa, a coffee table, a side table with a plant, and a view of a building with a clock tower.
A modern hotel room with a large bed, a city view, and a unique headboard design.
A modern lobby with a central reception desk, seating area, and a large abstract wall art piece.

11. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Downtown Louisville
United States
Cameron
HK$1,538
HK$1,810 total
includes taxes & fees
18 Oct - 19 Oct
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
A modern living room with a fireplace, a coffee table with books, a jar of cookies, and a plate of cookies.
A spacious lobby with a modern staircase, a round table with vases, and comfortable seating areas.
A breakfast tray with croissants, fruit, coffee, and juice on a table by a window with a city view.
An outdoor pool area with lounge chairs, a fire pit, and a building with brick walls and windows.

12. DoubleTree by Hilton Evansville

DoubleTree by Hilton Evansville
Downtown Evansville
United States
Cindy
HK$794
HK$913 total
includes taxes & fees
1 Nov - 2 Nov
DoubleTree by Hilton Evansville
A historic hotel with ornate architecture, a grand entrance, and a red carpet leading to the doors.
A grand staircase with ornate railings and a marble floor, leading to a high-ceilinged lobby with decorative moldings and a chandelier.
A grand lobby with marble floors, a staircase, and a reception desk.
A bakery display with pastries and bread, a coffee station, and a Christmas tree in the background.

13. Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
Downtown Louisville
United States
DAVID
HK$1,292
HK$1,521 total
includes taxes & fees
29 Oct - 30 Oct
Seelbach Hilton Louisville Downtown
A modern hotel lobby with a reception desk, seating area, and a staircase leading to the upper floor.
A modern, well-lit room with a large bed, a green sofa, a small round table, and a kitchen area in the background.
A modern KFC building with large glass windows, a prominent sign, and a well-lit entrance area.
A modern bedroom with a bed, a blue sofa, a large rug, and a TV on the wall.

14. Stellar Suites

Stellar Suites
Downtown Louisville
United States
Kevin
HK$772
HK$1,306 total
includes taxes & fees
1 Nov - 2 Nov
Stellar Suites
A grand entrance with a staircase leading to a door, flanked by two lamp posts and a bench.
A covered porch with a brick wall, a wooden door, and a hanging light fixture.
A long table set with white tablecloths, gold chargers, and clear glassware.
A marble countertop with a tray of colorful glassware, a bottle, and two glasses. A framed painting hangs above, and two lamps are on either side.

15. The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B
New Albany
United States
Vickie J
HK$725
HK$819 total
includes taxes & fees
14 Oct - 15 Oct
The Pepin Mansion Historic B&B
A modern lounge with leather sofas, a coffee table, and a view of a classical building.
A modern interior with a wooden dining table, leather sofas, and a bar area with shelves.
A modern living room with a leather sofa, two coffee tables, and a chessboard. There are shelves with bottles and glasses, and a large window on the right.
A building with a sign reading "Pursuit Spirits Co." and a large window display.

16. The Reserve on Main

The Reserve on Main
Downtown Louisville
United States
De'Carlon
The Reserve on Main
A rooftop pool area with multiple lounge chairs and umbrellas, surrounded by a high-rise building with balconies.
A gym with exercise equipment, mirrors, and a TV screen.
A modern living room with a dining area, a blue sofa, a ceiling fan, and a view of a balcony.
A modern kitchen with white cabinets, stainless steel appliances, and a dining area with a table and chairs.

17. CozySuites at Nulu

CozySuites at Nulu
Downtown Louisville
United States
Jennifer
HK$667
HK$1,685 total
includes taxes & fees
13 Oct - 14 Oct
CozySuites at Nulu
A modern hotel with a 'Stay Apt Suites' sign, featuring a brick facade, large windows, and a parking lot.
A reception desk with a dark wood finish, a sign reading "stay apt SUITES", and a telephone.
In-room dining
Private kitchen

18. stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville
Clarksville
Canada
Darlene
stayAPT Suites Louisville North-Clarksville
A large, multi-story building with a prominent tower and multiple windows.
A cozy seating area with two leather armchairs and a small round table. A table lamp and a wine glass are on the table.
A large outdoor swimming pool with a Ferris wheel in the background.
A dining table set with placemats, folded napkins, cutlery, and a coffee cup.

19. Bourbon Barrel Inn Bed & Breakfast

Bourbon Barrel Inn Bed & Breakfast
Old Louisville
United States
jonathan
Bourbon Barrel Inn Bed & Breakfast
A modern kitchen with wooden cabinets, a black microwave, and a stainless steel refrigerator.
A two-story brick house with a garage, a front door, and a small front yard with a lawn and a few shrubs.
A kitchen with wooden cabinets, a refrigerator, a coffee maker, and a tiled backsplash.
A living room with a sofa, a coffee table, and a ceiling fan. There is a dining area with a table and chairs.

20. Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
Sellersburg
United States
Tammy
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
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A riverboat with multiple decks and passengers, docked near a bridge.

Top Southern Indiana Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Southern Indiana?
Based on reviews by our guests, Galt House Hotel Trademark Collection by Wyndham is among the best 4-star hotels in Southern Indiana. Situated in Louisville, it includes massage services and beauty services. Hyatt Regency Louisville is another sought-after option here. Also with a 4-star rating and offering premium bedding and designer toiletries, you're sure to have a comfortable stay.
How much does it cost to stay in a 4-star hotel in Southern Indiana?
To book a 4-star hotel in Southern Indiana that's within your budget, take advantage of Expedia's handy filters. Take a look at what's available during your preferred dates and use our pricing filter to set your limit. You can also sort your results by the most budget-friendly option first.
  • Search for the lowest price from HK$819
What's the difference between 5-star and 4-star hotels in Southern Indiana?
Give yourself the luxury treatment during your Southern Indiana escape by checking in to a 4-star hotel. As well as featuring upmarket surroundings, these properties are typically packed with amenities such as large beds, bathrobes and plenty more. A 5-star hotel will go the extra mile to make your stay an even more indulgent and memorable one. 24-hour concierge assistance, luxurious spas and world-class dining are a few of the exclusive services and conveniences you'll likely be able to enjoy.

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