A large suspension bridge, industrial cranes, and a calm river.

Panama Canal Zone 5 Stars Hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Panama Canal Zone 5 Star Hotels

Tonight
28 Aug - 29 Aug
Tomorrow
29 Aug - 30 Aug
This weekend
28 Aug - 30 Aug
Next weekend
4 Sept - 6 Sept

Our top choices for Panama Canal Zone 5-star hotels

A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.
A hotel room with a bed, a TV, a desk, and a view of the cityscape through a window.
A modern hotel room with a dining area, a TV, and a city view.
A spacious lobby with a central seating area, a chandelier, and a modern ceiling design.

1. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
Bella Vista
United States
Lori
HK$1,034
HK$1,138 total
includes taxes & fees
28 Sept - 29 Sept
Hotel Riu Plaza Panama
A person seated at a bar with a drink, in a room with a teal accent wall and hanging lights.
A tall, modern building with a prominent logo at the top, surrounded by other high-rise buildings in a cityscape.
A modern building with a rooftop lounge area, large windows, and a balcony overlooking a cityscape.
An outdoor seating area with wicker chairs and tables, large windows offering a city view at dusk.

2. Waldorf Astoria Panama

Waldorf Astoria Panama
Bella Vista
United States
Aysha
HK$2,084
HK$2,293 total
includes taxes & fees
27 Sept - 28 Sept
Waldorf Astoria Panama
A balcony with a table, chairs, and a view of a city skyline across a body of water.
A spacious lobby with a round coffee table, seating areas, and a large wall clock.
A spacious lobby with high ceilings, modern furniture, and decorative lighting fixtures.
A spacious living room with a high ceiling, large windows, and a decorative ceiling fan.

3. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
Casco Viejo
United States
Josh
HK$2,716
HK$2,988 total
includes taxes & fees
20 Sept - 21 Sept
Sofitel Legend Casco Viejo, Panama City
A modern hotel room with a sofa, a coffee table, a TV mounted on the wall, and a dining area with a table and chairs.
An indoor swimming pool with lounge chairs and red chairs, surrounded by lush greenery and a modern interior design.
A modern hotel entrance with a prominent 'Renaissance Hotel' sign, a well-lit outdoor area with a wooden structure, and a staircase leading to the upper floors.
The exterior of the Renaissance Hotel with a modern design, featuring a prominent 'R' logo, a geometric ceiling design, and a well-lit entrance area.

4. Renaissance Panama City Hotel

Renaissance Panama City Hotel
Bella Vista
United States
Tad Olivet Ottinger Welcome
HK$995
HK$1,095 total
includes taxes & fees
3 Sept - 4 Sept
Renaissance Panama City Hotel
A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.
A modern interior with a central seating area, potted plants, and a staircase.
A modern building with a sign reading 'HYATT REGENCY.'
A spacious hotel lobby with modern furniture, large windows, and a city view.

5. Hyatt Regency Panama City

Hyatt Regency Panama City
Bella Vista
United States
Deanna
HK$1,568
HK$1,724 total
includes taxes & fees
29 Aug - 30 Aug
Hyatt Regency Panama City
A hotel entrance with a central water feature, seating areas, and potted plants.
A spacious lobby with a wooden ceiling, a central wooden table surrounded by potted plants, and a marble wall with a large window in the background.
A pool with a central water feature, surrounded by seating areas and potted plants.
The entrance of The Santa Maria with a covered walkway and a view of the interior.

6. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Juan Diaz
United States
Maria Adriana Bravo
HK$2,107
HK$2,318 total
includes taxes & fees
3 Sept - 4 Sept
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
A modern restaurant with large windows offering a city view, warm lighting, and contemporary furniture.
A modern high-rise building with a prominent 'W' logo, surrounded by other buildings and a busy street at night.
A modern hotel room with a large bed, a desk, a chair, and a view of the cityscape.
A high-rise building with a rooftop pool area, surrounded by other buildings.

7. W Panama

W Panama
Bella Vista
United States
Anna Lee
HK$1,812
HK$1,993 total
includes taxes & fees
26 Sept - 27 Sept
W Panama
A poolside area with lounge chairs and a view of the ocean.
A modern bathroom with a large bathtub, two sinks, and a glass-enclosed shower area with a city view.
A terrace with seating and a view of the ocean.
A modern hotel room with a large bed, a chair, a nightstand with a lamp, and a view of the cityscape at dusk.

8. JW Marriott Panama

JW Marriott Panama
San Francisco
United States
Benjamin A
HK$2,063
HK$2,269 total
includes taxes & fees
26 Sept - 27 Sept
JW Marriott Panama
A hotel with a pool, beach, and palm trees.
A spacious lobby with a large seating area, a reception desk, and large windows offering a view of the ocean and palm trees.
A beachfront hotel with a large building, a beach, and a clear sky.
A large hotel with multiple towers, a central courtyard with a swimming pool, and surrounding landscaped areas.

9. The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
Veracruz
United States
Robert
HK$1,545
HK$1,699 total
includes taxes & fees
25 Sept - 26 Sept
The Westin Playa Bonita Panama
A modern hotel pool area with lounge chairs and a clear view of the ocean.
A modern bar area with seating and a view of the city.
A modern interior with a spiral staircase, a large window, and a seating area.
A marina with boats docked, a city skyline with illuminated buildings, and a visible moon in the sky.

10. Hilton Panama

Hilton Panama
Bella Vista
United States
William
HK$1,858
HK$2,043 total
includes taxes & fees
18 Sept - 19 Sept
Hilton Panama
A modern living room with a sofa, round black ottomans, and a vase of flowers. A cityscape is visible through the window.
A person performing a yoga pose in a living room with a large window and a sofa.
A cozy outdoor seating area with a wooden bench and white tables, surrounded by lush greenery and potted plants.
A bar area with a long counter, multiple bar stools, and a television screen. There are large windows providing natural light and a view of the outdoors.

11. Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
Bella Vista
United States
Steven
HK$1,757
HK$1,932 total
includes taxes & fees
6 Sept - 7 Sept
Bristol Panama, a Registry Collection Hotel

12. Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
United States
MARVIN
HK$1,866
HK$2,052 total
includes taxes & fees
20 Sept - 21 Sept
Megapolis Hotel Panamá

13. Waymore Hotel Spa and Casino

Waymore Hotel Spa and Casino
Bella Vista
HK$863
HK$949 total
includes taxes & fees
29 Aug - 30 Aug
Waymore Hotel Spa and Casino
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Panama Canal Zone.
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz Tocumen Panama
HK$925
HK$1,069 total
26 Sept - 27 Sept
includes taxes & fees
8.6/10 Excellent! (2,726 reviews)
Crowne Plaza Panama Airport by IHG
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Plaza de la Independencia Casco Viejo Panama City Panama
HK$1,438
HK$1,581 total
27 Sept - 28 Sept
includes taxes & fees
Central Hotel Panama Casco Viejo
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

Calle Augusto Samuel Boyd y Calle Eusebi Panama City
HK$670
HK$953 total
29 Aug - 30 Aug
includes taxes & fees
9/10 Wonderful! (1,099 reviews)
Waymore Hotel Spa & Casino
Still don't see what you're looking for?
See all properties in Panama Canal Zone.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Panama Canal Zone

Explore the relaxing area of Panama Canal Zone—rainforests, golf courses and popular sights like Albrook Shopping Mall.

See all hotels in Panama Canal Zone
A large steel bridge spanning a river with a cargo ship beneath it.

Top Panama Canal Zone Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"We stayed on the 30th floor and had an amazing view. The room was clean, comfortable, and housekeeping was done daily throughout our stay. The breakfast was a big spread and definitely something to look forward to. It’s probably better to go later rather than early, as the crowds seemed especially heavy during the earlier times. The front desk staff were very helpful whenever we had questions and made the stay feel easy and well supported. Overall, we really enjoyed our experience. Between the view, cleanliness, daily housekeeping, breakfast and helpful staff, we had a great stay and would definitely be happy to stay here again."
Tiffany 5-night trip
Posted 7 hours ago
Hotel Riu Plaza Panama
Hyatt Regency Panama City

Hyatt Regency Panama City

10/10 Excellent
"Very helpful staff and great amenities"
Hellen 1-night trip
Posted 17 hours ago
Hyatt Regency Panama City
Renaissance Panama City Hotel

Renaissance Panama City Hotel

10/10 Excellent
"I was very satisfied"
Jeffrey 4-night trip
Posted 3 days ago
Renaissance Panama City Hotel
Waldorf Astoria Panama

Waldorf Astoria Panama

10/10 Excellent
"Dede el ingress estuvimos super bien recibidos hasta el check in y en lahabitacion super bien el de say unto muy recommendable y gran atencion"
Gaudy 1-night trip
Posted 4 days ago
Waldorf Astoria Panama

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Panama Canal Zone?
The amount you pay for a 5-star hotel in Panama Canal Zone depends on factors such as when you want to go and the length of your trip. A top tip for scoring the best deal? Use our pricing filters to compare all of the available accommodation for your chosen dates.
  • Search for the lowest price per night from HK$953
What makes a hotel 5 stars in Panama Canal Zone?
Faultless guest service is integral to every 5-star hotel in Panama Canal Zone. From the moment you enter the lobby, staff ensure your every need is met, whether arranging valet parking or providing in-room massage treatments. Additionally, hotels have to offer upscale conveniences to obtain a 5-star rating. These can include deluxe baths, an on-site spa, pools, fine dining kitchens and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Panama Canal Zone?
Our filter tool is the best way to narrow down what you want. Select "5-star" and "All inclusive" to see the most upscale hotels in Panama Canal Zone where your meals, accommodation, activities and entertainment are included in the price. At these getaways, your trip is pure indulgence from the moment you step foot in the lobby.