Panama City Biomuseo Hotels: 2026 Limited-Time Hotel Deals @Expedia

A modern building with colorful geometric shapes and a clear blue sky.

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Our top choices for Biomuseo hotels

A spacious indoor courtyard with tiled flooring, multiple seating areas, and hanging plants.

A living room with a sofa, a coffee table with books, a chandelier, and a kitchen with wooden cabinets and granite countertops.

A room with a large window, a television mounted on the wall, and two chairs.

An open door revealing a balcony with a wrought iron railing, potted plants, and a window with a curtain.

1. La Isabela Suites

San Felipe, 2.5 km from Biomuseo

David

HK$1,234

HK$1,358 total

includes taxes & fees

25 Oct - 26 Oct

A balcony with a table, chairs, and a view of a city skyline across a body of water.

A spacious living room with a high ceiling, large windows, and a decorative ceiling fan.

A spacious lobby with a round coffee table, seating areas, and a large wall clock.

A hotel with a rooftop pool, lounge chairs, and a view of the sea.

2. Sofitel Legend Casco Viejo, Panama City

San Felipe, 2.5 km from Biomuseo

Jose

HK$3,244

HK$3,569 total

includes taxes & fees

1 Nov - 2 Nov

A multi-story building with ornate balconies, large windows, and decorative moldings.

A spacious hotel room with a large bed, a seating area with a sofa and chairs, a dining table, and a staircase.

A room with a white sofa, a wooden chair, a mirror, and a large window with curtains.

A spacious restaurant with high wooden ceilings, multiple tables and chairs, and a bar area with shelves of bottles and glasses.

3. Hotel Plaza Herrera

San Felipe, 2.4 km from Biomuseo

Christina

HK$2,010

HK$2,211 total

includes taxes & fees

25 Oct - 26 Oct

A hotel courtyard with a central lawn, surrounded by buildings with balconies and outdoor seating areas.

A modern living room with a sofa, a coffee table, and a TV mounted on the wall.

A restaurant with multiple dining tables, chairs, and a central water feature.

A rooftop terrace with tables and chairs, a view of two white towers, and a building with a large window.

4. Hotel La Compañía Casco Antiguo

San Felipe, 2.4 km from Biomuseo

Carlos A

HK$2,192

HK$2,411 total

includes taxes & fees

25 Oct - 26 Oct

A rooftop terrace with a hot tub, wooden deck, outdoor seating, and a view of a cityscape including a clock tower.

A restaurant interior with checkered flooring, wooden tables, wicker chairs, and hanging wicker lamps.

A multi-level interior with a checkered floor, wooden railings, and potted plants.

A room with a brick wall, a wooden staircase, and hanging pendant lights.

5. Amarla Boutique Hotel Casco Viejo Adults Only

San Felipe, 2.5 km from Biomuseo

Shanae

HK$1,629

HK$1,792 total

includes taxes & fees

9 Nov - 10 Nov

A multi-story hotel with a classic architectural design, featuring balconies and large windows.

A glass of white wine on a balcony railing overlooking a city street with buildings and cars.

A restaurant interior with a large indoor tree, tables, chairs, and a display of potted plants.

A spacious bedroom with a large bed, a chandelier, a bathroom with a bathtub, and a dining area.

6. La Concordia Boutique Hotel

San Felipe, 2.4 km from Biomuseo

Jadah

HK$1,783

HK$1,962 total

includes taxes & fees

6 Nov - 7 Nov

A spacious outdoor patio with wicker furniture, potted plants, and umbrellas providing shade.

A dimly lit restaurant with wooden decor, tables, and chairs arranged for dining.

A hotel with a covered entrance, multiple windows, and a balcony with plants.

A modern hotel lobby with beige sofas, marble flooring, and a reception desk.

7. Hotel San Felipe

San Felipe, 2.4 km from Biomuseo

RoseMarie

HK$1,228

HK$1,351 total

includes taxes & fees

27 Oct - 28 Oct

A historic building with multiple balconies and a statue of a man on horseback.

A spacious indoor area with high ceilings, large windows, and multiple dining tables.

A white building with multiple balconies, large windows, and decorative railings.

A restaurant with brick walls, arched windows, and a variety of seating arrangements including tables and chairs.

8. American Trade Hotel

San Felipe, 2.4 km from Biomuseo

Ashleigh-Ann

HK$1,925

HK$2,118 total

includes taxes & fees

1 Nov - 2 Nov

A spacious living area with a modern sofa, a wooden coffee table, and a staircase leading to an upper level.

A bedroom with a large bed, a ceiling fan, and multiple windows.

A spacious living area with a large TV, a stone accent wall, and a modern kitchen in the background.

A modern kitchen with white cabinets, a dining table with chairs, and a spiral staircase.

9. Casa Lefevre By Wynwood House

San Felipe, 2.6 km from Biomuseo

Selam

HK$965

HK$1,277 total

includes taxes & fees

2 Nov - 3 Nov

A multi-story building with balconies, arched windows, and decorative railings.

A multi-level atrium with wooden staircases, seating areas, and a decorative ceiling.

A building with a balcony and a street view.

A rooftop swimming pool with lounge chairs, potted plants, and a view of a city skyline including a prominent building with a dome.

10. Central Hotel Panama Casco Viejo

San Felipe, 2.5 km from Biomuseo

Moejha

HK$1,716

HK$1,888 total

includes taxes & fees

23 Nov - 24 Nov

A hotel room with a bed, a desk with a computer, a chair, a mirror, and a staircase.

A spacious living area with a staircase leading to a loft, a large mirror, and a television.

A living room with a patterned sofa, a matching ottoman, a large mirror, and a staircase leading to an outdoor area.

An outdoor seating area with cushioned chairs and tables, a covered seating area, and a wall with hanging plants.

11. Hotel Bardot Boutique

San Felipe, 2.5 km from Biomuseo

Luz

HK$743

HK$817 total

includes taxes & fees

22 Nov - 23 Nov

A modern indoor pool area with clear blue water, lounge chairs, and a wall of plants.

A modern kitchen with a central island, stainless steel appliances, and a dining area with black chairs.

A balcony with a view of the sea, a table with a vase and a candle, and a chair.

A modern kitchen with a large window, a dining area with chairs, and a view of the city.

12. Casco View Life Residences

Santa Ana, 2.4 km from Biomuseo

Arshak Andrew

HK$656

HK$957 total

includes taxes & fees

25 Oct - 26 Oct

A spacious living room with blue sofas, a marble coffee table, and framed pictures on the walls.

A blue building with arched windows and balconies, labeled 'Magnolia.'

A bedroom with a large bed, white walls, and a view of a building through arched windows.

13. Hotel Magnolia Boutique

San Felipe, 2.5 km from Biomuseo

Boris

HK$730

HK$803 total

includes taxes & fees

22 Nov - 23 Nov

A hotel room with a large bed, a painting on the wall, a door, and a small table with a lamp.

A modern living room with a purple wall, two abstract paintings, a white sofa with colorful cushions, a wooden coffee table with books and bottles, and patterned floor tiles.

A restaurant interior with tables and chairs, decorative hanging lights, and a mural on the wall.

A room with a kitchenette, a sofa, a bed, and a mural with the phrase "Just Breathe".

14. Tantalo Hotel

San Felipe, 2.5 km from Biomuseo

Cynthia

HK$610

HK$670 total

includes taxes & fees

22 Nov - 23 Nov

An outdoor patio area with wicker furniture and glass-top tables, surrounded by lush greenery and a view of the interior.

A living room with wicker furniture, a television, and a sliding glass door leading to a balcony with plants.

A rectangular swimming pool with a tiled edge, surrounded by a tiled patio area.

A hotel room with a bed, a ceiling fan, a TV, a refrigerator, and a window with curtains.

15. The Balboa Inn

Balboa, 2.7 km from Biomuseo

Rhonda

HK$577

HK$635 total

includes taxes & fees

26 Oct - 27 Oct

A resort with a pool area, lounge chairs, and a view of a bridge at night.

A reception desk with three staff members, a green patterned wall, a wooden reception area, and a large plant.

A modern hotel lobby with round tables, potted plants, and ceiling vents.

A restaurant with a long wooden table, chairs, and a buffet setup.

16. Radisson Hotel Panama Canal

Amador, 1.5 km from Biomuseo

Si Ming

HK$640

HK$704 total

includes taxes & fees

6 Nov - 7 Nov

A multi-story building with balconies adorned with string lights, a sign reading "ZABAH", and a storefront named "CORCHO".

A modern bathroom with a glass shower enclosure, a wooden door, and a herringbone-patterned floor.

A modern bathroom with a glass shower enclosure, a herringbone wooden floor, and a stone wall feature.

17. Corcho

San Felipe, 2.5 km from Biomuseo

Ashley

HK$748

HK$823 total

includes taxes & fees

31 Oct - 1 Nov

A modern kitchen with a dining area, large windows, and a view of the city.

A modern kitchen with a built-in island, stainless steel appliances, and black bar stools.

A modern kitchen with a built-in oven and microwave, a living area with a sofa and ottomans, and a stone wall with a television.

A modern restaurant with a sushi bar, bar seating, and a mix of indoor and outdoor dining areas.

18. La Cuadra by Wynwood House

El Chorrillo, 2.3 km from Biomuseo

Lise Jane

HK$1,003

HK$1,339 total

includes taxes & fees

27 Oct - 28 Oct

A living room with a sofa, coffee table, TV, and artwork on the walls.

A high-rise building with a glass elevator shaft, a metal railing on the balcony, and a sign with the letters "OASIS".

A balcony with a view of a cityscape, including a river and a bridge.

A spacious living area with a patterned rug, a round ottoman, a sofa, and a coffee table. There is a door leading to another room and a wall-mounted security camera.

19. Oasis Hotel

San Felipe, 2.5 km from Biomuseo

Charles

HK$466

HK$512 total

includes taxes & fees

12 Nov - 13 Nov

A balcony with a view of a marina and a hilly landscape.

A modern hotel lobby with a reception desk, seating area, and a large window overlooking the city.

A couple in white robes on a bed with a champagne bottle and ice bucket.

A modern building with a large metallic sculpture in the foreground, surrounded by palm trees and a clear blue sky.

20. The Beach House

Amador, 2.5 km from Biomuseo

JULIE

HK$540

HK$594 total

includes taxes & fees

26 Oct - 27 Oct

View all properties

Compare popular hotels close to Biomuseo

Property	Property class	Guest rating
La Isabela Suites	10.0 Exceptional 212 reviews	View
Sofitel Legend Casco Viejo, Panama City	9.8 Exceptional 766 reviews	View
Hotel Plaza Herrera	9.8 Exceptional 51 reviews	View
Hotel La Compañía Casco Antiguo	9.8 Exceptional 365 reviews	View
Amarla Boutique Hotel Casco Viejo Adults Only	9.6 Exceptional 146 reviews	View

Top Biomuseo Hotel Reviews

Hotel Riu Plaza Panama

10/10 Excellent

"Me gusta la ubica o, muy conveniente. El personal muy atento. El desayuno espectacular"

Central Hotel Panama Casco Viejo

8/10 Good

"Hotel is set in a beautiful square facing the cathedral. Staff all were very helpful. Prices for food and drinks are very reasonable for a hotel. My only complaint was at times the floor drains stunk in the bathroom. We didn’t let this spoil our week and would go back."

Hotel San Felipe

10/10 Excellent

"Loved our stay! Central, clean, wonderful staff"

Hotel Plaza Herrera

10/10 Excellent

"Perfect location in the middle of the historic old city. Excellent property condition (just renovated), spacious rooms. The staff was extremely helpful and friendly. A good breakfast to order is included at the downstairs restaurant. The only negative point is the absence of an elevator, so you will have to run up and down the stairs."

La Palma Experience

8/10 Good

"Recibimos buena atención, aunque se presentaron algunos inconvenientes como que el aire acondicionado no enfría a suficiente o que la presión de agua no llegaba a la habitacion, nos ofrecieron cambio de habitaciones lo cual nos permitió evaluar todas las opciones. Yo regreso, pero si me gustaría un menú más variado en sus desayunos, almuerzos y cenas."

w* | Upscale 2BR in Casco Antiguo w/ View

10/10 Excellent

"Liked the cleanliness, amenities and property condition. Property location was centrally located with easy access to restaurants, grocery store and more. Watching the Pacific tide was really amasing. It was really a nice stay."

Casa Love by Wynwood House

10/10 Excellent

"The unit we stayed in was large and fully equipped, with a balcony and a full kitchen. The building was secure and conveniently located within walking distance to everything in casco viejo. There are lots of shops and restaurants nearby and we felt mostly safe walking around. The only issue we had was that the code to our lockbox didn’t work when we arrived. However, we texted the property staff and they were able to give us another code that worked right away. The internet in the unit worked fine, but be sure to have a data plan or eSIM so that you can connect with the property and order Ubers, especially when you first get in, as the WiFi in the airport can be very spotty."

Casa La Costa By Wynwood House

10/10 Excellent

"Very nice place, clean and big, location is very good to walk around restaurants."

Other attractions near Biomuseo

Amador Causeway

9.0/10 (1,902 reviews)

You can learn about the history of Ancon with a visit to Amador Causeway. Stroll along the seaside or visit the shops in this vibrant area.

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Amador Convention Center

9.2/10 (23 reviews)

Learn about the events happening in Amador Convention Center during your trip to Ancon. While in this walkable area, you can savour the top-notch restaurants.

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Punta Culebra Nature Center

9.0/10 (14 reviews)

Enjoy an outing to Punta Culebra Nature Center during your stay in Ancon. Stroll along the seaside in this vibrant area or visit its top-notch restaurants.

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Maracana Stadium

8.0/10 (32 reviews)

Catch an event at Maracana Stadium during your trip to Panama City. Visit the shops and top-notch restaurants in this vibrant area.

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Smithsonian Tropical Research Institute Punta Culebra

9.2/10 (19 reviews)

You can spend time exploring the galleries in Smithsonian Tropical Research Institute Punta Culebra in Ancon. Amble around this vibrant area's seaside and enjoy its top-notch restaurants.

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Danilo Perez Foundation

Enjoy the student vibe at Danilo Perez Foundation as part of your travels around Panama City. Visit the shops and top-notch restaurants in this vibrant area.

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Plaza de Francia

10.0/10 (1 review)

You can learn about the history of Panama City when you stop by Plaza de Francia. Visit the shops and top-notch restaurants in this vibrant area.

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Mola Museum

You can spend time exploring the galleries in Mola Museum in Panama City. You can enjoy the bars while in the area.

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Frequently asked questions

What's the area like around Biomuseo?

Biomuseo is located in a vibrant area of Ancon known for its array of dining options and major shopping area. You'll find 1260 hotels and other accommodations within a few miles for a convenient home base.

What's the best hotel to stay near Biomuseo?

Radisson Hotel Panama Canal is one of the top choices for your stay based on our traveller data, and this hotel offers 2 outdoor pools and 2 restaurants. It's located just a short 0.9 mi (1.5 km) from Biomuseo. Another good choice is La Palma Experience, located just 0.7 mi (1.1 km) away.

How many hotels are there near Biomuseo?

Expedia has 1260 hotels and other accommodation options a few miles from Biomuseo.

If I need to cancel the hotel reservation for my stay near Biomuseo, will I receive a refund?

Yes, you'll find most room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to view the best deals near Biomuseo.

What can I see and do near Biomuseo?

Interoceanic Canal Museum, Mola Museum and Museum of History Panama feature a variety of fascinating exhibits to see while you're in town. Sights like Panama Canal Railway, Iglesia del Carmen and Paseo de Las Bovedas are must-sees while exploring the area. You can catch a show at National Theater, Anita Villalaz Theater and Amador Theater.

Panama City Biomuseo Hotels

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Biomuseo hotels

1. La Isabela Suites

2. Sofitel Legend Casco Viejo, Panama City

3. Hotel Plaza Herrera

4. Hotel La Compañía Casco Antiguo

5. Amarla Boutique Hotel Casco Viejo Adults Only

6. La Concordia Boutique Hotel

7. Hotel San Felipe

8. American Trade Hotel

9. Casa Lefevre By Wynwood House

10. Central Hotel Panama Casco Viejo

11. Hotel Bardot Boutique

12. Casco View Life Residences

13. Hotel Magnolia Boutique

14. Tantalo Hotel

15. The Balboa Inn

16. Radisson Hotel Panama Canal

17. Corcho

18. La Cuadra by Wynwood House

19. Oasis Hotel

20. The Beach House

Compare popular hotels close to Biomuseo

Top Biomuseo Hotel Reviews

Hotel Riu Plaza Panama

Central Hotel Panama Casco Viejo

Hotel San Felipe

Hotel Plaza Herrera

La Palma Experience

w* | Upscale 2BR in Casco Antiguo w/ View

Casa Love by Wynwood House

Casa La Costa By Wynwood House

Other attractions near Biomuseo

Amador Causeway

Amador Convention Center

Punta Culebra Nature Center

Maracana Stadium

Smithsonian Tropical Research Institute Punta Culebra

Danilo Perez Foundation

Plaza de Francia

Mola Museum

Frequently asked questions