A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

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Our top choices for Defiance apartments

1. Great for Business Travelers! Pool + Gym

Great for Business Travelers! Pool + Gym
O'Fallon
The price is HK$1,331
HK$1,766 total
includes taxes & fees
12 Sept - 13 Sept
Great for Business Travelers! Pool + Gym

2. Stylish1BRStudioCleanQuietandCozy

Stylish1BRStudioCleanQuietandCozy
Saint Charles
10.0 out of 10, Exceptional, (3 reviews)
"Room was very clean with little to no issues at all. Host was super easy to work with and get information from. This spot is within 15-20minutes OR LESS to anything you’d need to do in the ofallon and surrounding areas. I’d book it again if I needed to."
United States
Mike S.
The price is HK$619
HK$2,034 total
includes taxes & fees
3 Sept - 4 Sept
Stylish1BRStudioCleanQuietandCozy

3. 2nd Street Loft - Riverview

2nd Street Loft - Riverview
Washington
10.0 out of 10, Exceptional, (15 reviews)
"Beautiful loft! Great location, walking distance to several restaurants on the river . "
United States
Christy D.
The price is HK$669
HK$1,364 total
includes taxes & fees
3 Sept - 4 Sept
2nd Street Loft - Riverview

4. Studio, sleeps 4, patio, short drive to Ski Resort, Six Flags & concert venues

Studio, sleeps 4, patio, short drive to Ski Resort, Six Flags & concert venues
Ballwin
7.8 out of 10, Good, (23 reviews)
"Nice and roomy place! The shower was a little messy when we went but everything else wemt well"
United States
alex h.
Studio, sleeps 4, patio, short drive to Ski Resort, Six Flags & concert venues

5. 2nd Street -Deck Suite (back entrance)

2nd Street -Deck Suite (back entrance)
Washington
10.0 out of 10, Exceptional, (9 reviews)
"Great comfortable mini apartment style."
United States
Ozzy
The price is HK$655
HK$1,394 total
includes taxes & fees
3 Sept - 4 Sept
2nd Street -Deck Suite (back entrance)

6. Family Friendly w/ Game Room in Quiet Neighborhood

Family Friendly w/ Game Room in Quiet Neighborhood
Wentzville
10.0 out of 10, Exceptional, (2 reviews)
"Nice house for our week in Lake St. Louis area. Accurate description of what you are getting and clean house. Would stay again if we are back in the area"
United States
Campbell W.
The price is HK$1,686
HK$3,717 total
includes taxes & fees
3 Sept - 4 Sept
Family Friendly w/ Game Room in Quiet Neighborhood

7. Dog-Friendly 2BR | Walk to Main Street

Dog-Friendly 2BR | Walk to Main Street
Saint Charles
8.0 out of 10, Very good, (5 reviews)
"The best price-value ratio. Quiet neighborhood, close to the city center."
United States
Tamas P.
The price is HK$754
HK$2,171 total
includes taxes & fees
7 Sept - 8 Sept
Dog-Friendly 2BR | Walk to Main Street

8. 2 Queen Beds | Non-Smoking, Kitchen

2 Queen Beds | Non-Smoking, Kitchen
Westport
9.8 out of 10, Exceptional, (38 reviews)
"Fantastic place!"
United States
Anonymous traveller
The price is HK$474
HK$550 total
includes taxes & fees
1 Oct - 2 Oct
2 Queen Beds | Non-Smoking, Kitchen

9. Pet-Friendly Duplex | Historic Main

Pet-Friendly Duplex | Historic Main
St. Charles Historic District
10.0 out of 10, Exceptional, (25 reviews)
"Great location"
United States
todd p.
The price is HK$1,058
HK$2,172 total
includes taxes & fees
7 Sept - 8 Sept
Pet-Friendly Duplex | Historic Main

10. 6th street 101 - Walk to Main St

6th street 101 - Walk to Main St
St. Charles Historic District
10.0 out of 10, Exceptional, (3 reviews)
"Excellent"
United States
Scott N.
The price is HK$776
HK$2,253 total
includes taxes & fees
3 Sept - 4 Sept
6th street 101 - Walk to Main St

11. Amazing Renovated Historic Loft on Main Street

Amazing Renovated Historic Loft on Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (68 reviews)
"Lovely accommodations, very clean, well equipped, great location. "
United States
Emily B.
The price is HK$981
HK$2,040 total
includes taxes & fees
3 Sept - 4 Sept
Amazing Renovated Historic Loft on Main Street

12. Historic Main Street Studio | Dog-Friendly

Historic Main Street Studio | Dog-Friendly
St. Charles Historic District
9.2 out of 10, Wonderful, (37 reviews)
"Had a wonderful stay. It was a Monday night so parking was very easy and the room was clean and comfortable. I would recommend this place 100% "
United States
Sarah C.
The price is HK$677
HK$1,594 total
includes taxes & fees
7 Sept - 8 Sept
Historic Main Street Studio | Dog-Friendly

13. The Lofts of North Main Street

The Lofts of North Main Street
St. Charles Historic District
9.6 out of 10, Exceptional, (188 reviews)
"It was great! Clean and great communication with host."
United States
Natalie H.
The price is HK$981
HK$2,064 total
includes taxes & fees
3 Sept - 4 Sept
The Lofts of North Main Street

14. The Global Getaway | World-Inspired 2-Bedroom Stay

The Global Getaway | World-Inspired 2-Bedroom Stay
St. Charles Historic District
10.0 out of 10, Exceptional, (1 review)
"Perfect location to Main Street.Hosts were easy to communicate with.No issues with the unit"
United States
Tony M.
The price is HK$865
HK$2,359 total
includes taxes & fees
6 Sept - 7 Sept
The Global Getaway | World-Inspired 2-Bedroom Stay

15. Prime Loft of Main Street

Prime Loft of Main Street
St. Charles Historic District
9.8 out of 10, Exceptional, (116 reviews)
"Host was great. The cutest place in the perfect spot! "
United States
Anonymous traveller
The price is HK$981
HK$2,040 total
includes taxes & fees
7 Sept - 8 Sept
Prime Loft of Main Street

16. Walk to Main | Pet-Friendly Yard & Workspace

Walk to Main | Pet-Friendly Yard & Workspace
St. Charles Historic District
10.0 out of 10, Exceptional, (11 reviews)
"I will stay here again. It was a great location for my visit. Lots of room and amenities. Highly recommend this location if you are visiting the St Louis area. Barely a mile to get to Hwy 70, so easy access to St Louis, St Peter's, Wentzville etc. Maybe two blocks from Historic St Charles and Ameristar Casino."
United States
Karen M.
The price is HK$999
HK$2,190 total
includes taxes & fees
8 Sept - 9 Sept
Walk to Main | Pet-Friendly Yard & Workspace

17. Historic Main St 2BR | Steps to Shops

Historic Main St 2BR | Steps to Shops
St. Charles Historic District
9.4 out of 10, Exceptional, (42 reviews)
"This property has a nice renovation while keeping a lot of its original character. Very clean and comfortable beds as well. The location couldn’t be better! We really enjoyed our stay."
United States
William O.
The price is HK$864
HK$3,004 total
includes taxes & fees
9 Sept - 10 Sept
Historic Main St 2BR | Steps to Shops

18. 1st Capitol Mansion - Suite 401

1st Capitol Mansion - Suite 401
St. Charles Historic District
7.4 out of 10, Good, (9 reviews)
"Nice property and a great location to all the shops and restaurants that St. Charles has to offer. The place was clean and nicely updated. Will definitely stay here again!"
United States
Emily L.
The price is HK$776
HK$1,998 total
includes taxes & fees
6 Sept - 7 Sept
1st Capitol Mansion - Suite 401

19. Walk to Main St | Pet-Friendly Apt

Walk to Main St | Pet-Friendly Apt
St. Charles Historic District
8.6 out of 10, Excellent, (17 reviews)
"Property was as advertised. Perfect for my needs, clean, quiet and convenient. Loved Historic St. Charles. Would recommend anytime! Thank you! "
United States
Brian B.
The price is HK$999
HK$2,391 total
includes taxes & fees
7 Sept - 8 Sept
Walk to Main St | Pet-Friendly Apt

20. Historic Main St. Customs House Upstairs Apartment

Historic Main St. Customs House Upstairs Apartment
St. Charles Historic District
9.6 out of 10, Exceptional, (39 reviews)
"Lovely place to stay!"
United States
Margaret A.
The price is HK$1,059
HK$2,855 total
includes taxes & fees
6 Sept - 7 Sept
Historic Main St. Customs House Upstairs Apartment
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Defiance Hotel Reviews

Find out more about Defiance

Defiance Apartments information

Number of reviews
9,557
Accommodation
113 Apartments
Lowest Price
HK$763
Highest Price
HK$1,733

Frequently asked questions

What's it like to stay at an apartment in Defiance?
You'll find 10 apartments to choose from in Defiance for your holiday.
Why would you choose apartments instead of traditional hotels?
An apartment is often more spacious than a traditional hotel room and comes with a kitchen, so you can cook some of your meals. Apartments are ideal for families who want the conveniences of home, and also for couples who want to stay away from the tourist areas.
What's the top apartment I should consider for a stay in Defiance?
Here are some of the top apartments in the area: The Lofts of North Main Street: Located in St. Charles , 19.2 mi/30.8 km from the heart of Defiance. Includes free WiFi, a sofa bed and a Smart TV . Access to on-site laundry facilities is available on site . 2 Queen Beds | Non-Smoking, Kitchen: Located 18.7 mi/30.1 km away in Maryland Heights . Free WiFi and a Smart TV are included . Prime Loft of Main Street: Located in St. Charles , 19.2 mi/30.9 km away. Includes free WiFi, a sofa bed and a Smart TV . Access to on-site laundry facilities is available on site . Historic Main St 1BR | Walk to Dining & Nightlife: 19.1 mi/30.7 km away in St. Charles . Amenities include a dining area . The Rustic Revival | Charming 2BR Retreat: It's located in St. Charles , 19 mi/30.6 km from Defiance. Includes free WiFi .
How many apartments will I find in Defiance?
Expedia has 10 apartments to book in Defiance.
What can I expect from the weather in Defiance?
Weather is only one factor, but it can really affect your travel plans, especially if you are planning a longer stay in Defiance. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.
What are the must-see places to visit in Defiance?
August A. Busch Memorial Conservation Area and Missouri River are a couple of scenic spots to enjoy the outdoors, whereas Historic Daniel Boone Home and Heritage Center is one of the cultural attractions. While here, Yellow Farmhouse Winery and Chandler Hill Vineyards are other places worth a visit.
What's the best way to get to and around Defiance?
Knowing a bit about the transportation options can you save you a headache when you get to your destination. Fly into St. Louis, MO (SUS-Spirit of St. Louis), which is located 7.5 mi (12 km) from the heart of the city. Otherwise, look for flights into Lambert-St. Louis International Airport (STL), which is 23.5 mi (37.8 km) away. If you'd like to explore around the area, consider renting a car to explore more sights.

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