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Check prices for these dates

In two weeks
1 May - 3 May
In two months
12 Jun - 14 Jun
In three months
10 Jul - 12 Jul
In four months
7 Aug - 9 Aug

Our top choices for Defiance apartments

Interior

2 Queen Beds | Mobil Access Tub Nsmk Kitchen

2 Queen Beds | Mobil Access Tub Nsmk Kitchen
St. Louis MO
The price is HK$682
HK$790 total
includes taxes & fees
19 Apr - 20 Apr
2 Queen Beds | Mobil Access Tub Nsmk Kitchen
Dining

Great for Business Travelers! Studio Suite Near Edward Jones! Shared Pool + Free Breakfast!

Great for Business Travelers! Studio Suite Near Edward Jones! Shared Pool + Free Breakfast!
Maryland Heights
9.6 out of 10, Exceptional, (4 reviews)
"It was an easy experience renting this place"
United States
Dominic M.
The price is HK$1,324
HK$1,692 total
includes taxes & fees
19 Apr - 20 Apr
Great for Business Travelers! Studio Suite Near Edward Jones! Shared Pool + Free Breakfast!
TV

Main Street Balcony Apartment

Main Street Balcony Apartment
St. Charles Historic District
9.6 out of 10, Exceptional, (36 reviews)
"Great location for shopping and a lot of restaurants nearby. Beds were very comfortable. "
United States
Brooke I.
The price is HK$1,203
HK$3,401 total
includes taxes & fees
20 Apr - 21 Apr
Main Street Balcony Apartment
Interior

The Lilly Pad House - Doddridge

The Lilly Pad House - Doddridge
Maryland Heights
The price is HK$1,488
HK$3,447 total
includes taxes & fees
16 Apr - 17 Apr
The Lilly Pad House - Doddridge
Interior

AK`s STL Pearl Grey House - Game Room

AK`s STL Pearl Grey House - Game Room
Maryland Heights
9.0 out of 10, Wonderful, (8 reviews)
"Great stay! We had everything we needed and the communication was perfect!"
United States
Melodie B.
The price is HK$1,340
HK$3,274 total
includes taxes & fees
19 Apr - 20 Apr
AK`s STL Pearl Grey House - Game Room
Exterior

Stay on Main Historic Studio

Stay on Main Historic Studio
St. Charles Historic District
9.0 out of 10, Wonderful, (33 reviews)
"Nice property.. Clean. "
United States
Belinda J.
The price is HK$617
HK$1,524 total
includes taxes & fees
16 Apr - 17 Apr
Stay on Main Historic Studio
1 bedroom, WiFi, bed sheets

Duplex Hideaway in St. Charles, MO

Duplex Hideaway in St. Charles, MO
St. Charles Historic District
10.0 out of 10, Exceptional, (5 reviews)
"I will stay here again. It was a great location for my visit. Lots of room and amenities. Highly recommend this location if you are visiting the St Louis area. Barely a mile to get to Hwy 70, so easy access to St Louis, St Peter's, Wentzville etc. Maybe two blocks from Historic St Charles and Ameristar Casino."
United States
Karen M.
The price is HK$754
HK$1,812 total
includes taxes & fees
21 Apr - 22 Apr
Duplex Hideaway in St. Charles, MO
Interior

Amazing Renovated Historic Loft on Main Street

Amazing Renovated Historic Loft on Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (59 reviews)
"Lovely accommodations, very clean, well equipped, great location. "
United States
Emily B.
The price is HK$1,089
HK$2,163 total
includes taxes & fees
3 May - 4 May
Amazing Renovated Historic Loft on Main Street
Interior

The Historic Bricks on Main

The Historic Bricks on Main
St. Charles Historic District
9.0 out of 10, Wonderful, (17 reviews)
"Host was very welcoming and helpful when we have any questions no matter what time of day. The place was very quaint and comfy. We would highly recommend. "
United States
Chelsea L.
The price is HK$853
HK$1,796 total
includes taxes & fees
19 Apr - 20 Apr
The Historic Bricks on Main
Interior

The Lofts of North Main Street

The Lofts of North Main Street
St. Charles Historic District
9.6 out of 10, Exceptional, (168 reviews)
"Host was very responsive and location was perfect"
United States
Peggy K.
The price is HK$980
HK$2,053 total
includes taxes & fees
22 Apr - 23 Apr
The Lofts of North Main Street
Interior

2 Bdr Upstairs Apt Walking Distance to Main St

2 Bdr Upstairs Apt Walking Distance to Main St
Saint Charles
7.6 out of 10, Good, (4 reviews)
"The best price-value ratio. Quiet neighborhood, close to the city center."
United States
Tamas P.
The price is HK$853
HK$2,268 total
includes taxes & fees
16 Apr - 17 Apr
2 Bdr Upstairs Apt Walking Distance to Main St
Fridge, microwave, oven, stovetop

Historic Main St. Customs House Upstairs Apartment

Historic Main St. Customs House Upstairs Apartment
St. Charles Historic District
9.6 out of 10, Exceptional, (36 reviews)
"Great Stay and great location! "
United States
Angela
The price is HK$1,028
HK$2,677 total
includes taxes & fees
16 Apr - 17 Apr
Historic Main St. Customs House Upstairs Apartment
Exterior

The Bourbon & Brass | Speakeasy-Inspired 2BDR

The Bourbon & Brass | Speakeasy-Inspired 2BDR
St. Charles Historic District
8.0 out of 10, Very good, (1 review)
"Room was fantastic! The grounds need to be cleaned up a bit."
United States
Marilyn
The price is HK$990
HK$2,508 total
includes taxes & fees
22 Apr - 23 Apr
The Bourbon & Brass | Speakeasy-Inspired 2BDR
TV

1st Capitol Mansion - Suite 401

1st Capitol Mansion - Suite 401
St. Charles Historic District
7.6 out of 10, Good, (8 reviews)
"Nice property and a great location to all the shops and restaurants that St. Charles has to offer. The place was clean and nicely updated. Will definitely stay here again!"
United States
Emily L.
The price is HK$776
HK$1,949 total
includes taxes & fees
16 Apr - 17 Apr
1st Capitol Mansion - Suite 401
Smart TV

Prime Loft of Main Street

Prime Loft of Main Street
St. Charles Historic District
9.8 out of 10, Exceptional, (107 reviews)
"This was a wonderful place for our St Charles stay - right in the heart of the historic downtown. Very clean and with nice character (exposed brick walls, tastefully decorated, etc). We had plenty of room fo the three of us, and our almost 12 year old kiddo LOVED having the loft upstairs to herself. If you are looking for a place to stay outside of St Louis, I highly recommend this location."
United States
Julie
The price is HK$1,089
HK$2,171 total
includes taxes & fees
20 Apr - 21 Apr
Prime Loft of Main Street
Fridge, microwave, stovetop, toaster

Charming Duplex on Main

Charming Duplex on Main
St. Charles Historic District
9.8 out of 10, Exceptional, (18 reviews)
"We had an AMAZING time here and you can't beat the close walking distance to main st!! Absolutely loved our stay. "
United States
Wendy K.
The price is HK$822
HK$1,892 total
includes taxes & fees
16 Apr - 17 Apr
Charming Duplex on Main
Interior

2 Queen Beds | Non-Smoking, Kitchen

2 Queen Beds | Non-Smoking, Kitchen
St. Louis MO
The price is HK$682
HK$790 total
includes taxes & fees
19 Apr - 20 Apr
2 Queen Beds | Non-Smoking, Kitchen
TV

Walk to Main St | Pet-Friendly Apt

Walk to Main St | Pet-Friendly Apt
St. Charles Historic District
8.8 out of 10, Excellent, (15 reviews)
"Great space! Very comfortable! "
United States
Mary H.
The price is HK$853
HK$2,268 total
includes taxes & fees
16 Apr - 17 Apr
Walk to Main St | Pet-Friendly Apt
TV

6th street 101 - Walk to Main St

6th street 101 - Walk to Main St
St. Charles Historic District
10.0 out of 10, Exceptional, (1 review)
The price is HK$776
HK$2,228 total
includes taxes & fees
23 Apr - 24 Apr
6th street 101 - Walk to Main St
Room

1 Queen Bed | Non-Smoking, Kitchen

1 Queen Bed | Non-Smoking, Kitchen
St. Louis MO
The price is HK$603
HK$700 total
includes taxes & fees
16 Apr - 17 Apr
1 Queen Bed | Non-Smoking, Kitchen
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Defiance Hotel Reviews

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

8/10 Good
"Overall, this was a pleasant stay at the Heritage Inn & Suites St. Louis/Fenton. The room was mostly clean and comfortable, though there was some used toilet paper left behind in the bathroom, which was a bit disappointing. Aside from that, the room met expectations. The front desk staff really stood out—everyone we interacted with was extremely nice, welcoming, and helpful, which made a great first impression. Breakfast was another highlight: it was warm, fresh, and offered a good variety of options, making it a great start to the day. On the downside, the pool was freezing and not very enjoyable. The hot tub was unfortunately full of children under 18, making it difficult for adults to relax, which may be something management should address. With a few improvements around cleanliness and pool management, this could be an even better stay. Overall, a decent experience with friendly service and a solid breakfast."
Shannon 1-night trip
Posted 2 hours ago
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Find out more about Defiance

Defiance Apartments information

Number of reviews
219
Accommodation
103 Apartments
Lowest Price
HK$700
Highest Price
HK$3,447

Frequently asked questions

What's it like to stay at an apartment in Defiance?
You'll find 10 apartments to choose from in Defiance for your holiday.
Why would you choose apartments instead of traditional hotels?
An apartment is often more spacious than a traditional hotel room and comes with a kitchen, so you can cook some of your meals. Apartments are ideal for families who want the conveniences of home, and also for couples who want to stay away from the tourist areas.
What's the top apartment I should consider for a stay in Defiance?
Here are some of the top apartments in the area: The Lofts of North Main Street: Located in St. Charles , 19.2 mi/30.8 km from the heart of Defiance. Includes free WiFi, a sofa bed and a Smart TV . Access to on-site laundry facilities is available on site . Prime Loft of Main Street: Located 19.2 mi/30.9 km away in St. Charles . Free WiFi, a sofa bed and a Smart TV are included . Access to on-site laundry facilities is available on site . The Headliner Suite on Main Street: Located in St. Charles , 18.5 mi/29.7 km away. Includes a sofa bed and a Smart TV . Access to on-site laundry facilities is available on site . Rhythm Loft Above the Honky Tonk: Located 19.1 mi/30.7 km away in St. Charles . Amenities include a Smart TV . Access to on-site laundry facilities is available on site . Main Street Balcony Apartment: Located in St. Charles , 19.2 mi/30.9 km from Defiance. Includes free WiFi and a balcony . Access to on-site laundry facilities is available on site .
How many apartments will I find in Defiance?
Expedia has 10 apartments to book in Defiance.
What can I expect from the weather in Defiance?
Weather is only one factor, but it can really affect your travel plans, especially if you are planning a longer stay in Defiance. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.
What are the must-see places to visit in Defiance?
Matson Hill Park Trailhead and August A. Busch Memorial Conservation Area are a couple of scenic spots to enjoy the outdoors, whereas Historic Daniel Boone Home and Heritage Center is one of the cultural attractions. While here, Chandler Hill Vineyards and Sugar Creek Winery are other places worth a visit.
What's the best way to get to and around Defiance?
Knowing a bit about the transportation options can you save you a headache when you get to your destination. Fly into St. Louis, MO (SUS-Spirit of St. Louis), which is located 7.5 mi (12 km) from the heart of the city. Otherwise, look for flights into Lambert-St. Louis International Airport (STL), which is 23.5 mi (37.8 km) away. If you'd like to explore around the area, consider renting a car to explore more sights.

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